QurAlis
QurAlis Corporation is a clinical-stage biotechnology company founded on December 12, 2016 in Cambridge, Massachusetts by Drs. Kasper Roet, Kevin Eggan and Clifford Woolf together with Q-State Biosciences, and staffed by neurodegenerative biologists out of Harvard Medical School and Harvard University. The company develops precision medicines for amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD) and other neurodegenerative and neurological diseases, built on the discovery — published in Nature Neuroscience by co-founder Kevin Eggan's lab — that loss of normal TDP-43 function drives a decrease in STATHMIN-2 (STMN2) expression and impairs neuronal repair. Its lead candidates are QRL-201, a first-in-class molecule intended to restore STMN2 expression in ALS (ANQUR trial), and QRL-101, a potentially best-in-class selective Kv7.2/7.3 ion channel opener for hyperexcitability-induced disease progression in ALS as well as epilepsy and pain; a third program targets UNC13A cryptic-exon mis-splicing. Therapies are built on the proprietary FlexASO® anti-sense oligonucleotide splice-modulator platform. QurAlis publishes a corporate site covering its story, pipeline, platform, people, patient resources, presentations and press releases, but runs no developer program: no API documentation, no SDKs, no developer portal, no GitHub organisation and no machine-readable API contract of any kind.
QurAlis is profiled on the APIs.io network. Tagged areas include Company, Biotechnology, Pharmaceuticals, Life Sciences, and Neurology.
QurAlis’ developer surface includes product news, engineering blog, support, and 16 more developer resources.
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Agent Surfaces 2
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