TwinStrand Biosciences

TwinStrand Biosciences is a Seattle, Washington genomics company founded in 2015 by Jesse Salk and Michael Schmitt that develops and commercializes Duplex Sequencing, an error-corrected next-generation-sequencing chemistry licensed from the University of Washington that independently tracks both strands of an individual DNA molecule and compares them, cutting sequencing error rates from roughly 1-in-100 to below 1-in-10,000,000 per nucleotide and making ultra-rare mutations detectable. The company sells DuplexSeq assay kits — a Mutagenesis Assay for genetic toxicology in human, rat and mouse models, an AML MRD Assay for minimal residual disease in acute myeloid leukemia, and a customizable assay — each paired with a proprietary cloud analysis pipeline that turns raw Illumina reads into duplex-consensus sequences, variant calls, mutation frequency, SBS spectra and assay quality metrics. That analysis software is not a public API: it is hosted on the DNAnexus platform and reachable only by customers through a DNAnexus project. TwinStrand publishes no developer portal, no API reference and no OpenAPI, AsyncAPI, GraphQL or Postman artifact of its own, and the api., docs. and developer. subdomains of twinstrandbio.com do not resolve. The only machine-readable surface on twinstrandbio.com is the WordPress REST API at /wp-json — 349 routes across 18 namespaces — whose wp/v2 content collections are anonymously readable and serve the company publication index, patent estate, conference posters, news releases, events, team profiles, pages and media library as JSON. Its public code lives in the github.com/twinstrandbio organization, which holds a single reference-data repository and no client libraries. The DuplexSeq Mutagenesis Assay business has since been transferred to Scantox, and Exact Sciences holds an exclusive license to the Duplex Sequencing technology.

TwinStrand Biosciences publishes 12 APIs on the APIs.io network, including Discovery API, Events API, Media API, and 9 more. Tagged areas include Company, Genomics, Biotechnology, Life Sciences, and DNA Sequencing.

TwinStrand Biosciences’ developer surface includes product news, legal docs, YouTube channel, authentication, and 21 more developer resources.

🌐 Visit website 📡 Source on GitHub

20.8/100 emerging ▬ flat Agent 24/100 agent aware saas Full breakdown ↓
scored 2026-09-03 · rubric v0.18.2

AccessSelf serve

1 APIs

Company Genomics Biotechnology Life Sciences DNA Sequencing Next-Generation Sequencing OncologyGenetic ToxicologyDiagnostics Bioinformatics Research Content

Kin Score

Kin Score How this is scored →
scored 2026-09-03 · rubric v0.18.2

Composite quality — 20.8/100 · emerging

Contract Quality 3.5 / 21

Developer Ergonomics 2.3 / 17

Access Clarity 3.6 / 17

Operational Transparency 0.3 / 11

Contract Governance 0.5 / 10

Discoverability 5.8 / 9

Regulatory Posture 4.7 / 15

Agent readiness — 24/100 · agent aware

Machine-Readable Contract 18 / 18

Agentic Access Contract 0 / 10

Documented Reversibility 6 / 6

MCP Server 0 / 12

Machine-Readable Auth 10 / 10

Idempotency 9 / 9

Stable Error Semantics 8 / 8

Request/Response Examples 7 / 7

Rate-Limit Signaling 0 / 7

Typed Event Surface 0 / 6

Agent Skills 5 / 5

Well-Known Catalog 0 / 4

Consent & Bot Identity 0 / 3

A2A Agent Card 0 / 8

Dry-Run / Simulate Mode 4 / 4

Delegated User Identity 0 / 6

Protected Resource Metadata 0 / 5

Registration Without a Human 0 / 6

Agentic Commerce Surface 0 / 5

Regulatory Posture applies to this provider. Its tags matched the Health regime, so Regulatory Posture carries 15 points of the composite. If this regime is wrong for your business, say so on your provider repo — the applicability map is public and we will correct it.

The six quality facets above are damped to 85 points between them, because the conditional facet above carries the other 15. That is why each facet's contribution is shown against a damped maximum: raising a quality facet moves the composite by 85% of its nominal weight, not 100%. The full arithmetic is at apis.io/rating/.

