Sigma-Aldrich

Sigma-Aldrich was a leading life science and high technology company whose biochemical and organic chemical products, kits, and services are used in scientific research, including genomics, proteomics, and drug discovery. Acquired by Merck KGaA in 2015, Sigma-Aldrich now operates as part of MilliporeSigma in North America and Merck in other regions, continuing to provide the world's largest catalog of research chemicals, biochemicals, laboratory equipment, and life science products to researchers globally.

Sigma-Aldrich publishes 6 API contracts indexed on the APIs.io network, including Pricing and Availability API, Products API, Safety Data Sheets API, and 3 more. Tagged areas include Life Sciences, Chemistry, Biochemistry, Laboratory, and Research.

The Sigma-Aldrich catalog on APIs.io includes 1 JSON-LD context and 2 Spectral governance rulesets.

Sigma-Aldrich’s developer surface includes authentication and 11 more developer resources.

🌐 Visit website 📡 Profile data on GitHub

32.2/100 thin ▬ flat Agent 21/100 agent aware Full breakdown ↓
scored 2026-11-06 · rubric v0.27.0 · Show this score on your site →

AccessEnterprise

1 published contract

Life Sciences ChemistryBiochemistryLaboratory ResearchChemical Catalog

Kin Score

Kin Score How this is scored →
scored 2026-11-06 · rubric v0.27.0

Composite quality — 32.2/100 · thin

Contract Quality 12.9 / 21

Developer Ergonomics 5.3 / 17

Access Clarity 0.9 / 17

Operational Transparency 0.6 / 11

Contract Governance 2.8 / 10

Discoverability 4.9 / 9

Regulatory Posture 2.0 / 15

Agent readiness — 21/100 · agent aware

Machine-Readable Contract 18 / 18

Agentic Access Contract 10 / 10

Documented Reversibility 0 / 6

MCP Server 0 / 12

Machine-Readable Auth 10 / 10

Idempotency 0 / 9

Stable Error Semantics 0 / 8

Request/Response Examples 0 / 7

Rate-Limit Signaling 7 / 7

Typed Event Surface 0 / 6

Agent Skills 0 / 5

Well-Known Catalog 0 / 4

Consent & Bot Identity 0 / 3

A2A Agent Card 0 / 8

Dry-Run / Simulate Mode 0 / 4

Delegated User Identity 0 / 6

Protected Resource Metadata 0 / 5

Registration Without a Human 0 / 6

Agentic Commerce Well-Known Document 0 / 5

Pagination 5 / 5

Distinct Operations 3 / 3

MCP Tool Quality 6 / 6

Regulatory Posture applies to this provider. Its tags matched the Health regime, so Regulatory Posture carries 15 points of the composite. If this regime is wrong for your business, say so on your provider repo — the applicability map is public and we will correct it.

Create-or-Update Ergonomics does not apply to this provider. The published contracts declare no write operations, and a read-only API cannot create-or-update. The facet is excluded from this provider's denominator entirely — not scored zero. A reference or data API is not deficient for being unable to upsert.

The six quality facets above are damped to 85 points between them, because the conditional facet above carries the other 15. That is why each facet's contribution is shown against a damped maximum: raising a quality facet moves the composite by 85% of its nominal weight, not 100%. The full arithmetic is at apis.io/rating/.

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Agent readiness — checks not met, largest first (exact, from this profile):

MCP Server +12 pts — deployment.mode + probe verdict on the mcp/ manifest, not the pointer; an unprobed slug falls back to authorship
Idempotency +9 pts — OpenAPI mutating operations declare an idempotency key — a header, a request-body property, or a named de-duplication token whose own description says so (verified); else common[].type matches /idempoten/i (documented)
Stable Error Semantics +8 pts — OpenAPI $refs a shared error schema across 4xx/5xx responses (verified), else common[].type includes ErrorCatalog / ErrorCodes / DeclineCodes
A2A Agent Card +8 pts — a2a/-a2a.yml manifest, graded on conformance.grade against A2A 1.0.0
Request/Response Examples +7 pts — share of operations carrying request/response examples; else an Examples / Code Samples link
Registration Without a Human +6 pts — a `registration_endpoint` in the served RFC 8414 / OIDC discovery document

9 more unmet checks in the Agent Readiness table above.

