Cancer.gov
Cancer.gov is the web presence of the National Cancer Institute (NCI), the U.S. federal government's principal agency for cancer research and training. NCI and its partner programs expose a rich set of open APIs covering cancer clinical trials, genomic data, cancer-incidence surveillance, research data and models, terminology and vocabularies, and PDQ content — giving researchers, advocacy groups, clinicians, and application developers programmatic access to authoritative cancer data and content.
Cancer.gov publishes 48 API contracts indexed on the APIs.io network, including Diseases API, Interventions API, Terms API, and 45 more. Tagged areas include Cancer, Federal Government, Healthcare, Research, and Clinical Trials.
The Cancer.gov catalog on APIs.io includes 1 Spectral governance ruleset.
Cancer.gov’s developer surface includes authentication, engineering blog, CLI, changelog, documentation, API reference, signup flow, and 41 more developer resources.
What this lets a business do 1
Business capabilities this provider's published APIs can perform, derived from its own contracts. Browse all capabilities →
Kin Score
Markets this provider is in provisional
The Kin Score Market layer reads a provider inside its market: its position, and how deep its integrations go. Depth is only comparable within a position. Provisional and unweighted: not part of the Kin Score or agent readiness.
| Market | Position | Depth | Registered MCP server | Declares compatibility |
|---|---|---|---|---|
| Life Sciences (Biotech and Pharma R&D) | standard | 17.2 (thin) | - | - |
| US Federal API Programs (api.data.gov, Login.gov, GSA MAS, FedRAMP) | standard | 17.2 (thin) | - | - |
| GA4GH Genomics Standards (htsget, DRS, TES, WES, Beacon, Passports) | standard | 17.2 (thin) | - | - |
Registered MCP server and declares compatibility are report only — not weighted. Undeclared means we found nothing we can read, so there is no number: we never infer integrations.
Standards implemented 1
Standards this provider implements or carries. De facto ones are profiled and measured by the API Commons; formal ones come from the standards directory and are linked by the provider's own tags. The evidence column says how each claim was established — not that it was made.
APIs 48
Individual APIs this provider publishes, each with its own machine-readable definition.
NCI Clinical Trials Search API
RESTful API that lets developers build applications, search tools, and digital platforms over NCI-supported cancer clinical trials data sourced from NCI's Clinical Trials Report...
NCI Genomic Data Commons (GDC) API
The external-facing REST interface for the NCI Genomic Data Commons. Drives the GDC Data Portal and GDC Submission Portal and is open for programmatic access. Provides query, do...
NCI Content Syndication Services
A suite of syndicated content channels — RSS feeds, the NCI Dictionary Widget, and syndicated publication content — that partner sites and health platforms can embed to deliver ...
Cancer.gov Diseases API
The Diseases API from Cancer.gov — 1 operation(s) for diseases.
Cancer.gov Interventions API
The Interventions API from Cancer.gov — 1 operation(s) for interventions.
Cancer.gov Terms API
The Terms API from Cancer.gov — 1 operation(s) for terms.
Cancer.gov Trials API
The Trials API from Cancer.gov — 2 operation(s) for trials.
Cancer.gov Application version endpoint API
The Application version endpoint API from Cancer.gov — 1 operation(s) for application version endpoint.
Cancer.gov Asset Details Controller API
The asset-details-controller API from Cancer.gov — 1 operation(s) for asset-details-controller.
Cancer.gov Autosuggest API
The Autosuggest API from Cancer.gov — 4 operation(s) for autosuggest.
Cancer.gov Concept endpoints API
The Concept endpoints API from Cancer.gov — 21 operation(s) for concept endpoints.
Cancer.gov Delete Collection Controller API
The delete-collection-controller API from Cancer.gov — 1 operation(s) for delete-collection-controller.
Cancer.gov Delete Data File Controller API
The delete-data-file-controller API from Cancer.gov — 1 operation(s) for delete-data-file-controller.
Cancer.gov Delete Predictions Controller API
The delete-predictions-controller API from Cancer.gov — 1 operation(s) for delete-predictions-controller.
