TwinStrand Biosciences

TwinStrand Biosciences is a Seattle, Washington genomics company founded in 2015 by Jesse Salk and Michael Schmitt that develops and commercializes Duplex Sequencing, an error-corrected next-generation-sequencing chemistry licensed from the University of Washington that independently tracks both strands of an individual DNA molecule and compares them, cutting sequencing error rates from roughly 1-in-100 to below 1-in-10,000,000 per nucleotide and making ultra-rare mutations detectable. The company sells DuplexSeq assay kits — a Mutagenesis Assay for genetic toxicology in human, rat and mouse models, an AML MRD Assay for minimal residual disease in acute myeloid leukemia, and a customizable assay — each paired with a proprietary cloud analysis pipeline that turns raw Illumina reads into duplex-consensus sequences, variant calls, mutation frequency, SBS spectra and assay quality metrics. That analysis software is not a public API: it is hosted on the DNAnexus platform and reachable only by customers through a DNAnexus project. TwinStrand publishes no developer portal, no API reference and no OpenAPI, AsyncAPI, GraphQL or Postman artifact of its own, and the api., docs. and developer. subdomains of twinstrandbio.com do not resolve. The only machine-readable surface on twinstrandbio.com is the WordPress REST API at /wp-json — 349 routes across 18 namespaces — whose wp/v2 content collections are anonymously readable and serve the company publication index, patent estate, conference posters, news releases, events, team profiles, pages and media library as JSON. Its public code lives in the github.com/twinstrandbio organization, which holds a single reference-data repository and no client libraries. The DuplexSeq Mutagenesis Assay business has since been transferred to Scantox, and Exact Sciences holds an exclusive license to the Duplex Sequencing technology.

TwinStrand Biosciences publishes 12 APIs on the APIs.io network, including Discovery API, Events API, Media API, and 9 more. Tagged areas include Company, Genomics, Biotechnology, Life Sciences, and DNA Sequencing.

TwinStrand Biosciences’ developer surface includes product news, legal docs, YouTube channel, authentication, and 21 more developer resources.

🌐 Visit website 📡 Source on GitHub
22.3/100 emerging ▬ flat Agent 26/100 agent aware Full breakdown ↓
scored 2026-08-12 · rubric v0.11.0
12 APIs
CompanyGenomicsBiotechnologyLife SciencesDNA SequencingNext Generation SequencingOncologyGenetic ToxicologyDiagnosticsBioinformaticsResearchContent

Kin Score

Kin Score Kin Score How this is scored →
scored 2026-08-12 · rubric v0.11.0
Composite quality — 22.3/100 · emerging
Contract Quality 3.2 / 21
Developer Ergonomics 2.1 / 17
Commercial Clarity 3.6 / 17
Operational Transparency 0.6 / 11
Governance 1.2 / 10
Discoverability 6.9 / 9
Regulatory Posture 4.7 / 15
Agent readiness — 26/100 · agent aware
Machine-Readable Contract 18 / 18
Agentic Access Contract 0 / 10
MCP Server 0 / 12
Machine-Readable Auth 10 / 10
Idempotency 0 / 9
Stable Error Semantics 0 / 8
Request/Response Examples 0 / 7
Rate-Limit Signaling 0 / 7
Typed Event Surface 0 / 6
Agent Skills 5 / 5
Well-Known Catalog 0 / 4
Consent & Bot Identity 0 / 3
A2A Agent Card 0 / 8
Dry-Run / Simulate Mode 0 / 4
Regulatory Posture applies to this provider. Its tags matched the Health regime, so Regulatory Posture carries 15 points of the composite. If this regime is wrong for your business, say so on your provider repo — the applicability map is public and we will correct it.
The six quality facets above are damped to 85 points between them, because the conditional facet above carries the other 15. That is why each facet's contribution is shown against a damped maximum: raising a quality facet moves the composite by 85% of its nominal weight, not 100%. The full arithmetic is at apis.io/rating/.
Improve this rating by publishing the missing artifacts — every area above can be raised, and the full rubric is at apis.io/rating/. This rating is computed from github.com/api-evangelist/twinstrand-biosciences: open an issue to ask a question, or submit a pull request to add artifacts. Want it done for you? Prioritized profiling — $2,500 →

APIs 12

Individual APIs this provider publishes, each with its own machine-readable definition.

