Cancer.gov website screenshot

Cancer.gov

Cancer.gov is the web presence of the National Cancer Institute (NCI), the U.S. federal government's principal agency for cancer research and training. NCI and its partner programs expose a rich set of open APIs covering cancer clinical trials, genomic data, cancer-incidence surveillance, research data and models, terminology and vocabularies, and PDQ content — giving researchers, advocacy groups, clinicians, and application developers programmatic access to authoritative cancer data and content.

Cancer.gov publishes 4 APIs on the APIs.io network, including Diseases API, Interventions API, Terms API, and 1 more. Tagged areas include Cancer, Federal Government, Healthcare, Research, and Clinical Trials.

Cancer.gov’s developer surface includes authentication, developer portal, engineering blog, and 9 more developer resources.

35.4/100 thin ▬ flat Agent 31/100 agent aware Full breakdown ↓
scored 2026-07-28 · rubric v0.6
AccessFreemiumSelf serve⚡ Free to try
10 APIs
CancerFederal GovernmentHealthcareResearchClinical TrialsGenomicsSurveillanceOpen Data

Kin Score

Kin Score Kin Score How this is scored →
scored 2026-07-28 · rubric v0.6
Composite quality — 35.4/100 · thin
Contract Quality 12.5 / 25
Developer Ergonomics 4.3 / 20
Commercial Clarity 10.0 / 20
Operational Transparency 4.8 / 13
Governance 0.0 / 12
Discoverability 6.5 / 10
Agent readiness — 31/100 · agent aware
Machine-Readable Contract 18 / 18
Agentic Access Contract 10 / 10
MCP Server 0 / 12
Machine-Readable Auth 10 / 10
Idempotency 0 / 9
Stable Error Semantics 0 / 8
Request/Response Examples 0 / 7
Rate-Limit Signaling 7 / 7
Typed Event Surface 0 / 6
Agent Skills 0 / 5
Well-Known Catalog 0 / 4
Consent & Bot Identity 0 / 3
A2A Agent Card 0 / 8
Dry-Run / Simulate Mode 0 / 4
Improve this rating by publishing the missing artifacts — every area above can be raised, and the full rubric is at apis.io/rating/. This rating is computed from github.com/api-evangelist/cancer-gov: open an issue to ask a question, or submit a pull request to add artifacts. Want it done for you? Prioritized profiling — $2,500 →

APIs 10

Individual APIs this provider publishes, each with its own machine-readable definition.

NCI Clinical Trials Search API

RESTful API that lets developers build applications, search tools, and digital platforms over NCI-supported cancer clinical trials data sourced from NCI's Clinical Trials Report...

NCI Genomic Data Commons (GDC) API

The external-facing REST interface for the NCI Genomic Data Commons. Drives the GDC Data Portal and GDC Submission Portal and is open for programmatic access. Provides query, do...

NCI SEER API

RESTful API for the Surveillance, Epidemiology, and End Results (SEER) Program. Supports SEER datasets plus staging APIs for cancer staging (TNM and Collaborative Stage algorith...

NCI MoDaC API

The NCI Model and Data Clearinghouse (MoDaC) API provides programmatic access to cancer research data, computational models, and associated tools hosted in MoDaC. Developers can...

NCI EVS Terminology API

Enterprise Vocabulary Services (EVS) exposes NCI Thesaurus and NCI Metathesaurus content — over 192,000 concepts, 154,000 textual definitions, 623,000 synonyms and 630,000 inter...

NCI Content Syndication Services

A suite of syndicated content channels — RSS feeds, the NCI Dictionary Widget, and syndicated publication content — that partner sites and health platforms can embed to deliver ...

Cancer.gov Diseases API

The Diseases API from Cancer.gov — 1 operation(s) for diseases.

Cancer.gov Interventions API

The Interventions API from Cancer.gov — 1 operation(s) for interventions.

Cancer.gov Terms API

The Terms API from Cancer.gov — 1 operation(s) for terms.

Cancer.gov Trials API

The Trials API from Cancer.gov — 2 operation(s) for trials.

Scroll for all 10

Open Collections 1

Open, tool-agnostic API collections (OpenAPI-derived and Bruno).

Pricing Plans 1

Published pricing tiers and plan structures.

Rate Limits 1

Documented rate limits and quota policies.

Cancer Gov Rate Limits

5 limits

RATE LIMITS

FinOps 1

Cost, billing, and metering signals for API financial operations.

Security Posture 2

Authentication, domain security, vulnerability disclosure, and trust-center signals.

