A2 Biotherapeutics

A2 Biotherapeutics (A2 Bio) is a clinical-stage biotechnology company headquartered in Agoura Hills, California, founded in 2018 by Alexander Kamb, Michael Gallo and Paul Kang. It develops logic-gated cell therapies for solid tumors on its proprietary Tmod platform, a two-receptor activator/blocker design that lets an engineered T cell attack tumor cells which have lost an HLA allele while sparing normal cells that retain it. A2 Bio operates no developer API programme and publishes no product, clinical or research API. It is catalogued here because its corporate website runs a live WordPress REST API with 298 discoverable routes, and because that same install exposes two Model Context Protocol servers guarded by an OAuth 2.1 authorization server the host advertises through RFC 8414 and RFC 9728 metadata.

A2 Biotherapeutics is listed with 2 APIs on the APIs.io network, including MCP API, and 1 more. Tagged areas include Company, Biotechnology, Life Sciences, Cell Therapy, and Immuno-Oncology.

The A2 Biotherapeutics catalog on APIs.io includes 1 Spectral governance ruleset.

A2 Biotherapeutics’ developer surface includes engineering blog, authentication, and 28 more developer resources.

🌐 Visit website 📡 Profile data on GitHub

27.1/100 thin ▬ flat Agent 44/100 agent ready Front door AI 1/6 silent Heartbeat 100/100 alive saas Full breakdown ↓
scored 2026-11-13 · rubric v0.28.0 · Show this score on your site →

2 APIs 1 MCP Servers 2 Agent Skills

Company Biotechnology Life Sciences Cell Therapy Immuno-Oncology Oncology Pharmaceuticals Clinical Trials Healthcare MCP WordPress

Kin Score

Kin Score How this is scored →
scored 2026-11-13 · rubric v0.28.0

Composite quality — 27.1/100 · thin

Contract Quality 3.1 / 19

Developer Ergonomics 3.8 / 15

Access Clarity 5.4 / 15

Operational Transparency 0.0 / 10

Contract Governance 1.6 / 9

Discoverability 4.6 / 8

Regulatory Posture 4.8 / 15

Create-or-Update Ergonomics 0.0 / 10

Agent readiness — 44/100 · agent ready

Machine-Readable Contract 18 / 18

Agentic Access Contract 0 / 10

Documented Reversibility 0 / 6

MCP Server 12 / 12

Machine-Readable Auth 10 / 10

Idempotency 0 / 9

Stable Error Semantics 8 / 8

Request/Response Examples 0 / 7

Rate-Limit Signaling 0 / 7

Typed Event Surface 0 / 6

Agent Skills 5 / 5

Well-Known Catalog 0 / 4

Consent & Bot Identity 3 / 3

A2A Agent Card 0 / 8

Dry-Run / Simulate Mode 0 / 4

Delegated User Identity 6 / 6

Protected Resource Metadata 5 / 5

Registration Without a Human 6 / 6

Agentic Commerce Well-Known Document 0 / 5

Pagination 5 / 5

Distinct Operations 3 / 3

MCP Tool Quality 6 / 6

Regulatory Posture applies to this provider. Its tags matched the Health regime, so Regulatory Posture carries 15 points of the composite. If this regime is wrong for your business, say so on your provider repo — the applicability map is public and we will correct it.

Create-or-Update Ergonomics applies to this provider. This API accepts writes, so it carries 10 points of the composite. It is scored from the published contracts themselves: whether a caller can create-or-update in one call, whether the write accepts a key the caller already holds, and whether the response says which branch ran. Without that, every write needs a search-and-branch in front of it, and the first time that check is skipped a duplicate record is created. Scored against the observed mean rather than raw — a provider at the catalog average is unchanged by this facet, not penalised by it.

The six quality facets above are damped to 75 points between them, because the conditional facet above carries the other 25. That is why each facet's contribution is shown against a damped maximum: raising a quality facet moves the composite by 75% of its nominal weight, not 100%. The full arithmetic is at apis.io/rating/.