Kin Score — facets with the most composite points still available (weight × headroom):

Access Clarity scores 5.3 — up to +18.9 composite points
Developer Ergonomics scores 31.0 — up to +13.8 composite points
Operational Transparency scores 5.3 — up to +12.3 composite points

Each check links to what satisfies it. Publish the artifact, or tell us where it already lives, and the score moves on the next scoring run.

Improve this rating by publishing the missing artifacts — every area above can be raised, and the full rubric is at apis.io/rating/. Every facet and dimension name above is a link: it opens that measurement's own page — what it means, the exact checks that feed it, how the whole catalog distributes on it, and the providers at the top of it. This rating is computed from the provider profile at artifacts.apis.io/sigma-aldrich/apis.yml: open an issue on github.com/api-evangelist/sigma-aldrich to ask a question or point us at an artifact you publish. Submit an artifact on GitHub — free → Manage your own listing — the Influence plan, $499/mo →

Markets this provider is in provisional

The Kin Score Market layer reads a provider inside its market: its position, and how deep its integrations go. Depth is only comparable within a position. Provisional and unweighted: not part of the Kin Score or agent readiness.

Market	Position	Depth	Registered MCP server	Declares compatibility
Chemistry and Materials (chemical data depositors, materials-data APIs)	standard	17.2 (thin)	-	-

Registered MCP server and declares compatibility are report only — not weighted. Undeclared means we found nothing we can read, so there is no number: we never infer integrations.

Standards implemented 1

Standards this provider implements or carries. De facto ones are profiled and measured by the API Commons; formal ones come from the standards directory and are linked by the provider's own tags. The evidence column says how each claim was established — not that it was made.

OpenAPI

measured — observed by APIs.io (published)

APIs 6

Individual APIs this provider publishes, each with its own machine-readable definition.

Sigma-Aldrich Chemical Structure Search API

The Sigma-Aldrich Chemical Structure Search API enables substructure, exact structure, and similarity searches against the Sigma-Aldrich chemical catalog using SMILES, InChI, or...

Sigma-Aldrich Safety Data Sheet API

The Safety Data Sheet (SDS) API provides programmatic access to GHS- compliant Safety Data Sheets for all Sigma-Aldrich chemical products. Enables EHS systems, LIMS platforms, a...

Sigma-Aldrich Pricing and Availability API

Real-time pricing and global stock availability for Sigma-Aldrich products.

Sigma-Aldrich Products API

Product catalog search and retrieval for research chemicals, biochemicals, and laboratory supplies.

Sigma-Aldrich Safety Data Sheets API

Retrieval of GHS-compliant Safety Data Sheets for regulatory compliance and laboratory safety management.

Sigma-Aldrich Structures API

Chemical structure search using SMILES, InChI, or molecular formula notation for cheminformatics workflows.

Open Collections 5

Open, tool-agnostic API collections (OpenAPI-derived and Bruno).

Sigma-Aldrich Product Search Pricing and Availability API

OPEN COLLECTION

Sigma-Aldrich Product Search API

OPEN COLLECTION

Sigma-Aldrich Product Search Pricing and Availability Products API

OPEN COLLECTION

Sigma-Aldrich Product Search Pricing and Availability Safety Data Sheets API

OPEN COLLECTION

Sigma-Aldrich Product Search Pricing and Availability Structures API

OPEN COLLECTION

Sigma-Aldrich API pricing

Not yet checked against Sigma-Aldrich's own pricing page. Compiled by API Evangelist on 2026-05-05 from www.sigmaaldrich.com/; confirm before you rely on a figure.

Plan	Price
Contact Sales enterprise	—

Plan details, limits and sources →

Rate limits

Contractual limit: see integration agreement varies

Compiled by API Evangelist, not yet checked against Sigma-Aldrich's documentation. Rate-limit details →

Pricing Plans 1

Published pricing tiers and plan structures.

Sigma Aldrich Plans Pricing

1 plans

PLANS

Rate Limits 1

Documented rate limits and quota policies.

