Seaport Therapeutics

Seaport Therapeutics is a Boston-based clinical-stage biopharmaceutical company developing new medicines for patients with depression, anxiety and other neuropsychiatric disorders. Its proprietary Glyph platform — licensed from the Porter Research Group at Monash University — applies lymphatic-targeting oral prodrug chemistry so that more medicine reaches the bloodstream and brain while bypassing first-pass liver metabolism and reducing side effects. The clinical pipeline includes GlyphAllo (SPT-300), an oral allopregnanolone prodrug in Phase 2 for major depressive disorder; GlyphAgo (SPT-320), an oral agomelatine prodrug in Phase 2 for generalized anxiety disorder; and Glyph2BLSD (SPT-348), a pre-clinical non-hallucinogenic 2-bromo-LSD neuroplastogen. Seaport publishes no public API, developer portal, SDK or machine-readable specification; its public web surface is a corporate WordPress site plus a hosted investor-relations subdomain.

Seaport Therapeutics is profiled on the APIs.io network. Tagged areas include Company, Biotechnology, Pharmaceuticals, Life Sciences, and Clinical Trials.

🌐 Visit website 📡 Profile data on GitHub

8.9/100 minimal ▬ flat Agent 0/100 human only Front door AI 1/6 silent Heartbeat 100/100 alive saas Full breakdown ↓
scored 2026-11-06 · rubric v0.27.0 · Show this score on your site →

0 APIs

Company Biotechnology Pharmaceuticals Life Sciences Clinical Trials Neuroscience Drug Delivery

Kin Score

Kin Score How this is scored →
scored 2026-11-06 · rubric v0.27.0

Composite quality — 8.9/100 · minimal

Contract Quality 0.0 / 21

Developer Ergonomics 0.0 / 17

Access Clarity 3.6 / 17

Operational Transparency 0.0 / 11

Contract Governance 0.0 / 10

Discoverability 4.1 / 9

Regulatory Posture 1.6 / 15

Agent readiness — 0/100 · human only

Machine-Readable Contract 0 / 18

Agentic Access Contract 0 / 10

Documented Reversibility 0 / 6

MCP Server 0 / 12

Machine-Readable Auth 0 / 10

Idempotency 0 / 9

Stable Error Semantics 0 / 8

Request/Response Examples 0 / 7

Rate-Limit Signaling 0 / 7

Typed Event Surface 0 / 6

Agent Skills 0 / 5

Well-Known Catalog 0 / 4

Consent & Bot Identity 0 / 3

A2A Agent Card 0 / 8

Dry-Run / Simulate Mode 0 / 4

Delegated User Identity 0 / 6

Protected Resource Metadata 0 / 5

Registration Without a Human 0 / 6

Agentic Commerce Well-Known Document 0 / 5

Pagination 5 / 5

Distinct Operations 3 / 3

MCP Tool Quality 6 / 6

Regulatory Posture applies to this provider. Its tags matched the Health regime, so Regulatory Posture carries 15 points of the composite. If this regime is wrong for your business, say so on your provider repo — the applicability map is public and we will correct it.

Create-or-Update Ergonomics could not be measured. We hold no machine-readable contract for this provider to read, so there is nothing to measure a write surface against. Excluded rather than scored zero: never-measured and measured-empty are different facts. Publishing an OpenAPI is what makes this facet — and several others — scorable at all.

The six quality facets above are damped to 85 points between them, because the conditional facet above carries the other 15. That is why each facet's contribution is shown against a damped maximum: raising a quality facet moves the composite by 85% of its nominal weight, not 100%. The full arithmetic is at apis.io/rating/.

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Agent readiness — checks not met, largest first (exact, from this profile):

Machine-Readable Contract +18 pts — api_specs includes an OpenAPI document
MCP Server +12 pts — deployment.mode + probe verdict on the mcp/ manifest, not the pointer; an unprobed slug falls back to authorship
Agentic Access Contract +10 pts — agentic_access artifact present (x-agentic-access), graded by author
Machine-Readable Auth +10 pts — a served openid-configuration/oauth-authorization-server carrying `issuer` (served), else the securitySchemes class in the provider OpenAPIs — bound (mutualTLS, DPoP, Signature) > negotiable (oauth2 authorizationCode/clientCredentials, openIdConnect) > bearer (http bearer, apiKey)
Idempotency +9 pts — OpenAPI mutating operations declare an idempotency key — a header, a request-body property, or a named de-duplication token whose own description says so (verified); else common[].type matches /idempoten/i (documented)
Stable Error Semantics +8 pts — OpenAPI $refs a shared error schema across 4xx/5xx responses (verified), else common[].type includes ErrorCatalog / ErrorCodes / DeclineCodes

13 more unmet checks in the Agent Readiness table above.