Improve this rating by publishing the missing artifacts — every area above can be raised, and the full rubric is at apis.io/rating/. Every facet and dimension name above is a link: it opens that measurement's own page — what it means, the exact checks that feed it, how the whole catalog distributes on it, and the providers at the top of it. This rating is computed from github.com/api-evangelist/twinstrand-biosciences: open an issue to ask a question, or submit a pull request to add artifacts. Submit an artifact on GitHub — free → Manage your own listing — the Influence plan, $499/mo →

Something on this page wrong about TwinStrand Biosciences? Report it → Free, always, and read by a human — corrections are worked from the queue daily. Agents can file the same report through the report_correction tool on the apis.io MCP.

APIs 12

Individual APIs this provider publishes, each with its own machine-readable definition.

Open Collections 13

Open, tool-agnostic API collections (OpenAPI-derived and Bruno).

Agent Surfaces 3

MCP servers, agent skills, and machine-readable catalogs

LLMsTxt

LLMsTxt

WellKnown

WellKnown

AgentSkill

AgentSkill

Design & Contract 3

Pagination, idempotency, versioning, errors, and events

Conventions

Conventions

Conformance

Conformance

Lifecycle

Lifecycle

Build 2

SDKs, sample code, and the tooling you integrate with

GitHubOrganization

GitHubOrganization

Packages

Packages

Access & Security 2

Authentication, authorization, and security posture

Authentication

Authentication

DomainSecurity

DomainSecurity

Learn 1

Tutorials, courses, talks, and written guidance

YouTube

YouTube

Commercial 3

Pricing, plans, and the legal terms of use

TermsOfService

TermsOfService

PrivacyPolicy

PrivacyPolicy

Legal

Legal

Company 4

The organization behind the API

Website

About

News

Investors

Other 7

Properties that don't map to a standard resource type

Overlay

Team

Technology

Publications

Resources

Patents

SecondaryMarket

Scroll for all 7

Source (apis.yml)

