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United States National Library of Medicine

The United States National Library of Medicine (NLM) is the world's largest biomedical library. It serves as a vital resource for researchers, healthcare professionals, and the general public by providing access to a vast collection of biomedical literature and resources. The NLM offers a wide range of services and resources including online databases, digital archives, and research tools that support medical research, education, and patient care. Key APIs include the NCBI E-Utilities (PubMed, Entrez), NCBI Datasets (genomes, genes), BLAST sequence alignment, and the ClinicalTrials.gov API.

4 APIs 0 Features
Federal GovernmentBiomedical ResearchHealthcareGenomicsLiterature

APIs

NCBI E-Utilities API

The NCBI E-Utilities (Entrez Programming Utilities) are the public API to the NCBI Entrez system providing access to all Entrez databases including PubMed (biomedical literature...

NCBI Datasets REST API

The NCBI Datasets REST API v2 provides programmatic access to biological data including genome assemblies, gene records, and protein sequences across organisms. Returns data pac...

NCBI BLAST URL API

The NCBI BLAST URL API allows developers to submit BLAST (Basic Local Alignment Search Tool) sequence searches for processing at NCBI using HTTPS. Supports nucleotide and protei...

ClinicalTrials.gov API

The ClinicalTrials.gov API provides programmatic access to clinical trial data registered with ClinicalTrials.gov, operated by the National Library of Medicine. Returns study in...

Collections

NCBI BLAST URL API

OPEN

NCBI Datasets REST API

OPEN

NCBI E-Utilities API

OPEN

ClinicalTrials.gov API

OPEN

Pricing Plans

United States National Library Of Medicine Plans Pricing

3 plans

PLANS

Rate Limits

United States National Library Of Medicine Rate Limits

5 limits

RATE LIMITS

FinOps

United States National Library Of Medicine Finops

FINOPS

Semantic Vocabularies

United States National Library Of Medicine Context

4 classes · 19 properties

JSON-LD

API Governance Rules

United States National Library of Medicine API Rules

7 rules · 3 errors 4 warnings

SPECTRAL

JSON Structure

Ncbi Pubmed Article Structure

0 properties

JSON STRUCTURE

Example Payloads

Ncbi Datasets Get Genome Example

3 fields

EXAMPLE

Ncbi Esearch Pubmed Example

3 fields

EXAMPLE

Nlm Clinicaltrials Search Example

3 fields

EXAMPLE

Resources

🔗
LinkedIn
LinkedIn
🌐
Portal
Portal

Sources

Raw ↑ 
opencollection: 1.0.0
info:
  name: ClinicalTrials.gov API
  version: 2.0.0
items:
- info:
    name: Studies
    type: folder
  items:
  - info:
      name: Search Clinical Trial Studies
      type: http
    http:
      method: GET
      url: https://clinicaltrials.gov/api/v2/studies
      params:
      - name: query.term
        value: diabetes type 2
        type: query
        description: Full-text search query term
      - name: query.cond
        value: Type 2 Diabetes
        type: query
        description: Condition or disease filter
      - name: query.intr
        value: metformin
        type: query
        description: Intervention or treatment filter
      - name: query.spons
        value: ''
        type: query
        description: Sponsor or collaborator filter
      - name: query.lead
        value: ''
        type: query
        description: Lead sponsor filter
      - name: filter.overallStatus
        value: ''
        type: query
        description: Trial overall status filter
      - name: filter.phase
        value: ''
        type: query
        description: Clinical trial phase filter
      - name: filter.studyType
        value: ''
        type: query
        description: Study type filter
      - name: filter.advanced
        value: ''
        type: query
        description: Advanced filter using Essie expression syntax
      - name: pageSize
        value: ''
        type: query
        description: Number of results per page (max 1000)
      - name: pageToken
        value: ''
        type: query
        description: Token for fetching the next page of results
      - name: fields
        value: ''
        type: query
        description: Comma-separated list of fields to return
      - name: sort
        value: ''
        type: query
        description: Sort order (e.g. @relevance, LastUpdatePostDate:desc)
      - name: format
        value: ''
        type: query
        description: Response format
    docs: Search and filter clinical trials registered on ClinicalTrials.gov. Supports full-text search, filtering by status,
      phase, condition, intervention type, sponsor, location, and more. Returns paginated results.
  - info:
      name: Get Study by NCT ID
      type: http
    http:
      method: GET
      url: https://clinicaltrials.gov/api/v2/studies/:nctId
      params:
      - name: nctId
        value: NCT04000009
        type: path
        description: ClinicalTrials.gov NCT identifier (e.g. NCT04000009)
      - name: fields
        value: ''
        type: query
        description: Comma-separated list of fields to return
      - name: format
        value: ''
        type: query
    docs: Retrieve complete study information for a specific clinical trial by its NCT (ClinicalTrials.gov) identifier.
- info:
    name: Metadata
    type: folder
  items:
  - info:
      name: Get Dataset Size
      type: http
    http:
      method: GET
      url: https://clinicaltrials.gov/api/v2/stats/size
      params:
      - name: query.cond
        value: ''
        type: query
      - name: filter.overallStatus
        value: ''
        type: query
    docs: Returns the total number of clinical trials in the ClinicalTrials.gov database, optionally filtered by query parameters.
  - info:
      name: Get Study Fields Metadata
      type: http
    http:
      method: GET
      url: https://clinicaltrials.gov/api/v2/studies/metadata
    docs: Retrieve metadata about all available data fields in the ClinicalTrials.gov study record, including field names,
      types, and descriptions.
bundled: true