TwinStrand Biosciences Discovery API

The Discovery API from TwinStrand Biosciences — 5 operation(s) for discovery.

TwinStrand Biosciences Events API

The Events API from TwinStrand Biosciences — 2 operation(s) for events.

TwinStrand Biosciences Media API

The Media API from TwinStrand Biosciences — 2 operation(s) for media.

TwinStrand Biosciences News API

The News API from TwinStrand Biosciences — 2 operation(s) for news.

TwinStrand Biosciences Pages API

The Pages API from TwinStrand Biosciences — 2 operation(s) for pages.

TwinStrand Biosciences Patents API

The Patents API from TwinStrand Biosciences — 2 operation(s) for patents.

TwinStrand Biosciences People API

The People API from TwinStrand Biosciences — 4 operation(s) for people.

TwinStrand Biosciences Posters API

The Posters API from TwinStrand Biosciences — 2 operation(s) for posters.

TwinStrand Biosciences Posts API

The Posts API from TwinStrand Biosciences — 2 operation(s) for posts.

TwinStrand Biosciences Publications API

The Publications API from TwinStrand Biosciences — 6 operation(s) for publications.

TwinStrand Biosciences Search API

The Search API from TwinStrand Biosciences — 1 operation(s) for search.

TwinStrand Biosciences Taxonomies API

The Taxonomies API from TwinStrand Biosciences — 4 operation(s) for taxonomies.

Scroll for all 12

Security Posture 2

Authentication, domain security, vulnerability disclosure, and trust-center signals.

Twinstrand Biosciences Authentication

http · 1 scheme

SECURITY

Twinstrand Biosciences Domain Security

TLSv1.3 · HSTS · DMARC

SECURITY

Resources

Agent Surfaces 3

MCP servers, agent skills, and machine-readable catalogs

LLMsTxt
LLMsTxt
 WellKnown
WellKnown
 AgentSkill
AgentSkill

Design & Contract 3

Pagination, idempotency, versioning, errors, and events

Conventions
Conventions
 Conformance
Conformance
 Lifecycle
Lifecycle

Build 2

SDKs, sample code, and the tooling you integrate with

GitHubOrganization
GitHubOrganization
 Packages
Packages

Access & Security 2

Authentication, authorization, and security posture

Authentication
Authentication
 DomainSecurity
DomainSecurity

Learn 1

Tutorials, courses, talks, and written guidance

YouTube
YouTube

Commercial 3

Pricing, plans, and the legal terms of use

TermsOfService
TermsOfService
 PrivacyPolicy
PrivacyPolicy
 Legal
Legal

Company 4

The organization behind the API

Website
Website
 About
About
 News
News
 Investors
Investors

Other 7

Properties that don't map to a standard resource type

Overlay
Overlay
 Team
Team
 Technology
Technology
 Publications
Publications
 Resources
Resources
 Patents
Patents
 SecondaryMarket
SecondaryMarket

Scroll for all 7

Source (apis.yml)

