OpenClinica
OpenClinica is a clinical-trial electronic data capture (EDC) and clinical data management platform used to build studies, capture case report form (CRF) data, schedule study events, and manage participants across sites. It ships as a free, open-source Community Edition (LGPL) and as a fully supported, hosted Enterprise Edition. OpenClinica exposes a documented REST web services API - authenticated with OAuth 2.0 bearer tokens - for programmatically adding and updating participants (single and bulk), scheduling and updating study events, and importing and retrieving clinical data. Data is interchanged using the CDISC ODM (Operational Data Model) standard as XML or JSON, so studies remain portable and standards-based.
OpenClinica publishes 6 API contracts indexed on the APIs.io network, including Authentication API, Bulk Operations API, Clinical Data API, and 3 more. Tagged areas include Clinical Trials, Electronic Data Capture, EDC, Clinical Data Management, and CDISC ODM.
The OpenClinica catalog on APIs.io includes 1 Spectral governance ruleset.
OpenClinica’s developer surface includes engineering blog, authentication, documentation, and 10 more developer resources.
Kin Score
Standards implemented 1
Standards this provider implements or carries. De facto ones are profiled and measured by the API Commons; formal ones come from the standards directory and are linked by the provider's own tags. The evidence column says how each claim was established — not that it was made.
APIs 6
Individual APIs this provider publishes, each with its own machine-readable definition.
OpenClinica Authentication API
OAuth 2.0 token acquisition.
OpenClinica Bulk Operations API
Bulk participant and event operations plus the bulk actions log.
OpenClinica Clinical Data API
Import and retrieve CRF data using CDISC ODM.
OpenClinica Metadata API
Read ODM study design metadata.
OpenClinica Participants API
Study participants (subjects) - add, update, list, and extract contact info.
OpenClinica Study Events API
Scheduling and updating study events (visits) for participants.
Open Collections 7
Open, tool-agnostic API collections (OpenAPI-derived and Bruno).
OpenClinica REST Authentication API
OPEN COLLECTIONOpenClinica REST Authentication Bulk Operations API
OPEN COLLECTIONOpenClinica REST Authentication Clinical Data API
OPEN COLLECTIONOpenClinica REST Authentication Metadata API
OPEN COLLECTIONOpenClinica REST Authentication Participants API
OPEN COLLECTIONOpenClinica REST Authentication Study Events API
OPEN COLLECTIONOpenClinica REST API
OPEN COLLECTIONScroll for all 7
OpenClinica API pricing
Not yet checked against OpenClinica's own pricing page. Compiled by API Evangelist on 2026-07-05 from www.openclinica.com/; confirm before you rely on a figure. A free plan or tier is listed.
| Plan | Price |
|---|---|
| Community Edition (Open Source) free | — |
| Enterprise Edition enterprise | — |
Plan details, limits and sources →
Rate limits
- REST API Requests: not published requests
- Self-Hosted Throughput: hardware-bound requests
- Bulk Operation Size: configurable via payload records
Compiled by API Evangelist, not yet checked against OpenClinica's documentation. All 4 limits →
Pricing Plans 1
Published pricing tiers and plan structures.
Rate Limits 1
Documented rate limits and quota policies.
OpenClinica Rate Limits
RATE LIMITSFinOps 1
Cost, billing, and metering signals for API financial operations.
OpenClinica Finops
FINOPSSpectral Rules 1
Spectral governance rulesets for linting and validating these APIs. Counts are the severity each rule declares, not results of running them.
OpenClinica API Rules
SPECTRALSecurity Posture 3
Authentication, domain security, vulnerability disclosure, and trust-center signals.
Agentic Access (API Evangelist recommendations) 1
Recommended x-agentic-access execution contracts for AI agents.
Resources
Documentation 1
Reference material describing how the API behaves
Agent Surfaces 1
MCP servers, agent skills, and machine-readable catalogs
Build 1
SDKs, sample code, and the tooling you integrate with
Access & Security 3
Authentication, authorization, and security posture
Operate 1
Status, limits, changes, and where to get help
Commercial 2
Pricing, plans, and the legal terms of use
Company 4
The organization behind the API
Source (apis.yml)
OpenClinica API — frequently asked questions
Does OpenClinica have an API?
Yes. APIs.io lists 6 APIs from OpenClinica, including OpenClinica Authentication API, OpenClinica Bulk Operations API and OpenClinica Clinical Data API, and 3 more.
Is there an OpenAPI specification for the OpenClinica API?
Yes. APIs.io indexes 6 OpenAPI specifications for OpenClinica, each linked for download from this page.
How do I authenticate with the OpenClinica API?
OpenClinica uses bearer-token authentication (http · 1 scheme). The details are profiled on APIs.io as OpenClinica Authentication.
How much does the OpenClinica API cost?
APIs.io lists 2 pricing plans for OpenClinica, with each plan's price, limits and inclusions under Pricing on this page.
Is the OpenClinica API ready for AI agents?
OpenClinica has a Kin Score of 23.5 out of 100 (emerging) and an Agent Readiness score of 21.3 (agent-aware), scored by API Evangelist on 2026-11-13.
Work with this as data
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