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Agent readiness — checks not met, largest first (exact, from this profile):

Agentic Access Contract +10 pts — agentic_access artifact present (x-agentic-access), graded by author Ask about this →
Idempotency +9 pts — OpenAPI mutating operations declare an idempotency key — a header, a request-body property, or a named de-duplication token whose own description says so (verified); else common[].type matches /idempoten/i (documented) Ask about this →
A2A Agent Card +8 pts — a2a/-a2a.yml manifest, graded on conformance.grade against A2A 1.0.0 Ask about this →
Rate-Limit Signaling +7 pts — OpenAPI responses document X-RateLimit-* / RateLimit headers (verified), else a rate_limits artifact or RateLimits link (documented) Ask about this →
Request/Response Examples +7 pts — share of operations carrying request/response examples; else an Examples / Code Samples link Ask about this →
Typed Event Surface +6 pts — AsyncAPI document, OR webhooks/callbacks objects in the as-published OpenAPI, OR common[].type includes Webhooks Ask about this →

4 more unmet checks in the Agent Readiness table above.

Kin Score — facets with the most composite points still available (weight × headroom):

Contract Quality scores 16.5 — up to +20.9 composite points Ask about this →
Developer Ergonomics scores 25.6 — up to +14.9 composite points Ask about this →
Operational Transparency scores 0.0 — up to +13.0 composite points Ask about this →

Each check links to what satisfies it. Publish the artifact, or tell us where it already lives, and the score moves on the next scoring run.

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Markets this provider is in provisional

The Kin Score Market layer reads a provider inside its market: its position, and how deep its integrations go. Depth is only comparable within a position. Provisional and unweighted: not part of the Kin Score or agent readiness.

Market	Position	Depth	Registered MCP server	Declares compatibility
Cell & Gene Therapy	standard	17.2 (thin)	-	-
Clinical Trial Sponsors (drug pipelines)	standard	17.2 (thin)	-	-

Registered MCP server and declares compatibility are report only — not weighted. Undeclared means we found nothing we can read, so there is no number: we never infer integrations.

Standards implemented 5

Standards this provider implements or carries. De facto ones are profiled and measured by the API Commons; formal ones come from the standards directory and are linked by the provider's own tags. The evidence column says how each claim was established — not that it was made.

Model Context Protocol (MCP)

measured — observed by APIs.io (platform)

OAuth 2.0 Protected Resource Metadata

measured — observed by APIs.io (verified)

Dynamic Client Registration

measured — observed by APIs.io (published)

OpenAPI

measured — observed by APIs.io (published)

OAuth 2.0

measured — observed by APIs.io (declared)

APIs 2

Individual APIs this provider publishes, each with its own machine-readable definition.

A2 Biotherapeutics MCP API

Model Context Protocol servers exposed by the WordPress MCP adapter. Both servers require OAuth 2.1 bearer auth (observed HTTP 401 anonymously).

A2 Biotherapeutics Website (WordPress REST)

The public WordPress REST API (wp-json) of the A2 Biotherapeutics website at www.a2bio.com: the route index of the site's content management system, catalogued as one site surfa...

Open Collections 2

Open, tool-agnostic API collections (OpenAPI-derived and Bruno).

A2 Biotherapeutics WordPress REST MCP API

OPEN COLLECTION

API Collection

OPEN COLLECTION

MCP Servers 1

Model Context Protocol servers that expose these APIs to AI agents.

A2 Biotherapeutics MCP Server

A2 Biotherapeutics' corporate WordPress site exposes two live Model Context Protocol servers under the `mcp` REST namespace, guarded by an OAuth 2.1 authorization server the sam...

MCP SERVER

Agent Skills 2

Packaged agent skills for driving this provider's APIs from an AI assistant.

Discover the A2 Biotherapeutics API and MCP surface

AGENT SKILL

Read the A2 Biotherapeutics newsroom

AGENT SKILL

Terms of Service 1

What its API terms permit and prohibit, quoted from its own page.

