Circular Genomics

Circular Genomics is a San Diego, California precision-neurology diagnostics company that uses brain-derived circular RNA (circRNA) as a class of stable, blood-based biomarkers for psychiatric and neurological disease. Spun out of the University of New Mexico in 2021 and now resident at Lilly Gateway Labs in San Diego, the company builds CircPath, a proprietary molecular-intelligence platform that discovers, validates and translates circRNA signals into biological insight, and productizes it as research and clinical assays: Discover 1600+ (whole-transcriptome circRNA sequencing across 1,600+ brain-derived circRNAs with pathway-level analysis), AD Predict and AD Detect for Alzheimer's disease, and MindLight, an SSRI antidepressant response test for major depressive disorder. Test ordering and results delivery for licensed healthcare providers run through a login-gated provider portal at mindlight.circulargenomics.com, which is a white-labeled CrelioHealth laboratory information system rather than a first-party developer surface. Circular Genomics publishes no public API, SDK, webhook or developer documentation of any kind.

Circular Genomics is profiled on the APIs.io network. Tagged areas include Company, Biotechnology, Diagnostics, Genomics, and Precision Medicine.

Circular Genomics’ developer surface includes engineering blog and 17 more developer resources.

11.5/100 minimal ▬ flat Agent 0/100 human only Full breakdown ↓
scored 2026-08-17 · rubric v0.11.0
0 APIs
CompanyBiotechnologyDiagnosticsGenomicsPrecision MedicineNeurologyLife SciencesHealthClinical LaboratoryBiomarkers

Kin Score

Kin Score Kin Score How this is scored →
scored 2026-08-17 · rubric v0.11.0
Composite quality — 11.5/100 · minimal
Contract Quality 0.0 / 21
Developer Ergonomics 0.4 / 17
Commercial Clarity 3.6 / 17
Operational Transparency 0.0 / 11
Governance 0.0 / 10
Discoverability 4.9 / 9
Regulatory Posture 2.6 / 15
Agent readiness — 0/100 · human only
Machine-Readable Contract 0 / 18
Agentic Access Contract 0 / 10
MCP Server 0 / 12
Machine-Readable Auth 0 / 10
Idempotency 0 / 9
Stable Error Semantics 0 / 8
Request/Response Examples 0 / 7
Rate-Limit Signaling 0 / 7
Typed Event Surface 0 / 6
Agent Skills 0 / 5
Well-Known Catalog 0 / 4
Consent & Bot Identity 0 / 3
A2A Agent Card 0 / 8
Dry-Run / Simulate Mode 0 / 4
Regulatory Posture applies to this provider. Its tags matched the Health regime, so Regulatory Posture carries 15 points of the composite. If this regime is wrong for your business, say so on your provider repo — the applicability map is public and we will correct it.
The six quality facets above are damped to 85 points between them, because the conditional facet above carries the other 15. That is why each facet's contribution is shown against a damped maximum: raising a quality facet moves the composite by 85% of its nominal weight, not 100%. The full arithmetic is at apis.io/rating/.
Improve this rating by publishing the missing artifacts — every area above can be raised, and the full rubric is at apis.io/rating/. This rating is computed from github.com/api-evangelist/circular-genomics: open an issue to ask a question, or submit a pull request to add artifacts. Want it done for you? Prioritized profiling — $2,500 →

Security Posture 1

Authentication, domain security, vulnerability disclosure, and trust-center signals.

Circular Genomics Domain Security

TLSv1.3 · HSTS · DNSSEC · DMARC

SECURITY

Resources

Get Started 1

Portal, sign-up, and the first successful call

Agent Surfaces 1

MCP servers, agent skills, and machine-readable catalogs

Access & Security 1

Authentication, authorization, and security posture

Operate 1

Status, limits, changes, and where to get help

Commercial 2

Pricing, plans, and the legal terms of use

Company 8

The organization behind the API

Scroll for all 8

Other 4

Properties that don't map to a standard resource type

Source (apis.yml)

