Be Biopharma

Be Biopharma (Be Bio) is a Cambridge, Massachusetts clinical-stage biotechnology company founded in October 2020 by Longwood Fund together with B cell engineering researchers David Rawlings, M.D. and Richard James, Ph.D. of Seattle Children's Research Institute. The company develops engineered B Cell Medicines (BCMs) — a patient's own B cells engineered to produce a therapeutic protein — for genetic disease, cancer and other serious conditions. Its lead candidate, BE-101, inserted a functional Factor IX gene into primary human B cells for hemophilia B and held FDA Orphan Drug and Fast Track designations; a second program, BE-102, targeted hypophosphatasia. The company raised $82M in October 2024 and $92M in a January 2025 Series C, dosed the first participant in the Phase 1/2 BeCoMe-9 trial in July 2025, and terminated that trial in June 2026 for stated strategic business reasons. Be Biopharma is a therapeutics developer, not a software company: it has never published a developer program, API, SDK or machine-readable contract.

Be Biopharma is profiled on the APIs.io network. Tagged areas include Company, Biotechnology, Life Sciences, Cell Therapy, and Gene Therapy.

🌐 Visit website 📡 Source on GitHub

3.7/100 minimal ▬ flat Agent 0/100 human only Full breakdown ↓
scored 2026-09-08 · rubric v0.20.0

0 APIs

Company Biotechnology Life Sciences Cell Therapy Gene Therapy Pharmaceuticals Healthcare Clinical Trials Rare Disease

Kin Score

Kin Score How this is scored →
scored 2026-09-08 · rubric v0.20.0

Composite quality — 3.7/100 · minimal

Contract Quality 0.0 / 21

Developer Ergonomics 0.0 / 17

Access Clarity 0.0 / 17

Operational Transparency 0.0 / 11

Contract Governance 0.0 / 10

Discoverability 4.6 / 9

Regulatory Posture 1.1 / 15

Agent readiness — 0/100 · human only

Machine-Readable Contract 0 / 18

Agentic Access Contract 0 / 10

Documented Reversibility 0 / 6

MCP Server 0 / 12

Machine-Readable Auth 0 / 10

Idempotency 0 / 9

Stable Error Semantics 0 / 8

Request/Response Examples 0 / 7

Rate-Limit Signaling 0 / 7

Typed Event Surface 0 / 6

Agent Skills 0 / 5

Well-Known Catalog 0 / 4

Consent & Bot Identity 0 / 3

A2A Agent Card 0 / 8

Dry-Run / Simulate Mode 0 / 4

Delegated User Identity 0 / 6

Protected Resource Metadata 0 / 5

Registration Without a Human 0 / 6

Agentic Commerce Well-Known Document 0 / 5

Regulatory Posture applies to this provider. Its tags matched the Health regime, so Regulatory Posture carries 15 points of the composite. If this regime is wrong for your business, say so on your provider repo — the applicability map is public and we will correct it.

Create-or-Update Ergonomics could not be measured. We hold no machine-readable contract for this provider to read, so there is nothing to measure a write surface against. Excluded rather than scored zero: never-measured and measured-empty are different facts. Publishing an OpenAPI is what makes this facet — and several others — scorable at all.

The six quality facets above are damped to 85 points between them, because the conditional facet above carries the other 15. That is why each facet's contribution is shown against a damped maximum: raising a quality facet moves the composite by 85% of its nominal weight, not 100%. The full arithmetic is at apis.io/rating/.

Improve this rating by publishing the missing artifacts — every area above can be raised, and the full rubric is at apis.io/rating/. Every facet and dimension name above is a link: it opens that measurement's own page — what it means, the exact checks that feed it, how the whole catalog distributes on it, and the providers at the top of it. This rating is computed from github.com/api-evangelist/be-biopharma: open an issue to ask a question, or submit a pull request to add artifacts. Submit an artifact on GitHub — free → Manage your own listing — the Influence plan, $499/mo →

Security Posture 1

Authentication, domain security, vulnerability disclosure, and trust-center signals.

