Opentrons

Opentrons is a lab automation platform providing a REST HTTP API and Python Protocol API for controlling liquid handling robots such as the Opentrons Flex and OT-2. Developers can programmatically manage protocols, control pipettes, run liquid handling workflows, manage labware, and integrate biology lab automation into their applications. The HTTP API operates on-robot over a local network and exposes OpenAPI-defined endpoints for protocol upload, run management, atomic liquid handling commands, and hardware control.

Opentrons publishes 10 API contracts indexed on the APIs.io network, including Attached Instruments API, Attached Modules API, Flex Deck Configuration API, and 7 more. Tagged areas include Lab Automation, Liquid Handling, Robotics, Biology, and Life Sciences.

The Opentrons catalog on APIs.io includes 1 Spectral governance ruleset.

Opentrons’ developer surface includes documentation, getting-started guide, product news, support, and 18 more developer resources.

🌐 Visit website 📡 Profile data on GitHub

31.2/100 thin ▬ flat Agent 22/100 agent aware Front door AI 5/6 prominent Heartbeat 97/100 alive open core · Apache-2.0 Full breakdown ↓
scored 2026-11-06 · rubric v0.27.0 · Show this score on your site →

AccessPaid

1 published contract

Lab Automation Liquid Handling Robotics Biology Life SciencesProtocol ManagementHardware ControlOpen Source

Kin Score

Kin Score How this is scored →
scored 2026-11-06 · rubric v0.27.0

Composite quality — 31.2/100 · thin

Contract Quality 7.4 / 16

Developer Ergonomics 4.0 / 13

Access Clarity 1.0 / 13

Operational Transparency 1.6 / 8

Contract Governance 0.8 / 8

Discoverability 4.4 / 7

Regulatory Posture 0.7 / 15

Open Source Surface 6.5 / 10

Create-or-Update Ergonomics 0.0 / 10

Agent readiness — 22/100 · agent aware

Machine-Readable Contract 18 / 18

Agentic Access Contract 10 / 10

Documented Reversibility 0 / 6

MCP Server 0 / 12

Machine-Readable Auth 0 / 10

Idempotency 0 / 9

Stable Error Semantics 8 / 8

Request/Response Examples 0 / 7

Rate-Limit Signaling 7 / 7

Typed Event Surface 0 / 6

Agent Skills 0 / 5

Well-Known Catalog 0 / 4

Consent & Bot Identity 0 / 3

A2A Agent Card 0 / 8

Dry-Run / Simulate Mode 0 / 4

Delegated User Identity 0 / 6

Protected Resource Metadata 0 / 5

Registration Without a Human 0 / 6

Agentic Commerce Well-Known Document 0 / 5

Pagination 0 / 5

Distinct Operations 3 / 3

MCP Tool Quality 6 / 6

Regulatory Posture applies to this provider. Its tags matched the Health regime, so Regulatory Posture carries 15 points of the composite. If this regime is wrong for your business, say so on your provider repo — the applicability map is public and we will correct it.

Open Source Surface applies to this provider. This product is open source and we read its repository directly, so Open Source Surface carries 10 points of the composite. It is scored from what the repository actually publishes — a security policy, a contribution guide, a release history, a code of conduct — read live from the provider rather than inferred from our own catalog pointers. This facet adds; nothing was taken away to make room for it. An open-source project is not excused from the commercial facets, because exemption would strip it of the points it does earn. If we have the wrong repository, or this product is not open source, say so on your provider repo and we will drop the facet rather than have you publish against it.

Create-or-Update Ergonomics applies to this provider. This API accepts writes, so it carries 10 points of the composite. It is scored from the published contracts themselves: whether a caller can create-or-update in one call, whether the write accepts a key the caller already holds, and whether the response says which branch ran. Without that, every write needs a search-and-branch in front of it, and the first time that check is skipped a duplicate record is created. Scored against the observed mean rather than raw — a provider at the catalog average is unchanged by this facet, not penalised by it.

The six quality facets above are damped to 65 points between them, because both conditional facets apply and carry 35 points together. That is why each facet's contribution is shown against a damped maximum: raising a quality facet moves the composite by 65% of its nominal weight, not 100%. The full arithmetic is at apis.io/rating/.