Cancer Gov Authentication

apiKey · 1 scheme

SECURITY

Cancer Gov Domain Security

TLSv1.3 · HSTS · DNSSEC · DMARC

SECURITY

Agentic Access 1

Recommended x-agentic-access execution contracts for AI agents.

Cancer Gov Agentic Access

6 operations · 1 acting

6 operations · 1 acting

AGENTIC

Resources

Get Started 1

Portal, sign-up, and the first successful call

Agent Surfaces 1

MCP servers, agent skills, and machine-readable catalogs

Build 1

SDKs, sample code, and the tooling you integrate with

Access & Security 2

Authentication, authorization, and security posture

Commercial 1

Pricing, plans, and the legal terms of use

Company 2

The organization behind the API

Other 4

Properties that don't map to a standard resource type

Source (apis.yml)

apis.yml Raw ↑
aid: cancer-gov
name: Cancer.gov
url: https://raw.githubusercontent.com/api-evangelist/cancer-gov/refs/heads/main/apis.yml
accessModel:
  pricing: freemium
  onboarding: self-serve
  trial: false
  try_now: true
  public: false
  label: Freemium · Self-serve signup
  confidence: high
  source:
  - plans
  - authentication
  generated: '2026-07-22'
  method: derived
image: https://kinlane-images.s3.amazonaws.com/shared/apis-json/icons/cancer-gov.png
type: Index
tags:
- Cancer
- Federal Government
- Healthcare
- Research
- Clinical Trials
- Genomics
- Surveillance
- Open Data
access: Open
created: '2024-07-02'
modified: '2026-04-23'
position: Provider
specificationVersion: '0.19'
description: Cancer.gov is the web presence of the National Cancer Institute (NCI), the U.S. federal government's principal
  agency for cancer research and training. NCI and its partner programs expose a rich set of open APIs covering cancer clinical
  trials, genomic data, cancer-incidence surveillance, research data and models, terminology and vocabularies, and PDQ content
  — giving researchers, advocacy groups, clinicians, and application developers programmatic access to authoritative cancer
  data and content.
apis:
- aid: cancer-gov:clinical-trials-api
  name: NCI Clinical Trials Search API
  description: RESTful API that lets developers build applications, search tools, and digital platforms over NCI-supported
    cancer clinical trials data sourced from NCI's Clinical Trials Reporting Program (CTRP). The same API powers NCI's public
    Clinical Trials Search. Developers register for a free API key through the CTS Developer Accounts portal.
  humanURL: https://clinicaltrialsapi.cancer.gov/
  baseURL: https://clinicaltrialsapi.cancer.gov/api/v2
  tags:
  - Clinical Trials
  - CTRP
  - Research
  properties:
  - type: Documentation
    url: https://clinicaltrialsapi.cancer.gov/
  - type: Signup
    url: https://clinicaltrialsapi.cancer.gov/
  - type: ParentPage
    url: https://www.cancer.gov/syndication/api
- aid: cancer-gov:gdc-api
  name: NCI Genomic Data Commons (GDC) API
  description: The external-facing REST interface for the NCI Genomic Data Commons. Drives the GDC Data Portal and GDC Submission
    Portal and is open for programmatic access. Provides query, download, and submission endpoints for cancer genomics datasets
    including TCGA, TARGET, CPTAC, and other NCI-funded genomic programs.
  humanURL: https://gdc.cancer.gov/developers/gdc-application-programming-interface-api
  baseURL: https://api.gdc.cancer.gov
  tags:
  - Genomics
  - TCGA
  - Research Data
  properties:
  - type: Documentation
    url: https://docs.gdc.cancer.gov/API/Users_Guide/Getting_Started/
  - type: Reference
    url: https://docs.gdc.cancer.gov/Encyclopedia/pages/REST_API/
  - type: Portal
    url: https://portal.gdc.cancer.gov/
- aid: cancer-gov:seer-api
  name: NCI SEER API
  description: RESTful API for the Surveillance, Epidemiology, and End Results (SEER) Program. Supports SEER datasets plus
    staging APIs for cancer staging (TNM and Collaborative Stage algorithms), enabling developers to embed authoritative incidence,
    survival, and staging logic into their own systems.
  humanURL: https://api.seer.cancer.gov/
  baseURL: https://api.seer.cancer.gov
  tags:
  - Surveillance
  - Epidemiology
  - Staging
  - SEER
  properties:
  - type: Documentation
    url: https://api.seer.cancer.gov/docs
  - type: Portal