Sigma Aldrich Rate Limits

1 limits

RATE LIMITS

Service Levels 1

Uptime the provider promises or reports, as SLA4OAI. Read from its own pages; APIs.io runs no monitors.

Sigma-Aldrich

SLA

FinOps 1

Cost, billing, and metering signals for API financial operations.

Sigma Aldrich Finops

FINOPS

Semantic Vocabularies 1

JSON-LD contexts and semantic vocabularies used across these APIs.

Sigma Aldrich Context

15 classes · 8 properties

JSON-LD

Spectral Rules 2

Spectral governance rulesets for linting and validating these APIs.

Sigma-Aldrich — jsonschema rules

5 rules · 3 warnings 2 info

SPECTRAL

Sigma-Aldrich API Rules

8 rules · 4 errors 4 warnings

SPECTRAL

JSON Schema 1

Standalone JSON Schema definitions for this provider's data models.

SigmaAldrichProduct

15 properties

JSON SCHEMA

JSON Structure 1

JSON Structure definitions describing this provider's data shapes.

Sigma Aldrich Product Structure

0 properties

JSON STRUCTURE

Examples 1

Example request and response payloads for these APIs.

Sigma Aldrich Search Products Example

2 fields

EXAMPLE

Security Posture 2

Authentication, domain security, vulnerability disclosure, and trust-center signals.

Sigma Aldrich Authentication

apiKey · 1 scheme

SECURITY

Sigma Aldrich Domain Security

TLSv1.3 · DMARC

SECURITY

Agentic Access 1

Recommended x-agentic-access execution contracts for AI agents.

Sigma Aldrich Agentic Access

6 operations

6 operations · 0 acting

AGENTIC

Press 5

Recent news and press coverage referencing this provider.

Sigma-Aldrich Stockholders Approve Acquisition By Merck ...

AIDDISON™: Using AI-Powered Software to Accelerate ...

Fast-Tracking Drug Discovery with an AI Boost

MilliporeSigma Launches First Ever AI Solution to Integrate ...

Sigma-Aldrich® and The Scripps Research Institute ...

Resources

Get Started 2

Portal, sign-up, and the first successful call

SDS Portal

SDS Portal

DeveloperPortal

DeveloperPortal

Agent Surfaces 1

MCP servers, agent skills, and machine-readable catalogs

AgenticAccess

AgenticAccess

Access & Security 2

Authentication, authorization, and security posture

DomainSecurity

DomainSecurity

Authentication

Authentication

Operate 1

Status, limits, changes, and where to get help

RateLimits

RateLimits

Commercial 2

Pricing, plans, and the legal terms of use

Plans

Plans

FinOps

FinOps

Company 2

The organization behind the API

LinkedIn

Website

Website

Other 2

Properties that don't map to a standard resource type

ProductCatalog

ProductCatalog

Parent Company

Parent Company

Source (apis.yml)

