Sherlock Biosciences

Sherlock Biosciences is a molecular diagnostics company founded in 2019 out of the Broad Institute to commercialize SHERLOCK (Specific High-sensitivity Enzymatic Reporter unLOCKing), the CRISPR-based nucleic-acid detection method developed in the Zhang lab, alongside INSPECTR, an ambient-temperature synthetic-biology amplification platform. In May 2020 it received the first FDA Emergency Use Authorization ever granted to a CRISPR-based diagnostic, for SARS-CoV-2. The company developed disposable, instrument-free molecular self-tests, led by a combined Chlamydia trachomatis and Neisseria gonorrhoeae assay. OraSure Technologies acquired Sherlock Biosciences in December 2024 and absorbed it into its rapid-diagnostics portfolio; the sherlock.bio domain now permanently redirects to orasure.com. Sherlock Biosciences is a laboratory diagnostics developer and has never operated a public developer program, HTTP API, or machine-readable API contract.

Sherlock Biosciences is profiled on the APIs.io network. Tagged areas include Diagnostics, Molecular Diagnostics, CRISPR, Biotechnology, and Life Sciences.

🌐 Visit website 📡 Source on GitHub

4.4/100 minimal ▬ flat Agent 0/100 human only library Full breakdown ↓
scored 2026-09-25 · rubric v0.23.0

0 APIs

Diagnostics Molecular Diagnostics CRISPR Biotechnology Life Sciences Healthcare Infectious Disease Point of Care Testing Synthetic Biology Bioinformatics Acquired

Kin Score

Kin Score How this is scored →
scored 2026-09-25 · rubric v0.23.0

Composite quality — 4.4/100 · minimal

Contract Quality 0.0 / 21

Developer Ergonomics 0.0 / 17

Access Clarity 0.0 / 17

Operational Transparency 0.3 / 11

Contract Governance 0.0 / 10

Discoverability 4.4 / 9

Regulatory Posture 0.7 / 15

Agent readiness — 0/100 · human only

Machine-Readable Contract 0 / 18

Agentic Access Contract 0 / 10

Documented Reversibility 0 / 6

MCP Server 0 / 12

Machine-Readable Auth 0 / 10

Idempotency 0 / 9

Stable Error Semantics 0 / 8

Request/Response Examples 0 / 7

Rate-Limit Signaling 0 / 7

Typed Event Surface 0 / 6

Agent Skills 0 / 5

Well-Known Catalog 0 / 4

Consent & Bot Identity 0 / 3

A2A Agent Card 0 / 8

Dry-Run / Simulate Mode 0 / 4

Delegated User Identity 0 / 6

Protected Resource Metadata 0 / 5

Registration Without a Human 0 / 6

Agentic Commerce Well-Known Document 0 / 5

Regulatory Posture applies to this provider. Its tags matched the Health regime, so Regulatory Posture carries 15 points of the composite. If this regime is wrong for your business, say so on your provider repo — the applicability map is public and we will correct it.

Create-or-Update Ergonomics could not be measured. We hold no machine-readable contract for this provider to read, so there is nothing to measure a write surface against. Excluded rather than scored zero: never-measured and measured-empty are different facts. Publishing an OpenAPI is what makes this facet — and several others — scorable at all.

The six quality facets above are damped to 85 points between them, because the conditional facet above carries the other 15. That is why each facet's contribution is shown against a damped maximum: raising a quality facet moves the composite by 85% of its nominal weight, not 100%. The full arithmetic is at apis.io/rating/.

Improve this rating by publishing the missing artifacts — every area above can be raised, and the full rubric is at apis.io/rating/. Every facet and dimension name above is a link: it opens that measurement's own page — what it means, the exact checks that feed it, how the whole catalog distributes on it, and the providers at the top of it. This rating is computed from github.com/api-evangelist/sherlock-biosciences: open an issue to ask a question, or submit a pull request to add artifacts. Submit an artifact on GitHub — free → Manage your own listing — the Influence plan, $499/mo →

Security Posture 1

Authentication, domain security, vulnerability disclosure, and trust-center signals.