apis.yml Raw ↑
aid: circular-genomics
name: Circular Genomics
description: 'Circular Genomics is a San Diego, California precision-neurology diagnostics company that uses brain-derived
  circular RNA (circRNA) as a class of stable, blood-based biomarkers for psychiatric and neurological disease. Spun out of
  the University of New Mexico in 2021 and now resident at Lilly Gateway Labs in San Diego, the company builds CircPath, a
  proprietary molecular-intelligence platform that discovers, validates and translates circRNA signals into biological insight,
  and productizes it as research and clinical assays: Discover 1600+ (whole-transcriptome circRNA sequencing across 1,600+
  brain-derived circRNAs with pathway-level analysis), AD Predict and AD Detect for Alzheimer''s disease, and MindLight, an
  SSRI antidepressant response test for major depressive disorder. Test ordering and results delivery for licensed healthcare
  providers run through a login-gated provider portal at mindlight.circulargenomics.com, which is a white-labeled CrelioHealth
  laboratory information system rather than a first-party developer surface. Circular Genomics publishes no public API, SDK,
  webhook or developer documentation of any kind.'
url: https://raw.githubusercontent.com/api-evangelist/circular-genomics/refs/heads/main/apis.yml
image: https://cdn.prod.website-files.com/69f294bcc4f8261224416905/6a5e4d5072472bd95c583d2f_Circular%20Genomics%20Monogram%401x.png
x-type: company
x-source: harvest:secondary-market
x-tier: stub
x-tier-reason: harvest
specificationVersion: '0.20'
created: '2026-08-09'
modified: '2026-08-09'
tags:
- Company
- Biotechnology
- Diagnostics
- Genomics
- Precision Medicine
- Neurology
- Life Sciences
- Health
- Clinical Laboratory
- Biomarkers
apis: []
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: DomainSecurity
  url: security/circular-genomics-domain-security.yml
- type: LLMsTxt
  url: llms/circular-genomics-llms.txt
- type: Website
  url: https://www.circulargenomics.com/
- type: About
  url: https://www.circulargenomics.com/about
- type: Products
  url: https://www.circulargenomics.com/products
- type: Blog
  url: https://www.circulargenomics.com/news
- type: Contact
  url: https://www.circulargenomics.com/contact
- type: Partners
  url: https://www.circulargenomics.com/partnerships
- type: Publications
  url: https://www.circulargenomics.com/publications-resources
- type: Careers
  url: https://www.circulargenomics.com/careers
- type: TermsOfService
  url: https://www.circulargenomics.com/terms-of-use
- type: PrivacyPolicy
  url: https://www.circulargenomics.com/privacy
- type: CookiePolicy
  url: https://www.circulargenomics.com/cookie-policy
- type: ProviderPortal
  url: https://mindlight.circulargenomics.com/
- type: LinkedIn
  url: https://www.linkedin.com/company/circulargenomics
- type: Twitter
  url: https://x.com/CircGenomics
- type: Crunchbase
  url: https://www.crunchbase.com/organization/circular-genomics
- type: SecondaryMarket
  url: https://forgeglobal.com/circular-genomics_stock/
x-enrichment:
  date: '2026-08-09'
  status: minimal
  artifacts_added: 3
  pass: local-v1
x-coverage:
  state: none
  reason: no-developer-program
  detail: 'Circular Genomics ships clinical circRNA assays, not software — its only logged-in surface, the MindLight provider
    portal at mindlight.circulargenomics.com, is a white-labeled CrelioHealth LIS (the response carries `server: Crelio`)
    for test ordering by licensed clinicians, and every spec, /.well-known/ and developer path probed on both company hosts
    returned 404.'
  evidence:
  - url: https://www.circulargenomics.com/openapi.json
    status: 404
  - url: https://www.circulargenomics.com/developers
    status: 404
  - url: https://mindlight.circulargenomics.com/openapi.json
    status: 404
  - url: https://mindlight.circulargenomics.com/.well-known/agent-card.json
    status: 404
  - url: https://www.circulargenomics.com/sitemap.xml
    status: 200
  - url: https://api.github.com/users/circular-genomics/repos
    status: 200
  checked: '2026-08-09'