MBrace Therapeutics

MBrace Therapeutics is a privately held, clinical-stage biopharmaceutical company developing antibody-drug conjugates (ADCs) against novel oncology targets. Co-founded by Renata Pasqualini, Ph.D. and Isan Chen, MD, the company builds its pipeline on SPARTA, an in vivo antibody selection and target discovery process it uses to find ADC targets that conventional in vitro discovery misses. Its lead candidate MBRC-101 is an anti-EphA5 monomethyl auristatin E (MMAE) antibody-drug conjugate in a multi-centre, open-label Phase 1/1b dose-finding, safety and pharmacokinetic study in advanced refractory solid tumours; MBRC-201 is in Phase 2, MBRC-301 is in IND-enabling studies against solid tumours, and MBRC-401 is in discovery. MBrace emerged from stealth in November 2023 with an $85 million Series B led by TPG through TPG Life Sciences Innovations, alongside Avidity Partners, Blue Owl Capital, Venrock and Alta Partners, bringing total capital raised to $110 million. MBRC-101 was named Most Promising Clinical Candidate at the 11th Annual World ADC Awards. MBrace Therapeutics runs no developer program and publishes no product API, developer portal, API reference or SDK. The only machine-readable surface reachable without credentials is the WordPress REST content API behind mbracetrx.com, catalogued here — notable because the company registered five of its own custom post types, so its board, executive committee, founders, named investors and scientific advisory board are all published as structured JSON rather than only as rendered HTML.

MBrace Therapeutics publishes 1 API contract indexed on the APIs.io network. Tagged areas include Company, Biotechnology, Pharmaceuticals, Oncology, and Antibody-Drug Conjugates.

MBrace Therapeutics’ developer surface includes product news, authentication, and 26 more developer resources.

🌐 Visit website 📡 Source on GitHub

16.8/100 emerging ▬ flat Agent 10/100 agent aware Front door AI 1/6 silent saas Full breakdown ↓
scored 2026-10-09 · rubric v0.23.0

9 published contracts

Company Biotechnology Pharmaceuticals Oncology Antibody-Drug Conjugates Drug Discovery Clinical Trials Life Sciences Precision Medicine content-api

Kin Score

Kin Score How this is scored →
scored 2026-10-09 · rubric v0.23.0

Composite quality — 16.8/100 · emerging

Contract Quality 0.0 / 21

Developer Ergonomics 3.9 / 17

Access Clarity 3.6 / 17

Operational Transparency 0.0 / 11

Contract Governance 0.5 / 10

Discoverability 5.4 / 9

Regulatory Posture 2.9 / 15

Agent readiness — 10/100 · agent aware

Machine-Readable Contract 0 / 18

Agentic Access Contract 0 / 10

Documented Reversibility 6 / 6

MCP Server 0 / 12

Machine-Readable Auth 10 / 10

Idempotency 9 / 9

Stable Error Semantics 8 / 8

Request/Response Examples 0 / 7

Rate-Limit Signaling 7 / 7

Typed Event Surface 0 / 6

Agent Skills 5 / 5

Well-Known Catalog 0 / 4

Consent & Bot Identity 0 / 3

A2A Agent Card 0 / 8

Dry-Run / Simulate Mode 4 / 4

Delegated User Identity 0 / 6

Protected Resource Metadata 0 / 5

Registration Without a Human 0 / 6

Agentic Commerce Well-Known Document 0 / 5

Regulatory Posture applies to this provider. Its tags matched the Health regime, so Regulatory Posture carries 15 points of the composite. If this regime is wrong for your business, say so on your provider repo — the applicability map is public and we will correct it.

Create-or-Update Ergonomics does not apply to this provider. The published contracts declare no write operations, and a read-only API cannot create-or-update. The facet is excluded from this provider's denominator entirely — not scored zero. A reference or data API is not deficient for being unable to upsert.

The six quality facets above are damped to 85 points between them, because the conditional facet above carries the other 15. That is why each facet's contribution is shown against a damped maximum: raising a quality facet moves the composite by 85% of its nominal weight, not 100%. The full arithmetic is at apis.io/rating/.