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Agent readiness — checks not met, largest first (exact, from this profile):

MCP Server +12 pts — deployment.mode + probe verdict on the mcp/ manifest, not the pointer; an unprobed slug falls back to authorship
Machine-Readable Auth +10 pts — a served openid-configuration/oauth-authorization-server carrying `issuer` (served), else the securitySchemes class in the provider OpenAPIs — bound (mutualTLS, DPoP, Signature) > negotiable (oauth2 authorizationCode/clientCredentials, openIdConnect) > bearer (http bearer, apiKey)
Idempotency +9 pts — OpenAPI mutating operations declare an idempotency key — a header, a request-body property, or a named de-duplication token whose own description says so (verified); else common[].type matches /idempoten/i (documented)
A2A Agent Card +8 pts — a2a/-a2a.yml manifest, graded on conformance.grade against A2A 1.0.0
Request/Response Examples +7 pts — share of operations carrying request/response examples; else an Examples / Code Samples link
Registration Without a Human +6 pts — a `registration_endpoint` in the served RFC 8414 / OIDC discovery document

10 more unmet checks in the Agent Readiness table above.

Kin Score — facets with the most composite points still available (weight × headroom):

Access Clarity scores 7.9 — up to +18.4 composite points
Developer Ergonomics scores 31.0 — up to +13.8 composite points
Contract Quality scores 45.6 — up to +13.6 composite points

Each check links to what satisfies it. Publish the artifact, or tell us where it already lives, and the score moves on the next scoring run.

Improve this rating by publishing the missing artifacts — every area above can be raised, and the full rubric is at apis.io/rating/. Every facet and dimension name above is a link: it opens that measurement's own page — what it means, the exact checks that feed it, how the whole catalog distributes on it, and the providers at the top of it. This rating is computed from the provider profile at artifacts.apis.io/opentrons/apis.yml: open an issue on github.com/api-evangelist/opentrons to ask a question or point us at an artifact you publish. Submit an artifact on GitHub — free → Manage your own listing — the Influence plan, $499/mo →

Markets this provider is in provisional

The Kin Score Market layer reads a provider inside its market: its position, and how deep its integrations go. Depth is only comparable within a position. Provisional and unweighted: not part of the Kin Score or agent readiness.

Market	Position	Depth	Registered MCP server	Declares compatibility
IVD, Diagnostics and Surgical Devices (FDA / EU regulated device makers)	undeclared	-	-	-

Registered MCP server and declares compatibility are report only — not weighted. Undeclared means we found nothing we can read, so there is no number: we never infer integrations.

Standards implemented 1

Standards this provider implements or carries. De facto ones are profiled and measured by the API Commons; formal ones come from the standards directory and are linked by the provider's own tags. The evidence column says how each claim was established — not that it was made.

OpenAPI

measured — observed by APIs.io (published)

APIs 10

Individual APIs this provider publishes, each with its own machine-readable definition.

Opentrons Python Protocol API

The Opentrons Python Protocol API is an open-source Python framework for writing automated biology lab protocols that run on Opentrons Flex and OT-2 robots. It provides programm...

Opentrons Attached Instruments API

Query attached pipettes and grippers

Opentrons Attached Modules API

Query attached hardware modules

Opentrons Flex Deck Configuration API

Configure the Flex robot deck

Opentrons Health API

Robot server health and status endpoints

Opentrons Protocol Management API

Upload, manage, and analyze protocols

Opentrons Robot API

Robot-level control including estop and door status

Opentrons Run Management API

Create and control protocol runs

Opentrons Simple Commands API

Stateless atomic liquid handling commands

Opentrons System Control API

System time and robot control

Scroll for all 10

Open Collections 9

Open, tool-agnostic API collections (OpenAPI-derived and Bruno).

