OnKure Therapeutics website screenshot

OnKure Therapeutics

OnKure Therapeutics (Nasdaq: OKUR) is a publicly traded, clinical-stage biopharmaceutical company headquartered in Boulder, Colorado, developing precision medicines for people with cancer. The company designs mutant-selective small-molecule inhibitors against oncogenic drivers in the PI3K pathway; its lead program OKI-219 is a selective PI3K-alpha H1047R inhibitor in clinical development, with additional discovery programs targeting further PI3K-alpha mutations. OnKure became publicly listed through its 2024 combination with Reneo Pharmaceuticals. It is a therapeutics developer rather than a software vendor: it operates a corporate and investor relations web presence and publishes no developer program, public API, SDK, or machine-readable API contract.

OnKure Therapeutics is profiled on the APIs.io network. Tagged areas include Company, Biotechnology, Pharmaceuticals, Oncology, and Precision Medicine.

OnKure Therapeutics’ developer surface includes support, product news, and 9 more developer resources.

10.0/100 minimal ▬ flat Agent 0/100 human only saas Full breakdown ↓
scored 2026-09-02 · rubric v0.18.0
0 APIs
CompanyBiotechnologyPharmaceuticalsOncologyPrecision MedicineClinical TrialsLife SciencesDrug DiscoveryPublicly Traded

Kin Score

Kin Score Kin Score How this is scored →
scored 2026-09-02 · rubric v0.18.0
Regulatory Posture applies to this provider. Its tags matched the Health regime, so Regulatory Posture carries 15 points of the composite. If this regime is wrong for your business, say so on your provider repo — the applicability map is public and we will correct it.
The six quality facets above are damped to 85 points between them, because the conditional facet above carries the other 15. That is why each facet's contribution is shown against a damped maximum: raising a quality facet moves the composite by 85% of its nominal weight, not 100%. The full arithmetic is at apis.io/rating/.
Improve this rating by publishing the missing artifacts — every area above can be raised, and the full rubric is at apis.io/rating/. Every facet and dimension name above is a link: it opens that measurement's own page — what it means, the exact checks that feed it, how the whole catalog distributes on it, and the providers at the top of it. This rating is computed from github.com/api-evangelist/onkure-therapeutics: open an issue to ask a question, or submit a pull request to add artifacts. Submit an artifact on GitHub — free → Manage your own listing — the Influence plan, $499/mo →

Security Posture 1

Authentication, domain security, vulnerability disclosure, and trust-center signals.

Onkure Therapeutics Domain Security

TLSv1.3 · DMARC

SECURITY

Resources

Agent Surfaces 1

MCP servers, agent skills, and machine-readable catalogs

Access & Security 1

Authentication, authorization, and security posture

Operate 1

Status, limits, changes, and where to get help

Commercial 2

Pricing, plans, and the legal terms of use

Company 6

The organization behind the API

Source (apis.yml)

apis.yml Raw ↑
aid: onkure-therapeutics
name: OnKure Therapeutics
description: 'OnKure Therapeutics (Nasdaq: OKUR) is a publicly traded, clinical-stage biopharmaceutical company headquartered
  in Boulder, Colorado, developing precision medicines for people with cancer. The company designs mutant-selective small-molecule
  inhibitors against oncogenic drivers in the PI3K pathway; its lead program OKI-219 is a selective PI3K-alpha H1047R inhibitor
  in clinical development, with additional discovery programs targeting further PI3K-alpha mutations. OnKure became publicly
  listed through its 2024 combination with Reneo Pharmaceuticals. It is a therapeutics developer rather than a software vendor:
  it operates a corporate and investor relations web presence and publishes no developer program, public API, SDK, or machine-readable
  API contract.'
url: https://raw.githubusercontent.com/api-evangelist/onkure-therapeutics/refs/heads/main/apis.yml
x-type: company
x-source: harvest:secondary-market
x-tier: profiled
x-tier-reason: enrichment pass completed; no API surface published
deliveryModel:
  model: saas
  open_source: false
  commercial: true
  callable_host: false
  label: Hosted service · you call their endpoint
  confidence: medium
  source:
  - pricing
  generated: '2026-08-28'
  method: derived
accessModel:
  pricing: unknown
  onboarding: unknown
  trial: false
  try_now: false
  public: false
  label: Unknown
  confidence: low
  source:
  - security
  generated: '2026-09-02'
  method: derived
specificationVersion: '0.20'
created: '2026-08-26'
modified: '2026-08-26'
tags:
- Company
- Biotechnology
- Pharmaceuticals
- Oncology
- Precision Medicine
- Clinical Trials
- Life Sciences
- Drug Discovery
- Publicly Traded
apis: []
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: DomainSecurity
  url: security/onkure-therapeutics-domain-security.yml
- type: Website
  url: https://onkuretherapeutics.com/
- type: About
  url: https://onkuretherapeutics.com/about/company/
- type: Support
  url: https://onkuretherapeutics.com/contact/
- type: TermsOfService
  url: https://onkuretherapeutics.com/terms-of-use/
- type: PrivacyPolicy
  url: https://onkuretherapeutics.com/privacy-policy/
- type: InvestorRelations
  url: https://investors.onkuretherapeutics.com/
- type: News
  url: https://investors.onkuretherapeutics.com/news-events/news-releases
- type: LinkedIn
  url: https://www.linkedin.com/company/onkure-tx/
- type: Twitter
  url: https://twitter.com/OnKureTx
- type: WellKnown-Probe
  url: well-known/onkure-therapeutics-well-known.yml
image: https://onkuretherapeutics.com/wp-content/uploads/logo-onkure-color-min.png
x-enrichment:
  date: '2026-08-26'
  status: minimal
  artifacts_added: 2
  pass: local-v1
x-coverage:
  state: none
  reason: not-a-software-company
  detail: 'OnKure is a clinical-stage biopharmaceutical company whose product is a drug candidate (OKI-219), not software:
    its onkuretherapeutics.com site is a WordPress marketing presence with only About/Pipeline/Careers/Contact sections, the
    sole machine-readable surface is the default WordPress /wp-json/ CMS endpoint exposing Yoast, Wordfence and Redirection
    plugin routes rather than any OnKure API, and api/developer/docs/graphql/mcp subdomains do not resolve in DNS.'
  evidence:
  - url: https://onkuretherapeutics.com/openapi.json
    status: 404
  - url: https://onkuretherapeutics.com/.well-known/agent-card.json
    status: 404
  - url: https://onkuretherapeutics.com/llms.txt
    status: 404
  - url: https://api.onkuretherapeutics.com/openapi.json
    status: 0
  - url: https://onkuretherapeutics.com/wp-json/
    status: 200
  checked: '2026-08-26'

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