A2 Biotherapeutics

9 quoted statements, read from A2 Biotherapeutics's own page on 2026-11-09.

TERMS

Privacy & Data 1

Its role, the data it processes, retention and transfers, quoted from its own privacy page.

A2 Biotherapeutics

13 quoted statements, read from A2 Biotherapeutics's own page on 2026-11-09.

PRIVACY

Eligibility 1

Who may sign up and where, quoted from its own terms.

A2 Biotherapeutics

2 quoted statements, read from A2 Biotherapeutics's own page on 2026-11-09.

ELIGIBILITY

Data License 1

How its data and outputs may be reused, quoted from its own terms.

A2 Biotherapeutics

1 quoted statement, read from A2 Biotherapeutics's own page on 2026-11-09.

LICENSE

Spectral Rules 1

Spectral governance rulesets for linting and validating these APIs. Counts are the severity each rule declares, not results of running them.

A2 Biotherapeutics API Rules

66 rules · 59 error-severity 6 warn-severity 1 info-severity

SPECTRAL

OpenAPI Overlays 3

Overlays applied on top of this provider's contracts. Each card says who wrote it: a document the provider publishes, or one API Evangelist derived or generated.

A2 Biotherapeutics Wp Abilities V1 Api Certification Overlay

2 actions · update · a2-biotherapeutics-wp-abilities-v1-api-openapi.yml

DERIVED

A2 Biotherapeutics Wp Rest Overlay

7 actions · security · a2-biotherapeutics-wp-rest-openapi.yml

DERIVED

A2 Biotherapeutics Wp V2 Api Certification Overlay

17 actions · update · a2-biotherapeutics-wp-v2-api-openapi.yml

DERIVED

Security Posture 2

Authentication, domain security, vulnerability disclosure, and trust-center signals.

A2 Biotherapeutics Authentication

apiKey/oauth2 · 2 schemes

SECURITY

A2 Biotherapeutics Domain Security

TLSv1.3 · HSTS · DMARC

SECURITY

Scopes 1

OAuth scopes governing access to this provider's APIs.

A2 Biotherapeutics Scopes

1 scope · authorizationCode

1 scopes

SCOPES

Resources

Agent Surfaces 4

MCP servers, agent skills, and machine-readable catalogs

MCPServer

AgentSkill

LLMsTxt

WellKnown

Design & Contract 5

Pagination, idempotency, versioning, errors, and events

Conventions

ErrorCatalog

DataModel

Lifecycle

Conformance

Build 1

SDKs, sample code, and the tooling you integrate with

ToolCrosswalk

ToolCrosswalk

Access & Security 4

Authentication, authorization, and security posture

Compliance

Authentication

OAuthScopes

DomainSecurity

Operate 1

Status, limits, changes, and where to get help

Contact

Contact

Commercial 4

Pricing, plans, and the legal terms of use

TermsOfService

PrivacyPolicy

UsageTerms

DataLicense

Company 6

The organization behind the API

Website

Newsroom

Blog

BlogRSS

Careers

Investors

Other 5

Properties that don't map to a standard resource type

SecondaryMarket

Overlay

ContentSignal

DataProcessing

Eligibility

Source (apis.yml)

