TwinStrand Biosciences

aid: twinstrand-biosciences
name: TwinStrand Biosciences
description: 'TwinStrand Biosciences is a Seattle, Washington genomics company founded in 2015 by Jesse Salk and Michael Schmitt
  that develops and commercializes Duplex Sequencing, an error-corrected next-generation-sequencing chemistry licensed from
  the University of Washington that independently tracks both strands of an individual DNA molecule and compares them, cutting
  sequencing error rates from roughly 1-in-100 to below 1-in-10,000,000 per nucleotide and making ultra-rare mutations detectable.
  The company sells DuplexSeq assay kits — a Mutagenesis Assay for genetic toxicology in human, rat and mouse models, an AML
  MRD Assay for minimal residual disease in acute myeloid leukemia, and a customizable assay — each paired with a proprietary
  cloud analysis pipeline that turns raw Illumina reads into duplex-consensus sequences, variant calls, mutation frequency,
  SBS spectra and assay quality metrics. That analysis software is not a public API: it is hosted on the DNAnexus platform
  and reachable only by customers through a DNAnexus project. TwinStrand publishes no developer portal, no API reference and
  no OpenAPI, AsyncAPI, GraphQL or Postman artifact of its own, and the api., docs. and developer. subdomains of twinstrandbio.com
  do not resolve. The only machine-readable surface on twinstrandbio.com is the WordPress REST API at /wp-json — 349 routes
  across 18 namespaces — whose wp/v2 content collections are anonymously readable and serve the company publication index,
  patent estate, conference posters, news releases, events, team profiles, pages and media library as JSON. Its public code
  lives in the github.com/twinstrandbio organization, which holds a single reference-data repository and no client libraries.
  The DuplexSeq Mutagenesis Assay business has since been transferred to Scantox, and Exact Sciences holds an exclusive license
  to the Duplex Sequencing technology.'
url: https://raw.githubusercontent.com/api-evangelist/twinstrand-biosciences/refs/heads/main/apis.yml
x-type: company
x-source: harvest:secondary-market
x-tier: profiled
x-tier-reason: enrichment-pipeline
deliveryModel:
  model: saas
  open_source: false
  commercial: true
  callable_host: true
  label: Hosted service · you call their endpoint
  confidence: high
  source:
  - openapi
  - pricing
  generated: '2026-08-28'
  method: derived
accessModel:
  pricing: unknown
  onboarding: unknown
  trial: false
  try_now: false
  public: false
  label: Unknown
  confidence: low
  source:
  - authentication
  - security
  generated: '2026-09-03'
  method: derived
image: https://twinstrandbio.com/wp-content/uploads/2023/05/TwinStrand-Favicon-1-300x300.png
specificationVersion: '0.23'
created: '2026-08-05'
modified: '2026-08-05'
tags:
- Company
- Genomics
- Biotechnology
- Life Sciences
- DNA Sequencing
- Next-Generation Sequencing
- Oncology
- Genetic Toxicology
- Diagnostics
- Bioinformatics
- Research
- Content
tags_raw:
- Company
- Genomics
- Biotechnology
- Life Sciences
- DNA Sequencing
- Next Generation Sequencing
- Oncology
- Genetic Toxicology
- Diagnostics
- Bioinformatics
- Research
- Content
apis:
- aid: twinstrand-biosciences:twinstrandbio-com-website-wordpress-rest
  name: TwinStrand Biosciences Website (WordPress REST)
  description: 'The public WordPress REST API (wp-json) of the TwinStrand Biosciences website at twinstrandbio.com: the route
    index of the site''s content management system, catalogued as one site surface rather than as separate APIs.'
  baseURL: https://twinstrandbio.com/wp-json
  tags:
  - WordPress
  x-surface: platform-generated
  properties:
  - type: Documentation
    url: https://twinstrandbio.com/wp-json
  x-platform: wordpress
  x-platform-surface: rest
x-enrichment:
  date: '2026-08-05'
  status: enriched
  artifacts_added: 18
  pass: local-v1
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: Overlay
  url: overlays/twinstrand-biosciences-content-overlay.yaml
- type: Website
  url: https://twinstrandbio.com/
- type: About
  url: https://twinstrandbio.com/company/
- type: Team
  url: https://twinstrandbio.com/company/our-team/
- type: News
  url: https://twinstrandbio.com/company/news/
- type: Technology
  url: https://twinstrandbio.com/technology/
- type: Publications
  url: https://twinstrandbio.com/publications/
- type: Resources
  url: https://twinstrandbio.com/resources/
- type: Investors
  url: https://twinstrandbio.com/company/investors/
- type: Patents
  url: https://twinstrandbio.com/legal/patents/
- type: TermsOfService
  url: https://twinstrandbio.com/legal/product-and-services-terms-and-conditions/
- type: PrivacyPolicy
  url: https://twinstrandbio.com/legal/privacy-policy/
- type: Legal
  url: https://twinstrandbio.com/legal/
- type: GitHubOrganization
  url: https://github.com/twinstrandbio
- type: YouTube
  url: https://www.youtube.com/channel/UCBXpy6SSpg-Mja--uU_mlag
- type: SecondaryMarket
  url: https://forgeglobal.com/twinstrand-biosciences_stock/
- type: Packages
  url: packages/twinstrand-biosciences-packages.yml
- type: LLMsTxt
  url: llms/twinstrand-biosciences-llms.txt
- type: WellKnown
  url: well-known/twinstrand-biosciences-well-known.yml
- type: Authentication
  url: authentication/twinstrand-biosciences-authentication.yml
- type: Conventions
  url: conventions/twinstrand-biosciences-conventions.yml
- type: Conformance
  url: conformance/twinstrand-biosciences-conformance.yml
- type: Lifecycle
  url: lifecycle/twinstrand-biosciences-lifecycle.yml
- type: DomainSecurity
  url: security/twinstrand-biosciences-domain-security.yml
- type: AgentSkill
  url: skills/_index.yml
- type: DataModel
  url: data-model/twinstrand-biosciences-data-model.yml
- type: ErrorCatalog
  url: errors/twinstrand-biosciences-problem-types.yml