NuProbe

NuProbe is a genomics and molecular diagnostics company founded in 2016 on technology licensed from the Wyss Institute at Harvard University and Rice University, with headquarters in Shanghai, China and a US subsidiary, NuProbe USA, in Houston, Texas. Its two core chemistries are Blocker Displacement Amplification (BDA), which enriches low-frequency DNA variants ahead of sequencing or PCR, and Quantitative Amplicon Sequencing (QASeq), a UMI-based multiplexed amplicon method for the simultaneous ultrasensitive detection of mutations and copy number variations from FFPE tissue, fresh or frozen tissue and cell-free DNA. The company sells research-use assay panels for oncology and reproductive health, custom assay development, and biopharma services, and has licensed or co-developed its chemistry with Bio-Rad, Oxford Nanopore, QIAGEN, Illumina and Bionano. NuProbe is an assay and reagent company: its bioinformatics and primer-design algorithms are delivered inside its products and services rather than as a public developer platform, and it publishes no API, SDK, developer portal or machine-readable specification of any kind.

NuProbe is profiled on the APIs.io network. Tagged areas include Company, Life Sciences, Genomics, Molecular Diagnostics, and Next-Generation Sequencing.

NuProbe’s developer surface includes engineering blog, support, and 4 more developer resources.

🌐 Visit website 📡 Source on GitHub
6.9/100 minimal ▬ flat Agent 0/100 human only saas Full breakdown ↓
scored 2026-09-02 · rubric v0.18.0
0 APIs
CompanyLife SciencesGenomicsMolecular DiagnosticsNext-Generation SequencingOncologyBiotechnologyPrecision MedicineLaboratory

Kin Score

Kin Score Kin Score How this is scored →
scored 2026-09-02 · rubric v0.18.0
Composite quality — 6.9/100 · minimal
Contract Quality 0.0 / 21
Developer Ergonomics 0.6 / 17
Access Clarity 1.8 / 17
Operational Transparency 0.0 / 11
Contract Governance 0.0 / 10
Discoverability 4.3 / 9
Regulatory Posture 1.9 / 15
Agent readiness — 0/100 · human only
Machine-Readable Contract 0 / 18
Agentic Access Contract 0 / 10
Documented Reversibility 0 / 6
MCP Server 0 / 12
Machine-Readable Auth 0 / 10
Idempotency 0 / 9
Stable Error Semantics 0 / 8
Request/Response Examples 0 / 7
Rate-Limit Signaling 0 / 7
Typed Event Surface 0 / 6
Agent Skills 0 / 5
Well-Known Catalog 0 / 4
Consent & Bot Identity 0 / 3
A2A Agent Card 0 / 8
Dry-Run / Simulate Mode 0 / 4
Delegated User Identity 0 / 6
Protected Resource Metadata 0 / 5
Registration Without a Human 0 / 6
Agentic Commerce Surface 0 / 5
Regulatory Posture applies to this provider. Its tags matched the Health regime, so Regulatory Posture carries 15 points of the composite. If this regime is wrong for your business, say so on your provider repo — the applicability map is public and we will correct it.
The six quality facets above are damped to 85 points between them, because the conditional facet above carries the other 15. That is why each facet's contribution is shown against a damped maximum: raising a quality facet moves the composite by 85% of its nominal weight, not 100%. The full arithmetic is at apis.io/rating/.
Improve this rating by publishing the missing artifacts — every area above can be raised, and the full rubric is at apis.io/rating/. Every facet and dimension name above is a link: it opens that measurement's own page — what it means, the exact checks that feed it, how the whole catalog distributes on it, and the providers at the top of it. This rating is computed from github.com/api-evangelist/nuprobe: open an issue to ask a question, or submit a pull request to add artifacts. Submit an artifact on GitHub — free → Manage your own listing — the Influence plan, $499/mo →

Security Posture 1

Authentication, domain security, vulnerability disclosure, and trust-center signals.