aid: a2-biotherapeutics
name: A2 Biotherapeutics
description: A2 Biotherapeutics (A2 Bio) is a clinical-stage biotechnology company headquartered in Agoura Hills, California,
  founded in 2018 by Alexander Kamb, Michael Gallo and Paul Kang. It develops logic-gated cell therapies for solid tumors
  on its proprietary Tmod platform, a two-receptor activator/blocker design that lets an engineered T cell attack tumor cells
  which have lost an HLA allele while sparing normal cells that retain it. A2 Bio operates no developer API programme and
  publishes no product, clinical or research API. It is catalogued here because its corporate website runs a live WordPress
  REST API with 298 discoverable routes, and because that same install exposes two Model Context Protocol servers guarded
  by an OAuth 2.1 authorization server the host advertises through RFC 8414 and RFC 9728 metadata.
deliveryModel:
  model: saas
  open_source: false
  commercial: true
  callable_host: true
  label: Hosted service · you call their endpoint
  confidence: high
  source:
  - openapi
  - pricing
  generated: '2026-08-28'
  method: derived
accessModel:
  pricing: unknown
  onboarding: unknown
  trial: false
  try_now: false
  public: false
  gated_conflict: 'x-api-posture: private but 2 published API entries'
  label: Unknown
  confidence: low
  source:
  - authentication
  - security
  generated: '2026-11-13'
  method: derived
image: https://www.a2bio.com/wp-content/uploads/A2-Bio-Email-Logo-200-x-200.jpg
url: https://raw.githubusercontent.com/api-evangelist/a2-biotherapeutics/refs/heads/main/apis.yml
x-api-posture: no-product-api
x-api-posture-basis: observed
x-api-posture-note: A2 Bio operates no developer API programme and publishes no product, clinical or research API.
x-type: company
x-source: harvest:secondary-market
x-tier: enriched
x-tier-reason: enrichment pass 2026-08-02
specificationVersion: '0.23'
created: '2026-08-02'
modified: '2026-08-02'
tags:
- Company
- Biotechnology
- Life Sciences
- Cell Therapy
- Immuno-Oncology
- Oncology
- Pharmaceuticals
- Clinical Trials
- Healthcare
- MCP
- WordPress
tags_raw:
- Company
- Biotechnology
- Life Sciences
- Cell Therapy
- Immuno-Oncology
- Oncology
- Pharmaceuticals
- Clinical Trials
- Healthcare
- Model Context Protocol
- WordPress
apis:
- aid: a2-biotherapeutics:a2-biotherapeutics-mcp-api
  name: A2 Biotherapeutics MCP API
  description: Model Context Protocol servers exposed by the WordPress MCP adapter. Both servers require OAuth 2.1 bearer
    auth (observed HTTP 401 anonymously).
  humanURL: https://www.a2bio.com/wp-json/
  baseURL: https://www.a2bio.com/wp-json/
  tags:
  - MCP
  tags_raw:
  - mcp
  properties:
  - type: OpenAPI
    url: openapi/a2-biotherapeutics-mcp-api-openapi.yml
  - type: ToolCrosswalk
    url: mcp/a2-biotherapeutics-tool-crosswalk.yml
  - type: DataModel
    url: data-model/a2-biotherapeutics-data-model.yml
  x-surface: platform-generated
  x-platform: wordpress
  x-platform-surface: rest
- aid: a2-biotherapeutics:a2bio-com-website-wordpress-rest
  name: A2 Biotherapeutics Website (WordPress REST)
  description: 'The public WordPress REST API (wp-json) of the A2 Biotherapeutics website at www.a2bio.com: the route index
    of the site''s content management system, catalogued as one site surface rather than as separate APIs.'
  baseURL: https://www.a2bio.com/wp-json
  tags:
  - WordPress
  x-surface: platform-generated
  properties:
  - type: Documentation
    url: https://www.a2bio.com/wp-json
  x-platform: wordpress
  x-platform-surface: rest
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: Website
  url: https://www.a2bio.com/
- type: Newsroom
  url: https://www.a2bio.com/newsroom/
- type: Blog
  url: https://www.a2bio.com/newsroom/
- type: BlogRSS
  url: https://www.a2bio.com/feed/
- type: Careers
  url: https://www.a2bio.com/careers/
- type: Investors
  url: https://www.a2bio.com/about-us/investors/
