SonoThera

aid: sonothera
name: SonoThera
description: 'SonoThera, Inc. is a privately held, clinical-stage biotechnology company headquartered at 201 Haskins Way in
  South San Francisco, California, founded in 2022 to make genetic medicine deliverable without a viral vector. Its RIPPLE
  platform pairs an intravenously administered lipid-and-microbubble formulation with an externally applied diagnostic ultrasound
  probe: the acoustic energy transiently permeabilizes cell membranes in the targeted organ so a nucleic-acid payload enters
  only where the probe is pointed, an approach built on the roughly 35 million ultrasound contrast-agent doses given safely
  each year in cardiac imaging. A companion payload engineering platform, PORE, carries DNA and RNA constructs, gene editing
  and gene silencing cargo of varied size and format. The company holds an exclusive license to GE HealthCare''s Optison and
  Sonazoid microbubble products for use with the platform, and has raised approximately $186 million — a $60.75 million Series
  A and an oversubscribed $125 million Series B — from ARCH Venture Partners, Johnson & Johnson, Illumina Ventures and Eli
  Lilly, to push lead programs in Duchenne muscular dystrophy and autosomal dominant polycystic kidney disease into the clinic,
  with preclinical work in Alport syndrome and hemophilia A. It was co-founded by Kenneth Greenberg (CEO), Steve Feinstein
  (Chief Scientific Officer) and Michael H. Davidson (Executive Chairman). SonoThera sells therapeutics, not software: it
  runs no developer program, publishes no API, SDK or machine-readable specification, and maintains no public source-code
  organization.'
url: https://raw.githubusercontent.com/api-evangelist/sonothera/refs/heads/main/apis.yml
x-type: company
x-source: harvest:secondary-market
x-tier: profiled
x-tier-reason: enrichment-pipeline
deliveryModel:
  model: unknown
  open_source: false
  commercial: false
  callable_host: false
  label: Delivery model not determined — needs a product licence on record
  confidence: low
  source:
  - none
  generated: '2026-08-28'
  method: derived
accessModel:
  pricing: unknown
  onboarding: unknown
  trial: false
  try_now: false
  public: false
  label: Unknown
  confidence: low
  source:
  - security
  generated: '2026-09-02'
  method: derived
specificationVersion: '0.20'
created: '2026-08-28'
modified: '2026-08-28'
tags:
- Company
- Biotechnology
- Pharmaceuticals
- Gene Therapy
- Genetic Medicine
- Drug Delivery
- Ultrasound
- Life Sciences
- Clinical Trials
- Rare Disease
apis: []
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: DomainSecurity
  url: security/sonothera-domain-security.yml
- type: Website
  url: https://sonothera.com/
- type: About
  url: https://sonothera.com/about-us/
- type: Research
  url: https://sonothera.com/science/
- type: News
  url: https://sonothera.com/news/
- type: Careers
  url: https://sonothera.com/careers/
- type: Contact
  url: https://sonothera.com/contact-us/
- type: Support
  url: https://sonothera.com/contact-us/
- type: LinkedIn
  url: https://www.linkedin.com/company/sonothera
- type: LLMsTxt
  url: llms/sonothera-llms.txt
x-enrichment:
  date: '2026-08-28'
  status: minimal
  artifacts_added: 3
  pass: local-v1
x-coverage:
  state: none
  reason: not-a-software-company
  detail: SonoThera is a clinical-stage, ultrasound-mediated gene therapy company founded in 2022 whose product is a preclinical
    drug pipeline (DMD and ADPKD), not software — sonothera.com is a seven-page WordPress marketing site on WP Engine with
    no developer, docs or API section, every contract-discovery path (/openapi.json, /swagger.json, /api-docs, /docs, /api,
    /developers) and every /.well-known/* path returns a real 404, api./dev./docs./developer./mcp..sonothera.com are NXDOMAIN
    rather than wildcarded, and api.github.com/orgs/sonothera 404s, so there is no organization, package or specification
    anywhere to harvest.
  evidence:
  - url: https://sonothera.com/
    status: 200
  - url: https://sonothera.com/openapi.json
    status: 404
  - url: https://sonothera.com/api-docs
    status: 404
  - url: https://sonothera.com/developers
    status: 404
  - url: https://sonothera.com/.well-known/security.txt
    status: 404
  - url: https://sonothera.com/.well-known/agent-card.json
    status: 404
  - url: https://sonothera.com/llms.txt
    status: 404
  - url: https://api.github.com/orgs/sonothera
    status: 404
  checked: '2026-08-28'