Cirius Therapeutics

Cirius Therapeutics, Inc. is a privately held clinical-stage pharmaceutical company based in Grand Rapids, Michigan, developing oral therapies for chronic metabolic diseases driven by insulin resistance, including Type 2 Diabetes, Type 1 Diabetes, obesity and gestational diabetes. Its lead candidate, azemiglitazone (CIR-0602K / MSDC-0602K), is a next-generation insulin sensitizer that inhibits the mitochondrial pyruvate carrier (MPC) to re-balance mitochondrial metabolism, improve glycemic control, preserve lean muscle mass and shift visceral fat to subcutaneous and brown adipose tissue, including in combination with GLP-1 receptor agonists such as tirzepatide. The company publishes a corporate marketing website only; it operates no developer program, public API, or machine-readable API contract.

Cirius Therapeutics is profiled on the APIs.io network. Tagged areas include Company, Pharmaceuticals, Biotechnology, Life Sciences, and Healthcare.

Cirius Therapeutics’ developer surface includes product news and 7 more developer resources.

🌐 Visit website 📡 Source on GitHub

6.0/100 minimal ▬ flat Agent 0/100 human only Full breakdown ↓
scored 2026-08-17 · rubric v0.11.0

0 APIs

CompanyPharmaceuticalsBiotechnologyLife SciencesHealthcareClinical TrialsMetabolic DiseaseDiabetes

Kin Score

Kin Score How this is scored →
scored 2026-08-17 · rubric v0.11.0

Composite quality — 6.0/100 · minimal

Contract Quality 0.0 / 21

Developer Ergonomics 0.0 / 17

Commercial Clarity 0.0 / 17

Operational Transparency 0.0 / 11

Governance 0.0 / 10

Discoverability 4.9 / 9

Regulatory Posture 1.1 / 15

Agent readiness — 0/100 · human only

Machine-Readable Contract 0 / 18

Agentic Access Contract 0 / 10

MCP Server 0 / 12

Machine-Readable Auth 0 / 10

Idempotency 0 / 9

Stable Error Semantics 0 / 8

Request/Response Examples 0 / 7

Rate-Limit Signaling 0 / 7

Typed Event Surface 0 / 6

Agent Skills 0 / 5

Well-Known Catalog 0 / 4

Consent & Bot Identity 0 / 3

A2A Agent Card 0 / 8

Dry-Run / Simulate Mode 0 / 4

Regulatory Posture applies to this provider. Its tags matched the Health regime, so Regulatory Posture carries 15 points of the composite. If this regime is wrong for your business, say so on your provider repo — the applicability map is public and we will correct it.

The six quality facets above are damped to 85 points between them, because the conditional facet above carries the other 15. That is why each facet's contribution is shown against a damped maximum: raising a quality facet moves the composite by 85% of its nominal weight, not 100%. The full arithmetic is at apis.io/rating/.

Improve this rating by publishing the missing artifacts — every area above can be raised, and the full rubric is at apis.io/rating/. This rating is computed from github.com/api-evangelist/cirius-therapeutics: open an issue to ask a question, or submit a pull request to add artifacts. Want it done for you? Prioritized profiling — $2,500 →

Agent Surfaces 1

MCP servers, agent skills, and machine-readable catalogs

LLMsTxt

LLMsTxt

Access & Security 1

Authentication, authorization, and security posture

DomainSecurity

DomainSecurity

Operate 1

Status, limits, changes, and where to get help

Contact

Contact

Company 2

The organization behind the API

Website

Website

News

News

Other 3

Properties that don't map to a standard resource type

Team

Team

Science

Science

SecondaryMarket

SecondaryMarket

Source (apis.yml)

aid: cirius-therapeutics
name: Cirius Therapeutics
description: Cirius Therapeutics, Inc. is a privately held clinical-stage pharmaceutical company based in Grand Rapids, Michigan,
  developing oral therapies for chronic metabolic diseases driven by insulin resistance, including Type 2 Diabetes, Type 1
  Diabetes, obesity and gestational diabetes. Its lead candidate, azemiglitazone (CIR-0602K / MSDC-0602K), is a next-generation
  insulin sensitizer that inhibits the mitochondrial pyruvate carrier (MPC) to re-balance mitochondrial metabolism, improve
  glycemic control, preserve lean muscle mass and shift visceral fat to subcutaneous and brown adipose tissue, including in
  combination with GLP-1 receptor agonists such as tirzepatide. The company publishes a corporate marketing website only;
  it operates no developer program, public API, or machine-readable API contract.
url: https://raw.githubusercontent.com/api-evangelist/cirius-therapeutics/refs/heads/main/apis.yml
image: https://img1.wsimg.com/isteam/ip/40701c08-78b4-429c-9131-4a2e35286e89/Cirius_1420x1200_Full-baa8525.jpg
x-type: company
x-source: harvest:secondary-market
x-tier: stub
x-tier-reason: harvest
specificationVersion: '0.20'
created: '2026-08-09'
modified: '2026-08-09'
tags:
- Company
- Pharmaceuticals
- Biotechnology
- Life Sciences
- Healthcare
- Clinical Trials
- Metabolic Disease
- Diabetes
apis: []
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: DomainSecurity
  url: security/cirius-therapeutics-domain-security.yml
- type: LLMsTxt
  url: llms/cirius-therapeutics-llms.txt
- type: Website
  url: https://ciriustx.com/
- type: News
  url: https://ciriustx.com/news
- type: Contact
  url: https://ciriustx.com/contact
- type: Team
  url: https://ciriustx.com/team
- type: Science
  url: https://ciriustx.com/science
- type: SecondaryMarket
  url: https://forgeglobal.com/cirius-therapeutics_stock/
x-enrichment:
  date: '2026-08-09'
  status: minimal
  artifacts_added: 2
  pass: local-v1
x-coverage:
  state: none
  reason: not-a-software-company
  detail: Cirius Therapeutics is a clinical-stage pharmaceutical company whose entire web presence is a five-page GoDaddy-built
    marketing site (Home/Team/Science/News/Contact) about the MPC inhibitor azemiglitazone — there is no developer section,
    no API host, no GitHub organization, and every contract-discovery path on ciriustx.com returned a hard 404.
  evidence:
  - url: https://ciriustx.com/
    status: 200
  - url: https://ciriustx.com/llms.txt
    status: 200
  - url: https://ciriustx.com/openapi.json
    status: 404
  - url: https://ciriustx.com/.well-known/agent-card.json
    status: 404
  - url: https://ciriustx.com/.well-known/security.txt
    status: 404
  - url: https://api.github.com/orgs/cirius-therapeutics
    status: 404
  checked: '2026-08-09'