Syapse

Syapse was a San Francisco precision-medicine software company, founded in 2008, that built a real-world evidence platform for community oncology. Its product integrated structured clinical data from health-system EHRs with genomic/NGS results to support molecular tumor boards, care coordination, quality improvement and life-sciences research, and it ran the Syapse Learning Health Network of community health systems alongside collaborations with Roche, Amgen and the US Department of Veterans Affairs. Syapse Holdings was acquired by N-Power Medicine in a stock-for-stock exchange that closed 2024-12-30 and was announced 2025-01-12; its network of 1,000+ community oncologists, its data and technology stack, and its team were folded into N-Power Medicine's always-on community clinical-research model. The Syapse brand has since been fully retired: syapse.com now serves nothing but a 292-byte meta-refresh stub redirecting to npowermedicine.com, dated 2025-01-12. Syapse never published a public developer program, and no public API, OpenAPI/AsyncAPI/GraphQL contract, SDK or developer portal survives.

Syapse is profiled on the APIs.io network. Tagged areas include Company, Healthcare, Oncology, Precision Medicine, and Real-World Evidence.

🌐 Visit website 📡 Profile data on GitHub

4.0/100 minimal ▬ flat Agent 0/100 human only Full breakdown ↓
scored 2026-11-06 · rubric v0.27.0 · Show this score on your site →

AccessNo public API

0 APIs

Company Healthcare Oncology Precision Medicine Real-World Evidence Clinical Research Health Data Life Sciences Acquired

Kin Score

Kin Score How this is scored →
scored 2026-11-06 · rubric v0.27.0

Composite quality — 4.0/100 · minimal

Contract Quality 0.0 / 21

Developer Ergonomics 0.0 / 17

Access Clarity 0.0 / 17

Operational Transparency 0.3 / 11

Contract Governance 0.0 / 10

Discoverability 4.1 / 9

Regulatory Posture 0.7 / 15

Agent readiness — 0/100 · human only

Machine-Readable Contract 0 / 18

Agentic Access Contract 0 / 10

Documented Reversibility 0 / 6

MCP Server 0 / 12

Machine-Readable Auth 0 / 10

Idempotency 0 / 9

Stable Error Semantics 0 / 8

Request/Response Examples 0 / 7

Rate-Limit Signaling 0 / 7

Typed Event Surface 0 / 6

Agent Skills 0 / 5

Well-Known Catalog 0 / 4

Consent & Bot Identity 0 / 3

A2A Agent Card 0 / 8

Dry-Run / Simulate Mode 0 / 4

Delegated User Identity 0 / 6

Protected Resource Metadata 0 / 5

Registration Without a Human 0 / 6

Agentic Commerce Well-Known Document 0 / 5

Pagination 5 / 5

Distinct Operations 3 / 3

MCP Tool Quality 6 / 6

Regulatory Posture applies to this provider. Its tags matched the Health regime, so Regulatory Posture carries 15 points of the composite. If this regime is wrong for your business, say so on your provider repo — the applicability map is public and we will correct it.

Create-or-Update Ergonomics could not be measured. We hold no machine-readable contract for this provider to read, so there is nothing to measure a write surface against. Excluded rather than scored zero: never-measured and measured-empty are different facts. Publishing an OpenAPI is what makes this facet — and several others — scorable at all.

The six quality facets above are damped to 85 points between them, because the conditional facet above carries the other 15. That is why each facet's contribution is shown against a damped maximum: raising a quality facet moves the composite by 85% of its nominal weight, not 100%. The full arithmetic is at apis.io/rating/.

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Agent readiness — checks not met, largest first (exact, from this profile):

Machine-Readable Contract +18 pts — api_specs includes an OpenAPI document
MCP Server +12 pts — deployment.mode + probe verdict on the mcp/ manifest, not the pointer; an unprobed slug falls back to authorship
Agentic Access Contract +10 pts — agentic_access artifact present (x-agentic-access), graded by author
Machine-Readable Auth +10 pts — a served openid-configuration/oauth-authorization-server carrying `issuer` (served), else the securitySchemes class in the provider OpenAPIs — bound (mutualTLS, DPoP, Signature) > negotiable (oauth2 authorizationCode/clientCredentials, openIdConnect) > bearer (http bearer, apiKey)
Idempotency +9 pts — OpenAPI mutating operations declare an idempotency key — a header, a request-body property, or a named de-duplication token whose own description says so (verified); else common[].type matches /idempoten/i (documented)
Stable Error Semantics +8 pts — OpenAPI $refs a shared error schema across 4xx/5xx responses (verified), else common[].type includes ErrorCatalog / ErrorCodes / DeclineCodes

13 more unmet checks in the Agent Readiness table above.

Kin Score — facets with the most composite points still available (weight × headroom):

Contract Quality scores 0.0 — up to +25.0 composite points
Developer Ergonomics scores 0.0 — up to +20.0 composite points
Access Clarity scores 0.0 — up to +20.0 composite points

Each check links to what satisfies it. Publish the artifact, or tell us where it already lives, and the score moves on the next scoring run.

