Dyno
Dyno Therapeutics is an AI and biotechnology company building high-performance gene delivery technologies to unlock the potential of next-generation genetic medicine. Using its CapsidMap platform, which combines machine learning with high-throughput in vivo measurement, Dyno designs novel adeno-associated virus (AAV) capsids with improved tissue targeting, immune evasion, manufacturability, and payload capacity. Alongside its capsid partnerships, Dyno operates a public developer platform — Dyno Psi-Phi at design.dynotx.com — that exposes a REST API for agentic protein design: submit structure-prediction, inverse-folding and binder-scoring jobs against GPU-backed open models (AlphaFold2, ESMFold, ProteinMPNN, Boltz, ESM-2, RFDiffusion3, BoltzGen, OpenFold3), track job status, and retrieve scored results. The platform ships a first-party Python CLI (dyno-phi), an MIT-licensed open-source repository, and a provider-published Claude Code Agent Skill. Founded on research from George Church's lab at Harvard, Dyno is headquartered in Watertown, Massachusetts, and is an a16z Bio+Health portfolio company.
Dyno publishes 17 API contracts indexed on the APIs.io network, including Admin API, Agents API, Artifacts API, and 14 more. Tagged areas include Company, Biotechnology, Gene Therapy, Genetic Medicine, and Gene Delivery.
The Dyno catalog on APIs.io includes 1 Spectral governance ruleset.
Dyno’s developer surface includes documentation, API reference, getting-started guide, engineering blog, support, signup flow, CLI, and 28 more developer resources.
What this lets a business do 2
Business capabilities this provider's published APIs can perform, derived from its own contracts. Browse all capabilities →
Kin Score
Markets this provider is in provisional
The Kin Score Market layer reads a provider inside its market: its position, and how deep its integrations go. Depth is only comparable within a position. Provisional and unweighted: not part of the Kin Score or agent readiness.
| Market | Position | Depth | Registered MCP server | Declares compatibility |
|---|---|---|---|---|
| Cell & Gene Therapy | standard | 34.5 (thin) | - | - |
| GA4GH Genomics Standards (htsget, DRS, TES, WES, Beacon, Passports) | standard | 34.5 (thin) | - | - |
Registered MCP server and declares compatibility are report only — not weighted. Undeclared means we found nothing we can read, so there is no number: we never infer integrations.
Standards implemented 1
Standards this provider implements or carries. De facto ones are profiled and measured by the API Commons; formal ones come from the standards directory and are linked by the provider's own tags. The evidence column says how each claim was established — not that it was made.
APIs 17
Individual APIs this provider publishes, each with its own machine-readable definition.
Dyno Admin API
The admin API from Dyno — 5 operation(s) for admin.
Dyno Agents API
The agents API from Dyno — 3 operation(s) for agents.
Dyno Artifacts API
The Artifacts API from Dyno — 2 operation(s) for artifacts.
Dyno Assets API
The assets API from Dyno — 6 operation(s) for assets.
Dyno Auth API
The auth API from Dyno — 2 operation(s) for auth.
Dyno Datasets API
The datasets API from Dyno — 4 operation(s) for datasets.
Dyno Files API
The files API from Dyno — 2 operation(s) for files.
Dyno Health API
The Health API from Dyno — 1 operation(s) for health.
Dyno Ingest API
The ingest API from Dyno — 5 operation(s) for ingest.
Dyno Jobs API
The jobs API from Dyno — 7 operation(s) for jobs.
Dyno Phi API
The Phi API from Dyno — 2 operation(s) for phi.
Dyno Protocols API
The protocols API from Dyno — 7 operation(s) for protocols.
Dyno Research Notes API
The research-notes API from Dyno — 1 operation(s) for research-notes.
Dyno Runs API
The Runs API from Dyno — 4 operation(s) for runs.
Dyno Tools API
The tools API from Dyno — 3 operation(s) for tools.
Dyno Tutorial API
The tutorial API from Dyno — 1 operation(s) for tutorial.
Dyno Workflows API
The workflows API from Dyno — 9 operation(s) for workflows.
Scroll for all 17
Open Collections 1
Open, tool-agnostic API collections (OpenAPI-derived and Bruno).
Phi — Protein Design API
OPEN COLLECTIONAgent Skills 3
Packaged agent skills for driving this provider's APIs from an AI assistant.
Pricing Plans 1
Published pricing tiers and plan structures.
Dyno Plans Pricing
PLANSRate Limits 1
Documented rate limits and quota policies.
Dyno Rate Limits
RATE LIMITSFinOps 1
Cost, billing, and metering signals for API financial operations.
Dyno Finops
FINOPSSpectral Rules 1
Spectral governance rulesets for linting and validating these APIs.
Dyno API Rules
SPECTRALOpenAPI Overlays 1
Overlays applied on top of this provider's contracts. Each card says who wrote it: a document the provider publishes, or one API Evangelist derived or generated.
Dyno Phi Overlay
DERIVEDSecurity Posture 2
Authentication, domain security, vulnerability disclosure, and trust-center signals.
Resources
Get Started 4
Portal, sign-up, and the first successful call
Documentation 2
Reference material describing how the API behaves
Agent Surfaces 3
MCP servers, agent skills, and machine-readable catalogs
Design & Contract 5
Pagination, idempotency, versioning, errors, and events
Build 5
SDKs, sample code, and the tooling you integrate with
Access & Security 2
Authentication, authorization, and security posture
Operate 3
Status, limits, changes, and where to get help
Commercial 4
Pricing, plans, and the legal terms of use
Company 3
The organization behind the API
Other 4
Properties that don't map to a standard resource type
Source (apis.yml)
Dyno API — frequently asked questions
Does Dyno have an API?
Yes. APIs.io lists 17 APIs from Dyno, including Dyno Admin API, Dyno Agents API and Dyno Artifacts API, and 14 more.
Is there an OpenAPI specification for the Dyno API?
Yes. APIs.io indexes 17 OpenAPI specifications for Dyno, each linked for download from this page.
How do I authenticate with the Dyno API?
Dyno uses bearer-token authentication (apiKey/http-bearer/oidc-session · 3 schemes). The details are profiled on APIs.io as Dyno Authentication.
Is the Dyno API ready for AI agents?
Dyno has a Kin Score of 47.4 out of 100 (developing) and an Agent Readiness score of 31.9 (agent-ready), scored by API Evangelist on 2026-11-02.
Work with this as data
Every provider here is available over the APIs.io API and to AI agents over MCP.