Opentrons HTTP Attached Instruments API

OPEN COLLECTION

Opentrons HTTP Attached Instruments Attached Modules API

OPEN COLLECTION

Opentrons HTTP Attached Instruments Flex Deck Configuration API

OPEN COLLECTION

Opentrons HTTP Attached Instruments Health API

OPEN COLLECTION

Opentrons HTTP Attached Instruments Protocol Management API

OPEN COLLECTION

Opentrons HTTP Attached Instruments Robot API

OPEN COLLECTION

Opentrons HTTP Attached Instruments Run Management API

OPEN COLLECTION

Opentrons HTTP Attached Instruments Simple Commands API

OPEN COLLECTION

Opentrons HTTP Attached Instruments System Control API

OPEN COLLECTION

Scroll for all 9

Opentrons API pricing

Not yet checked against Opentrons's own pricing page. Compiled by API Evangelist; confirm before you rely on a figure.

Plan	Price
Opentrons Flex Robot	—
Opentrons OT-2 Robot	—
Flex NGS Workstation	—
Custom Protocol Development	—

Plan details, limits and sources →

Pricing Plans 1

Published pricing tiers and plan structures.

Opentrons Plans Pricing

4 plans

PLANS

Rate Limits 1

Documented rate limits and quota policies.

Opentrons Rate Limits

0 limits

RATE LIMITS

Service Levels 1

Uptime the provider promises or reports, as SLA4OAI. Read from its own pages; APIs.io runs no monitors.

Opentrons

SLA

FinOps 1

Cost, billing, and metering signals for API financial operations.

Opentrons Finops

FINOPS

Spectral Rules 1

Spectral governance rulesets for linting and validating these APIs.

Opentrons — jsonschema rules

6 rules · 4 warnings 2 info

SPECTRAL

JSON Schema 2

Standalone JSON Schema definitions for this provider's data models.

Opentrons Command

12 properties

JSON SCHEMA

Opentrons Run

13 properties

JSON SCHEMA

Examples 2

Example request and response payloads for these APIs.

Atomic Liquid Handling

3 fields

EXAMPLE

Create Run From Protocol

4 fields

EXAMPLE

Security Posture 1

Authentication, domain security, vulnerability disclosure, and trust-center signals.

Opentrons Domain Security

TLSv1.3 · DMARC

SECURITY

Agentic Access 1

Recommended x-agentic-access execution contracts for AI agents.

Opentrons Agentic Access

29 operations · 12 acting · 3 human-in-the-loop

29 operations · 12 acting

AGENTIC

Resources

Get Started 1

Portal, sign-up, and the first successful call

GettingStarted

GettingStarted

Documentation 2

Reference material describing how the API behaves

ContributionGuide

ContributionGuide

Documentation

Documentation

Agent Surfaces 1

MCP servers, agent skills, and machine-readable catalogs

AgenticAccess

AgenticAccess

Build 4

SDKs, sample code, and the tooling you integrate with

CodeOfConduct

CodeOfConduct

GitHubOrganization

GitHubOrganization

ProtocolLibrary

ProtocolLibrary

LabwareLibrary

LabwareLibrary

Access & Security 1

Authentication, authorization, and security posture

DomainSecurity

DomainSecurity

Operate 5

Status, limits, changes, and where to get help

IssueTracker

Releases

Support

Contact

RateLimits

Commercial 3

Pricing, plans, and the legal terms of use

License

License

Plans

Plans

FinOps

FinOps

Company 3

The organization behind the API

Website

Website

News

News

LinkedIn

Other 2

Properties that don't map to a standard resource type

ProtocolDesigner

ProtocolDesigner

Source (apis.yml)

