Syapse

Syapse was a San Francisco precision-medicine software company, founded in 2008, that built a real-world evidence platform for community oncology. Its product integrated structured clinical data from health-system EHRs with genomic/NGS results to support molecular tumor boards, care coordination, quality improvement and life-sciences research, and it ran the Syapse Learning Health Network of community health systems alongside collaborations with Roche, Amgen and the US Department of Veterans Affairs. Syapse Holdings was acquired by N-Power Medicine in a stock-for-stock exchange that closed 2024-12-30 and was announced 2025-01-12; its network of 1,000+ community oncologists, its data and technology stack, and its team were folded into N-Power Medicine's always-on community clinical-research model. The Syapse brand has since been fully retired: syapse.com now serves nothing but a 292-byte meta-refresh stub redirecting to npowermedicine.com, dated 2025-01-12. Syapse never published a public developer program, and no public API, OpenAPI/AsyncAPI/GraphQL contract, SDK or developer portal survives.

Syapse is profiled on the APIs.io network. Tagged areas include Company, Healthcare, Oncology, Precision Medicine, and Real-World Evidence.

🌐 Visit website 📡 Source on GitHub

4.0/100 minimal ▬ flat Agent 0/100 human only Full breakdown ↓
scored 2026-09-25 · rubric v0.23.0

0 APIs

Company Healthcare Oncology Precision Medicine Real-World Evidence Clinical Research Health Data Life Sciences Acquired

Kin Score

Kin Score How this is scored →
scored 2026-09-25 · rubric v0.23.0

Composite quality — 4.0/100 · minimal

Contract Quality 0.0 / 21

Developer Ergonomics 0.0 / 17

Access Clarity 0.0 / 17

Operational Transparency 0.3 / 11

Contract Governance 0.0 / 10

Discoverability 4.1 / 9

Regulatory Posture 0.7 / 15

Agent readiness — 0/100 · human only

Machine-Readable Contract 0 / 18

Agentic Access Contract 0 / 10

Documented Reversibility 0 / 6

MCP Server 0 / 12

Machine-Readable Auth 0 / 10

Idempotency 0 / 9

Stable Error Semantics 0 / 8

Request/Response Examples 0 / 7

Rate-Limit Signaling 0 / 7

Typed Event Surface 0 / 6

Agent Skills 0 / 5

Well-Known Catalog 0 / 4

Consent & Bot Identity 0 / 3

A2A Agent Card 0 / 8

Dry-Run / Simulate Mode 0 / 4

Delegated User Identity 0 / 6

Protected Resource Metadata 0 / 5

Registration Without a Human 0 / 6

Agentic Commerce Well-Known Document 0 / 5

Regulatory Posture applies to this provider. Its tags matched the Health regime, so Regulatory Posture carries 15 points of the composite. If this regime is wrong for your business, say so on your provider repo — the applicability map is public and we will correct it.

Create-or-Update Ergonomics could not be measured. We hold no machine-readable contract for this provider to read, so there is nothing to measure a write surface against. Excluded rather than scored zero: never-measured and measured-empty are different facts. Publishing an OpenAPI is what makes this facet — and several others — scorable at all.

The six quality facets above are damped to 85 points between them, because the conditional facet above carries the other 15. That is why each facet's contribution is shown against a damped maximum: raising a quality facet moves the composite by 85% of its nominal weight, not 100%. The full arithmetic is at apis.io/rating/.

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Security Posture 1

Authentication, domain security, vulnerability disclosure, and trust-center signals.

Syapse Domain Security

TLSv1.3 · DMARC

SECURITY

Resources

Build 2

SDKs, sample code, and the tooling you integrate with

GitHubOrganization

GitHubOrganization

Packages

Packages

Access & Security 1

Authentication, authorization, and security posture

DomainSecurity

DomainSecurity

Company 1

The organization behind the API

Website

Website

Source (apis.yml)

aid: syapse
name: Syapse
description: 'Syapse was a San Francisco precision-medicine software company, founded in 2008, that built a real-world evidence
  platform for community oncology. Its product integrated structured clinical data from health-system EHRs with genomic/NGS
  results to support molecular tumor boards, care coordination, quality improvement and life-sciences research, and it ran
  the Syapse Learning Health Network of community health systems alongside collaborations with Roche, Amgen and the US Department
  of Veterans Affairs. Syapse Holdings was acquired by N-Power Medicine in a stock-for-stock exchange that closed 2024-12-30
  and was announced 2025-01-12; its network of 1,000+ community oncologists, its data and technology stack, and its team were
  folded into N-Power Medicine''s always-on community clinical-research model. The Syapse brand has since been fully retired:
  syapse.com now serves nothing but a 292-byte meta-refresh stub redirecting to npowermedicine.com, dated 2025-01-12. Syapse
  never published a public developer program, and no public API, OpenAPI/AsyncAPI/GraphQL contract, SDK or developer portal
  survives.'
accessModel:
  pricing: unknown
  onboarding: unknown
  trial: false
  try_now: false
  public: false
  label: Unknown
  confidence: low
  source:
  - security
  generated: '2026-09-02'
  method: derived
image: https://avatars.githubusercontent.com/u/1268822?v=4
url: https://raw.githubusercontent.com/api-evangelist/syapse/refs/heads/main/apis.yml
x-api-posture: no-product-api
x-api-posture-basis: observed
x-api-posture-note: Syapse never published a public developer program, and no public API, OpenAPI/AsyncAPI/GraphQL contract,
  SDK or developer portal survives.
x-type: company
x-source: harvest:secondary-market
x-tier: stub
x-tier-reason: harvest
x-parent-company: n-power-medicine
specificationVersion: '0.20'
created: '2026-08-29'
modified: '2026-08-29'
tags:
- Company
- Healthcare
- Oncology
- Precision Medicine
- Real-World Evidence
- Clinical Research
- Health Data
- Life Sciences
- Acquired
apis: []
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: DomainSecurity
  url: security/syapse-domain-security.yml
- type: Website
  url: https://syapse.com/
- type: GitHubOrganization
  url: https://github.com/syapse
- type: Packages
  url: packages/syapse-packages.yml
x-enrichment:
  date: '2026-08-29'
  status: minimal
  artifacts_added: 3
  pass: local-v1
x-coverage:
  state: none
  reason: defunct
  detail: 'Syapse was fully absorbed into N-Power Medicine (stock-for-stock, closed 2024-12-30) and its entire web property
    was retired the same week: syapse.com and www.syapse.com now answer every path — including an invented control path —
    with the identical 292-byte HTML meta-refresh stub to npowermedicine.com, Last-Modified 2025-01-12, so there is no docs
    host, no API host and no contract left to read.'
  evidence:
  - url: https://syapse.com/
    status: 200
  - url: https://syapse.com/this-path-does-not-exist-9f3a
    status: 200
  - url: https://syapse.com/openapi.json
    status: 200
  - url: https://www.syapse.com/.well-known/security.txt
    status: 200
  - url: https://www.npowermedicine.com/openapi.json
    status: 404
  checked: '2026-08-29'

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