Opentrons

Opentrons is a lab automation platform providing a REST HTTP API and Python Protocol API for controlling liquid handling robots such as the Opentrons Flex and OT-2. Developers can programmatically manage protocols, control pipettes, run liquid handling workflows, manage labware, and integrate biology lab automation into their applications. The HTTP API operates on-robot over a local network and exposes OpenAPI-defined endpoints for protocol upload, run management, atomic liquid handling commands, and hardware control.

Opentrons publishes 9 APIs on the APIs.io network, including Attached Instruments API, Attached Modules API, Flex Deck Configuration API, and 6 more. Tagged areas include Lab Automation, Liquid Handling, Robotics, Biology, and Life Sciences.

The Opentrons catalog on APIs.io includes 1 Spectral governance ruleset.

Opentrons’ developer surface includes documentation, getting-started guide, product news, support, and 13 more developer resources.

🌐 Visit website 📡 Source on GitHub

35.0/100 thin ▼ -5.7 Agent 29/100 agent aware Full breakdown ↓
scored 2026-07-28 · rubric v0.6

AccessPaid

10 APIs

Lab AutomationLiquid HandlingRoboticsBiologyLife SciencesProtocol ManagementHardware ControlOpen Source

Kin Score

Kin Score How this is scored →
scored 2026-07-28 · rubric v0.6

Composite quality — 35.0/100 · thin

Contract Quality 12.1 / 25

Developer Ergonomics 4.8 / 20

Commercial Clarity 7.9 / 20

Operational Transparency 0.7 / 13

Governance 7.0 / 12

Discoverability 7.4 / 10

Agent readiness — 29/100 · agent aware

Machine-Readable Contract 18 / 18

Agentic Access Contract 10 / 10

MCP Server 0 / 12

Machine-Readable Auth 0 / 10

Idempotency 0 / 9

Stable Error Semantics 8 / 8

Request/Response Examples 0 / 7

Rate-Limit Signaling 7 / 7

Typed Event Surface 0 / 6

Agent Skills 0 / 5

Well-Known Catalog 0 / 4

Consent & Bot Identity 0 / 3

A2A Agent Card 0 / 8

Dry-Run / Simulate Mode 0 / 4

Improve this rating by publishing the missing artifacts — every area above can be raised, and the full rubric is at apis.io/rating/. This rating is computed from github.com/api-evangelist/opentrons: open an issue to ask a question, or submit a pull request to add artifacts. Want it done for you? Prioritized profiling — $2,500 →

APIs 10

Individual APIs this provider publishes, each with its own machine-readable definition.

Rate Limits 1

Documented rate limits and quota policies.

Opentrons Rate Limits

0 limits

RATE LIMITS

FinOps 1

Cost, billing, and metering signals for API financial operations.

JSON Schema 2

Standalone JSON Schema definitions for this provider's data models.

Opentrons Command

12 properties

JSON SCHEMA

Opentrons Run

13 properties

JSON SCHEMA

Examples 2

Example request and response payloads for these APIs.

AGENTIC

Resources

Get Started 1

Portal, sign-up, and the first successful call

GettingStarted

GettingStarted

Documentation 1

Reference material describing how the API behaves

Documentation

Documentation

Agent Surfaces 1

MCP servers, agent skills, and machine-readable catalogs

AgenticAccess

AgenticAccess

Build 3

SDKs, sample code, and the tooling you integrate with

GitHubOrganization

GitHubOrganization

ProtocolLibrary

ProtocolLibrary

LabwareLibrary

LabwareLibrary

Access & Security 1

Authentication, authorization, and security posture

DomainSecurity

DomainSecurity

Operate 3

Status, limits, changes, and where to get help

Support

Support

Contact

Contact

RateLimits

RateLimits

Commercial 2

Pricing, plans, and the legal terms of use

Plans

Plans

FinOps

FinOps

Company 3

The organization behind the API

Website

Website

News

News

LinkedIn

Other 2

Properties that don't map to a standard resource type

ProtocolDesigner

ProtocolDesigner

Source (apis.yml)

