Metagenomi

Metagenomi Therapeutics, Inc. (Nasdaq: MGX) is an Emeryville, California clinical-stage genetic medicines company that mines metagenomics — DNA sequenced directly from environmental microbial communities — together with machine learning to discover novel gene-editing machinery from otherwise unknown organisms, then engineers it into in vivo genome-editing therapies. Its published toolbox spans five system classes: programmable CRISPR nucleases, ultra-small nucleases that package into a single AAV vector, base editors the company describes as "the smallest CRISPR base editors known", RNA Mediated Integration Systems (RIGS) for template-encoded edits, and CRISPR Associated Transposases (CASTs) for gene integrations exceeding 10,000 base pairs. The company completed its initial public offering on the Nasdaq Global Select Market in February 2024 at $15.00 per share and partners with Ionis Pharmaceuticals on gene-editing programs including ApoC-III, transthyretin (TTR) and angiotensinogen (AGT). Metagenomi sells therapeutics, not software: metagenomi.co is a seven-page Craft CMS marketing site with no developer program, no API, no SDK and no machine-readable specification of any kind. Its GitHub organization is real and first-party but publishes zero public repositories, and its only first-party software package — the `metagenomi` PyPI library of internal Docker helper scripts — has not shipped a release since July 2019.

Metagenomi is profiled on the APIs.io network. Tagged areas include Company, Biotechnology, Pharmaceuticals, Gene Editing, and CRISPR.

Metagenomi’s developer surface includes engineering blog and 10 more developer resources.

🌐 Visit website 📡 Source on GitHub
9.9/100 minimal ▬ flat Agent 0/100 human only saas Full breakdown ↓
scored 2026-09-02 · rubric v0.18.0
0 APIs
CompanyBiotechnologyPharmaceuticalsGene EditingCRISPRGenetic MedicineGenomicsDrug DiscoveryLife SciencesMachine-LearningMetagenomicsResearch

Kin Score

Kin Score Kin Score How this is scored →
scored 2026-09-02 · rubric v0.18.0
Composite quality — 9.9/100 · minimal
Contract Quality 0.0 / 21
Developer Ergonomics 0.4 / 17
Access Clarity 3.6 / 17
Operational Transparency 0.3 / 11
Contract Governance 0.0 / 10
Discoverability 4.3 / 9
Regulatory Posture 2.6 / 15
Agent readiness — 0/100 · human only
Machine-Readable Contract 0 / 18
Agentic Access Contract 0 / 10
Documented Reversibility 0 / 6
MCP Server 0 / 12
Machine-Readable Auth 0 / 10
Idempotency 0 / 9
Stable Error Semantics 0 / 8
Request/Response Examples 0 / 7
Rate-Limit Signaling 0 / 7
Typed Event Surface 0 / 6
Agent Skills 0 / 5
Well-Known Catalog 0 / 4
Consent & Bot Identity 0 / 3
A2A Agent Card 0 / 8
Dry-Run / Simulate Mode 0 / 4
Delegated User Identity 0 / 6
Protected Resource Metadata 0 / 5
Registration Without a Human 0 / 6
Agentic Commerce Surface 0 / 5
Regulatory Posture applies to this provider. Its tags matched the Health regime, so Regulatory Posture carries 15 points of the composite. If this regime is wrong for your business, say so on your provider repo — the applicability map is public and we will correct it.
The six quality facets above are damped to 85 points between them, because the conditional facet above carries the other 15. That is why each facet's contribution is shown against a damped maximum: raising a quality facet moves the composite by 85% of its nominal weight, not 100%. The full arithmetic is at apis.io/rating/.
Improve this rating by publishing the missing artifacts — every area above can be raised, and the full rubric is at apis.io/rating/. Every facet and dimension name above is a link: it opens that measurement's own page — what it means, the exact checks that feed it, how the whole catalog distributes on it, and the providers at the top of it. This rating is computed from github.com/api-evangelist/metagenomi: open an issue to ask a question, or submit a pull request to add artifacts. Submit an artifact on GitHub — free → Manage your own listing — the Influence plan, $499/mo →

Security Posture 1

Authentication, domain security, vulnerability disclosure, and trust-center signals.

