LEAF4Life Inc. is a privately held, clinical-stage biopharmaceutical company headquartered in Woburn, Massachusetts, founded in 2018 by Dr. Clet Niyikiza to develop transformative therapies for hypoxia — insufficient oxygen at the tissue and cellular level — which the company describes as implicated in the world's ten leading causes of death and more than 30 million deaths a year. Its lead asset, KizaVie™ (LEAF-4L6715), is a proprietary liposomal formulation of transcrocetin, a naturally occurring carotenoid from saffron and cape jasmine, designed to enhance oxygen diffusion in plasma and interstitium, restore microcirculatory oxygen delivery and repair hypoxia-driven microvascular and tissue damage, thereby improving the effectiveness of standard-of-care treatment. KizaVie™ is in three Phase 3 registrational studies in Europe — acute respiratory distress syndrome (ARDS), glioblastoma and sarcoma — and has received Compassionate Use Authorization in France for ARDS. The company also describes application to shock and trauma, cardiovascular disease, neurodegenerative disorders and aging. LEAF4Life runs no developer program and publishes no product API, developer portal, API reference, SDK or OpenAPI definition. The only machine-readable surface reachable without credentials is the WordPress REST content API behind leafforlife.com, catalogued here, and even that returns page identity and media only — every page body is empty over the API because the site is assembled by a page builder.
LEAF4Life publishes 9 APIs on the APIs.io network, including Content Pages API, Media API, Taxonomy API, and 6 more. Tagged areas include Company, Biotechnology, Pharmaceuticals, Clinical Trials, and Oncology.
LEAF4Life’s developer surface includes authentication and 18 more developer resources.
Regulatory Posture applies to this provider. Its tags matched the
Health regime, so
Regulatory Posture carries 15 points of the composite.
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The six quality facets above are damped to 85 points between them,
because the conditional facet above carries the other
15. That is why each facet's contribution is shown against a damped
maximum: raising a quality facet moves the composite by 85% of its nominal
weight, not 100%. The full arithmetic is at apis.io/rating/.
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The page collection behind leafforlife.com — 8 published pages covering the mission, the science, leadership, the advisory board and contact. Anonymously readable. Verified 2026...
The WordPress media library behind leafforlife.com — 59 image attachments (43 PNG, 16 JPEG) spanning September 2020 to July 2026, including the brand marks, leadership headshots...
Category and tag terms. Registered and anonymously reachable but effectively unused — one category (the WordPress default `uncategorized`) and 21 tags, every one with an item co...
The self-describing routes of the deployment — registered post types, taxonomies and post statuses, plus the route index at the server root that publishes name, description, nam...
Cross-type site search returning lightweight result stubs. Live and correct, but it returns zero for every site term tried — including with subtype=page — because WordPress inde...
Published authors. One entry — a shared editorial account, `leaf4l` — exposing only id, name, slug, link, description and avatar URLs anonymously. No personal names, e-mail addr...
Post and comment collections. Registered and anonymously reachable, both empty — LEAF4Life publishes no news archive, press-release feed or blog through WordPress, so the /feed/...
oEmbed 1.0 provider endpoint for URLs on leafforlife.com. Verified anonymously against the site root — provider_name "LEAF4life". This is the only formally standardised interfac...
aid: leaf4life
name: LEAF4Life
description: LEAF4Life Inc. is a privately held, clinical-stage biopharmaceutical company headquartered in Woburn, Massachusetts,
founded in 2018 by Dr. Clet Niyikiza to develop transformative therapies for hypoxia — insufficient oxygen at the tissue
and cellular level — which the company describes as implicated in the world's ten leading causes of death and more than
30 million deaths a year. Its lead asset, KizaVie™ (LEAF-4L6715), is a proprietary liposomal formulation of transcrocetin,
a naturally occurring carotenoid from saffron and cape jasmine, designed to enhance oxygen diffusion in plasma and interstitium,
restore microcirculatory oxygen delivery and repair hypoxia-driven microvascular and tissue damage, thereby improving the
effectiveness of standard-of-care treatment. KizaVie™ is in three Phase 3 registrational studies in Europe — acute respiratory
distress syndrome (ARDS), glioblastoma and sarcoma — and has received Compassionate Use Authorization in France for ARDS.