aid: twinstrand-biosciences
name: TwinStrand Biosciences
description: 'TwinStrand Biosciences is a Seattle, Washington genomics company founded in 2015 by Jesse Salk and Michael Schmitt
  that develops and commercializes Duplex Sequencing, an error-corrected next-generation-sequencing chemistry licensed from
  the University of Washington that independently tracks both strands of an individual DNA molecule and compares them, cutting
  sequencing error rates from roughly 1-in-100 to below 1-in-10,000,000 per nucleotide and making ultra-rare mutations detectable.
  The company sells DuplexSeq assay kits — a Mutagenesis Assay for genetic toxicology in human, rat and mouse models, an AML
  MRD Assay for minimal residual disease in acute myeloid leukemia, and a customizable assay — each paired with a proprietary
  cloud analysis pipeline that turns raw Illumina reads into duplex-consensus sequences, variant calls, mutation frequency,
  SBS spectra and assay quality metrics. That analysis software is not a public API: it is hosted on the DNAnexus platform
  and reachable only by customers through a DNAnexus project. TwinStrand publishes no developer portal, no API reference and
  no OpenAPI, AsyncAPI, GraphQL or Postman artifact of its own, and the api., docs. and developer. subdomains of twinstrandbio.com
  do not resolve. The only machine-readable surface on twinstrandbio.com is the WordPress REST API at /wp-json — 349 routes
  across 18 namespaces — whose wp/v2 content collections are anonymously readable and serve the company publication index,
  patent estate, conference posters, news releases, events, team profiles, pages and media library as JSON. Its public code
  lives in the github.com/twinstrandbio organization, which holds a single reference-data repository and no client libraries.
  The DuplexSeq Mutagenesis Assay business has since been transferred to Scantox, and Exact Sciences holds an exclusive license
  to the Duplex Sequencing technology.'
url: https://raw.githubusercontent.com/api-evangelist/twinstrand-biosciences/refs/heads/main/apis.yml
x-type: company
x-source: harvest:secondary-market
x-tier: profiled
x-tier-reason: enrichment-pipeline
deliveryModel:
  model: saas
  open_source: false
  commercial: true
  callable_host: true
  label: Hosted service · you call their endpoint
  confidence: high
  source:
  - openapi
  - pricing
  generated: '2026-08-28'
  method: derived
accessModel:
  pricing: unknown
  onboarding: self-serve
  trial: false
  try_now: false
  public: false
  label: Self-serve signup
  confidence: low
  source:
  - authentication
  - security
  generated: '2026-09-02'
  method: derived
image: https://twinstrandbio.com/wp-content/uploads/2023/05/TwinStrand-Favicon-1-300x300.png
specificationVersion: '0.23'
created: '2026-08-05'
modified: '2026-08-05'
tags:
- Company
- Genomics
- Biotechnology
- Life Sciences
- DNA Sequencing
- Next-Generation Sequencing
- Oncology
- Genetic Toxicology
- Diagnostics
- Bioinformatics
- Research
- Content
tags_raw:
- Company
- Genomics
- Biotechnology
- Life Sciences
- DNA Sequencing
- Next Generation Sequencing
- Oncology
- Genetic Toxicology
- Diagnostics
- Bioinformatics
- Research
- Content
apis:
- aid: twinstrand-biosciences:twinstrand-biosciences-discovery-api
  name: TwinStrand Biosciences Discovery API
  description: The Discovery API from TwinStrand Biosciences — 5 operation(s) for discovery.
  humanURL: https://twinstrandbio.com/publications/
  baseURL: https://twinstrandbio.com/wp-json/wp/v2
  tags:
  - Discovery
  properties:
  - type: OpenAPI
    url: openapi/twinstrand-biosciences-discovery-api-openapi.yml
  - type: DataModel
    url: data-model/twinstrand-biosciences-data-model.yml
  - type: ErrorCatalog
    url: errors/twinstrand-biosciences-problem-types.yml
  - type: Examples
    url: examples/twinstrand-biosciences-examples.yml
- aid: twinstrand-biosciences:twinstrand-biosciences-events-api
  name: TwinStrand Biosciences Events API
  description: The Events API from TwinStrand Biosciences — 2 operation(s) for events.
  humanURL: https://twinstrandbio.com/publications/
  baseURL: https://twinstrandbio.com/wp-json/wp/v2
  tags:
  - Event
  tags_raw:
  - Events
  properties:
  - type: OpenAPI
    url: openapi/twinstrand-biosciences-events-api-openapi.yml