Sherlock Biosciences Domain Security

TLSv1.3 · DMARC

SECURITY

Resources

Agent Surfaces 1

MCP servers, agent skills, and machine-readable catalogs

LLMsTxt

LLMsTxt

Build 2

SDKs, sample code, and the tooling you integrate with

GitHubOrganization

GitHubOrganization

Packages

Packages

Access & Security 1

Authentication, authorization, and security posture

DomainSecurity

DomainSecurity

Company 1

The organization behind the API

Website

Website

Other 1

Properties that don't map to a standard resource type

ParentCompany

ParentCompany

Source (apis.yml)

aid: sherlock-biosciences
name: Sherlock Biosciences
description: Sherlock Biosciences is a molecular diagnostics company founded in 2019 out of the Broad Institute to commercialize
  SHERLOCK (Specific High-sensitivity Enzymatic Reporter unLOCKing), the CRISPR-based nucleic-acid detection method developed
  in the Zhang lab, alongside INSPECTR, an ambient-temperature synthetic-biology amplification platform. In May 2020 it received
  the first FDA Emergency Use Authorization ever granted to a CRISPR-based diagnostic, for SARS-CoV-2. The company developed
  disposable, instrument-free molecular self-tests, led by a combined Chlamydia trachomatis and Neisseria gonorrhoeae assay.
  OraSure Technologies acquired Sherlock Biosciences in December 2024 and absorbed it into its rapid-diagnostics portfolio;
  the sherlock.bio domain now permanently redirects to orasure.com. Sherlock Biosciences is a laboratory diagnostics developer
  and has never operated a public developer program, HTTP API, or machine-readable API contract.
url: https://raw.githubusercontent.com/api-evangelist/sherlock-biosciences/refs/heads/main/apis.yml
x-type: company
x-source: harvest:secondary-market
deliveryModel:
  model: library
  open_source: false
  commercial: false
  callable_host: false
  label: Library · distributed through package registries, no callable service
  confidence: low
  source:
  - none
  generated: '2026-08-28'
  method: derived
accessModel:
  pricing: unknown
  onboarding: unknown
  trial: false
  try_now: false
  public: false
  label: Unknown
  confidence: low
  source:
  - security
  - url: https://sherlock.bio/
    status: 301
    note: declared website redirects to https://orasure.com/ — a different registrable domain (sherlock.bio -> orasure.com),
      possible rename or acquisition (probed 2026-09-03, roadmap#169)
  generated: '2026-09-02'
  method: derived
specificationVersion: '0.20'
created: '2026-08-27'
modified: '2026-08-27'
tags:
- Diagnostics
- Molecular Diagnostics
- CRISPR
- Biotechnology
- Life Sciences
- Healthcare
- Infectious Disease
- Point of Care Testing
- Synthetic Biology
- Bioinformatics
- Acquired
apis: []
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: DomainSecurity
  url: security/sherlock-biosciences-domain-security.yml
- type: Website
  url: https://sherlock.bio/
- type: ParentCompany
  url: https://orasure.com/
- type: GitHubOrganization
  url: https://github.com/SherlockBiosciences
- type: Packages
  url: packages/sherlock-biosciences-packages.yml
- type: LLMsTxt
  url: llms/sherlock-biosciences-llms.txt
x-enrichment:
  date: '2026-08-27'
  status: minimal
  artifacts_added: 4
  pass: local-v1
x-coverage:
  state: none
  reason: defunct
  detail: Sherlock Biosciences was acquired by OraSure Technologies in December 2024 and fully absorbed; its own domain sherlock.bio
    now returns a bare 301 to orasure.com, and every contract-discovery and .well-known path probed on sherlock.bio, orasure.com
    and www.orasure.com returned 404, leaving a molecular-diagnostics company that never ran a developer program with no surviving
    API surface of any kind.
  evidence:
  - url: https://sherlock.bio/
    status: 301
  - url: https://sherlock.bio/openapi.json
    status: 404
  - url: https://sherlock.bio/.well-known/agent-card.json
    status: 404
  - url: https://orasure.com/openapi.json
    status: 404
  - url: https://www.orasure.com/.well-known/api-catalog
    status: 404
  - url: https://github.com/SherlockBiosciences
    status: 200
  checked: '2026-08-27'

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