Cancer.gov Disease API
Hematopoietic, lymphoid neoplasms and solid tumor diseases
Cancer.gov Doe Collection Controller API
The doe-collection-controller API from Cancer.gov — 1 operation(s) for doe-collection-controller.
Cancer.gov Doe Create Bulk Datafile Controller API
The doe-create-bulk-datafile-controller API from Cancer.gov — 1 operation(s) for doe-create-bulk-datafile-controller.
Cancer.gov Doe Create Collection Controller API
The doe-create-collection-controller API from Cancer.gov — 1 operation(s) for doe-create-collection-controller.
Cancer.gov Doe Create Datafile Controller API
The doe-create-datafile-controller API from Cancer.gov — 1 operation(s) for doe-create-datafile-controller.
Cancer.gov Doe Download Controller API
The doe-download-controller API from Cancer.gov — 1 operation(s) for doe-download-controller.
Cancer.gov Doe Download Files Controller API
The doe-download-files-controller API from Cancer.gov — 1 operation(s) for doe-download-files-controller.
Cancer.gov Doe Retry Download Task Controller API
The doe-retry-download-task-controller API from Cancer.gov — 1 operation(s) for doe-retry-download-task-controller.
Cancer.gov Doe Retry Uploadtask Controller API
The doe-retry-uploadtask-controller API from Cancer.gov — 1 operation(s) for doe-retry-uploadtask-controller.
Cancer.gov Doe Sync Download Controller API
The doe-sync-download-controller API from Cancer.gov — 1 operation(s) for doe-sync-download-controller.
Cancer.gov Drugs API
The Drugs API from Cancer.gov — 6 operation(s) for drugs.
Cancer.gov Glossary API
A glossary of cancer-related terms
Cancer.gov Hcpcs API
Healthcare Common Procedure Coding Systems (HCPCS) nomenclatures
Cancer.gov History endpoints API
The History endpoints API from Cancer.gov — 2 operation(s) for history endpoints.
Cancer.gov Home Controller API
The home-controller API from Cancer.gov — 1 operation(s) for home-controller.
Cancer.gov Mapset endpoints API
The Mapset endpoints API from Cancer.gov — 3 operation(s) for mapset endpoints.
Cancer.gov Metadata endpoints API
The Metadata endpoints API from Cancer.gov — 24 operation(s) for metadata endpoints.
Cancer.gov Mph API
Multiple Primary and Histology Coding Rules
Cancer.gov Naaccr API
NAACCR Documentation
Cancer.gov Ndc API
A searchable mirror of National Drug Codes (NDC)
Cancer.gov Perform Inferencing Controller API
The perform-inferencing-controller API from Cancer.gov — 2 operation(s) for perform-inferencing-controller.
Cancer.gov Recode API
Recode algorithms
Cancer.gov Release Notes Notifications Controller API
The release-notes-notifications-controller API from Cancer.gov — 1 operation(s) for release-notes-notifications-controller.
Cancer.gov Resource API
The Resource API from Cancer.gov — 1 operation(s) for resource.
Cancer.gov Resources API
The Resources API from Cancer.gov — 1 operation(s) for resources.
Cancer.gov Rest API Common Controller API
The rest-api-common-controller API from Cancer.gov — 17 operation(s) for rest-api-common-controller.
Cancer.gov Rx API
Antineoplastic drugs database
Cancer.gov Search API
The Search API from Cancer.gov — 2 operation(s) for search.
Cancer.gov Search endpoint API
The Search endpoint API from Cancer.gov — 4 operation(s) for search endpoint.
Cancer.gov Staging API
Staging Algorithms
Cancer.gov Subset endpoints API
The Subset endpoints API from Cancer.gov — 3 operation(s) for subset endpoints.
Cancer.gov Surgery API
SEER Site-Specific Surgery Codes
Cancer.gov Best Bets API
The Best Bets API from Cancer.gov — 2 operation(s) for best bets.
Cancer.gov Health Check API
The Health Check API from Cancer.gov — 1 operation(s) for health check.