Metagenomi Domain Security

TLSv1.3 · HSTS · DMARC

SECURITY

Resources

Agent Surfaces 1

MCP servers, agent skills, and machine-readable catalogs

LLMsTxt
LLMsTxt

Build 2

SDKs, sample code, and the tooling you integrate with

GitHubOrganization
GitHubOrganization
 Packages
Packages

Access & Security 1

Authentication, authorization, and security posture

DomainSecurity
DomainSecurity

Commercial 2

Pricing, plans, and the legal terms of use

TermsOfService
TermsOfService
 PrivacyPolicy
PrivacyPolicy

Company 4

The organization behind the API

Website
Website
 InvestorRelations
InvestorRelations
 Blog
Blog
 Careers
Careers

Other 1

Properties that don't map to a standard resource type

SecondaryMarket
SecondaryMarket

Source (apis.yml)

apis.yml Raw ↑ 
aid: metagenomi
name: Metagenomi
description: 'Metagenomi Therapeutics, Inc. (Nasdaq: MGX) is an Emeryville, California clinical-stage genetic medicines company
  that mines metagenomics — DNA sequenced directly from environmental microbial communities — together with machine learning
  to discover novel gene-editing machinery from otherwise unknown organisms, then engineers it into in vivo genome-editing
  therapies. Its published toolbox spans five system classes: programmable CRISPR nucleases, ultra-small nucleases that package
  into a single AAV vector, base editors the company describes as "the smallest CRISPR base editors known", RNA Mediated Integration
  Systems (RIGS) for template-encoded edits, and CRISPR Associated Transposases (CASTs) for gene integrations exceeding 10,000
  base pairs. The company completed its initial public offering on the Nasdaq Global Select Market in February 2024 at $15.00
  per share and partners with Ionis Pharmaceuticals on gene-editing programs including ApoC-III, transthyretin (TTR) and angiotensinogen
  (AGT). Metagenomi sells therapeutics, not software: metagenomi.co is a seven-page Craft CMS marketing site with no developer
  program, no API, no SDK and no machine-readable specification of any kind. Its GitHub organization is real and first-party
  but publishes zero public repositories, and its only first-party software package — the `metagenomi` PyPI library of internal
  Docker helper scripts — has not shipped a release since July 2019.'
url: https://raw.githubusercontent.com/api-evangelist/metagenomi/refs/heads/main/apis.yml
deliveryModel:
  model: saas
  open_source: false
  commercial: true
  callable_host: false
  label: Hosted service · you call their endpoint
  confidence: medium
  source:
  - pricing
  generated: '2026-08-28'
  method: derived
accessModel:
  pricing: unknown
  onboarding: unknown
  trial: false
  try_now: false
  public: false
  label: Unknown
  confidence: low
  source:
  - security
  generated: '2026-09-02'
  method: derived
image: https://metagenomi.imgix.net/metagenomi-seo-image.png?auto=compress%2Cformat&crop=focalpoint&fit=crop&fp-x=0.5&fp-y=0.5&h=630&q=60&w=1200&s=dcdcd18b56fbe733f9ccf2ad0dd474dd
x-type: company
x-source: harvest:secondary-market
x-tier: profiled
x-tier-reason: enrichment-pipeline
specificationVersion: '0.23'
created: '2026-08-25'
modified: '2026-08-25'
tags:
- Company
- Biotechnology
- Pharmaceuticals
- Gene Editing
- CRISPR
- Genetic Medicine
- Genomics
- Drug Discovery
- Life Sciences
- Machine-Learning
- Metagenomics
- Research
tags_raw:
- Company
- Biotechnology
- Pharmaceuticals
- Gene Editing
- CRISPR
- Genetic Medicine
- Genomics
- Drug Discovery
- Life Sciences
- Machine Learning
- Metagenomics
- Research
apis: []
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: Website
  url: https://metagenomi.co/
- type: InvestorRelations
  url: https://ir.metagenomi.co/
- type: Blog
  url: https://metagenomi.co/news
- type: Careers
  url: https://metagenomi.co/careers
- type: GitHubOrganization
  url: https://github.com/Metagenomi
- type: TermsOfService
  url: https://metagenomi.co/terms-of-use
- type: PrivacyPolicy
  url: https://metagenomi.co/privacy-policy
- type: SecondaryMarket
  url: https://forgeglobal.com/metagenomi_stock/
- type: Packages
  url: packages/metagenomi-packages.yml
- type: DomainSecurity
  url: security/metagenomi-domain-security.yml
- type: LLMsTxt
  url: llms/metagenomi-llms.txt
x-enrichment:
  date: '2026-08-25'
  status: minimal
  artifacts_added: 4
  pass: local-v1
x-coverage:
  state: none
  reason: not-a-software-company
  detail: 'Metagenomi (Nasdaq: MGX) is a clinical-stage in vivo genome-editing biotech whose product is a drug pipeline, not
    software — metagenomi.co is a seven-page Craft CMS marketing site whose own sitemap enumerates the entire property (about-us,
    research, novel-proprietary-systems, pipeline, terms-of-use, privacy-policy, careers) with no developer page of any kind,
    every spec and /.well-known/ path returns a real 404, and api./dev./developer./docs./app./platform.metagenomi.co do not
    resolve at all; the company''s first-party GitHub organization is genuine but holds zero public repositories, and its
    only published package — `metagenomi` on PyPI, internal Docker helper scripts rather than an API client — last shipped
    a release on 2019-07-31.'
  evidence:
  - url: https://metagenomi.co/
    status: 200
  - url: https://metagenomi.co/openapi.json
    status: 404
  - url: https://metagenomi.co/graphql
    status: 404
  - url: https://metagenomi.co/llms.txt
    status: 404
  - url: https://metagenomi.co/.well-known/agent-card.json
    status: 404
  - url: https://metagenomi.co/.well-known/security.txt
    status: 404
  - url: https://metagenomi.co/sitemaps-1-section-pages-1-sitemap.xml
    status: 200
  - url: https://ir.metagenomi.co/llms.txt
    status: 404
  - url: https://api.github.com/users/Metagenomi/repos
    status: 200
  - url: https://pypi.org/pypi/metagenomi/json
    status: 200
  checked: '2026-08-25'