aid: opentrons
name: Opentrons
description: Opentrons is a lab automation platform providing a REST HTTP API and Python Protocol API for controlling liquid
  handling robots such as the Opentrons Flex and OT-2. Developers can programmatically manage protocols, control pipettes,
  run liquid handling workflows, manage labware, and integrate biology lab automation into their applications. The HTTP API
  operates on-robot over a local network and exposes OpenAPI-defined endpoints for protocol upload, run management, atomic
  liquid handling commands, and hardware control.
accessModel:
  pricing: paid
  onboarding: unknown
  trial: false
  try_now: false
  public: false
  label: Paid
  confidence: medium
  source:
  - plans
  generated: '2026-07-22'
  method: derived
image: https://kinlane-images.s3.amazonaws.com/shared/apis-json/icons/opentrons.png
url: https://raw.githubusercontent.com/api-evangelist/opentrons/refs/heads/main/apis.yml
created: '2026-06-13'
modified: '2026-06-13'
specificationVersion: '0.19'
tags:
- Lab Automation
- Liquid Handling
- Robotics
- Biology
- Life Sciences
- Protocol Management
- Hardware Control
- Open Source
apis:
- name: Opentrons Python Protocol API
  description: The Opentrons Python Protocol API is an open-source Python framework for writing automated biology lab protocols
    that run on Opentrons Flex and OT-2 robots. It provides programmatic control over pipettes, labware, deck configuration,
    hardware modules (thermocyclers, heater-shakers, temperature modules, magnetic modules, absorbance readers), and supports
    dynamic decision-making and custom integrations. Protocols are executed by the robot server and can be controlled via
    the HTTP API or Opentrons App.
  image: https://kinlane-images.s3.amazonaws.com/shared/apis-json/apis-json-logo.jpg
  humanURL: https://docs.opentrons.com/v2/
  baseURL: https://docs.opentrons.com
  tags:
  - Python
  - Protocol
  - Liquid Handling
  - Lab Automation
  - Hardware Modules
  - Open Source
  properties:
  - type: Documentation
    url: https://docs.opentrons.com/v2/
  - type: GettingStarted
    url: https://docs.opentrons.com/v2/new_quickstart.html
  - type: APIReference
    url: https://docs.opentrons.com/v2/new_protocol_api.html
  - type: ProtocolExamples
    url: https://docs.opentrons.com/v2/new_examples.html
  - type: GitHubRepository
    url: https://github.com/Opentrons/opentrons
  - type: PyPI
    url: https://pypi.org/project/opentrons/
  contact:
  - FN: Opentrons Support
    url: https://support.opentrons.com/
    email: support@opentrons.com
- aid: opentrons:opentrons-attached-instruments-api
  name: Opentrons Attached Instruments API
  description: Query attached pipettes and grippers
  humanURL: https://github.com/Opentrons/opentrons-integration-tools/tree/main/http-api
  baseURL: http://{ROBOT_IP}:31950
  tags:
  - Attached Instruments
  properties:
  - type: OpenAPI
    url: openapi/opentrons-attached-instruments-api-openapi.yml
  - type: Documentation
    url: https://github.com/Opentrons/opentrons-integration-tools/tree/main/http-api
  - type: Redoc
    url: http://{ROBOT_IP}:31950/redoc
  - type: GitHubRepository
    url: https://github.com/Opentrons/opentrons
  - type: IntegrationTools
    url: https://github.com/Opentrons/opentrons-integration-tools
- aid: opentrons:opentrons-attached-modules-api
  name: Opentrons Attached Modules API
  description: Query attached hardware modules
  humanURL: https://github.com/Opentrons/opentrons-integration-tools/tree/main/http-api
  baseURL: http://{ROBOT_IP}:31950
  tags:
  - Attached Modules
  properties:
  - type: OpenAPI
    url: openapi/opentrons-attached-modules-api-openapi.yml
  - type: Documentation
    url: https://github.com/Opentrons/opentrons-integration-tools/tree/main/http-api
  - type: Redoc
    url: http://{ROBOT_IP}:31950/redoc
  - type: GitHubRepository
    url: https://github.com/Opentrons/opentrons
  - type: IntegrationTools
    url: https://github.com/Opentrons/opentrons-integration-tools
- aid: opentrons:opentrons-flex-deck-configuration-api
  name: Opentrons Flex Deck Configuration API
  description: Configure the Flex robot deck
  humanURL: https://github.com/Opentrons/opentrons-integration-tools/tree/main/http-api
  baseURL: http://{ROBOT_IP}:31950
  tags:
  - Flex Deck Configuration
  properties:
  - type: OpenAPI
    url: openapi/opentrons-flex-deck-configuration-api-openapi.yml
  - type: Documentation
    url: https://github.com/Opentrons/opentrons-integration-tools/tree/main/http-api
  - type: Redoc
    url: http://{ROBOT_IP}:31950/redoc
  - type: GitHubRepository
    url: https://github.com/Opentrons/opentrons
  - type: IntegrationTools
    url: https://github.com/Opentrons/opentrons-integration-tools
- aid: opentrons:opentrons-health-api
  name: Opentrons Health API
  description: Robot server health and status endpoints
  humanURL: https://github.com/Opentrons/opentrons-integration-tools/tree/main/http-api
  baseURL: http://{ROBOT_IP}:31950
  tags:
  - Health