Improve this rating by publishing the missing artifacts — every area above can be raised, and the full rubric is at apis.io/rating/. Every facet and dimension name above is a link: it opens that measurement's own page — what it means, the exact checks that feed it, how the whole catalog distributes on it, and the providers at the top of it. This rating is computed from the provider profile at artifacts.apis.io/syapse/apis.yml: open an issue on github.com/api-evangelist/syapse to ask a question or point us at an artifact you publish. Submit an artifact on GitHub — free → Manage your own listing — the Influence plan, $499/mo →

Markets this provider is in provisional

The Kin Score Market layer reads a provider inside its market: its position, and how deep its integrations go. Depth is only comparable within a position. Provisional and unweighted: not part of the Kin Score or agent readiness.

Market	Position	Depth	Registered MCP server	Declares compatibility
GA4GH Genomics Standards (htsget, DRS, TES, WES, Beacon, Passports)	standard	17.2 (thin)	-	-

Registered MCP server and declares compatibility are report only — not weighted. Undeclared means we found nothing we can read, so there is no number: we never infer integrations.

Security Posture 1

Authentication, domain security, vulnerability disclosure, and trust-center signals.

Syapse Domain Security

TLSv1.3 · DMARC

SECURITY

Resources

Build 2

SDKs, sample code, and the tooling you integrate with

GitHubOrganization

GitHubOrganization

Packages

Packages

Access & Security 1

Authentication, authorization, and security posture

DomainSecurity

DomainSecurity

Company 1

The organization behind the API

Website

Website

Source (apis.yml)

aid: syapse
name: Syapse
description: 'Syapse was a San Francisco precision-medicine software company, founded in 2008, that built a real-world evidence
  platform for community oncology. Its product integrated structured clinical data from health-system EHRs with genomic/NGS
  results to support molecular tumor boards, care coordination, quality improvement and life-sciences research, and it ran
  the Syapse Learning Health Network of community health systems alongside collaborations with Roche, Amgen and the US Department
  of Veterans Affairs. Syapse Holdings was acquired by N-Power Medicine in a stock-for-stock exchange that closed 2024-12-30
  and was announced 2025-01-12; its network of 1,000+ community oncologists, its data and technology stack, and its team were
  folded into N-Power Medicine''s always-on community clinical-research model. The Syapse brand has since been fully retired:
  syapse.com now serves nothing but a 292-byte meta-refresh stub redirecting to npowermedicine.com, dated 2025-01-12. Syapse
  never published a public developer program, and no public API, OpenAPI/AsyncAPI/GraphQL contract, SDK or developer portal
  survives.'
accessModel:
  pricing: unknown
  onboarding: unknown
  trial: false
  try_now: false
  public: false
  gated: private
  gated_source:
  - x-api-posture
  label: Unknown
  confidence: low
  probe_state: none
  source:
  - security
  generated: '2026-11-06'
  method: derived
image: https://avatars.githubusercontent.com/u/1268822?v=4
url: https://raw.githubusercontent.com/api-evangelist/syapse/refs/heads/main/apis.yml
x-api-posture: no-product-api
x-api-posture-basis: observed
x-api-posture-note: Syapse never published a public developer program, and no public API, OpenAPI/AsyncAPI/GraphQL contract,
  SDK or developer portal survives.
x-type: company
x-source: harvest:secondary-market
x-tier: stub
x-tier-reason: harvest
x-parent-company: n-power-medicine
specificationVersion: '0.20'
created: '2026-08-29'
modified: '2026-08-29'
tags:
- Company
- Healthcare
- Oncology
- Precision Medicine
- Real-World Evidence
- Clinical Research
- Health Data
- Life Sciences
- Acquired
apis: []
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: DomainSecurity
  url: security/syapse-domain-security.yml
- type: Website
  url: https://syapse.com/
- type: GitHubOrganization
  url: https://github.com/syapse
- type: Packages
  url: packages/syapse-packages.yml
x-enrichment:
  date: '2026-08-29'
  status: minimal
  artifacts_added: 3
  pass: local-v1
x-coverage:
  state: none
  reason: defunct
  detail: 'Syapse was fully absorbed into N-Power Medicine (stock-for-stock, closed 2024-12-30) and its entire web property
    was retired the same week: syapse.com and www.syapse.com now answer every path — including an invented control path —
    with the identical 292-byte HTML meta-refresh stub to npowermedicine.com, Last-Modified 2025-01-12, so there is no docs
    host, no API host and no contract left to read.'
  evidence:
  - url: https://syapse.com/
    status: 200
  - url: https://syapse.com/this-path-does-not-exist-9f3a
    status: 200
  - url: https://syapse.com/openapi.json
    status: 200
  - url: https://www.syapse.com/.well-known/security.txt
    status: 200
  - url: https://www.npowermedicine.com/openapi.json
    status: 404
  checked: '2026-08-29'

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get_provider_artifactsEvery artifact this provider publishes, grouped by type.
get_provider_operationsEvery operation across all of their OpenAPIs — one call instead of parsing every spec.
get_provider_toolsEvery MCP tool they ship, with the operation each wraps.
get_provider_evidenceHow each part of their score was established. Free — the basis for a claim should not sit behind it.
get_provider_ratingPRO — composite, band, trend and facet scores.
apis_io_searchSTART HERE — APIs, providers and tags for one query, each with its total.
resolveTurn a domain, URL or GitHub org into the provider it belongs to.
find_cohortsEvery scored population of providers in the catalog.

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