Topos Bio

Topos Bio is an AI-native drug discovery company building all-atom foundation models for intrinsically disordered proteins (IDPs) — dynamic, flexible proteins implicated in diseases such as Alzheimer's and prostate cancer. Its Topos-1 foundation model generates physically realistic conformational ensembles for flexible proteins, aiming to make previously undruggable targets therapeutically viable. The company is backed by Threshold Ventures. No public API or developer platform is currently published.

Topos Bio is profiled on the APIs.io network. Tagged areas include Company, Healthcare, Drug Discovery, Artificial Intelligence, and Biotech.

10.8/100 minimal ▬ flat Agent 0/100 human only Full breakdown ↓
scored 2026-07-27 · rubric v0.5
0 APIs
CompanyHealthcareDrug DiscoveryArtificial IntelligenceBiotechFoundation ModelsComputational BiologyProteinsLife Sciences

Kin Score

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scored 2026-07-27 · rubric v0.5
Composite quality — 10.8/100 · minimal
Contract Quality 0.0 / 25
Developer Ergonomics 0.0 / 20
Commercial Clarity 2.1 / 20
Operational Transparency 0.0 / 13
Governance 0.0 / 12
Discoverability 6.8 / 10
Agent readiness — 0/100 · human only
Machine-Readable Contract 0 / 18
Agentic Access Contract 0 / 15
MCP Server 0 / 12
Machine-Readable Auth 0 / 10
Idempotency 0 / 9
Stable Error Semantics 0 / 8
Request/Response Examples 0 / 7
Rate-Limit Signaling 0 / 7
Typed Event Surface 0 / 6
Agent Skills 0 / 5
Well-Known Catalog 0 / 4
Consent & Bot Identity 0 / 3
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Security Posture 1

Authentication, domain security, vulnerability disclosure, and trust-center signals.

Topos Bio Domain Security

TLSv1.3 · HSTS · DMARC

SECURITY

Resources

Access & Security 1

Authentication, authorization, and security posture

Commercial 1

Pricing, plans, and the legal terms of use

Company 4

The organization behind the API

Other 1

Properties that don't map to a standard resource type

Source (apis.yml)

apis.yml Raw ↑
aid: topos-bio
accessModel:
  pricing: unknown
  onboarding: unknown
  trial: false
  try_now: false
  public: false
  label: Unknown
  confidence: low
  source: []
  generated: '2026-07-22'
  method: derived
image: https://kinlane-images.s3.amazonaws.com/shared/apis-json/icons/topos-bio.png
name: Topos Bio
description: Topos Bio is an AI-native drug discovery company building all-atom foundation models for intrinsically disordered
  proteins (IDPs) — dynamic, flexible proteins implicated in diseases such as Alzheimer's and prostate cancer. Its Topos-1
  foundation model generates physically realistic conformational ensembles for flexible proteins, aiming to make previously
  undruggable targets therapeutically viable. The company is backed by Threshold Ventures. No public API or developer platform
  is currently published.
url: https://raw.githubusercontent.com/api-evangelist/topos-bio/refs/heads/main/apis.yml
x-type: company
x-source: vc-portfolio
x-backed-by:
- threshold-ventures
x-tier: stub
x-tier-reason: portfolio-lead
specificationVersion: '0.20'
created: '2026-07-17'
modified: '2026-07-21'
tags:
- Company
- Healthcare
- Drug Discovery
- Artificial Intelligence
- Biotech
- Foundation Models
- Computational Biology
- Proteins
- Life Sciences
apis: []
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: DomainSecurity
  url: security/topos-bio-domain-security.yml
- type: Website
  url: https://www.toposbio.ai/
- type: About
  url: https://www.toposbio.ai/about
- type: PrivacyPolicy
  url: https://www.toposbio.ai/privacy
- type: TechnicalReport
  url: https://www.toposbio.ai/Topos_1_Technical_Report.pdf
- type: Press
  url: https://www.toposbio.ai/press
- type: Careers
  url: https://jobs.ashbyhq.com/toposbio
x-enrichment:
  date: '2026-07-21'
  status: minimal
  artifacts_added: 1
  pass: local-v1