  properties:
  - type: OpenAPI
    url: openapi/opentrons-health-api-openapi.yml
  - type: Documentation
    url: https://github.com/Opentrons/opentrons-integration-tools/tree/main/http-api
  - type: Redoc
    url: http://{ROBOT_IP}:31950/redoc
  - type: GitHubRepository
    url: https://github.com/Opentrons/opentrons
  - type: IntegrationTools
    url: https://github.com/Opentrons/opentrons-integration-tools
- aid: opentrons:opentrons-protocol-management-api
  name: Opentrons Protocol Management API
  description: Upload, manage, and analyze protocols
  humanURL: https://github.com/Opentrons/opentrons-integration-tools/tree/main/http-api
  baseURL: http://{ROBOT_IP}:31950
  tags:
  - Protocol Management
  properties:
  - type: OpenAPI
    url: openapi/opentrons-protocol-management-api-openapi.yml
  - type: Documentation
    url: https://github.com/Opentrons/opentrons-integration-tools/tree/main/http-api
  - type: Redoc
    url: http://{ROBOT_IP}:31950/redoc
  - type: GitHubRepository
    url: https://github.com/Opentrons/opentrons
  - type: IntegrationTools
    url: https://github.com/Opentrons/opentrons-integration-tools
- aid: opentrons:opentrons-robot-api
  name: Opentrons Robot API
  description: Robot-level control including estop and door status
  humanURL: https://github.com/Opentrons/opentrons-integration-tools/tree/main/http-api
  baseURL: http://{ROBOT_IP}:31950
  tags:
  - Robot
  properties:
  - type: OpenAPI
    url: openapi/opentrons-robot-api-openapi.yml
  - type: Documentation
    url: https://github.com/Opentrons/opentrons-integration-tools/tree/main/http-api
  - type: Redoc
    url: http://{ROBOT_IP}:31950/redoc
  - type: GitHubRepository
    url: https://github.com/Opentrons/opentrons
  - type: IntegrationTools
    url: https://github.com/Opentrons/opentrons-integration-tools
- aid: opentrons:opentrons-run-management-api
  name: Opentrons Run Management API
  description: Create and control protocol runs
  humanURL: https://github.com/Opentrons/opentrons-integration-tools/tree/main/http-api
  baseURL: http://{ROBOT_IP}:31950
  tags:
  - Run Management
  properties:
  - type: OpenAPI
    url: openapi/opentrons-run-management-api-openapi.yml
  - type: Documentation
    url: https://github.com/Opentrons/opentrons-integration-tools/tree/main/http-api
  - type: Redoc
    url: http://{ROBOT_IP}:31950/redoc
  - type: GitHubRepository
    url: https://github.com/Opentrons/opentrons
  - type: IntegrationTools
    url: https://github.com/Opentrons/opentrons-integration-tools
- aid: opentrons:opentrons-simple-commands-api
  name: Opentrons Simple Commands API
  description: Stateless atomic liquid handling commands
  humanURL: https://github.com/Opentrons/opentrons-integration-tools/tree/main/http-api
  baseURL: http://{ROBOT_IP}:31950
  tags:
  - Simple Commands
  properties:
  - type: OpenAPI
    url: openapi/opentrons-simple-commands-api-openapi.yml
  - type: Documentation
    url: https://github.com/Opentrons/opentrons-integration-tools/tree/main/http-api
  - type: Redoc
    url: http://{ROBOT_IP}:31950/redoc
  - type: GitHubRepository
    url: https://github.com/Opentrons/opentrons
  - type: IntegrationTools
    url: https://github.com/Opentrons/opentrons-integration-tools
- aid: opentrons:opentrons-system-control-api
  name: Opentrons System Control API
  description: System time and robot control
  humanURL: https://github.com/Opentrons/opentrons-integration-tools/tree/main/http-api
  baseURL: http://{ROBOT_IP}:31950
  tags:
  - System Control
  properties:
  - type: OpenAPI
    url: openapi/opentrons-system-control-api-openapi.yml
  - type: Documentation
    url: https://github.com/Opentrons/opentrons-integration-tools/tree/main/http-api
  - type: Redoc
    url: http://{ROBOT_IP}:31950/redoc
  - type: GitHubRepository
    url: https://github.com/Opentrons/opentrons
  - type: IntegrationTools
    url: https://github.com/Opentrons/opentrons-integration-tools
common:
- type: AgenticAccess
  url: agentic-access/opentrons-agentic-access.yml
- type: DomainSecurity
  url: security/opentrons-domain-security.yml
- type: Website
  url: https://opentrons.com/
- type: Documentation
  url: https://docs.opentrons.com/
- type: GettingStarted
  url: https://opentrons.com/pythonapi
- type: News
  url: https://opentrons.com/about/news
- type: GitHubOrganization
  url: https://github.com/opentrons
- type: Support
  url: https://support.opentrons.com/
- type: Contact
  url: https://opentrons.com/contact-support
- type: LinkedIn
  url: https://www.linkedin.com/company/opentrons-labworks-inc.
- type: X
  url: https://twitter.com/opentrons
- type: ProtocolLibrary
  url: https://protocols.opentrons.com/
- type: LabwareLibrary
  url: https://labware.opentrons.com/
- type: ProtocolDesigner
  url: https://designer.opentrons.com/
- type: Plans
  url: plans/opentrons-plans-pricing.yml
- type: RateLimits
  url: rate-limits/opentrons-rate-limits.yml
- type: FinOps
  url: finops/opentrons-finops.yml
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com