Tune Therapeutics

aid: tune-therapeutics
name: Tune Therapeutics
description: Tune Therapeutics is a clinical-stage epigenetic editing biotechnology company headquartered in Durham, North
  Carolina with a second site in Seattle, Washington. Founded in 2021 by Charles Gersbach, Fyodor Urnov and Dan McHugh, the
  company develops its TEMPO platform for tunable epigenome editing — programmable DNA-binding modulation of gene expression
  that does not cut or permanently alter the underlying DNA sequence. Its lead program, TUNE-401, is an investigational epigenetic
  silencing therapy for chronic hepatitis B cleared by New Zealand Medsafe for a Phase 1b trial. Tune publishes no product
  API and operates no developer program; the only machine-readable surface it exposes is the WordPress REST API and a pair
  of OAuth-gated Model Context Protocol servers shipped by plugins on its corporate marketing site.
url: https://raw.githubusercontent.com/api-evangelist/tune-therapeutics/refs/heads/main/apis.yml
deliveryModel:
  model: saas
  open_source: false
  commercial: true
  callable_host: false
  label: Hosted service · you call their endpoint
  confidence: medium
  source:
  - pricing
  generated: '2026-08-28'
  method: derived
accessModel:
  pricing: unknown
  onboarding: unknown
  trial: false
  try_now: false
  public: false
  label: Unknown
  confidence: low
  probe_state: covered
  source:
  - authentication
  - scopes
  - security
  generated: '2026-11-06'
  method: derived
image: https://tunetx.com/wp-content/uploads/2022/10/TuneTx_Meta.png
x-type: company
x-source: harvest:secondary-market
x-tier: profiled
x-tier-reason: enrichment
specificationVersion: '0.23'
created: '2026-08-05'
modified: '2026-08-05'
tags:
- Company
- Biotechnology
- Life Sciences
- Therapeutics
- Genomics
- Epigenetics
- Gene Therapy
- Clinical Stage
- Research
apis:
- aid: tune-therapeutics:website-mcp
  name: Tune Therapeutics Website MCP Server
  description: 'Two Model Context Protocol servers exposed from the Tune Therapeutics corporate WordPress site via the WordPress
    MCP Adapter plugin, backed by the WordPress Abilities API. Both endpoints are live and answer JSON-RPC over HTTP, and
    both are protected: an unauthenticated tools/list returns HTTP 401 with a spec-conformant WWW-Authenticate Bearer challenge
    pointing at RFC 9728 protected-resource metadata. Discovery metadata (RFC 8414 authorization-server, RFC 9728 protected-resource)
    is served anonymously and was captured verbatim. This is a content-management-platform surface, not a first-party Tune
    Therapeutics product API — recorded because it is a real, live, agent-reachable endpoint on the company domain, not because
    the company markets it.'
  humanURL: https://tunetx.com/
  baseURL: https://tunetx.com/wp-json/mcp/
  tags:
  - MCP
  - OAuth
  - WordPress
  - Authentication
  tags_raw:
  - MCP
  - Model Context Protocol
  - OAuth
  - WordPress
  - Authentication
  x-origin: platform-default
  x-origin-note: Provided by the WordPress MCP Adapter plugin, not authored or marketed by Tune Therapeutics.
  properties:
  - type: MCPServer
    url: mcp/tune-therapeutics-mcp.yml
  - type: Authentication
    url: authentication/tune-therapeutics-authentication.yml
  - type: OAuthScopes
    url: scopes/tune-therapeutics-scopes.yml
  x-surface: platform-generated
  x-platform: wordpress
  x-platform-surface: mcp-plugin
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: DomainSecurity
  url: security/tune-therapeutics-domain-security.yml
- type: Website
  url: https://tunetx.com/
- type: Blog
  url: https://tunetx.com/news-and-insights/
- type: BlogRSS
  url: https://tunetx.com/feed/
- type: Support
  url: https://tunetx.com/contact-us/
- type: TermsOfService
  url: https://tunetx.com/terms-and-conditions/
- type: PrivacyPolicy
  url: https://tunetx.com/privacy-policy/
- type: WellKnown
  url: well-known/tune-therapeutics-well-known.yml
- type: MCPServer
  url: mcp/tune-therapeutics-mcp.yml
- type: Authentication
  url: authentication/tune-therapeutics-authentication.yml
- type: OAuthScopes
  url: scopes/tune-therapeutics-scopes.yml
- type: Conformance
  url: conformance/tune-therapeutics-conformance.yml
- type: LLMsTxt
  url: llms/tune-therapeutics-llms.txt
x-enrichment:
  date: '2026-08-05'
  status: enriched
  artifacts_added: 10
  pass: local-v1
x-coverage:
  state: covered
  reason: platform-surface-only
  detail: Tune Therapeutics is a clinical-stage biotech with no product API and no developer program — /openapi.json, /swagger.json,
    /api-docs, /graphql, /docs and /developers all 404 and no api./docs./developer. subdomain resolves — but its corporate
    WordPress site exposes two live OAuth 2.1-gated Model Context Protocol servers under /wp-json/mcp/ with RFC 8414 and RFC
    9728 discovery metadata served anonymously, which is what this profile captures.
  evidence:
  - url: https://tunetx.com/openapi.json
    status: 404
  - url: https://tunetx.com/.well-known/oauth-protected-resource
    status: 200
  - url: https://tunetx.com/wp-json/mcp
    status: 200
  - url: https://tunetx.com/wp-json/mcp/mcp-oauth-server
    status: 401
  - url: https://tunetx.com/.well-known/agent-card.json
    status: 404
  checked: '2026-08-05'