Be Biopharma Domain Security

no transport/DNS hardening detected

SECURITY

Resources

Agent Surfaces 1

MCP servers, agent skills, and machine-readable catalogs

LLMsTxt

LLMsTxt

Access & Security 1

Authentication, authorization, and security posture

DomainSecurity

DomainSecurity

Company 2

The organization behind the API

Website

Website

LinkedIn

Other 2

Properties that don't map to a standard resource type

Archive

Source (apis.yml)

aid: be-biopharma
name: Be Biopharma
description: 'Be Biopharma (Be Bio) is a Cambridge, Massachusetts clinical-stage biotechnology company founded in October
  2020 by Longwood Fund together with B cell engineering researchers David Rawlings, M.D. and Richard James, Ph.D. of Seattle
  Children''s Research Institute. The company develops engineered B Cell Medicines (BCMs) — a patient''s own B cells engineered
  to produce a therapeutic protein — for genetic disease, cancer and other serious conditions. Its lead candidate, BE-101,
  inserted a functional Factor IX gene into primary human B cells for hemophilia B and held FDA Orphan Drug and Fast Track
  designations; a second program, BE-102, targeted hypophosphatasia. The company raised $82M in October 2024 and $92M in a
  January 2025 Series C, dosed the first participant in the Phase 1/2 BeCoMe-9 trial in July 2025, and terminated that trial
  in June 2026 for stated strategic business reasons. Be Biopharma is a therapeutics developer, not a software company: it
  has never published a developer program, API, SDK or machine-readable contract.'
url: https://raw.githubusercontent.com/api-evangelist/be-biopharma/refs/heads/main/apis.yml
x-type: company
x-source: harvest:secondary-market
x-tier: stub
x-tier-reason: harvest
deliveryModel:
  model: unknown
  open_source: false
  commercial: false
  callable_host: false
  label: Delivery model not determined — needs a product licence on record
  confidence: low
  source:
  - none
  generated: '2026-08-28'
  method: derived
accessModel:
  pricing: unknown
  onboarding: unknown
  trial: false
  try_now: false
  public: false
  label: Unknown
  confidence: low
  source:
  - security
  generated: '2026-09-02'
  method: derived
specificationVersion: '0.23'
created: '2026-08-06'
modified: '2026-08-06'
tags:
- Company
- Biotechnology
- Life Sciences
- Cell Therapy
- Gene Therapy
- Pharmaceuticals
- Healthcare
- Clinical Trials
- Rare Disease
apis: []
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: DomainSecurity
  url: security/be-biopharma-domain-security.yml
- type: LLMsTxt
  url: llms/be-biopharma-llms.txt
- type: Website
  url: https://be.bio/
- type: Archive
  url: https://web.archive.org/web/20260513184102/https://be.bio/
- type: LinkedIn
  url: https://www.linkedin.com/company/be-biopharma-inc
- type: SecondaryMarket
  url: https://forgeglobal.com/be-biopharma_stock/
x-enrichment:
  date: '2026-08-06'
  status: minimal
  artifacts_added: 2
  pass: local-v1
x-coverage:
  state: none
  reason: defunct
  detail: Be Biopharma's own domain be.bio no longer resolves — its authoritative nameservers (ns1.g02.cfdns.net) return SOA
    only for both the apex and www, so there is no host left to probe; the site was last archived 2026-05-13, the company
    terminated its lead BeCoMe-9 hemophilia B trial in June 2026, and LinkedIn now lists a single employee.
  evidence:
  - url: https://be.bio/
    status: 0
  - url: https://www.be.bio/.well-known/security.txt
    status: 404
  - url: https://www.be.bio/.well-known/openid-configuration
    status: 404
  - url: https://www.be.bio/.well-known/ai-plugin.json
    status: 404
  - url: https://web.archive.org/web/20260513184102/https://be.bio/
    status: 200
  - url: https://api.github.com/search/users?q=bebiopharma+OR+be-biopharma
    status: 200
  checked: '2026-08-06'

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