Work with this as data

Every provider here is available over the APIs.io API and to AI agents over MCP.

MCP server

One button, every client — Claude, Cursor, VS Code and the rest.

https://apis.io/mcp

Tools for providers

9 MCP tools reach this
  • find_providersBrowse and filter every provider in the catalog.
  • get_provider_artifactsEvery artifact this provider publishes, grouped by type.
  • get_provider_operationsEvery operation across all of their OpenAPIs — one call instead of parsing every spec.
  • get_provider_toolsEvery MCP tool they ship, with the operation each wraps.
  • get_provider_evidenceHow each part of their score was established. Free — the basis for a claim should not sit behind it.
  • get_provider_ratingPRO — composite, band, trend and facet scores.
  • apis_io_searchSTART HERE — APIs, providers and tags for one query, each with its total.
  • resolveTurn a domain, URL or GitHub org into the provider it belongs to.
  • find_cohortsEvery scored population of providers in the catalog.
All 92 tools →

Call it yourself

curl for this page
This provider 
curl "https://apis.io/api/v1/providers/metagenomi"
All providers 
curl "https://apis.io/api/v1/providers?limit=25"
Every operation they expose 
curl "https://apis.io/api/v1/providers/metagenomi/operations?limit=25"
How their score was established 
curl "https://apis.io/api/v1/providers/metagenomi/evidence"

Discovery needs no key. Ratings and market analysis are Pro.

Get an API key

Free tier, no email required.

GitHub Google LinkedIn

A second provider on the same verified email joins the account you already have.