Mana.bio

Mana.bio is an AI-driven drug-delivery biotechnology company specializing in programmable lipid nanoparticles (LNPs) for nucleic-acid therapeutics and vaccines, including mRNA, DNA, and CRISPR-based gene therapy. The company runs a closed-loop design-build-test-learn platform that uses machine-learning models to design novel LNP candidates, synthesizes dozens of formulations weekly via high-throughput automation, screens them with comprehensive assays, and feeds results back to continuously improve its models — targeting precise, optimized extrahepatic delivery. Mana.bio also operates Mina (ChatLNP), an AI agent that helps scientists explore curated literature, predict LNP properties, and optimize formulations, plus an LNP patents / freedom-to-operate map. The company is backed by a16z. Mana.bio publishes no first-party developer or product API; its only public agent surface is a Wix Site MCP endpoint and an llms.txt on its site.

Mana.bio is profiled on the APIs.io network. Tagged areas include Company, Biotechnology, Drug Delivery, Lipid Nanoparticles, and Gene Therapy.

Mana.bio’s developer surface includes engineering blog and 6 more developer resources.

🌐 Visit website 📡 Source on GitHub

6.2/100 minimal ▬ flat Agent 9/100 agent aware Full breakdown ↓
scored 2026-09-08 · rubric v0.20.0

0 APIs 1 MCP Servers

Company Biotechnology Drug Delivery Lipid Nanoparticles Gene Therapy Artificial Intelligence Machine-Learning Genetic Medicine mRNA

Kin Score

Kin Score How this is scored →
scored 2026-09-08 · rubric v0.20.0

Composite quality — 6.2/100 · minimal

Contract Quality 0.0 / 25

Developer Ergonomics 0.5 / 20

Access Clarity 0.0 / 20

Operational Transparency 0.0 / 13

Contract Governance 0.0 / 12

Discoverability 5.7 / 10

Agent readiness — 9/100 · agent aware

Machine-Readable Contract 0 / 18

Agentic Access Contract 0 / 10

Documented Reversibility 0 / 6

MCP Server 12 / 12

Machine-Readable Auth 0 / 10

Idempotency 0 / 9

Stable Error Semantics 0 / 8

Request/Response Examples 0 / 7

Rate-Limit Signaling 0 / 7

Typed Event Surface 0 / 6

Agent Skills 0 / 5

Well-Known Catalog 0 / 4

Consent & Bot Identity 0 / 3

A2A Agent Card 0 / 8

Dry-Run / Simulate Mode 0 / 4

Delegated User Identity 0 / 6

Protected Resource Metadata 0 / 5

Registration Without a Human 0 / 6

Agentic Commerce Well-Known Document 0 / 5

Create-or-Update Ergonomics could not be measured. We hold no machine-readable contract for this provider to read, so there is nothing to measure a write surface against. Excluded rather than scored zero: never-measured and measured-empty are different facts. Publishing an OpenAPI is what makes this facet — and several others — scorable at all.

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MCP Servers 1

Model Context Protocol servers that expose these APIs to AI agents.

Mana.bio Site MCP

MCP SERVER

Security Posture 1

Authentication, domain security, vulnerability disclosure, and trust-center signals.

Manabio Domain Security

TLSv1.3 · HSTS

SECURITY

Resources

Agent Surfaces 2

MCP servers, agent skills, and machine-readable catalogs

MCPServer

MCPServer

LLMsTxt

LLMsTxt

Access & Security 1

Authentication, authorization, and security posture

DomainSecurity

DomainSecurity

Company 3

The organization behind the API

Website

Website

Blog

Blog

Jobs

Jobs

Other 1

Properties that don't map to a standard resource type

Publications

Publications

Source (apis.yml)

aid: manabio
name: Mana.bio
description: Mana.bio is an AI-driven drug-delivery biotechnology company specializing in programmable lipid nanoparticles
  (LNPs) for nucleic-acid therapeutics and vaccines, including mRNA, DNA, and CRISPR-based gene therapy. The company runs
  a closed-loop design-build-test-learn platform that uses machine-learning models to design novel LNP candidates, synthesizes
  dozens of formulations weekly via high-throughput automation, screens them with comprehensive assays, and feeds results
  back to continuously improve its models — targeting precise, optimized extrahepatic delivery. Mana.bio also operates Mina
  (ChatLNP), an AI agent that helps scientists explore curated literature, predict LNP properties, and optimize formulations,
  plus an LNP patents / freedom-to-operate map. The company is backed by a16z. Mana.bio publishes no first-party developer
  or product API; its only public agent surface is a Wix Site MCP endpoint and an llms.txt on its site.
url: https://raw.githubusercontent.com/api-evangelist/manabio/refs/heads/main/apis.yml
x-type: company
x-source: vc-portfolio
x-backed-by:
- a16z
x-tier: stub
x-tier-reason: portfolio-lead
deliveryModel:
  model: unknown
  open_source: false
  commercial: false
  callable_host: false
  label: Delivery model not determined — needs a product licence on record
  confidence: low
  source:
  - none
  generated: '2026-08-28'
  method: derived
accessModel:
  pricing: unknown
  onboarding: unknown
  trial: false
  try_now: false
  public: false
  label: Unknown
  confidence: low
  source: []
  generated: '2026-07-22'
  method: derived
specificationVersion: '0.23'
created: '2026-07-17'
modified: '2026-07-20'
tags:
- Company
- Biotechnology
- Drug Delivery
- Lipid Nanoparticles
- Gene Therapy
- Artificial Intelligence
- Machine-Learning
- Genetic Medicine
- mRNA
tags_raw:
- Company
- Biotechnology
- Drug Delivery
- Lipid Nanoparticles
- Gene Therapy
- Artificial Intelligence
- Machine Learning
- Genetic Medicine
- mRNA
image: https://static.wixstatic.com/media/d7e63b_1d6eb702d51a4cdaad0396e94610de66~mv2.jpg/v1/fit/w_2500,h_1330,al_c/d7e63b_1d6eb702d51a4cdaad0396e94610de66~mv2.jpg
apis: []
x-enrichment:
  date: '2026-07-20'
  status: enriched
  artifacts_added: 3
  pass: local-v1
common:
- type: Website
  url: https://www.mana.bio/
- type: Blog
  url: https://www.mana.bio/news
- type: Publications
  url: https://www.mana.bio/publications
- type: Jobs
  url: https://www.mana.bio/jobs
- type: MCPServer
  name: Mana.bio Site MCP
  url: mcp/manabio-mcp.yml
- type: LLMsTxt
  url: llms/manabio-llms.txt
- type: DomainSecurity
  url: security/manabio-domain-security.yml
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io

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