apis.yml Raw ↑ 
aid: twinstrand-biosciences
name: TwinStrand Biosciences
description: 'TwinStrand Biosciences is a Seattle, Washington genomics company founded in 2015 by Jesse Salk and Michael Schmitt
  that develops and commercializes Duplex Sequencing, an error-corrected next-generation-sequencing chemistry licensed from
  the University of Washington that independently tracks both strands of an individual DNA molecule and compares them, cutting
  sequencing error rates from roughly 1-in-100 to below 1-in-10,000,000 per nucleotide and making ultra-rare mutations detectable.
  The company sells DuplexSeq assay kits — a Mutagenesis Assay for genetic toxicology in human, rat and mouse models, an AML
  MRD Assay for minimal residual disease in acute myeloid leukemia, and a customizable assay — each paired with a proprietary
  cloud analysis pipeline that turns raw Illumina reads into duplex-consensus sequences, variant calls, mutation frequency,
  SBS spectra and assay quality metrics. That analysis software is not a public API: it is hosted on the DNAnexus platform
  and reachable only by customers through a DNAnexus project. TwinStrand publishes no developer portal, no API reference and
  no OpenAPI, AsyncAPI, GraphQL or Postman artifact of its own, and the api., docs. and developer. subdomains of twinstrandbio.com
  do not resolve. The only machine-readable surface on twinstrandbio.com is the WordPress REST API at /wp-json — 349 routes
  across 18 namespaces — whose wp/v2 content collections are anonymously readable and serve the company publication index,
  patent estate, conference posters, news releases, events, team profiles, pages and media library as JSON. Its public code
  lives in the github.com/twinstrandbio organization, which holds a single reference-data repository and no client libraries.
  The DuplexSeq Mutagenesis Assay business has since been transferred to Scantox, and Exact Sciences holds an exclusive license
  to the Duplex Sequencing technology.'
url: https://raw.githubusercontent.com/api-evangelist/twinstrand-biosciences/refs/heads/main/apis.yml
x-type: company
x-source: harvest:secondary-market
x-tier: profiled
x-tier-reason: enrichment-pipeline
image: https://twinstrandbio.com/wp-content/uploads/2023/05/TwinStrand-Favicon-1-300x300.png
specificationVersion: '0.20'
created: '2026-08-05'
modified: '2026-08-05'
tags:
- Company
- Genomics
- Biotechnology
- Life Sciences
- DNA Sequencing
- Next Generation Sequencing
- Oncology
- Genetic Toxicology
- Diagnostics
- Bioinformatics
- Research
- Content
apis:
- aid: twinstrand-biosciences:twinstrand-biosciences-discovery-api
  name: TwinStrand Biosciences Discovery API
  description: The Discovery API from TwinStrand Biosciences — 5 operation(s) for discovery.
  humanURL: https://twinstrandbio.com/publications/
  baseURL: https://twinstrandbio.com/wp-json/wp/v2
  tags:
  - Discovery
  properties:
  - type: OpenAPI
    url: openapi/twinstrand-biosciences-discovery-api-openapi.yml
  - type: DataModel
    url: data-model/twinstrand-biosciences-data-model.yml
  - type: ErrorCatalog
    url: errors/twinstrand-biosciences-problem-types.yml
  - type: Examples
    url: examples/twinstrand-biosciences-examples.yml
- aid: twinstrand-biosciences:twinstrand-biosciences-events-api
  name: TwinStrand Biosciences Events API
  description: The Events API from TwinStrand Biosciences — 2 operation(s) for events.
  humanURL: https://twinstrandbio.com/publications/
  baseURL: https://twinstrandbio.com/wp-json/wp/v2
  tags:
  - Events
  properties:
  - type: OpenAPI
    url: openapi/twinstrand-biosciences-events-api-openapi.yml
  - type: DataModel
    url: data-model/twinstrand-biosciences-data-model.yml
  - type: ErrorCatalog
    url: errors/twinstrand-biosciences-problem-types.yml
  - type: Examples
    url: examples/twinstrand-biosciences-examples.yml
- aid: twinstrand-biosciences:twinstrand-biosciences-media-api
  name: TwinStrand Biosciences Media API
  description: The Media API from TwinStrand Biosciences — 2 operation(s) for media.