  - type: DataModel
    url: data-model/twinstrand-biosciences-data-model.yml
  - type: ErrorCatalog
    url: errors/twinstrand-biosciences-problem-types.yml
  - type: Examples
    url: examples/twinstrand-biosciences-examples.yml
- aid: twinstrand-biosciences:twinstrand-biosciences-media-api
  name: TwinStrand Biosciences Media API
  description: The Media API from TwinStrand Biosciences — 2 operation(s) for media.
  humanURL: https://twinstrandbio.com/publications/
  baseURL: https://twinstrandbio.com/wp-json/wp/v2
  tags:
  - Media
  properties:
  - type: OpenAPI
    url: openapi/twinstrand-biosciences-media-api-openapi.yml
  - type: DataModel
    url: data-model/twinstrand-biosciences-data-model.yml
  - type: ErrorCatalog
    url: errors/twinstrand-biosciences-problem-types.yml
  - type: Examples
    url: examples/twinstrand-biosciences-examples.yml
- aid: twinstrand-biosciences:twinstrand-biosciences-news-api
  name: TwinStrand Biosciences News API
  description: The News API from TwinStrand Biosciences — 2 operation(s) for news.
  humanURL: https://twinstrandbio.com/publications/
  baseURL: https://twinstrandbio.com/wp-json/wp/v2
  tags:
  - News
  properties:
  - type: OpenAPI
    url: openapi/twinstrand-biosciences-news-api-openapi.yml
  - type: DataModel
    url: data-model/twinstrand-biosciences-data-model.yml
  - type: ErrorCatalog
    url: errors/twinstrand-biosciences-problem-types.yml
  - type: Examples
    url: examples/twinstrand-biosciences-examples.yml
- aid: twinstrand-biosciences:twinstrand-biosciences-pages-api
  name: TwinStrand Biosciences Pages API
  description: The Pages API from TwinStrand Biosciences — 2 operation(s) for pages.
  humanURL: https://twinstrandbio.com/publications/
  baseURL: https://twinstrandbio.com/wp-json/wp/v2
  tags:
  - Pages
  properties:
  - type: OpenAPI
    url: openapi/twinstrand-biosciences-pages-api-openapi.yml
  - type: DataModel
    url: data-model/twinstrand-biosciences-data-model.yml
  - type: ErrorCatalog
    url: errors/twinstrand-biosciences-problem-types.yml
  - type: Examples
    url: examples/twinstrand-biosciences-examples.yml
- aid: twinstrand-biosciences:twinstrand-biosciences-patents-api
  name: TwinStrand Biosciences Patents API
  description: The Patents API from TwinStrand Biosciences — 2 operation(s) for patents.
  humanURL: https://twinstrandbio.com/publications/
  baseURL: https://twinstrandbio.com/wp-json/wp/v2
  tags:
  - Patents
  properties:
  - type: OpenAPI
    url: openapi/twinstrand-biosciences-patents-api-openapi.yml
  - type: DataModel
    url: data-model/twinstrand-biosciences-data-model.yml
  - type: ErrorCatalog
    url: errors/twinstrand-biosciences-problem-types.yml
  - type: Examples
    url: examples/twinstrand-biosciences-examples.yml
- aid: twinstrand-biosciences:twinstrand-biosciences-people-api
  name: TwinStrand Biosciences People API
  description: The People API from TwinStrand Biosciences — 4 operation(s) for people.
  humanURL: https://twinstrandbio.com/publications/
  baseURL: https://twinstrandbio.com/wp-json/wp/v2
  tags:
  - People
  properties:
  - type: OpenAPI
    url: openapi/twinstrand-biosciences-people-api-openapi.yml
  - type: DataModel
    url: data-model/twinstrand-biosciences-data-model.yml
  - type: ErrorCatalog
    url: errors/twinstrand-biosciences-problem-types.yml
  - type: Examples
    url: examples/twinstrand-biosciences-examples.yml
- aid: twinstrand-biosciences:twinstrand-biosciences-posters-api
  name: TwinStrand Biosciences Posters API
  description: The Posters API from TwinStrand Biosciences — 2 operation(s) for posters.
  humanURL: https://twinstrandbio.com/publications/
  baseURL: https://twinstrandbio.com/wp-json/wp/v2
  tags:
  - Posters
  properties:
  - type: OpenAPI
    url: openapi/twinstrand-biosciences-posters-api-openapi.yml
  - type: DataModel
    url: data-model/twinstrand-biosciences-data-model.yml
  - type: ErrorCatalog
    url: errors/twinstrand-biosciences-problem-types.yml
  - type: Examples
    url: examples/twinstrand-biosciences-examples.yml
- aid: twinstrand-biosciences:twinstrand-biosciences-posts-api
  name: TwinStrand Biosciences Posts API
  description: The Posts API from TwinStrand Biosciences — 2 operation(s) for posts.
  humanURL: https://twinstrandbio.com/publications/
