Imbria Pharmaceuticals

Imbria Pharmaceuticals is a private, clinical-stage biopharmaceutical company based in the Boston area that is developing novel cardiovascular therapies targeting cardiac energy metabolism. Its lead candidate, ninerafaxstat, is a first-in-class partial fatty acid oxidation (pFOX) inhibitor designed to shift myocardial substrate utilization toward glucose oxidation, generating more ATP per unit of oxygen consumed and improving cardiac metabolic efficiency without affecting heart rate, rhythm, ejection fraction or blood pressure. Ninerafaxstat is in the global FORTITUDE-HCM Phase 2b trial (NCT07023614) for symptomatic non-obstructive hypertrophic cardiomyopathy (nHCM), which has no approved treatments, and holds FDA Orphan Drug Designation for that indication; a Phase 2b in cardiometabolic HFpEF is planned. The company is backed by RA Capital, SV Health Investors, Deep Track Capital, Catalio Capital Management, AN Ventures and Cytokinetics. Imbria is a therapeutics developer, not a software vendor, and publishes no public API, developer portal, SDK or machine-readable API contract.

Imbria Pharmaceuticals is profiled on the APIs.io network. Tagged areas include Company, Pharmaceuticals, Biotechnology, Life Sciences, and Cardiovascular.

Imbria Pharmaceuticals’ developer surface includes engineering blog, support, and 8 more developer resources.

🌐 Visit website 📡 Source on GitHub

11.2/100 emerging ▬ flat Agent 0/100 human only Full breakdown ↓
scored 2026-08-25 · rubric v0.14.0

0 APIs

Company Pharmaceuticals Biotechnology Life Sciences Cardiovascular Clinical Trials Drug Development Healthcare Therapeutics

Kin Score

Kin Score How this is scored →
scored 2026-08-25 · rubric v0.14.0

Composite quality — 11.2/100 · emerging

Contract Quality 0.0 / 21

Developer Ergonomics 1.2 / 17

Access Clarity 3.6 / 17

Operational Transparency 0.0 / 11

Contract Governance 0.0 / 10

Discoverability 4.9 / 9

Regulatory Posture 2.6 / 15

Agent readiness — 0/100 · human only

Machine-Readable Contract 0 / 18

Agentic Access Contract 0 / 10

Documented Reversibility 0 / 6

MCP Server 0 / 12

Machine-Readable Auth 0 / 10

Idempotency 0 / 9

Stable Error Semantics 0 / 8

Request/Response Examples 0 / 7

Rate-Limit Signaling 0 / 7

Typed Event Surface 0 / 6

Agent Skills 0 / 5

Well-Known Catalog 0 / 4

Consent & Bot Identity 0 / 3

A2A Agent Card 0 / 8

Dry-Run / Simulate Mode 0 / 4

Delegated User Identity 0 / 6

Protected Resource Metadata 0 / 5

Registration Without a Human 0 / 6

Agentic Commerce Surface 0 / 5

Regulatory Posture applies to this provider. Its tags matched the Health regime, so Regulatory Posture carries 15 points of the composite. If this regime is wrong for your business, say so on your provider repo — the applicability map is public and we will correct it.

The six quality facets above are damped to 85 points between them, because the conditional facet above carries the other 15. That is why each facet's contribution is shown against a damped maximum: raising a quality facet moves the composite by 85% of its nominal weight, not 100%. The full arithmetic is at apis.io/rating/.