Nuprobe Domain Security

TLSv1.3 · DMARC

SECURITY

Resources

Access & Security 1

Authentication, authorization, and security posture

DomainSecurity
DomainSecurity

Operate 1

Status, limits, changes, and where to get help

Support
Support

Commercial 2

Pricing, plans, and the legal terms of use

PrivacyPolicy
PrivacyPolicy
 TermsOfService
TermsOfService

Company 2

The organization behind the API

Website
Website
 Blog
Blog

Source (apis.yml)

apis.yml Raw ↑ 
aid: nuprobe
name: NuProbe
description: 'NuProbe is a genomics and molecular diagnostics company founded in 2016 on technology licensed from the Wyss
  Institute at Harvard University and Rice University, with headquarters in Shanghai, China and a US subsidiary, NuProbe USA,
  in Houston, Texas. Its two core chemistries are Blocker Displacement Amplification (BDA), which enriches low-frequency DNA
  variants ahead of sequencing or PCR, and Quantitative Amplicon Sequencing (QASeq), a UMI-based multiplexed amplicon method
  for the simultaneous ultrasensitive detection of mutations and copy number variations from FFPE tissue, fresh or frozen
  tissue and cell-free DNA. The company sells research-use assay panels for oncology and reproductive health, custom assay
  development, and biopharma services, and has licensed or co-developed its chemistry with Bio-Rad, Oxford Nanopore, QIAGEN,
  Illumina and Bionano. NuProbe is an assay and reagent company: its bioinformatics and primer-design algorithms are delivered
  inside its products and services rather than as a public developer platform, and it publishes no API, SDK, developer portal
  or machine-readable specification of any kind.'
url: https://raw.githubusercontent.com/api-evangelist/nuprobe/refs/heads/main/apis.yml
deliveryModel:
  model: saas
  open_source: false
  commercial: true
  callable_host: false
  label: Hosted service · you call their endpoint
  confidence: medium
  source:
  - pricing
  generated: '2026-08-28'
  method: derived
accessModel:
  pricing: unknown
  onboarding: unknown
  trial: false
  try_now: false
  public: false
  label: Unknown
  confidence: low
  source:
  - security
  generated: '2026-09-02'
  method: derived
image: https://nuprobe.com/wp-content/uploads/2021/04/NuProbe-PMS-Logo_for-website.png
x-type: company
x-source: harvest:secondary-market
x-tier: profiled
x-tier-reason: enrichment-pass
specificationVersion: '0.20'
created: '2026-08-26'
modified: '2026-08-26'
tags:
- Company
- Life Sciences
- Genomics
- Molecular Diagnostics
- Next-Generation Sequencing
- Oncology
- Biotechnology
- Precision Medicine
- Laboratory
apis: []
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: Website
  url: https://nuprobe.com/
- type: Blog
  url: https://nuprobe.com/all-news/
- type: Support
  url: https://nuprobe.com/contact_us/
- type: PrivacyPolicy
  url: https://nuprobe.com/privacy-policy/
- type: TermsOfService
  url: https://nuprobe.com/nuprobe-usa-terms-and-conditions/
- type: DomainSecurity
  url: security/nuprobe-domain-security.yml
x-enrichment:
  date: '2026-08-26'
  status: minimal
  artifacts_added: 2
  pass: local-v1
x-coverage:
  state: none
  reason: not-a-software-company
  detail: NuProbe sells BDA and QASeq molecular-diagnostics assay kits, custom assay development and biopharma lab services
    rather than software; 1,199 archived URLs for nuprobe.com contain no /developers, /docs, /api, swagger, openapi or graphql
    path, both company GitHub organizations (NuProbeUSA, NuProbe-Bioinfo) hold zero public repositories, no nuprobe package
    exists on npm, PyPI, crates.io or RubyGems, and the marketing site itself is additionally returning a Cloudflare 526 origin
    error on every path during this pass.
  evidence:
  - url: https://nuprobe.com/openapi.json
    status: 526
  - url: https://nuprobe.com/.well-known/api-catalog
    status: 526
  - url: http://web.archive.org/cdx/search/cdx?url=nuprobe.com*&output=text&fl=original,statuscode&collapse=urlkey&limit=3000
    status: 200
  - url: https://api.github.com/orgs/NuProbeUSA/repos
    status: 200
  - url: https://registry.npmjs.org/-/v1/search?text=nuprobe
    status: 200
  checked: '2026-08-26'

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