  humanURL: https://twinstrandbio.com/publications/
  baseURL: https://twinstrandbio.com/wp-json/wp/v2
  tags:
  - Media
  properties:
  - type: OpenAPI
    url: openapi/twinstrand-biosciences-media-api-openapi.yml
  - type: DataModel
    url: data-model/twinstrand-biosciences-data-model.yml
  - type: ErrorCatalog
    url: errors/twinstrand-biosciences-problem-types.yml
  - type: Examples
    url: examples/twinstrand-biosciences-examples.yml
- aid: twinstrand-biosciences:twinstrand-biosciences-news-api
  name: TwinStrand Biosciences News API
  description: The News API from TwinStrand Biosciences — 2 operation(s) for news.
  humanURL: https://twinstrandbio.com/publications/
  baseURL: https://twinstrandbio.com/wp-json/wp/v2
  tags:
  - News
  properties:
  - type: OpenAPI
    url: openapi/twinstrand-biosciences-news-api-openapi.yml
  - type: DataModel
    url: data-model/twinstrand-biosciences-data-model.yml
  - type: ErrorCatalog
    url: errors/twinstrand-biosciences-problem-types.yml
  - type: Examples
    url: examples/twinstrand-biosciences-examples.yml
- aid: twinstrand-biosciences:twinstrand-biosciences-pages-api
  name: TwinStrand Biosciences Pages API
  description: The Pages API from TwinStrand Biosciences — 2 operation(s) for pages.
  humanURL: https://twinstrandbio.com/publications/
  baseURL: https://twinstrandbio.com/wp-json/wp/v2
  tags:
  - Pages
  properties:
  - type: OpenAPI
    url: openapi/twinstrand-biosciences-pages-api-openapi.yml
  - type: DataModel
    url: data-model/twinstrand-biosciences-data-model.yml
  - type: ErrorCatalog
    url: errors/twinstrand-biosciences-problem-types.yml
  - type: Examples
    url: examples/twinstrand-biosciences-examples.yml
- aid: twinstrand-biosciences:twinstrand-biosciences-patents-api
  name: TwinStrand Biosciences Patents API
  description: The Patents API from TwinStrand Biosciences — 2 operation(s) for patents.
  humanURL: https://twinstrandbio.com/publications/
  baseURL: https://twinstrandbio.com/wp-json/wp/v2
  tags:
  - Patents
  properties:
  - type: OpenAPI
    url: openapi/twinstrand-biosciences-patents-api-openapi.yml
  - type: DataModel
    url: data-model/twinstrand-biosciences-data-model.yml
  - type: ErrorCatalog
    url: errors/twinstrand-biosciences-problem-types.yml
  - type: Examples
    url: examples/twinstrand-biosciences-examples.yml
- aid: twinstrand-biosciences:twinstrand-biosciences-people-api
  name: TwinStrand Biosciences People API
  description: The People API from TwinStrand Biosciences — 4 operation(s) for people.
  humanURL: https://twinstrandbio.com/publications/
  baseURL: https://twinstrandbio.com/wp-json/wp/v2
  tags:
  - People
  properties:
  - type: OpenAPI
    url: openapi/twinstrand-biosciences-people-api-openapi.yml
  - type: DataModel
    url: data-model/twinstrand-biosciences-data-model.yml
  - type: ErrorCatalog
    url: errors/twinstrand-biosciences-problem-types.yml
  - type: Examples
    url: examples/twinstrand-biosciences-examples.yml
- aid: twinstrand-biosciences:twinstrand-biosciences-posters-api
  name: TwinStrand Biosciences Posters API
  description: The Posters API from TwinStrand Biosciences — 2 operation(s) for posters.
  humanURL: https://twinstrandbio.com/publications/
  baseURL: https://twinstrandbio.com/wp-json/wp/v2
  tags:
  - Posters
  properties:
  - type: OpenAPI
    url: openapi/twinstrand-biosciences-posters-api-openapi.yml
  - type: DataModel
    url: data-model/twinstrand-biosciences-data-model.yml
  - type: ErrorCatalog
    url: errors/twinstrand-biosciences-problem-types.yml
  - type: Examples
    url: examples/twinstrand-biosciences-examples.yml
- aid: twinstrand-biosciences:twinstrand-biosciences-posts-api
  name: TwinStrand Biosciences Posts API
  description: The Posts API from TwinStrand Biosciences — 2 operation(s) for posts.
  humanURL: https://twinstrandbio.com/publications/
  baseURL: https://twinstrandbio.com/wp-json/wp/v2
  tags:
  - Posts
  properties:
  - type: OpenAPI
    url: openapi/twinstrand-biosciences-posts-api-openapi.yml
  - type: DataModel