aid: sigma-aldrich
url: https://raw.githubusercontent.com/api-evangelist/sigma-aldrich/refs/heads/main/apis.yml
apis:
- aid: sigma-aldrich:sigma-aldrich-structure-search-api
  name: Sigma-Aldrich Chemical Structure Search API
  tags:
  - Chemistry
  - Cheminformatics
  - Structure Search
  - SMILES
  humanURL: https://www.sigmaaldrich.com/US/en/support/contact-us
  properties:
  - url: https://www.sigmaaldrich.com/US/en/support/contact-us
    type: Documentation
  description: The Sigma-Aldrich Chemical Structure Search API enables substructure, exact structure, and similarity searches
    against the Sigma-Aldrich chemical catalog using SMILES, InChI, or molecular formula notation. Supports configuring similarity
    thresholds and returning ranked results for drug discovery, materials research, and synthetic chemistry workflows.
- aid: sigma-aldrich:sigma-aldrich-sds-api
  name: Sigma-Aldrich Safety Data Sheet API
  tags:
  - Safety
  - Safety Data Sheets
  - GHS
  - Compliance
  tags_raw:
  - Safety
  - SDS
  - GHS
  - Compliance
  humanURL: https://www.sigmaaldrich.com/US/en/support/sds-portal
  properties:
  - url: https://www.sigmaaldrich.com/US/en/support/sds-portal
    type: Documentation
  description: The Safety Data Sheet (SDS) API provides programmatic access to GHS- compliant Safety Data Sheets for all Sigma-Aldrich
    chemical products. Enables EHS systems, LIMS platforms, and safety management software to retrieve current SDSs in multiple
    languages and formats for regulatory compliance and laboratory safety management.
- aid: sigma-aldrich:sigma-aldrich-pricing-and-availability-api
  name: Sigma-Aldrich Pricing and Availability API
  description: Real-time pricing and global stock availability for Sigma-Aldrich products.
  humanURL: https://www.sigmaaldrich.com/US/en/technical-documents/technical-article/chemistry/labware/sigma-aldrich-developer-portal
  tags:
  - Pricing & Availability
  tags_raw:
  - Pricing and Availability
  properties:
  - type: OpenAPI
    url: openapi/sigma-aldrich-pricing-and-availability-api-openapi.yml
  - type: Documentation
    url: https://www.sigmaaldrich.com/US/en/technical-documents/technical-article/chemistry/labware/sigma-aldrich-developer-portal
  - type: SpectralRules
    url: rules/sigma-aldrich-rules.yml
  - type: JSONSchema
    url: json-schema/sigma-aldrich-product-schema.json
  - type: JSONLD
    url: json-ld/sigma-aldrich-context.jsonld
  - type: Vocabulary
    url: vocabulary/sigma-aldrich-vocabulary.yml
- aid: sigma-aldrich:sigma-aldrich-products-api
  name: Sigma-Aldrich Products API
  description: Product catalog search and retrieval for research chemicals, biochemicals, and laboratory supplies.
  humanURL: https://www.sigmaaldrich.com/US/en/technical-documents/technical-article/chemistry/labware/sigma-aldrich-developer-portal
  tags:
  - Product
  tags_raw:
  - Products
  properties:
  - type: OpenAPI
    url: openapi/sigma-aldrich-products-api-openapi.yml
  - type: Documentation
    url: https://www.sigmaaldrich.com/US/en/technical-documents/technical-article/chemistry/labware/sigma-aldrich-developer-portal
  - type: SpectralRules
    url: rules/sigma-aldrich-rules.yml
  - type: JSONSchema
    url: json-schema/sigma-aldrich-product-schema.json
  - type: JSONLD
    url: json-ld/sigma-aldrich-context.jsonld
  - type: Vocabulary
    url: vocabulary/sigma-aldrich-vocabulary.yml
- aid: sigma-aldrich:sigma-aldrich-safety-data-sheets-api
  name: Sigma-Aldrich Safety Data Sheets API
  description: Retrieval of GHS-compliant Safety Data Sheets for regulatory compliance and laboratory safety management.
  humanURL: https://www.sigmaaldrich.com/US/en/technical-documents/technical-article/chemistry/labware/sigma-aldrich-developer-portal
  tags:
  - Safety Data Sheets
  properties:
  - type: OpenAPI
    url: openapi/sigma-aldrich-safety-data-sheets-api-openapi.yml
  - type: Documentation
    url: https://www.sigmaaldrich.com/US/en/technical-documents/technical-article/chemistry/labware/sigma-aldrich-developer-portal
  - type: SpectralRules
    url: rules/sigma-aldrich-rules.yml
  - type: JSONSchema
    url: json-schema/sigma-aldrich-product-schema.json
  - type: JSONLD
    url: json-ld/sigma-aldrich-context.jsonld
  - type: Vocabulary
    url: vocabulary/sigma-aldrich-vocabulary.yml
- aid: sigma-aldrich:sigma-aldrich-structures-api
