Matterworks website screenshot

Matterworks

Matterworks is a Boston-based life-sciences AI company building foundation models for biochemical omics. Its Large Spectral Model is trained on billions of small-molecule, lipid, peptide, and protein mass-spectrometry spectra across millions of biological contexts, and its Pyxis platform turns raw omics data into quantitative, untargeted biochemical annotations and predictions used for asset and target discovery, mode-of-action elucidation, and life-science R&D pipeline decisions. Matterworks positions biochemical omics as explaining orders of magnitude more biological variation than sequence data alone. The product is accessed through the Pyxis web application (app.matterworks.ai, Auth0 sign-in); no public developer API, OpenAPI, SDK, or documentation surface is published at this time.

Matterworks is profiled on the APIs.io network. Tagged areas include Company, Artificial Intelligence, Metabolomics, Omics, and Life Sciences.

Matterworks’ developer surface includes engineering blog, signup flow, support, and 7 more developer resources.

🌐 Visit website 📡 Source on GitHub
17.8/100 emerging ▬ flat Agent 4/100 human only Full breakdown ↓
scored 2026-07-27 · rubric v0.5
0 APIs
CompanyArtificial IntelligenceMetabolomicsOmicsLife SciencesBiotechnologyMass SpectrometryFoundation Models

Kin Score

Kin Score Kin Score How this is scored →
scored 2026-07-27 · rubric v0.5
Composite quality — 17.8/100 · emerging
Contract Quality 0.0 / 25
Developer Ergonomics 1.3 / 20
Commercial Clarity 6.8 / 20
Operational Transparency 0.7 / 13
Governance 0.0 / 12
Discoverability 6.8 / 10
Agent readiness — 4/100 · human only
Machine-Readable Contract 0 / 18
Agentic Access Contract 0 / 15
MCP Server 0 / 12
Machine-Readable Auth 0 / 10
Idempotency 0 / 9
Stable Error Semantics 0 / 8
Request/Response Examples 0 / 7
Rate-Limit Signaling 0 / 7
Typed Event Surface 0 / 6
Agent Skills 0 / 5
Well-Known Catalog 4 / 4
Consent & Bot Identity 0 / 3
Improve this rating by publishing the missing artifacts — every area above can be raised, and the full rubric is at apis.io/rating/. This rating is computed from github.com/api-evangelist/matterworks: open an issue to ask a question, or submit a pull request to add artifacts. Want it done for you? Prioritized profiling — $2,500 →

Security Posture 1

Authentication, domain security, vulnerability disclosure, and trust-center signals.

Matterworks Domain Security

TLSv1.3 · HSTS

SECURITY

Resources

Get Started 1

Portal, sign-up, and the first successful call

SignUp
SignUp

Agent Surfaces 1

MCP servers, agent skills, and machine-readable catalogs

WellKnown
WellKnown

Build 1

SDKs, sample code, and the tooling you integrate with

GitHubOrganization
GitHubOrganization

Access & Security 1

Authentication, authorization, and security posture

DomainSecurity
DomainSecurity

Operate 1

Status, limits, changes, and where to get help

Support
Support

Commercial 2

Pricing, plans, and the legal terms of use

PrivacyPolicy
PrivacyPolicy
 TermsOfService
TermsOfService

Company 2

The organization behind the API

Website
Website
 Blog
Blog

Other 1

Properties that don't map to a standard resource type

Platform
Platform

Source (apis.yml)

apis.yml Raw ↑ 
aid: matterworks
name: Matterworks
description: Matterworks is a Boston-based life-sciences AI company building foundation models for biochemical omics. Its
  Large Spectral Model is trained on billions of small-molecule, lipid, peptide, and protein mass-spectrometry spectra across
  millions of biological contexts, and its Pyxis platform turns raw omics data into quantitative, untargeted biochemical annotations
  and predictions used for asset and target discovery, mode-of-action elucidation, and life-science R&D pipeline decisions.
  Matterworks positions biochemical omics as explaining orders of magnitude more biological variation than sequence data alone.
  The product is accessed through the Pyxis web application (app.matterworks.ai, Auth0 sign-in); no public developer API,
  OpenAPI, SDK, or documentation surface is published at this time.
url: https://raw.githubusercontent.com/api-evangelist/matterworks/refs/heads/main/apis.yml
accessModel:
  pricing: unknown
  onboarding: unknown
  trial: false
  try_now: false
  public: false
  label: Unknown
  confidence: low
  source: []
  generated: '2026-07-22'
  method: derived
image: https://avatars.githubusercontent.com/u/66066030?v=4
x-type: company
x-source: vc-portfolio
x-backed-by:
- wing-venture-capital
x-tier: stub
x-tier-reason: portfolio-lead
specificationVersion: '0.20'
created: '2026-07-17'
modified: '2026-07-20'
tags:
- Company
- Artificial Intelligence
- Metabolomics
- Omics
- Life Sciences
- Biotechnology
- Mass Spectrometry
- Foundation Models
apis: []
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: DomainSecurity
  url: security/matterworks-domain-security.yml
- type: WellKnown
  url: well-known/matterworks-well-known.yml
- type: Website
  url: https://www.matterworks.ai/
- type: Platform
  url: https://www.matterworks.ai/platform
- type: Blog
  url: https://www.matterworks.ai/insights
- type: GitHubOrganization
  url: https://github.com/matterworksbio
- type: SignUp
  url: https://app.matterworks.ai/sign-up
- type: Support
  url: https://www.matterworks.ai/#contact-us
- type: PrivacyPolicy
  url: https://www.matterworks.ai/privacy-policy
- type: TermsOfService
  url: https://www.matterworks.ai/terms-of-use
x-enrichment:
  date: '2026-07-20'
  status: enriched
  artifacts_added: 3
  pass: local-v1