    url: data-model/twinstrand-biosciences-data-model.yml
  - type: ErrorCatalog
    url: errors/twinstrand-biosciences-problem-types.yml
  - type: Examples
    url: examples/twinstrand-biosciences-examples.yml
- aid: twinstrand-biosciences:twinstrand-biosciences-publications-api
  name: TwinStrand Biosciences Publications API
  description: The Publications API from TwinStrand Biosciences — 6 operation(s) for publications.
  humanURL: https://twinstrandbio.com/publications/
  baseURL: https://twinstrandbio.com/wp-json/wp/v2
  tags:
  - Publications
  properties:
  - type: OpenAPI
    url: openapi/twinstrand-biosciences-publications-api-openapi.yml
  - type: DataModel
    url: data-model/twinstrand-biosciences-data-model.yml
  - type: ErrorCatalog
    url: errors/twinstrand-biosciences-problem-types.yml
  - type: Examples
    url: examples/twinstrand-biosciences-examples.yml
- aid: twinstrand-biosciences:twinstrand-biosciences-search-api
  name: TwinStrand Biosciences Search API
  description: The Search API from TwinStrand Biosciences — 1 operation(s) for search.
  humanURL: https://twinstrandbio.com/publications/
  baseURL: https://twinstrandbio.com/wp-json/wp/v2
  tags:
  - Search
  properties:
  - type: OpenAPI
    url: openapi/twinstrand-biosciences-search-api-openapi.yml
  - type: DataModel
    url: data-model/twinstrand-biosciences-data-model.yml
  - type: ErrorCatalog
    url: errors/twinstrand-biosciences-problem-types.yml
  - type: Examples
    url: examples/twinstrand-biosciences-examples.yml
- aid: twinstrand-biosciences:twinstrand-biosciences-taxonomies-api
  name: TwinStrand Biosciences Taxonomies API
  description: The Taxonomies API from TwinStrand Biosciences — 4 operation(s) for taxonomies.
  humanURL: https://twinstrandbio.com/publications/
  baseURL: https://twinstrandbio.com/wp-json/wp/v2
  tags:
  - Taxonomies
  properties:
  - type: OpenAPI
    url: openapi/twinstrand-biosciences-taxonomies-api-openapi.yml
  - type: DataModel
    url: data-model/twinstrand-biosciences-data-model.yml
  - type: ErrorCatalog
    url: errors/twinstrand-biosciences-problem-types.yml
  - type: Examples
    url: examples/twinstrand-biosciences-examples.yml
x-enrichment:
  date: '2026-08-05'
  status: enriched
  artifacts_added: 18
  pass: local-v1
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: Overlay
  url: overlays/twinstrand-biosciences-content-overlay.yaml
- type: Website
  url: https://twinstrandbio.com/
- type: About
  url: https://twinstrandbio.com/company/
- type: Team
  url: https://twinstrandbio.com/company/our-team/
- type: News
  url: https://twinstrandbio.com/company/news/
- type: Technology
  url: https://twinstrandbio.com/technology/
- type: Publications
  url: https://twinstrandbio.com/publications/
- type: Resources
  url: https://twinstrandbio.com/resources/
- type: Investors
  url: https://twinstrandbio.com/company/investors/
- type: Patents
  url: https://twinstrandbio.com/legal/patents/
- type: TermsOfService
  url: https://twinstrandbio.com/legal/product-and-services-terms-and-conditions/
- type: PrivacyPolicy
  url: https://twinstrandbio.com/legal/privacy-policy/
- type: Legal
  url: https://twinstrandbio.com/legal/
- type: GitHubOrganization
  url: https://github.com/twinstrandbio
- type: YouTube
  url: https://www.youtube.com/channel/UCBXpy6SSpg-Mja--uU_mlag
- type: SecondaryMarket
  url: https://forgeglobal.com/twinstrand-biosciences_stock/
- type: Packages
  url: packages/twinstrand-biosciences-packages.yml
- type: LLMsTxt
  url: llms/twinstrand-biosciences-llms.txt
- type: WellKnown
  url: well-known/twinstrand-biosciences-well-known.yml
- type: Authentication
  url: authentication/twinstrand-biosciences-authentication.yml
- type: Conventions
  url: conventions/twinstrand-biosciences-conventions.yml
- type: Conformance
  url: conformance/twinstrand-biosciences-conformance.yml
- type: Lifecycle
  url: lifecycle/twinstrand-biosciences-lifecycle.yml
- type: DomainSecurity
  url: security/twinstrand-biosciences-domain-security.yml
- type: AgentSkill
  url: skills/_index.yml