Manifold Bio website screenshot

Manifold Bio

Manifold Bio is a biotechnology company developing tissue-targeted biologic medicines. It runs a high-throughput in vivo discovery engine that pairs massively multiplexed in vivo screening — using mCode protein barcodes read out by DNA sequencing — with AI-powered protein and antibody design (mBER) and engineered mShuttle delivery vehicles. Its pipeline targets CNS diseases such as Alzheimer's and Parkinson's (amyloid-beta, tau, alpha-synuclein) and peripheral cardiometabolic disease. Backed by Playground Global. The company publishes no public developer API, SDK, documentation, or event surface as of this enrichment pass.

Manifold Bio is profiled on the APIs.io network. Tagged areas include Company, Engineered Biology, Biotechnology, Drug Discovery, and Protein Design.

6.8/100 minimal ▬ flat Agent 0/100 human only Full breakdown ↓
scored 2026-07-27 · rubric v0.5
0 APIs
CompanyEngineered BiologyBiotechnologyDrug DiscoveryProtein DesignTherapeuticsAntibody EngineeringArtificial Intelligence

Kin Score

Kin Score Kin Score How this is scored →
scored 2026-07-27 · rubric v0.5
Composite quality — 6.8/100 · minimal
Contract Quality 0.0 / 25
Developer Ergonomics 0.0 / 20
Commercial Clarity 0.0 / 20
Operational Transparency 0.0 / 13
Governance 0.0 / 12
Discoverability 6.8 / 10
Agent readiness — 0/100 · human only
Machine-Readable Contract 0 / 18
Agentic Access Contract 0 / 15
MCP Server 0 / 12
Machine-Readable Auth 0 / 10
Idempotency 0 / 9
Stable Error Semantics 0 / 8
Request/Response Examples 0 / 7
Rate-Limit Signaling 0 / 7
Typed Event Surface 0 / 6
Agent Skills 0 / 5
Well-Known Catalog 0 / 4
Consent & Bot Identity 0 / 3
Improve this rating by publishing the missing artifacts — every area above can be raised, and the full rubric is at apis.io/rating/. This rating is computed from github.com/api-evangelist/manifold-bio: open an issue to ask a question, or submit a pull request to add artifacts. Want it done for you? Prioritized profiling — $2,500 →

Security Posture 1

Authentication, domain security, vulnerability disclosure, and trust-center signals.

Manifold Bio Domain Security

TLSv1.3 · HSTS

SECURITY

Resources

Access & Security 1

Authentication, authorization, and security posture

Company 1

The organization behind the API

Source (apis.yml)

apis.yml Raw ↑
aid: manifold-bio
accessModel:
  pricing: unknown
  onboarding: unknown
  trial: false
  try_now: false
  public: false
  label: Unknown
  confidence: low
  source: []
  generated: '2026-07-22'
  method: derived
image: https://kinlane-images.s3.amazonaws.com/shared/apis-json/icons/manifold-bio.png
name: Manifold Bio
description: Manifold Bio is a biotechnology company developing tissue-targeted biologic medicines. It runs a high-throughput
  in vivo discovery engine that pairs massively multiplexed in vivo screening — using mCode protein barcodes read out by DNA
  sequencing — with AI-powered protein and antibody design (mBER) and engineered mShuttle delivery vehicles. Its pipeline
  targets CNS diseases such as Alzheimer's and Parkinson's (amyloid-beta, tau, alpha-synuclein) and peripheral cardiometabolic
  disease. Backed by Playground Global. The company publishes no public developer API, SDK, documentation, or event surface
  as of this enrichment pass.
url: https://raw.githubusercontent.com/api-evangelist/manifold-bio/refs/heads/main/apis.yml
x-type: company
x-source: vc-portfolio
x-backed-by:
- playground-global
x-tier: stub
x-tier-reason: portfolio-lead
specificationVersion: '0.20'
created: '2026-07-17'
modified: '2026-07-20'
tags:
- Company
- Engineered Biology
- Biotechnology
- Drug Discovery
- Protein Design
- Therapeutics
- Antibody Engineering
- Artificial Intelligence
apis: []
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
x-enrichment:
  date: '2026-07-20'
  status: minimal
  artifacts_added: 1
  pass: local-v1
common:
- type: DomainSecurity
  url: security/manifold-bio-domain-security.yml
- type: Website
  url: https://www.manifold.bio/