  name: Sigma-Aldrich Structures API
  description: Chemical structure search using SMILES, InChI, or molecular formula notation for cheminformatics workflows.
  humanURL: https://www.sigmaaldrich.com/US/en/technical-documents/technical-article/chemistry/labware/sigma-aldrich-developer-portal
  tags:
  - Structures
  properties:
  - type: OpenAPI
    url: openapi/sigma-aldrich-structures-api-openapi.yml
  - type: Documentation
    url: https://www.sigmaaldrich.com/US/en/technical-documents/technical-article/chemistry/labware/sigma-aldrich-developer-portal
  - type: SpectralRules
    url: rules/sigma-aldrich-rules.yml
  - type: JSONSchema
    url: json-schema/sigma-aldrich-product-schema.json
  - type: JSONLD
    url: json-ld/sigma-aldrich-context.jsonld
  - type: Vocabulary
    url: vocabulary/sigma-aldrich-vocabulary.yml
name: Sigma-Aldrich
tags:
- Life Sciences
- Chemistry
- Biochemistry
- Laboratory
- Research
- Chemical Catalog
tags_raw:
- Life Science
- Chemistry
- Biochemistry
- Laboratory
- Research
- Chemical Catalog
kind: contract
deliveryModel:
  model: unknown
  open_source: false
  commercial: false
  callable_host: true
  label: Delivery model not determined — needs a product licence on record
  confidence: low
  source:
  - openapi
  generated: '2026-08-28'
  method: derived
accessModel:
  pricing: enterprise
  onboarding: unknown
  trial: false
  try_now: false
  public: false
  label: Enterprise
  confidence: medium
  source:
  - plans
  - authentication
  - security
  generated: '2026-11-06'
  method: derived
image: https://kinlane-images.s3.amazonaws.com/shared/apis-json/icons/sigma-aldrich.png
access: 3rd-Party
created: '2025-01-01'
modified: '2026-05-19'
position: Consuming
segments:
- Life Science
- Chemistry
- Research Tools
description: Sigma-Aldrich was a leading life science and high technology company whose biochemical and organic chemical products,
  kits, and services are used in scientific research, including genomics, proteomics, and drug discovery. Acquired by Merck
  KGaA in 2015, Sigma-Aldrich now operates as part of MilliporeSigma in North America and Merck in other regions, continuing
  to provide the world's largest catalog of research chemicals, biochemicals, laboratory equipment, and life science products
  to researchers globally.
common:
- type: Plans
  url: plans/sigma-aldrich-plans-pricing.yml
- type: RateLimits
  url: rate-limits/sigma-aldrich-rate-limits.yml
- type: FinOps
  url: finops/sigma-aldrich-finops.yml
- type: AgenticAccess
  url: agentic-access/sigma-aldrich-agentic-access.yml
- type: DomainSecurity
  url: security/sigma-aldrich-domain-security.yml
- type: Authentication
  url: authentication/sigma-aldrich-authentication.yml
- type: LinkedIn
  url: https://www.linkedin.com/company/sigma-aldrich
- type: Website
  url: https://www.sigmaaldrich.com/
- type: ProductCatalog
  url: https://www.sigmaaldrich.com/US/en/catalog
- type: SDS Portal
  url: https://www.sigmaaldrich.com/US/en/support/sds-portal
- type: DeveloperPortal
  url: https://www.sigmaaldrich.com/US/en/technical-documents/technical-article/chemistry/labware/sigma-aldrich-developer-portal
- type: Parent Company
  url: https://www.merckgroup.com/
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
specificationVersion: '0.23'

Sigma-Aldrich API — frequently asked questions

Does Sigma-Aldrich have an API?

Yes. APIs.io lists 6 APIs from Sigma-Aldrich, including Sigma-Aldrich Chemical Structure Search API, Sigma-Aldrich Safety Data Sheet API and Sigma-Aldrich Pricing and Availability API, and 3 more.

Is there an OpenAPI specification for the Sigma-Aldrich API?

Yes. APIs.io indexes 4 OpenAPI specifications for Sigma-Aldrich, each linked for download from this page.

How do I authenticate with the Sigma-Aldrich API?

Sigma-Aldrich uses bearer-token authentication (apiKey · 1 scheme). The details are profiled on APIs.io as Sigma Aldrich Authentication.

How much does the Sigma-Aldrich API cost?

APIs.io lists 1 pricing plan for Sigma-Aldrich, with each plan's price, limits and inclusions under Pricing on this page.

Is the Sigma-Aldrich API ready for AI agents?

Sigma-Aldrich has a Kin Score of 32.2 out of 100 (thin) and an Agent Readiness score of 20.7 (agent-aware), scored by API Evangelist on 2026-11-06.

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