aid: opentrons
name: Opentrons
description: Opentrons is a lab automation platform providing a REST HTTP API and Python Protocol API for controlling liquid
  handling robots such as the Opentrons Flex and OT-2. Developers can programmatically manage protocols, control pipettes,
  run liquid handling workflows, manage labware, and integrate biology lab automation into their applications. The HTTP API
  operates on-robot over a local network and exposes OpenAPI-defined endpoints for protocol upload, run management, atomic
  liquid handling commands, and hardware control.
deliveryModel:
  model: open-core
  license: Apache-2.0
  open_source: true
  commercial: true
  callable_host: false
  label: Open core · an OSS project plus a commercial hosted product
  confidence: high
  source:
  - license
  - openapi
  - pricing
  generated: '2026-08-28'
  method: derived
accessModel:
  pricing: paid
  onboarding: unknown
  trial: false
  try_now: false
  public: false
  label: Paid
  confidence: low
  source:
  - plans
  - security
  generated: '2026-11-06'
  method: derived
image: https://kinlane-images.s3.amazonaws.com/shared/apis-json/icons/opentrons.png
url: https://raw.githubusercontent.com/api-evangelist/opentrons/refs/heads/main/apis.yml
created: '2026-06-13'
modified: '2026-06-13'
specificationVersion: '0.23'
x-docs-platform: mkdocs
x-docs-platform-confidence: medium
x-docs-platform-checked: 2026-10-04
tags:
- Lab Automation
- Liquid Handling
- Robotics
- Biology
- Life Sciences
- Protocol Management
- Hardware Control
- Open Source
tags_raw:
- Lab Automation
- Liquid Handling
- Robotics
- Biology
- Life Sciences
- Protocol Management
- Hardware Control
- Open Source
- Open-Source
apis:
- name: Opentrons Python Protocol API
  description: The Opentrons Python Protocol API is an open-source Python framework for writing automated biology lab protocols
    that run on Opentrons Flex and OT-2 robots. It provides programmatic control over pipettes, labware, deck configuration,
    hardware modules (thermocyclers, heater-shakers, temperature modules, magnetic modules, absorbance readers), and supports
    dynamic decision-making and custom integrations. Protocols are executed by the robot server and can be controlled via
    the HTTP API or Opentrons App.
  image: https://kinlane-images.s3.amazonaws.com/shared/apis-json/apis-json-logo.jpg
  humanURL: https://docs.opentrons.com/v2/
  baseURL: https://docs.opentrons.com
  tags:
  - Python
  - Protocol
  - Liquid Handling
  - Lab Automation
  - Hardware Modules
  - Open Source
  tags_raw:
  - Python
  - Protocol
  - Liquid Handling
  - Lab Automation
  - Hardware Modules
  - Open Source
  - Open-Source
  properties:
  - type: Documentation
    url: https://docs.opentrons.com/v2/
  - type: GettingStarted
    url: https://docs.opentrons.com/v2/new_quickstart.html
  - type: APIReference
    url: https://docs.opentrons.com/v2/new_protocol_api.html
  - type: ProtocolExamples
    url: https://docs.opentrons.com/v2/new_examples.html
  - type: GitHubRepository
    url: https://github.com/Opentrons/opentrons
  - type: PyPI
    url: https://pypi.org/project/opentrons/
  contact:
  - FN: Opentrons Support
    url: https://support.opentrons.com/
    email: support@opentrons.com
- aid: opentrons:opentrons-attached-instruments-api
  name: Opentrons Attached Instruments API
  description: Query attached pipettes and grippers
  humanURL: https://github.com/Opentrons/opentrons-integration-tools/tree/main/http-api
  baseURL: http://{ROBOT_IP}:31950
  tags:
  - Attached Instruments
  properties:
  - type: OpenAPI
    url: openapi/opentrons-attached-instruments-api-openapi.yml
  - type: Documentation
    url: https://github.com/Opentrons/opentrons-integration-tools/tree/main/http-api
  - type: Redoc
    url: http://{ROBOT_IP}:31950/redoc
  - type: GitHubRepository
    url: https://github.com/Opentrons/opentrons
  - type: IntegrationTools
    url: https://github.com/Opentrons/opentrons-integration-tools
