Orionis Biosciences

aid: orionis-biosciences
name: Orionis Biosciences
description: Orionis Biosciences is a privately held biotechnology company headquartered at 950 Winter Street in Waltham,
  Massachusetts, with a research site in Ghent, Belgium, co-founded by Niko Kley and Jan Tavernier. It develops precision
  medicines across three modalities — small molecule molecular glues built on its Allo-Glue platform, conditional and cis-targeted
  cytokines built on its A-Kine platform, and multi-specific cell engagers built on its MCE platform — combining disease biology,
  immunology, chemistry, protein engineering, computational science and machine learning at genome scale. Its lead A-Kine
  program ORB-011, an attenuated cis-targeted interferon immunotherapy, has entered Phase 1. Orionis has run multi-year molecular-glue
  discovery collaborations with Genentech (2023, and a 2025 expansion with $105M upfront and more than $2B in potential milestones)
  and Novartis (from 2020, expanded in 2026 with $40M upfront and up to $1.4B in milestones). Orionis Biosciences publishes
  no developer program, no product API and no OpenAPI of its own; the only machine-readable surface on orionisbio.com is the
  WordPress REST API (wp/v2) that serves the company newsroom, corporate and platform pages, leadership and scientific-team
  profiles and the media library as anonymously readable JSON, alongside a WordPress Abilities API (wp-abilities/v1) registry
  that is present but authentication-gated.
url: https://raw.githubusercontent.com/api-evangelist/orionis-biosciences/refs/heads/main/apis.yml
x-type: company
x-source: harvest:secondary-market
x-tier: profiled
x-tier-reason: enrichment-pipeline
deliveryModel:
  model: saas
  open_source: false
  commercial: true
  callable_host: true
  label: Hosted service · you call their endpoint
  confidence: high
  source:
  - openapi
  - pricing
  generated: '2026-08-28'
  method: derived
accessModel:
  pricing: unknown
  onboarding: unknown
  trial: false
  try_now: false
  public: false
  label: Unknown
  confidence: low
  probe_state: covered
  source:
  - authentication
  - security
  generated: '2026-09-03'
  method: derived
image: https://orionisbio.com/wp-content/uploads/2020/02/cropped-favicon-coast-192x192.png
specificationVersion: '0.23'
created: '2026-08-04'
modified: '2026-08-04'
tags:
- Company
- Biotechnology
- Life Sciences
- Drug Discovery
- Pharmaceuticals
- Oncology
- Immunotherapy
- Protein Engineering
- Molecular Glues
- Computational Biology
- Machine Learning
- Clinical Trials
- Content
tags_raw:
- Company
- Biotechnology
- Life Sciences
- Drug Discovery
- Pharmaceuticals
- Oncology
- Immunotherapy
- Protein Engineering
- Molecular Glues
- Computational Biology
- Machine Learning
- Clinical Trials
- Content
- Machine-Learning
apis:
- aid: orionis-biosciences:orionisbio-com-website-wordpress-rest
  name: Orionis Biosciences Website (WordPress REST)
  description: 'The public WordPress REST API (wp-json) of the Orionis Biosciences website at orionisbio.com: the route index
    of the site''s content management system, catalogued as one site surface rather than as separate APIs.'
  baseURL: https://orionisbio.com/wp-json
  tags:
  - WordPress
  x-surface: platform-generated
  properties:
  - type: Documentation
    url: https://orionisbio.com/wp-json
  x-platform: wordpress
  x-platform-surface: rest
x-enrichment:
  date: '2026-08-04'
  status: enriched
  artifacts_added: 20
  pass: local-v1
x-coverage:
  state: covered
  reason: covered
  detail: Orionis Biosciences runs no developer program, but contract discovery found a real provider-served machine-readable
    surface — the WordPress REST route index at https://orionisbio.com/wp-json/ (HTTP 200), whose wp/v2 namespace returns
    the newsroom, platform pages, the orionis_team profiles and the media library anonymously. That index was saved verbatim
    and the OpenAPI, data model, error catalog, conventions and skills were derived from it.
  evidence:
  - url: https://orionisbio.com/wp-json/
    status: 200
  - url: https://orionisbio.com/wp-json/wp/v2/posts
    status: 200
  - url: https://orionisbio.com/.well-known/agent-card.json
    status: 404
  - url: https://orionisbio.com/llms.txt
    status: 404
  checked: '2026-08-04'
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: X-MCPServerCandidate
  url: mcp/orionis-biosciences-mcp.yml
  note: 'Renamed from MCPServer 2026-09-03 (roadmap#247): the manifest self-describes as status: candidate — a tool list derived
    from the published API contracts, not an existing server. The scorer already read the manifest and reported mcp_server
    correctly; the MCPServer type was crediting the artifact-type surfaces with a server that does not exist.'
- type: Overlay
  url: overlays/orionis-biosciences-content-overlay.yaml
- type: Website
  url: https://orionisbio.com/
- type: About
  url: https://orionisbio.com/about-us/
- type: Blog
  url: https://orionisbio.com/news/
- type: BlogRSS
  url: https://orionisbio.com/feed/
- type: News
  url: https://orionisbio.com/news/
- type: Support
  url: https://orionisbio.com/contact/
- type: Team
  url: https://orionisbio.com/about-us/executive-team/
- type: Technology
  url: https://orionisbio.com/platforms/
- type: Pipeline
  url: https://orionisbio.com/pipeline/
- type: TermsOfService
  url: https://orionisbio.com/terms-of-use/
- type: PrivacyPolicy
  url: https://orionisbio.com/privacy-policy/
- type: CookiePolicy
  url: https://orionisbio.com/cookie-policy/
- type: LinkedIn
  url: https://www.linkedin.com/company/orionis-biosciences/
- type: Twitter
  url: https://twitter.com/orionisbio
- type: SecondaryMarket
  url: https://forgeglobal.com/orionis-biosciences_stock/
- type: Packages
  url: packages/orionis-biosciences-packages.yml
- type: LLMsTxt
  url: llms/orionis-biosciences-llms.txt
- type: WellKnown
  url: well-known/orionis-biosciences-well-known.yml
- type: Authentication
  url: authentication/orionis-biosciences-authentication.yml
- type: Conventions
  url: conventions/orionis-biosciences-conventions.yml
- type: Conformance
  url: conformance/orionis-biosciences-conformance.yml
- type: Lifecycle
  url: lifecycle/orionis-biosciences-lifecycle.yml
- type: DomainSecurity
  url: security/orionis-biosciences-domain-security.yml
- type: AgenticAccess
  url: agentic-access/orionis-biosciences-agentic-access.yml
- type: AgentSkill
  url: skills/_index.yml
- type: DataModel
  url: data-model/orionis-biosciences-data-model.yml
- type: ErrorCatalog
  url: errors/orionis-biosciences-problem-types.yml