Pearl is a dental AI computer-vision company whose FDA-cleared products - Second Opinion (real-time pathology and restorative detection on 2D and 3D dental radiographs), Practice Intelligence (clinical and operational analytics over full practice-management-system data), and Precheck (AI insurance claim review) - are delivered by embedding Pearl's cloud AI into third-party imaging and practice management software rather than through a public, self-serve developer API. Pearl integrates natively with 40+ imaging/PMS platforms (DEXIS, Carestream, Planmeca Romexis, Dentsply Sirona Sidexis, Apteryx XVWeb, MiPACS, Open Dental, Dentrix, Eaglesoft, Curve, Denticon, Software of Excellence EXACT) and is an authorized vendor in the Henry Schein One API Exchange. There is no publicly documented, self-signup Pearl developer API, SDK, or OpenAPI reference; API access is partner/OEM-gated and arranged through Pearl's integrations and sales teams. The API surfaces below are modeled from Pearl's public product descriptions and integration architecture, not from published Pearl API reference documentation.
Partner/OEM-gated cloud AI surface behind Second Opinion. When an imaging partner uploads a bitewing, periapical, panoramic, or CBCT radiograph, Pearl's cloud computer-vision se...
Practice Intelligence pairs Pearl's diagnostic AI with full practice-management-system data to surface clinical quality, financial performance, appointment compliance, case acce...
The integration/enablement layer through which Pearl is provisioned inside third-party imaging and practice management systems - including as an authorized vendor in the Henry S...
aid: pearl-dental
url: https://raw.githubusercontent.com/api-evangelist/pearl-dental/refs/heads/main/apis.yml
name: Pearl
kind: company
description: Pearl is a dental AI computer-vision company whose FDA-cleared products - Second Opinion (real-time pathology
and restorative detection on 2D and 3D dental radiographs), Practice Intelligence (clinical and operational analytics over
full practice-management-system data), and Precheck (AI insurance claim review) - are delivered by embedding Pearl's cloud
AI into third-party imaging and practice management software rather than through a public, self-serve developer API. Pearl
integrates natively with 40+ imaging/PMS platforms (DEXIS, Carestream, Planmeca Romexis, Dentsply Sirona Sidexis, Apteryx
XVWeb, MiPACS, Open Dental, Dentrix, Eaglesoft, Curve, Denticon, Software of Excellence EXACT) and is an authorized vendor
in the Henry Schein One API Exchange. There is no publicly documented, self-signup Pearl developer API, SDK, or OpenAPI
reference; API access is partner/OEM-gated and arranged through Pearl's integrations and sales teams. The API surfaces below
are modeled from Pearl's public product descriptions and integration architecture, not from published Pearl API reference
documentation.
image: https://kinlane-images.s3.amazonaws.com/shared/apis-json/apis-json-logo.jpg
tags:
- AI
- Dental
- Computer Vision
- Radiology
- Medical Imaging
- Pathology Detection
- Healthcare
- Partner Gated
created: '2026-07-05'
modified: '2026-07-05'
specificationVersion: '0.19'
apis:
- aid: pearl-dental:pearl-dental-second-opinion-image-analysis-api
name: Pearl Second Opinion Image Analysis API
tags:
- Image Analysis
- Radiographs
- Pathology Detection
- Partner Gated
- Modeled
image: https://kinlane-images.s3.amazonaws.com/shared/apis-json/apis-json-logo.jpg
humanURL: https://hellopearl.com/products/second-opinion
properties:
- url: https://hellopearl.com/products/second-opinion
type: Documentation
- url: https://www.hellopearl.com/native-integration
type: Integrations
description: Partner/OEM-gated cloud AI surface behind Second Opinion. When an imaging partner uploads a bitewing, periapical,
panoramic, or CBCT radiograph, Pearl's cloud computer-vision service analyzes it and returns detections - up to 18 findings
per image (incipient/progressed caries, bone loss with millimeter and ratio measurements, calculus, periapical radiolucencies,
defective margins, widened PDL, impactions) plus existing restorations (crowns, fillings, bridges, root canals, implants)
- as labeled bounding boxes and metadata overlaid on the original image. There is no public, self-serve developer reference
for this surface; endpoints are modeled from Pearl's product and integration descriptions.
- aid: pearl-dental:pearl-dental-practice-intelligence-analytics-api
name: Pearl Practice Intelligence Analytics API
tags:
- Analytics
- Practice Management
- Clinical Performance
- Partner Gated
- Modeled
image: https://kinlane-images.s3.amazonaws.com/shared/apis-json/apis-json-logo.jpg
humanURL: https://hellopearl.com/products/practice-intelligence
properties:
- url: https://hellopearl.com/products/practice-intelligence
type: Documentation
- url: https://www.hellopearl.com/native-integration
type: Integrations
description: Practice Intelligence pairs Pearl's diagnostic AI with full practice-management-system data to surface clinical
quality, financial performance, appointment compliance, case acceptance, and per-provider production across one location
or hundreds. It integrates by consuming a PMS that "exposes a public API or accessible data layer" (Open Dental, Dentrix,
Eaglesoft, Carestack, Oryx, Curve, Denticon, EXACT), with custom integrations delivered in ~40 business days. Pearl does
not publish a self-serve developer API for the resulting analytics; this surface is modeled from public product documentation.
- aid: pearl-dental:pearl-dental-pms-integration-exchange-api
name: Pearl PMS Integration Exchange API
tags:
- Integrations
- Practice Management
- API Exchange
- Partner Gated
- Modeled
image: https://kinlane-images.s3.amazonaws.com/shared/apis-json/apis-json-logo.jpg
humanURL: https://www.hellopearl.com/press-release/pearl-joins-henry-schein-one-api-exchange-as-an-authorized-integration-vendor
properties:
- url: https://www.hellopearl.com/native-integration
type: Documentation
- url: https://management.hellopearl.com/
type: Portal
description: The integration/enablement layer through which Pearl is provisioned inside third-party imaging and practice
management systems - including as an authorized vendor in the Henry Schein One API Exchange for Dentrix and Dentrix Ascend.
Practices and DSOs are onboarded (remote install, historical data ingestion, phased go-live, up to 50 offices per month)
and managed via the Pearl Management Portal. This is a partner/vendor-facing integration process, not a public developer
API; endpoints are modeled and not published by Pearl.
common:
- type: DomainSecurity
url: security/pearl-dental-domain-security.yml
- type: LinkedIn
url: https://www.linkedin.com/company/hellopearl
- type: Website
url: https://hellopearl.com
- type: Documentation
url: https://help.hellopearl.com
- type: Integrations
url: https://www.hellopearl.com/native-integration
- type: Portal
url: https://management.hellopearl.com/
- type: Plans
url: plans/pearl-dental-plans-pricing.yml
- type: Blog
url: https://hellopearl.com/blog
maintainers:
- FN: Kin Lane
email: kin@apievangelist.com