- aid: opentrons:opentrons-attached-modules-api
  name: Opentrons Attached Modules API
  description: Query attached hardware modules
  humanURL: https://github.com/Opentrons/opentrons-integration-tools/tree/main/http-api
  baseURL: http://{ROBOT_IP}:31950
  tags:
  - Attached Modules
  properties:
  - type: OpenAPI
    url: openapi/opentrons-attached-modules-api-openapi.yml
  - type: Documentation
    url: https://github.com/Opentrons/opentrons-integration-tools/tree/main/http-api
  - type: Redoc
    url: http://{ROBOT_IP}:31950/redoc
  - type: GitHubRepository
    url: https://github.com/Opentrons/opentrons
  - type: IntegrationTools
    url: https://github.com/Opentrons/opentrons-integration-tools
- aid: opentrons:opentrons-flex-deck-configuration-api
  name: Opentrons Flex Deck Configuration API
  description: Configure the Flex robot deck
  humanURL: https://github.com/Opentrons/opentrons-integration-tools/tree/main/http-api
  baseURL: http://{ROBOT_IP}:31950
  tags:
  - Flex Deck Configuration
  properties:
  - type: OpenAPI
    url: openapi/opentrons-flex-deck-configuration-api-openapi.yml
  - type: Documentation
    url: https://github.com/Opentrons/opentrons-integration-tools/tree/main/http-api
  - type: Redoc
    url: http://{ROBOT_IP}:31950/redoc
  - type: GitHubRepository
    url: https://github.com/Opentrons/opentrons
  - type: IntegrationTools
    url: https://github.com/Opentrons/opentrons-integration-tools
- aid: opentrons:opentrons-health-api
  name: Opentrons Health API
  description: Robot server health and status endpoints
  humanURL: https://github.com/Opentrons/opentrons-integration-tools/tree/main/http-api
  baseURL: http://{ROBOT_IP}:31950
  tags:
  - Health
  properties:
  - type: OpenAPI
    url: openapi/opentrons-health-api-openapi.yml
  - type: Documentation
    url: https://github.com/Opentrons/opentrons-integration-tools/tree/main/http-api
  - type: Redoc
    url: http://{ROBOT_IP}:31950/redoc
  - type: GitHubRepository
    url: https://github.com/Opentrons/opentrons
  - type: IntegrationTools
    url: https://github.com/Opentrons/opentrons-integration-tools
- aid: opentrons:opentrons-protocol-management-api
  name: Opentrons Protocol Management API
  description: Upload, manage, and analyze protocols
  humanURL: https://github.com/Opentrons/opentrons-integration-tools/tree/main/http-api
  baseURL: http://{ROBOT_IP}:31950
  tags:
  - Protocol Management
  properties:
  - type: OpenAPI
    url: openapi/opentrons-protocol-management-api-openapi.yml
  - type: Documentation
    url: https://github.com/Opentrons/opentrons-integration-tools/tree/main/http-api
  - type: Redoc
    url: http://{ROBOT_IP}:31950/redoc
  - type: GitHubRepository
    url: https://github.com/Opentrons/opentrons
  - type: IntegrationTools
    url: https://github.com/Opentrons/opentrons-integration-tools
- aid: opentrons:opentrons-robot-api
  name: Opentrons Robot API
  description: Robot-level control including estop and door status
  humanURL: https://github.com/Opentrons/opentrons-integration-tools/tree/main/http-api
  baseURL: http://{ROBOT_IP}:31950
  tags:
  - Robot
  properties:
  - type: OpenAPI
    url: openapi/opentrons-robot-api-openapi.yml
  - type: Documentation
    url: https://github.com/Opentrons/opentrons-integration-tools/tree/main/http-api
  - type: Redoc
    url: http://{ROBOT_IP}:31950/redoc
  - type: GitHubRepository
    url: https://github.com/Opentrons/opentrons
  - type: IntegrationTools
    url: https://github.com/Opentrons/opentrons-integration-tools
- aid: opentrons:opentrons-run-management-api
  name: Opentrons Run Management API
  description: Create and control protocol runs
  humanURL: https://github.com/Opentrons/opentrons-integration-tools/tree/main/http-api
  baseURL: http://{ROBOT_IP}:31950
  tags:
  - Run Management
  properties:
  - type: OpenAPI
    url: openapi/opentrons-run-management-api-openapi.yml
  - type: Documentation
    url: https://github.com/Opentrons/opentrons-integration-tools/tree/main/http-api