Improve this rating by publishing the missing artifacts — every area above can be raised, and the full rubric is at apis.io/rating/. This rating is computed from github.com/api-evangelist/imbria-pharmaceuticals: open an issue to ask a question, or submit a pull request to add artifacts. Want it done for you? Prioritized profiling — $2,500 →

Agent Surfaces 1

MCP servers, agent skills, and machine-readable catalogs

LLMsTxt

LLMsTxt

Access & Security 1

Authentication, authorization, and security posture

DomainSecurity

DomainSecurity

Operate 1

Status, limits, changes, and where to get help

Support

Support

Commercial 2

Pricing, plans, and the legal terms of use

TermsOfService

TermsOfService

PrivacyPolicy

PrivacyPolicy

Company 5

The organization behind the API

Website

About

Blog

BlogRSS

LinkedIn

Source (apis.yml)

aid: imbria-pharmaceuticals
name: Imbria Pharmaceuticals
description: Imbria Pharmaceuticals is a private, clinical-stage biopharmaceutical company based in the Boston area that is
  developing novel cardiovascular therapies targeting cardiac energy metabolism. Its lead candidate, ninerafaxstat, is a first-in-class
  partial fatty acid oxidation (pFOX) inhibitor designed to shift myocardial substrate utilization toward glucose oxidation,
  generating more ATP per unit of oxygen consumed and improving cardiac metabolic efficiency without affecting heart rate,
  rhythm, ejection fraction or blood pressure. Ninerafaxstat is in the global FORTITUDE-HCM Phase 2b trial (NCT07023614) for
  symptomatic non-obstructive hypertrophic cardiomyopathy (nHCM), which has no approved treatments, and holds FDA Orphan Drug
  Designation for that indication; a Phase 2b in cardiometabolic HFpEF is planned. The company is backed by RA Capital, SV
  Health Investors, Deep Track Capital, Catalio Capital Management, AN Ventures and Cytokinetics. Imbria is a therapeutics
  developer, not a software vendor, and publishes no public API, developer portal, SDK or machine-readable API contract.
image: https://imbria.com/wp-content/uploads/2025/09/imbria_logo-1.svg
url: https://raw.githubusercontent.com/api-evangelist/imbria-pharmaceuticals/refs/heads/main/apis.yml
x-type: company
x-source: harvest:secondary-market
specificationVersion: '0.20'
created: '2026-08-22'
modified: '2026-08-22'
tags:
- Company
- Pharmaceuticals
- Biotechnology
- Life Sciences
- Cardiovascular
- Clinical Trials
- Drug Development
- Healthcare
- Therapeutics
apis: []
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: DomainSecurity
  url: security/imbria-pharmaceuticals-domain-security.yml
- type: Website
  url: https://imbria.com/
- type: About
  url: https://imbria.com/our-story/
- type: Blog
  url: https://imbria.com/investors-media/press-releases/
- type: BlogRSS
  url: https://imbria.com/feed/
- type: Support
  url: https://imbria.com/contact/
- type: TermsOfService
  url: https://imbria.com/terms-of-use/
- type: PrivacyPolicy
  url: https://imbria.com/privacy-policy/
- type: LinkedIn
  url: https://www.linkedin.com/company/imbria/
- type: LLMsTxt
  url: llms/imbria-pharmaceuticals-llms.txt
x-enrichment:
  date: '2026-08-22'
  status: minimal
  artifacts_added: 3
  pass: local-v1
x-coverage:
  state: none
  reason: not-a-software-company
  detail: Imbria Pharmaceuticals is a private clinical-stage biopharma developing ninerafaxstat for cardiovascular disease;
    imbria.com is a WordPress marketing site whose only machine-readable surface is the default WordPress core REST API at
    /wp-json/, and every developer-program path probed (/developers, /docs, /api, /openapi.json, /graphql, /llms.txt, /apis.json
    and eight /.well-known/ documents) returned the site's standard 404.
  evidence:
  - url: https://imbria.com/developers
    status: 404
  - url: https://imbria.com/openapi.json
    status: 404
  - url: https://imbria.com/.well-known/api-catalog
    status: 404
  - url: https://imbria.com/.well-known/agent-card.json
    status: 404
  - url: https://imbria.com/wp-json
    status: 200
  - url: https://github.com/imbria
    status: 404
  checked: '2026-08-22'

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