Kin Score — facets with the most composite points still available (weight × headroom):

Contract Quality scores 0.0 — up to +25.0 composite points
Developer Ergonomics scores 0.0 — up to +20.0 composite points
Access Clarity scores 21.1 — up to +15.8 composite points

Each check links to what satisfies it. Publish the artifact, or tell us where it already lives, and the score moves on the next scoring run.

Improve this rating by publishing the missing artifacts — every area above can be raised, and the full rubric is at apis.io/rating/. Every facet and dimension name above is a link: it opens that measurement's own page — what it means, the exact checks that feed it, how the whole catalog distributes on it, and the providers at the top of it. This rating is computed from the provider profile at artifacts.apis.io/seaport-therapeutics/apis.yml: open an issue on github.com/api-evangelist/seaport-therapeutics to ask a question or point us at an artifact you publish. Submit an artifact on GitHub — free → Manage your own listing — the Influence plan, $499/mo →

Security Posture 1

Authentication, domain security, vulnerability disclosure, and trust-center signals.

Seaport Therapeutics Domain Security

TLSv1.3 · DMARC

SECURITY

Resources

Access & Security 1

Authentication, authorization, and security posture

DomainSecurity

DomainSecurity

Commercial 2

Pricing, plans, and the legal terms of use

PrivacyPolicy

PrivacyPolicy

TermsOfService

TermsOfService

Company 2

The organization behind the API

BlogRSS

BlogRSS

Website

Website

Source (apis.yml)

aid: seaport-therapeutics
name: Seaport Therapeutics
description: Seaport Therapeutics is a Boston-based clinical-stage biopharmaceutical company developing new medicines for
  patients with depression, anxiety and other neuropsychiatric disorders. Its proprietary Glyph platform — licensed from the
  Porter Research Group at Monash University — applies lymphatic-targeting oral prodrug chemistry so that more medicine reaches
  the bloodstream and brain while bypassing first-pass liver metabolism and reducing side effects. The clinical pipeline includes
  GlyphAllo (SPT-300), an oral allopregnanolone prodrug in Phase 2 for major depressive disorder; GlyphAgo (SPT-320), an oral
  agomelatine prodrug in Phase 2 for generalized anxiety disorder; and Glyph2BLSD (SPT-348), a pre-clinical non-hallucinogenic
  2-bromo-LSD neuroplastogen. Seaport publishes no public API, developer portal, SDK or machine-readable specification; its
  public web surface is a corporate WordPress site plus a hosted investor-relations subdomain.
url: https://raw.githubusercontent.com/api-evangelist/seaport-therapeutics/refs/heads/main/apis.yml
deliveryModel:
  model: saas
  open_source: false
  commercial: true
  callable_host: false
  label: Hosted service · you call their endpoint
  confidence: medium
  source:
  - pricing
  generated: '2026-08-28'
  method: derived
accessModel:
  pricing: unknown
  onboarding: unknown
  trial: false
  try_now: false
  public: false
  label: Unknown
  confidence: low
  probe_state: none
  source:
  - security
  generated: '2026-11-06'
  method: derived
image: https://seaporttx.com/wp-content/uploads/2023/11/seaport_logo.png
x-type: company
x-source: harvest:secondary-market
specificationVersion: '0.20'
created: '2026-08-26'
modified: '2026-10-06'
tags:
- Company
- Biotechnology
- Pharmaceuticals
- Life Sciences
- Clinical Trials
- Neuroscience
- Drug Delivery
apis: []
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- url: https://seaporttx.com/feed/
  type: BlogRSS
- type: DomainSecurity
  url: security/seaport-therapeutics-domain-security.yml
- type: Website
  url: https://seaporttx.com/
- type: PrivacyPolicy
  url: https://seaporttx.com/privacy-policy/
- type: TermsOfService
  url: https://seaporttx.com/terms-of-use/
x-enrichment:
  date: '2026-08-26'
  status: minimal
  artifacts_added: 2
  pass: local-v1
x-coverage:
  state: none
  reason: not-a-software-company
  detail: Seaport Therapeutics is a clinical-stage neuropsychiatric drug developer whose product is the Glyph oral-prodrug
    platform, not software; seaporttx.com is a corporate WordPress site that returns a real 404 on every OpenAPI, GraphQL,
    llms.txt and /.well-known/ path, and its only machine-readable document is the WordPress core /wp-json/ discovery index
    that ships with the CMS.
  evidence:
  - url: https://seaporttx.com/openapi.json
    status: 404
  - url: https://seaporttx.com/llms.txt
    status: 404
  - url: https://seaporttx.com/.well-known/agent-card.json
    status: 404
  - url: https://seaporttx.com/wp-json/
    status: 200
  - url: https://investors.seaporttx.com/
    status: 0
  checked: '2026-08-26'

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