    url: https://api.seer.cancer.gov/
- aid: cancer-gov:modac-api
  name: NCI MoDaC API
  description: The NCI Model and Data Clearinghouse (MoDaC) API provides programmatic access to cancer research data, computational
    models, and associated tools hosted in MoDaC. Developers can search, retrieve metadata, and download model/data artifacts
    produced by NCI-funded research programs.
  humanURL: https://modac.cancer.gov/
  tags:
  - Research Data
  - Models
  - Clearinghouse
  properties:
  - type: Documentation
    url: https://modac.cancer.gov/swagger-ui/4.14.0/index.html
  - type: Portal
    url: https://modac.cancer.gov/
- aid: cancer-gov:evs-api
  name: NCI EVS Terminology API
  description: Enterprise Vocabulary Services (EVS) exposes NCI Thesaurus and NCI Metathesaurus content — over 192,000 concepts,
    154,000 textual definitions, 623,000 synonyms and 630,000 inter-concept relationships — through a search and browse API
    used to code, analyze, and share cancer and biomedical research information.
  humanURL: https://evs.nci.nih.gov/
  tags:
  - Terminology
  - Vocabulary
  - NCI Thesaurus
  properties:
  - type: Documentation
    url: https://evs.nci.nih.gov/
  - type: Explorer
    url: https://evsexplore.semantics.cancer.gov/
  - type: WhitePaper
    url: https://evs.nci.nih.gov/ftp1/NCI_Metathesaurus/EVS%20Metathesaurus%20White%20Paper.pdf
- aid: cancer-gov:syndication-services
  name: NCI Content Syndication Services
  description: A suite of syndicated content channels — RSS feeds, the NCI Dictionary Widget, and syndicated publication content
    — that partner sites and health platforms can embed to deliver authoritative cancer content sourced from cancer.gov.
  humanURL: https://www.cancer.gov/syndication
  tags:
  - Syndication
  - Content
  - Widgets
  - RSS
  properties:
  - type: Documentation
    url: https://www.cancer.gov/syndication
- aid: cancer-gov:cancer-gov-diseases-api
  name: Cancer.gov Diseases API
  description: The Diseases API from Cancer.gov — 1 operation(s) for diseases.
  humanURL: https://clinicaltrialsapi.cancer.gov/
  baseURL: https://clinicaltrialsapi.cancer.gov/api/v2
  tags:
  - Diseases
  properties:
  - type: OpenAPI
    url: openapi/cancer-gov-diseases-api-openapi.yml
- aid: cancer-gov:cancer-gov-interventions-api
  name: Cancer.gov Interventions API
  description: The Interventions API from Cancer.gov — 1 operation(s) for interventions.
  humanURL: https://clinicaltrialsapi.cancer.gov/
  baseURL: https://clinicaltrialsapi.cancer.gov/api/v2
  tags:
  - Interventions
  properties:
  - type: OpenAPI
    url: openapi/cancer-gov-interventions-api-openapi.yml
- aid: cancer-gov:cancer-gov-terms-api
  name: Cancer.gov Terms API
  description: The Terms API from Cancer.gov — 1 operation(s) for terms.
  humanURL: https://clinicaltrialsapi.cancer.gov/
  baseURL: https://clinicaltrialsapi.cancer.gov/api/v2
  tags:
  - Terms
  properties:
  - type: OpenAPI
    url: openapi/cancer-gov-terms-api-openapi.yml
- aid: cancer-gov:cancer-gov-trials-api
  name: Cancer.gov Trials API
  description: The Trials API from Cancer.gov — 2 operation(s) for trials.
  humanURL: https://clinicaltrialsapi.cancer.gov/
  baseURL: https://clinicaltrialsapi.cancer.gov/api/v2
  tags:
  - Trials
  properties:
  - type: OpenAPI
    url: openapi/cancer-gov-trials-api-openapi.yml
common:
- type: AgenticAccess
  url: agentic-access/cancer-gov-agentic-access.yml
- type: DomainSecurity
  url: security/cancer-gov-domain-security.yml
- type: Authentication
  url: authentication/cancer-gov-authentication.yml
- type: GitHubOrganization
  url: https://github.com/NCIOCPL
- type: Website
  url: https://www.cancer.gov/
- type: Portal
  url: https://api.cancer.gov/
- type: SyndicationServices
  url: https://www.cancer.gov/syndication
- type: DataScience
  url: https://datascience.cancer.gov/
- type: OpenDataPolicy
  url: https://www.cancer.gov/research/resources/open-science
- type: PrivacyPolicy
  url: https://www.cancer.gov/policies/privacy-security
- type: LicensingAndReuse
  url: https://www.cancer.gov/policies/copyright-reuse
- url: https://www.cancer.gov/publishedcontent/rss/news-events/cancer-currents-blog.rss
  type: Blog
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com