  - type: Redoc
    url: http://{ROBOT_IP}:31950/redoc
  - type: GitHubRepository
    url: https://github.com/Opentrons/opentrons
  - type: IntegrationTools
    url: https://github.com/Opentrons/opentrons-integration-tools
- aid: opentrons:opentrons-simple-commands-api
  name: Opentrons Simple Commands API
  description: Stateless atomic liquid handling commands
  humanURL: https://github.com/Opentrons/opentrons-integration-tools/tree/main/http-api
  baseURL: http://{ROBOT_IP}:31950
  tags:
  - Simple Commands
  properties:
  - type: OpenAPI
    url: openapi/opentrons-simple-commands-api-openapi.yml
  - type: Documentation
    url: https://github.com/Opentrons/opentrons-integration-tools/tree/main/http-api
  - type: Redoc
    url: http://{ROBOT_IP}:31950/redoc
  - type: GitHubRepository
    url: https://github.com/Opentrons/opentrons
  - type: IntegrationTools
    url: https://github.com/Opentrons/opentrons-integration-tools
- aid: opentrons:opentrons-system-control-api
  name: Opentrons System Control API
  description: System time and robot control
  humanURL: https://github.com/Opentrons/opentrons-integration-tools/tree/main/http-api
  baseURL: http://{ROBOT_IP}:31950
  tags:
  - System Control
  properties:
  - type: OpenAPI
    url: openapi/opentrons-system-control-api-openapi.yml
  - type: Documentation
    url: https://github.com/Opentrons/opentrons-integration-tools/tree/main/http-api
  - type: Redoc
    url: http://{ROBOT_IP}:31950/redoc
  - type: GitHubRepository
    url: https://github.com/Opentrons/opentrons
  - type: IntegrationTools
    url: https://github.com/Opentrons/opentrons-integration-tools
common:
- type: IssueTracker
  url: https://github.com/Opentrons/opentrons/issues
- type: Releases
  url: https://github.com/Opentrons/opentrons/releases
- type: CodeOfConduct
  url: https://github.com/Opentrons/.github/blob/main/CODE_OF_CONDUCT.md
- type: ContributionGuide
  url: https://github.com/Opentrons/opentrons/blob/edge/CONTRIBUTING.md
- type: License
  name: Apache-2.0
  url: https://github.com/Opentrons/opentrons/blob/edge/LICENSE
- type: AgenticAccess
  url: agentic-access/opentrons-agentic-access.yml
- type: DomainSecurity
  url: security/opentrons-domain-security.yml
- type: Website
  url: https://opentrons.com/
- type: Documentation
  url: https://docs.opentrons.com/
- type: GettingStarted
  url: https://opentrons.com/pythonapi
- type: News
  url: https://opentrons.com/about/news
- type: GitHubOrganization
  url: https://github.com/opentrons
- type: Support
  url: https://support.opentrons.com/
- type: Contact
  url: https://opentrons.com/contact-support
- type: LinkedIn
  url: https://www.linkedin.com/company/opentrons-labworks-inc.
- type: X
  url: https://twitter.com/opentrons
- type: ProtocolLibrary
  url: https://protocols.opentrons.com/
- type: LabwareLibrary
  url: https://labware.opentrons.com/
- type: ProtocolDesigner
  url: https://designer.opentrons.com/
- type: Plans
  url: plans/opentrons-plans-pricing.yml
- type: RateLimits
  url: rate-limits/opentrons-rate-limits.yml
- type: FinOps
  url: finops/opentrons-finops.yml
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com

Opentrons API — frequently asked questions

Does Opentrons have an API?

Yes. APIs.io lists 10 APIs from Opentrons, including Opentrons Python Protocol API, Opentrons Attached Instruments API and Opentrons Attached Modules API, and 7 more.

Is there an OpenAPI specification for the Opentrons API?

Yes. APIs.io indexes 9 OpenAPI specifications for Opentrons, each linked for download from this page.

How much does the Opentrons API cost?

APIs.io lists 4 pricing plans for Opentrons, with each plan's price, limits and inclusions under Pricing on this page.

Is the Opentrons API ready for AI agents?

Opentrons has a Kin Score of 31.2 out of 100 (thin) and an Agent Readiness score of 22.0 (agent-aware), scored by API Evangelist on 2026-11-06.

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