- type: Contact
  url: https://www.a2bio.com/contact-us/
- type: TermsOfService
  url: https://www.a2bio.com/terms-of-use/
- type: PrivacyPolicy
  url: https://www.a2bio.com/privacy-policy/
- type: Compliance
  url: https://www.a2bio.com/california-compliance/
- type: SecondaryMarket
  url: https://forgeglobal.com/a2-biotherapeutics_stock/
- type: Overlay
  url: overlays/a2-biotherapeutics-wp-rest-overlay.yaml
- type: MCPServer
  url: mcp/a2-biotherapeutics-mcp.yml
- type: ToolCrosswalk
  url: mcp/a2-biotherapeutics-tool-crosswalk.yml
- type: AgentSkill
  url: skills/_index.yml
- type: LLMsTxt
  url: llms/a2-biotherapeutics-llms.txt
- type: WellKnown
  url: well-known/a2-biotherapeutics-well-known.yml
- type: ContentSignal
  url: well-known/a2-biotherapeutics-robots.txt
- type: Authentication
  url: authentication/a2-biotherapeutics-authentication.yml
- type: OAuthScopes
  url: scopes/a2-biotherapeutics-scopes.yml
- type: Conventions
  url: conventions/a2-biotherapeutics-conventions.yml
- type: ErrorCatalog
  url: errors/a2-biotherapeutics-problem-types.yml
- type: DataModel
  url: data-model/a2-biotherapeutics-data-model.yml
- type: Lifecycle
  url: lifecycle/a2-biotherapeutics-lifecycle.yml
- type: Conformance
  url: conformance/a2-biotherapeutics-conformance.yml
- type: DomainSecurity
  url: security/a2-biotherapeutics-domain-security.yml
- type: UsageTerms
  url: terms/a2-biotherapeutics-terms-of-service.yml
- type: DataProcessing
  url: privacy/a2-biotherapeutics-privacy-policy.yml
- type: Eligibility
  url: eligibility/a2-biotherapeutics-eligibility.yml
- type: DataLicense
  url: data-license/a2-biotherapeutics-data-license.yml
x-enrichment:
  date: '2026-08-02'
  status: enriched
  artifacts_added: 21
  pass: local-v1
x-enrichment-notes: 'Deliberately absent, each a verified negative on 2026-08-02: Idempotency (no idempotency contract exists
  on this surface), SDKs/Packages (nothing first-party on npm, PyPI or any registry), StatusPage (status.a2bio.com NXDOMAIN),
  Deprecation (no policy, no RFC 8594 headers), Security and SecurityTxt (/.well-known/security.txt 404, no disclosure page,
  no bug bounty), TrustCenter (trust.a2bio.com NXDOMAIN, no security certifications published), AgentCard (/.well-known/agent-card.json
  and /.well-known/agent.json both 404), AsyncAPI and Webhooks (no event surface), GitHubOrganization (github.com/A2Bio exists
  but carries no attribution to this company, so it is not claimed), Postman, Pricing, SignUp, Roadmap, Documentation, DeveloperPortal,
  APIReference, GettingStarted, Support, CLI, Sandbox and Components. The Compliance pointer is the company''s published pharmaceutical
  regulatory compliance declaration, not a security attestation.'

A2 Biotherapeutics API — frequently asked questions

Does A2 Biotherapeutics have an API?

Yes. APIs.io lists 2 APIs from A2 Biotherapeutics, including A2 Biotherapeutics MCP API and A2 Biotherapeutics Website (WordPress REST).

Is there an OpenAPI specification for the A2 Biotherapeutics API?

Yes. APIs.io indexes 1 OpenAPI specification for A2 Biotherapeutics, each linked for download from this page.

How do I authenticate with the A2 Biotherapeutics API?

A2 Biotherapeutics documents its authentication (apiKey/oauth2 · 2 schemes). The details are profiled on APIs.io as A2 Biotherapeutics Authentication.

Does A2 Biotherapeutics have an MCP server?

Yes. APIs.io lists 1 MCP server for A2 Biotherapeutics: A2 Biotherapeutics' corporate WordPress site exposes two live Model Context Protocol servers under the `mcp` REST namespace, guarded by an OAuth 2.1 authorization server the same host advertises via R

Is the A2 Biotherapeutics API ready for AI agents?

A2 Biotherapeutics has a Kin Score of 27.1 out of 100 (thin) and an Agent Readiness score of 43.8 (agent-ready), scored by API Evangelist on 2026-11-13.

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