Parasma

Parasma is a San Francisco based biological compute startup building algorithms and hardware that train living human brain cells (cortical neurons on a chip) to perform computation for AI workloads. Founded in 2026 by Sean Cole and backed by Y Combinator (Summer 2026 batch), the company grew out of research that taught a clump of lab-grown human neurons to play Doom, coverage of which appeared in Nature, The Economist, Scientific American, The Guardian and elsewhere. Parasma currently operates as an early-stage research company with a marketing and news website; it does not yet publish a public API, SDK, developer portal, or other machine-readable developer surface. This profile is tracked in the API Evangelist network as a company lead so any future developer platform can be captured when it ships.

Parasma is profiled on the APIs.io network. Tagged areas include Company, Biological Compute, Neurotechnology, Artificial Intelligence, and Machine-Learning.

Parasma’s developer surface includes engineering blog, YouTube channel, and 7 more developer resources.

🌐 Visit website 📡 Source on GitHub

5.5/100 minimal ▬ flat Agent 0/100 human only Full breakdown ↓
scored 2026-09-08 · rubric v0.20.0

0 APIs

CompanyBiological ComputeNeurotechnology Artificial Intelligence Machine-LearningWetwareCompute Research Y Combinator

Kin Score

Kin Score How this is scored →
scored 2026-09-08 · rubric v0.20.0

Composite quality — 5.5/100 · minimal

Contract Quality 0.0 / 25

Developer Ergonomics 0.5 / 20

Access Clarity 0.0 / 20

Operational Transparency 0.0 / 13

Contract Governance 0.0 / 12

Discoverability 5.0 / 10

Agent readiness — 0/100 · human only

Machine-Readable Contract 0 / 18

Agentic Access Contract 0 / 10

Documented Reversibility 0 / 6

MCP Server 0 / 12

Machine-Readable Auth 0 / 10

Idempotency 0 / 9

Stable Error Semantics 0 / 8

Request/Response Examples 0 / 7

Rate-Limit Signaling 0 / 7

Typed Event Surface 0 / 6

Agent Skills 0 / 5

Well-Known Catalog 0 / 4

Consent & Bot Identity 0 / 3

A2A Agent Card 0 / 8

Dry-Run / Simulate Mode 0 / 4

Delegated User Identity 0 / 6

Protected Resource Metadata 0 / 5

Registration Without a Human 0 / 6

Agentic Commerce Well-Known Document 0 / 5

Create-or-Update Ergonomics could not be measured. We hold no machine-readable contract for this provider to read, so there is nothing to measure a write surface against. Excluded rather than scored zero: never-measured and measured-empty are different facts. Publishing an OpenAPI is what makes this facet — and several others — scorable at all.

Improve this rating by publishing the missing artifacts — every area above can be raised, and the full rubric is at apis.io/rating/. Every facet and dimension name above is a link: it opens that measurement's own page — what it means, the exact checks that feed it, how the whole catalog distributes on it, and the providers at the top of it. This rating is computed from github.com/api-evangelist/parasma: open an issue to ask a question, or submit a pull request to add artifacts. Submit an artifact on GitHub — free → Manage your own listing — the Influence plan, $499/mo →

Security Posture 1

Authentication, domain security, vulnerability disclosure, and trust-center signals.

Parasma Domain Security

TLSv1.3

SECURITY

Resources

Access & Security 1

Authentication, authorization, and security posture

DomainSecurity

DomainSecurity

Learn 1

Tutorials, courses, talks, and written guidance

YouTube

YouTube

Company 5

The organization behind the API

Website

Website

About

About

Blog

Blog

LinkedIn

Twitter

Twitter

Other 2

Properties that don't map to a standard resource type

Research

Research

Source (apis.yml)

aid: parasma
name: Parasma
description: Parasma is a San Francisco based biological compute startup building algorithms and hardware that train living
  human brain cells (cortical neurons on a chip) to perform computation for AI workloads. Founded in 2026 by Sean Cole and
  backed by Y Combinator (Summer 2026 batch), the company grew out of research that taught a clump of lab-grown human neurons
  to play Doom, coverage of which appeared in Nature, The Economist, Scientific American, The Guardian and elsewhere. Parasma
  currently operates as an early-stage research company with a marketing and news website; it does not yet publish a public
  API, SDK, developer portal, or other machine-readable developer surface. This profile is tracked in the API Evangelist network
  as a company lead so any future developer platform can be captured when it ships.
url: https://raw.githubusercontent.com/api-evangelist/parasma/refs/heads/main/apis.yml
deliveryModel:
  model: unknown
  open_source: false
  commercial: false
  callable_host: false
  label: Delivery model not determined — needs a product licence on record
  confidence: low
  source:
  - none
  generated: '2026-08-28'
  method: derived
accessModel:
  pricing: unknown
  onboarding: unknown
  trial: false
  try_now: false
  public: false
  label: Unknown
  confidence: low
  source: []
  generated: '2026-07-22'
  method: derived
image: https://parasma.com/wordmark_black_on_white.png
x-type: company
x-source: vc-portfolio
x-backed-by:
- y-combinator
x-tier: stub
x-tier-reason: portfolio-lead
x-stage: pre-api
specificationVersion: '0.23'
created: '2026-07-17'
modified: '2026-07-20'
tags:
- Company
- Biological Compute
- Neurotechnology
- Artificial Intelligence
- Machine-Learning
- Wetware
- Compute
- Research
- Y Combinator
tags_raw:
- Company
- Biological Compute
- Neurotechnology
- Artificial Intelligence
- Machine Learning
- Wetware
- Compute
- Research
- Y Combinator
apis: []
common:
- type: DomainSecurity
  url: security/parasma-domain-security.yml
- type: Website
  url: https://parasma.com/
- type: About
  url: https://parasma.com/about
- type: Blog
  url: https://parasma.com/news
- type: Research
  url: https://parasma.com/research
- type: LinkedIn
  url: https://www.linkedin.com/company/parasma/
- type: Twitter
  url: https://x.com/ParasmaAI
- type: YouTube
  url: https://www.youtube.com/@ParasmaAI
- type: X
  url: https://x.com/ParasmaAI
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
x-enrichment:
  date: '2026-07-20'
  status: minimal
  artifacts_added: 1
  pass: local-v1

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