Improve this rating by publishing the missing artifacts — every area above can be raised, and the full rubric is at apis.io/rating/. Every facet and dimension name above is a link: it opens that measurement's own page — what it means, the exact checks that feed it, how the whole catalog distributes on it, and the providers at the top of it. This rating is computed from github.com/api-evangelist/mbrace-therapeutics: open an issue to ask a question, or submit a pull request to add artifacts. Submit an artifact on GitHub — free → Manage your own listing — the Influence plan, $499/mo →

APIs 1

Individual APIs this provider publishes, each with its own machine-readable definition.

MBrace Therapeutics Website (WordPress REST)

The public WordPress REST API (wp-json) of the MBrace Therapeutics website at mbracetrx.com: the route index of the site's content management system, catalogued as one site surf...

Pricing Plans 1

Published pricing tiers and plan structures.

Mbrace Therapeutics Plans Pricing

0 plans

PLANS

Rate Limits 1

Documented rate limits and quota policies.

Mbrace Therapeutics Rate Limits

0 limits

RATE LIMITS

OpenAPI Overlays 2

Overlays applied on top of this provider's contracts. Each card says who wrote it: a document the provider publishes, or one API Evangelist derived or generated.

Mbrace Therapeutics News Overlay

5 actions · update · mbrace-therapeutics-news-openapi.yml

GENERATED

Mbrace Therapeutics People Overlay

8 actions · update · mbrace-therapeutics-people-openapi.yml

GENERATED

Security Posture 2

Authentication, domain security, vulnerability disclosure, and trust-center signals.

Mbrace Therapeutics Authentication

2 schemes

SECURITY

Mbrace Therapeutics Domain Security

TLSv1.3 · DMARC

SECURITY

Resources

Agent Surfaces 2

MCP servers, agent skills, and machine-readable catalogs

LLMsTxt

LLMsTxt

AgentSkill

AgentSkill

Design & Contract 5

Pagination, idempotency, versioning, errors, and events

Conventions

Conformance

ErrorCatalog

Lifecycle

DataModel

Build 3

SDKs, sample code, and the tooling you integrate with

ClinicalProgram

ClinicalProgram

ClinicalProgram

ClinicalProgram

Packages

Packages

Access & Security 2

Authentication, authorization, and security posture

Authentication

Authentication

DomainSecurity

DomainSecurity

Operate 2

Status, limits, changes, and where to get help

Contact

Contact

RateLimits

RateLimits

Commercial 3

Pricing, plans, and the legal terms of use

PrivacyPolicy

PrivacyPolicy

TermsOfService

TermsOfService

Plans

Plans

Company 5

The organization behind the API

Website

About

News

BlogRSS

LinkedIn

Other 6

Properties that don't map to a standard resource type

Overlay

Overlay

Overlay

Overlay

Pipeline

Pipeline

DiscoveryPlatform

DiscoveryPlatform

ExpandedAccess

ExpandedAccess

SecondaryMarket

SecondaryMarket

Source (apis.yml)

