Pearl

Pearl is a dental AI computer-vision company whose FDA-cleared products - Second Opinion (real-time pathology and restorative detection on 2D and 3D dental radiographs), Practice Intelligence (clinical and operational analytics over full practice-management-system data), and Precheck (AI insurance claim review) - are delivered by embedding Pearl's cloud AI into third-party imaging and practice management software rather than through a public, self-serve developer API. Pearl integrates natively with 40+ imaging/PMS platforms (DEXIS, Carestream, Planmeca Romexis, Dentsply Sirona Sidexis, Apteryx XVWeb, MiPACS, Open Dental, Dentrix, Eaglesoft, Curve, Denticon, Software of Excellence EXACT) and is an authorized vendor in the Henry Schein One API Exchange. There is no publicly documented, self-signup Pearl developer API, SDK, or OpenAPI reference; API access is partner/OEM-gated and arranged through Pearl's integrations and sales teams. The API surfaces below are modeled from Pearl's public product descriptions and integration architecture, not from published Pearl API reference documentation.

3 APIs 0 Features
AIDentalComputer VisionRadiologyMedical ImagingPathology DetectionHealthcarePartner Gated

APIs

Pearl Second Opinion Image Analysis API

Partner/OEM-gated cloud AI surface behind Second Opinion. When an imaging partner uploads a bitewing, periapical, panoramic, or CBCT radiograph, Pearl's cloud computer-vision se...

Pearl Practice Intelligence Analytics API

Practice Intelligence pairs Pearl's diagnostic AI with full practice-management-system data to surface clinical quality, financial performance, appointment compliance, case acce...

Pearl PMS Integration Exchange API

The integration/enablement layer through which Pearl is provisioned inside third-party imaging and practice management systems - including as an authorized vendor in the Henry S...

Pricing Plans

Resources

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DomainSecurity
DomainSecurity
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LinkedIn
LinkedIn
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Website
Website
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Documentation
Documentation
🌐
Portal
Portal
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Plans
Plans
📰
Blog
Blog

Sources

apis.yml Raw ↑
aid: pearl-dental
url: https://raw.githubusercontent.com/api-evangelist/pearl-dental/refs/heads/main/apis.yml
name: Pearl
kind: company
description: Pearl is a dental AI computer-vision company whose FDA-cleared products - Second Opinion (real-time pathology
  and restorative detection on 2D and 3D dental radiographs), Practice Intelligence (clinical and operational analytics over
  full practice-management-system data), and Precheck (AI insurance claim review) - are delivered by embedding Pearl's cloud
  AI into third-party imaging and practice management software rather than through a public, self-serve developer API. Pearl
  integrates natively with 40+ imaging/PMS platforms (DEXIS, Carestream, Planmeca Romexis, Dentsply Sirona Sidexis, Apteryx
  XVWeb, MiPACS, Open Dental, Dentrix, Eaglesoft, Curve, Denticon, Software of Excellence EXACT) and is an authorized vendor
  in the Henry Schein One API Exchange. There is no publicly documented, self-signup Pearl developer API, SDK, or OpenAPI
  reference; API access is partner/OEM-gated and arranged through Pearl's integrations and sales teams. The API surfaces below
  are modeled from Pearl's public product descriptions and integration architecture, not from published Pearl API reference
  documentation.
image: https://kinlane-images.s3.amazonaws.com/shared/apis-json/apis-json-logo.jpg
tags:
- AI
- Dental
- Computer Vision
- Radiology
- Medical Imaging
- Pathology Detection
- Healthcare
- Partner Gated
created: '2026-07-05'
modified: '2026-07-05'
specificationVersion: '0.19'
apis:
- aid: pearl-dental:pearl-dental-second-opinion-image-analysis-api
  name: Pearl Second Opinion Image Analysis API
  tags:
  - Image Analysis
  - Radiographs
  - Pathology Detection
  - Partner Gated
  - Modeled
  image: https://kinlane-images.s3.amazonaws.com/shared/apis-json/apis-json-logo.jpg
  humanURL: https://hellopearl.com/products/second-opinion
  properties:
  - url: https://hellopearl.com/products/second-opinion
    type: Documentation
  - url: https://www.hellopearl.com/native-integration
    type: Integrations
  description: Partner/OEM-gated cloud AI surface behind Second Opinion. When an imaging partner uploads a bitewing, periapical,
    panoramic, or CBCT radiograph, Pearl's cloud computer-vision service analyzes it and returns detections - up to 18 findings
    per image (incipient/progressed caries, bone loss with millimeter and ratio measurements, calculus, periapical radiolucencies,
    defective margins, widened PDL, impactions) plus existing restorations (crowns, fillings, bridges, root canals, implants)
    - as labeled bounding boxes and metadata overlaid on the original image. There is no public, self-serve developer reference
    for this surface; endpoints are modeled from Pearl's product and integration descriptions.
- aid: pearl-dental:pearl-dental-practice-intelligence-analytics-api
  name: Pearl Practice Intelligence Analytics API
  tags:
  - Analytics
  - Practice Management
  - Clinical Performance
  - Partner Gated
  - Modeled
  image: https://kinlane-images.s3.amazonaws.com/shared/apis-json/apis-json-logo.jpg
  humanURL: https://hellopearl.com/products/practice-intelligence
  properties:
  - url: https://hellopearl.com/products/practice-intelligence
    type: Documentation
  - url: https://www.hellopearl.com/native-integration
    type: Integrations
  description: Practice Intelligence pairs Pearl's diagnostic AI with full practice-management-system data to surface clinical
    quality, financial performance, appointment compliance, case acceptance, and per-provider production across one location
    or hundreds. It integrates by consuming a PMS that "exposes a public API or accessible data layer" (Open Dental, Dentrix,
    Eaglesoft, Carestack, Oryx, Curve, Denticon, EXACT), with custom integrations delivered in ~40 business days. Pearl does
    not publish a self-serve developer API for the resulting analytics; this surface is modeled from public product documentation.
- aid: pearl-dental:pearl-dental-pms-integration-exchange-api
  name: Pearl PMS Integration Exchange API
  tags:
  - Integrations
  - Practice Management
  - API Exchange
  - Partner Gated
  - Modeled
  image: https://kinlane-images.s3.amazonaws.com/shared/apis-json/apis-json-logo.jpg
  humanURL: https://www.hellopearl.com/press-release/pearl-joins-henry-schein-one-api-exchange-as-an-authorized-integration-vendor
  properties:
  - url: https://www.hellopearl.com/native-integration
    type: Documentation
  - url: https://management.hellopearl.com/
    type: Portal
  description: The integration/enablement layer through which Pearl is provisioned inside third-party imaging and practice
    management systems - including as an authorized vendor in the Henry Schein One API Exchange for Dentrix and Dentrix Ascend.
    Practices and DSOs are onboarded (remote install, historical data ingestion, phased go-live, up to 50 offices per month)
    and managed via the Pearl Management Portal. This is a partner/vendor-facing integration process, not a public developer
    API; endpoints are modeled and not published by Pearl.
common:
- type: DomainSecurity
  url: security/pearl-dental-domain-security.yml
- type: LinkedIn
  url: https://www.linkedin.com/company/hellopearl
- type: Website
  url: https://hellopearl.com
- type: Documentation
  url: https://help.hellopearl.com
- type: Integrations
  url: https://www.hellopearl.com/native-integration
- type: Portal
  url: https://management.hellopearl.com/
- type: Plans
  url: plans/pearl-dental-plans-pricing.yml
- type: Blog
  url: https://hellopearl.com/blog
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com