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Open Collections 5
Open, tool-agnostic API collections (OpenAPI-derived and Bruno).
NCI Clinical Trials Search Diseases API
OPEN COLLECTIONNCI Clinical Trials Search Diseases Interventions API
OPEN COLLECTIONNCI Clinical Trials Search Diseases Terms API
OPEN COLLECTIONNCI Clinical Search Diseases Trials API
OPEN COLLECTIONNCI Clinical Trials Search API
OPEN COLLECTIONMCP Servers 1
Model Context Protocol servers that expose these APIs to AI agents.
Cancer.gov MCP Server
MCP server; 143 tools listed. A candidate, not confirmed as published by the provider.
MCP SERVERAgent Skills 5
Packaged agent skills for driving this provider's APIs from an AI assistant.
look-up-a-cancer-drug
AGENT SKILLlook-up-a-cancer-term
AGENT SKILLquery-genomic-data-commons
AGENT SKILLresolve-an-nci-thesaurus-concept
AGENT SKILLsearch-clinical-trials
AGENT SKILLPricing Plans 1
Published pricing tiers and plan structures.
Rate Limits 1
Documented rate limits and quota policies.
Cancer Gov Rate Limits
RATE LIMITSFinOps 1
Cost, billing, and metering signals for API financial operations.
Cancer Gov Finops
FINOPSSpectral Rules 1
Spectral governance rulesets for linting and validating these APIs.
Cancer.gov API Rules
SPECTRALOpenAPI Overlays 8
Overlays applied on top of this provider's contracts. Each card says who wrote it: a document the provider publishes, or one API Evangelist derived or generated.
Cancer Gov Best Bets Overlay
DERIVEDCancer Gov Evs Overlay
DERIVEDCancer Gov Glossary Overlay
DERIVEDCancer Gov Modac Overlay
DERIVEDCancer Gov R4R Overlay
DERIVEDCancer Gov Seer Overlay
DERIVEDScroll for all 8
Security Posture 2
Authentication, domain security, vulnerability disclosure, and trust-center signals.
Agentic Access 1
Recommended x-agentic-access execution contracts for AI agents.
Resources
Get Started 3
Portal, sign-up, and the first successful call
Documentation 3
Reference material describing how the API behaves
Agent Surfaces 4
MCP servers, agent skills, and machine-readable catalogs
Design & Contract 6
Pagination, idempotency, versioning, errors, and events
Build 5
SDKs, sample code, and the tooling you integrate with
Access & Security 2
Authentication, authorization, and security posture
Operate 4
Status, limits, changes, and where to get help
Commercial 4
Pricing, plans, and the legal terms of use
Company 3
The organization behind the API
Other 14
Properties that don't map to a standard resource type
Scroll for all 14
Source (apis.yml)
Cancer.gov API — frequently asked questions
Does Cancer.gov have an API?
Yes. APIs.io lists 48 APIs from Cancer.gov, including NCI Clinical Trials Search API, NCI Genomic Data Commons (GDC) API and NCI Content Syndication Services, and 45 more.
Is there an OpenAPI specification for the Cancer.gov API?
Yes. APIs.io indexes 45 OpenAPI specifications for Cancer.gov, each linked for download from this page.
How do I authenticate with the Cancer.gov API?
Cancer.gov uses bearer-token authentication (apiKey/none · 5 schemes). The details are profiled on APIs.io as Cancer Gov Authentication.
How much does the Cancer.gov API cost?
APIs.io lists 1 pricing plan for Cancer.gov, with each plan's price, limits and inclusions under Pricing Plans on this page.
Does Cancer.gov have an MCP server?
Yes. APIs.io lists 1 MCP server for Cancer.gov: MCP server; 143 tools listed. A candidate, not confirmed as published by the provider.
Is the Cancer.gov API ready for AI agents?
Cancer.gov has a Kin Score of 50.5 out of 100 (developing) and an Agent Readiness score of 31.1 (agent-ready), scored by API Evangelist on 2026-11-02.
Work with this as data
Every provider here is available over the APIs.io API and to AI agents over MCP.