aid: mbrace-therapeutics
name: MBrace Therapeutics
description: MBrace Therapeutics is a privately held, clinical-stage biopharmaceutical company developing antibody-drug conjugates
  (ADCs) against novel oncology targets. Co-founded by Renata Pasqualini, Ph.D. and Isan Chen, MD, the company builds its
  pipeline on SPARTA, an in vivo antibody selection and target discovery process it uses to find ADC targets that conventional
  in vitro discovery misses. Its lead candidate MBRC-101 is an anti-EphA5 monomethyl auristatin E (MMAE) antibody-drug conjugate
  in a multi-centre, open-label Phase 1/1b dose-finding, safety and pharmacokinetic study in advanced refractory solid tumours;
  MBRC-201 is in Phase 2, MBRC-301 is in IND-enabling studies against solid tumours, and MBRC-401 is in discovery. MBrace
  emerged from stealth in November 2023 with an $85 million Series B led by TPG through TPG Life Sciences Innovations, alongside
  Avidity Partners, Blue Owl Capital, Venrock and Alta Partners, bringing total capital raised to $110 million. MBRC-101 was
  named Most Promising Clinical Candidate at the 11th Annual World ADC Awards. MBrace Therapeutics runs no developer program
  and publishes no product API, developer portal, API reference or SDK. The only machine-readable surface reachable without
  credentials is the WordPress REST content API behind mbracetrx.com, catalogued here — notable because the company registered
  five of its own custom post types, so its board, executive committee, founders, named investors and scientific advisory
  board are all published as structured JSON rather than only as rendered HTML.
deliveryModel:
  model: saas
  open_source: false
  commercial: true
  callable_host: true
  label: Hosted service · you call their endpoint
  confidence: high
  source:
  - openapi
  - pricing
  generated: '2026-08-28'
  method: derived
accessModel:
  pricing: unknown
  onboarding: unknown
  trial: false
  try_now: false
  public: false
  label: Unknown
  confidence: low
  source:
  - authentication
  - rate-limits
  - security
  generated: '2026-09-03'
  method: derived
image: https://mbracetrx.com/wp-content/uploads/2021/12/logo-mbrace.svg
url: https://raw.githubusercontent.com/api-evangelist/mbrace-therapeutics/refs/heads/main/apis.yml
x-type: company
x-source: harvest:secondary-market
x-tier: profiled
x-tier-reason: enriched
specificationVersion: '0.23'
created: '2026-08-25'
modified: '2026-08-25'
tags:
- Company
- Biotechnology
- Pharmaceuticals
- Oncology
- Antibody-Drug Conjugates
- Drug Discovery
- Clinical Trials
- Life Sciences
- Precision Medicine
- content-api
tags_raw:
- Company
- biotechnology
- pharmaceuticals
- oncology
- antibody-drug-conjugates
- drug-discovery
- clinical-trials
- life-sciences
- precision-medicine
- content-api
apis:
- aid: mbrace-therapeutics:mbracetrx-com-website-wordpress-rest
  name: MBrace Therapeutics Website (WordPress REST)
  description: 'The public WordPress REST API (wp-json) of the MBrace Therapeutics website at mbracetrx.com: the route index
    of the site''s content management system, catalogued as one site surface rather than as separate APIs.'
  baseURL: https://mbracetrx.com/wp-json
  tags:
  - WordPress
  x-surface: platform-generated
  x-platform: wordpress
  x-platform-surface: rest
  properties:
  - type: Documentation
    url: https://mbracetrx.com/wp-json
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: Overlay
  url: overlays/mbrace-therapeutics-news-overlay.yaml
- type: Overlay
  url: overlays/mbrace-therapeutics-people-overlay.yaml
- type: Website
  url: https://mbracetrx.com/
- type: About
  url: https://mbracetrx.com/about-us/
- type: Pipeline
  url: https://mbracetrx.com/pipeline/
- type: DiscoveryPlatform
  url: https://mbracetrx.com/discovery-platform/
- type: ClinicalProgram
  url: https://mbracetrx.com/clinical-program-mbrc-101/
- type: ClinicalProgram
  url: https://mbracetrx.com/clinical-program-mbrc-201/
- type: ExpandedAccess
  url: https://mbracetrx.com/expanded-access-statement/
- type: News
  url: https://mbracetrx.com/news/
- type: BlogRSS
  url: https://mbracetrx.com/feed/
- type: Contact
  url: https://mbracetrx.com/contact/
- type: PrivacyPolicy
  url: https://mbracetrx.com/privacy-policy/
- type: TermsOfService
  url: https://mbracetrx.com/terms-of-use/
- type: LinkedIn
  url: https://www.linkedin.com/company/mbrace-therapeutics
- type: SecondaryMarket
  url: https://forgeglobal.com/mbrace-therapeutics_stock/
- type: Authentication
  url: authentication/mbrace-therapeutics-authentication.yml
- type: Conventions
  url: conventions/mbrace-therapeutics-conventions.yml
- type: Conformance
  url: conformance/mbrace-therapeutics-conformance.yml
- type: ErrorCatalog
  url: errors/mbrace-therapeutics-problem-types.yml
- type: Lifecycle
  url: lifecycle/mbrace-therapeutics-lifecycle.yml
- type: DataModel
  url: data-model/mbrace-therapeutics-data-model.yml
- type: DomainSecurity
  url: security/mbrace-therapeutics-domain-security.yml
- type: Packages
  url: packages/mbrace-therapeutics-packages.yml
- type: Plans
  url: plans/mbrace-therapeutics-plans-pricing.yml
- type: RateLimits
  url: rate-limits/mbrace-therapeutics-rate-limits.yml
- type: LLMsTxt
  url: llms/mbrace-therapeutics-llms.txt
- type: AgentSkill
  url: skills/_index.yml
x-enrichment:
  date: '2026-08-25'
  status: enriched
  artifacts_added: 28
  pass: local-v1

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