Astraea website screenshot

Astraea

Astraea is a Y Combinator-backed (Spring 2026) clinical trial automation platform that gives pharmaceutical sponsors, biotechs, and CROs an AI operating system for clinical development. Founded by Joshua Wang and Sanmay Sarada, the platform orchestrates specialized AI agents across the full biometrics lifecycle - standards mapping, data normalization, CDISC mapping, SDTM and ADaM dataset generation, TFLs/TLFs, SAP, eCRFs, Define-XML, QC, and submission documents - turning a protocol and raw study data into FDA-submission-ready output. Astraea is positioned as sponsor-run software rather than a CRO: it runs inside the customer's own secure environment so clinical data never reaches Astraea's servers, with 21 CFR Part 11 compliance and audit-ready, standards-native traceability. The company reports serving 10+ global pharma and biotech sponsors with 30-50% faster reporting cycles.

Astraea is profiled on the APIs.io network. Tagged areas include Company, Clinical Trials, Healthcare, Life Sciences, and Artificial Intelligence.

Astraea’s developer surface includes support and 3 more developer resources.

🌐 Visit website📡 Profile data on GitHub
5.3/100 minimal ▬ flat Agent 0/100 human only Front door AI 5/6 prominent Full breakdown ↓
scored 2026-10-17 · rubric v0.24.0
0 APIs
CompanyClinical TrialsHealthcareLife SciencesArtificial IntelligenceBiometricsClinical DevelopmentPharmaceuticalsCDISCRegulatory

Kin Score

Kin Score Kin Score How this is scored →
scored 2026-10-17 · rubric v0.24.0
Composite quality — 5.3/100 · minimal
Contract Quality 0.0 / 21
Developer Ergonomics 0.8 / 17
Access Clarity 0.0 / 17
Operational Transparency 0.0 / 11
Contract Governance 0.0 / 10
Discoverability 4.7 / 9
Regulatory Posture 0.6 / 15
Agent readiness — 0/100 · human only
Machine-Readable Contract 0 / 18
Agentic Access Contract 0 / 10
Documented Reversibility 0 / 6
MCP Server 0 / 12
Machine-Readable Auth 0 / 10
Idempotency 0 / 9
Stable Error Semantics 0 / 8
Request/Response Examples 0 / 7
Rate-Limit Signaling 0 / 7
Typed Event Surface 0 / 6
Agent Skills 0 / 5
Well-Known Catalog 0 / 4
Consent & Bot Identity 0 / 3
A2A Agent Card 0 / 8
Dry-Run / Simulate Mode 0 / 4
Delegated User Identity 0 / 6
Protected Resource Metadata 0 / 5
Registration Without a Human 0 / 6
Agentic Commerce Well-Known Document 0 / 5
Regulatory Posture applies to this provider. Its tags matched the Health regime, so Regulatory Posture carries 15 points of the composite. If this regime is wrong for your business, say so on your provider repo — the applicability map is public and we will correct it.
Create-or-Update Ergonomics could not be measured. We hold no machine-readable contract for this provider to read, so there is nothing to measure a write surface against. Excluded rather than scored zero: never-measured and measured-empty are different facts. Publishing an OpenAPI is what makes this facet — and several others — scorable at all.
The six quality facets above are damped to 85 points between them, because the conditional facet above carries the other 15. That is why each facet's contribution is shown against a damped maximum: raising a quality facet moves the composite by 85% of its nominal weight, not 100%. The full arithmetic is at apis.io/rating/.
Improve this rating by publishing the missing artifacts — every area above can be raised, and the full rubric is at apis.io/rating/. Every facet and dimension name above is a link: it opens that measurement's own page — what it means, the exact checks that feed it, how the whole catalog distributes on it, and the providers at the top of it. This rating is computed from github.com/api-evangelist/astraea: open an issue to ask a question, or submit a pull request to add artifacts. Submit an artifact on GitHub — free → Manage your own listing — the Influence plan, $499/mo →

Standards implemented 1

Standards this provider implements or carries. De facto ones are profiled and measured by the API Commons; formal ones come from the standards directory and are linked by the provider's own tags. The evidence column says how each claim was established — not that it was made.

CDISC
tagged — the provider's own APIs.json carries the standard as a tag; implementation not verified

Security Posture 1

Authentication, domain security, vulnerability disclosure, and trust-center signals.

Astraea Domain Security

TLSv1.3 · DMARC

SECURITY

Resources

Agent Surfaces 1

MCP servers, agent skills, and machine-readable catalogs

LLMsTxt
LLMsTxt

Access & Security 1

Authentication, authorization, and security posture

DomainSecurity
DomainSecurity

Operate 1

Status, limits, changes, and where to get help

Support
Support

Company 1

The organization behind the API

Website
Website

Source (apis.yml)

apis.yml Raw ↑ 
aid: astraea
deliveryModel:
  model: unknown
  open_source: false
  commercial: false
  callable_host: false
  label: Delivery model not determined — needs a product licence on record
  confidence: low
  source:
  - none
  generated: '2026-08-28'
  method: derived
accessModel:
  pricing: unknown
  onboarding: unknown
  trial: false
  try_now: false
  public: false
  label: Unknown
  confidence: low
  source: []
  generated: '2026-07-22'
  method: derived
image: https://kinlane-images.s3.amazonaws.com/shared/apis-json/icons/astraea.png
name: Astraea
description: 'Astraea is a Y Combinator-backed (Spring 2026) clinical trial automation platform that gives pharmaceutical
  sponsors, biotechs, and CROs an AI operating system for clinical development. Founded by Joshua Wang and Sanmay Sarada,
  the platform orchestrates specialized AI agents across the full biometrics lifecycle - standards mapping, data normalization,
  CDISC mapping, SDTM and ADaM dataset generation, TFLs/TLFs, SAP, eCRFs, Define-XML, QC, and submission documents - turning
  a protocol and raw study data into FDA-submission-ready output. Astraea is positioned as sponsor-run software rather than
  a CRO: it runs inside the customer''s own secure environment so clinical data never reaches Astraea''s servers, with 21
  CFR Part 11 compliance and audit-ready, standards-native traceability. The company reports serving 10+ global pharma and
  biotech sponsors with 30-50% faster reporting cycles.'
url: https://raw.githubusercontent.com/api-evangelist/astraea/refs/heads/main/apis.yml
x-type: company
x-source: vc-portfolio
x-backed-by:
- y-combinator
x-tier: stub
x-tier-reason: portfolio-lead
specificationVersion: '0.23'
created: '2026-07-17'
modified: '2026-07-18'
tags:
- Company
- Clinical Trials
- Healthcare
- Life Sciences
- Artificial Intelligence
- Biometrics
- Clinical Development
- Pharmaceuticals
- CDISC
- Regulatory
tags_raw:
- Company
- Clinical Trials
- Healthcare
- Life Sciences
- Artificial Intelligence
- Biometrics
- Clinical Development
- Pharmaceutical
- CDISC
- Regulatory
apis: []
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: Website
  url: https://www.tryastraea.com/
- type: Support
  url: https://www.tryastraea.com/contact
- type: DomainSecurity
  url: security/astraea-domain-security.yml
- type: LLMsTxt
  url: llms/astraea-llms.txt
x-enrichment:
  date: '2026-07-19'
  status: backfilled
  pass: local-v1
  note: backfilled from .gitignore signal + verified work evidence

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