  baseURL: https://twinstrandbio.com/wp-json/wp/v2
  tags:
  - Posts
  properties:
  - type: OpenAPI
    url: openapi/twinstrand-biosciences-posts-api-openapi.yml
  - type: DataModel
    url: data-model/twinstrand-biosciences-data-model.yml
  - type: ErrorCatalog
    url: errors/twinstrand-biosciences-problem-types.yml
  - type: Examples
    url: examples/twinstrand-biosciences-examples.yml
- aid: twinstrand-biosciences:twinstrand-biosciences-publications-api
  name: TwinStrand Biosciences Publications API
  description: The Publications API from TwinStrand Biosciences — 6 operation(s) for publications.
  humanURL: https://twinstrandbio.com/publications/
  baseURL: https://twinstrandbio.com/wp-json/wp/v2
  tags:
  - Publications
  properties:
  - type: OpenAPI
    url: openapi/twinstrand-biosciences-publications-api-openapi.yml
  - type: DataModel
    url: data-model/twinstrand-biosciences-data-model.yml
  - type: ErrorCatalog
    url: errors/twinstrand-biosciences-problem-types.yml
  - type: Examples
    url: examples/twinstrand-biosciences-examples.yml
- aid: twinstrand-biosciences:twinstrand-biosciences-search-api
  name: TwinStrand Biosciences Search API
  description: The Search API from TwinStrand Biosciences — 1 operation(s) for search.
  humanURL: https://twinstrandbio.com/publications/
  baseURL: https://twinstrandbio.com/wp-json/wp/v2
  tags:
  - Search
  properties:
  - type: OpenAPI
    url: openapi/twinstrand-biosciences-search-api-openapi.yml
  - type: DataModel
    url: data-model/twinstrand-biosciences-data-model.yml
  - type: ErrorCatalog
    url: errors/twinstrand-biosciences-problem-types.yml
  - type: Examples
    url: examples/twinstrand-biosciences-examples.yml
- aid: twinstrand-biosciences:twinstrand-biosciences-taxonomies-api
  name: TwinStrand Biosciences Taxonomies API
  description: The Taxonomies API from TwinStrand Biosciences — 4 operation(s) for taxonomies.
  humanURL: https://twinstrandbio.com/publications/
  baseURL: https://twinstrandbio.com/wp-json/wp/v2
  tags:
  - taxonomies
  tags_raw:
  - Taxonomies
  properties:
  - type: OpenAPI
    url: openapi/twinstrand-biosciences-taxonomies-api-openapi.yml
  - type: DataModel
    url: data-model/twinstrand-biosciences-data-model.yml
  - type: ErrorCatalog
    url: errors/twinstrand-biosciences-problem-types.yml
  - type: Examples
    url: examples/twinstrand-biosciences-examples.yml
x-enrichment:
  date: '2026-08-05'
  status: enriched
  artifacts_added: 18
  pass: local-v1
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: Overlay
  url: overlays/twinstrand-biosciences-content-overlay.yaml
- type: Website
  url: https://twinstrandbio.com/
- type: About
  url: https://twinstrandbio.com/company/
- type: Team
  url: https://twinstrandbio.com/company/our-team/
- type: News
  url: https://twinstrandbio.com/company/news/
- type: Technology
  url: https://twinstrandbio.com/technology/
- type: Publications
  url: https://twinstrandbio.com/publications/
- type: Resources
  url: https://twinstrandbio.com/resources/
- type: Investors
  url: https://twinstrandbio.com/company/investors/
- type: Patents
  url: https://twinstrandbio.com/legal/patents/
- type: TermsOfService
  url: https://twinstrandbio.com/legal/product-and-services-terms-and-conditions/
- type: PrivacyPolicy
  url: https://twinstrandbio.com/legal/privacy-policy/
- type: Legal
  url: https://twinstrandbio.com/legal/
- type: GitHubOrganization
  url: https://github.com/twinstrandbio
- type: YouTube
  url: https://www.youtube.com/channel/UCBXpy6SSpg-Mja--uU_mlag
- type: SecondaryMarket
  url: https://forgeglobal.com/twinstrand-biosciences_stock/
- type: Packages
  url: packages/twinstrand-biosciences-packages.yml
- type: LLMsTxt
  url: llms/twinstrand-biosciences-llms.txt
- type: WellKnown
  url: well-known/twinstrand-biosciences-well-known.yml
- type: Authentication
  url: authentication/twinstrand-biosciences-authentication.yml
- type: Conventions
  url: conventions/twinstrand-biosciences-conventions.yml
- type: Conformance
  url: conformance/twinstrand-biosciences-conformance.yml
- type: Lifecycle
  url: lifecycle/twinstrand-biosciences-lifecycle.yml
- type: DomainSecurity
  url: security/twinstrand-biosciences-domain-security.yml
- type: AgentSkill
  url: skills/_index.yml

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