The company also describes application to shock and trauma, cardiovascular disease, neurodegenerative disorders and aging.
LEAF4Life runs no developer program and publishes no product API, developer portal, API reference, SDK or OpenAPI definition.
The only machine-readable surface reachable without credentials is the WordPress REST content API behind leafforlife.com,
catalogued here, and even that returns page identity and media only — every page body is empty over the API because the
site is assembled by a page builder.
deliveryModel:
model: saas
open_source: false
commercial: true
callable_host: true
label: Hosted service · you call their endpoint
confidence: high
source:
- openapi
- pricing
generated: '2026-08-28'
method: derived
accessModel:
pricing: unknown
onboarding: self-serve
trial: false
try_now: false
public: false
label: Self-serve signup
confidence: medium
source:
- authentication
- rate-limits
- security
generated: '2026-09-02'
method: derived
image: https://leafforlife.com/wp-content/uploads/2025/11/LEAF4Life_logo_cropped_final.png
url: https://raw.githubusercontent.com/api-evangelist/leaf4life/refs/heads/main/apis.yml
x-type: company
x-source: harvest:secondary-market
x-tier: profiled
x-tier-reason: enriched
specificationVersion: '0.23'
created: '2026-08-25'
modified: '2026-08-25'
tags:
- Company
- Biotechnology
- Pharmaceuticals
- Clinical Trials
- Oncology
- Critical Care
- Drug Development
- Life Sciences
- Rare Disease
- content-api
tags_raw:
- Company
- biotechnology
- pharmaceuticals
- clinical-trials
- oncology
- critical-care
- drug-development
- life-sciences
- rare-disease
- content-api
apis:
- aid: leaf4life:leaf4life-pages-api
name: LEAF4Life Content Pages API
description: 'The page collection behind leafforlife.com — 8 published pages covering the mission, the science, leadership,
the advisory board and contact. Anonymously readable. Verified 2026-08-25: content.rendered is empty on every page because
the theme assembles bodies with a page builder, so the route yields page identity, links and dates but no page text.'
humanURL: https://developer.wordpress.org/rest-api/
baseURL: https://leafforlife.com/wp-json
tags:
- Pages
- Content
tags_raw:
- pages
- content
properties:
- type: OpenAPI
url: openapi/leaf4life-pages-api-openapi.yml
- type: Authentication
url: authentication/leaf4life-authentication.yml
- type: ErrorCatalog
url: errors/leaf4life-problem-types.yml
- type: Conventions
url: conventions/leaf4life-conventions.yml
- type: DataModel
url: data-model/leaf4life-data-model.yml
- aid: leaf4life:leaf4life-media-api
name: LEAF4Life Media API
description: The WordPress media library behind leafforlife.com — 59 image attachments (43 PNG, 16 JPEG) spanning September
2020 to July 2026, including the brand marks, leadership headshots and the figure artwork used on the science pages. Anonymously
readable. No PDFs, documents or datasets are published.
humanURL: https://developer.wordpress.org/rest-api/
baseURL: https://leafforlife.com/wp-json
tags:
- Media
tags_raw:
- media
properties:
- type: OpenAPI
url: openapi/leaf4life-media-api-openapi.yml
- type: Authentication
url: authentication/leaf4life-authentication.yml
- type: ErrorCatalog
url: errors/leaf4life-problem-types.yml
- type: Conventions
url: conventions/leaf4life-conventions.yml
- type: DataModel
url: data-model/leaf4life-data-model.yml
- aid: leaf4life:leaf4life-taxonomy-api
name: LEAF4Life Taxonomy API
description: Category and tag terms. Registered and anonymously reachable but effectively unused — one category (the WordPress
default `uncategorized`) and 21 tags, every one with an item count of zero, and the tag slugs are theme-demo residue rather
than company vocabulary.
humanURL: https://developer.wordpress.org/rest-api/
baseURL: https://leafforlife.com/wp-json
tags:
- Taxonomy
tags_raw:
- taxonomy
properties:
- type: OpenAPI
url: openapi/leaf4life-taxonomy-api-openapi.yml
- type: Authentication
url: authentication/leaf4life-authentication.yml
- type: ErrorCatalog
url: errors/leaf4life-problem-types.yml
- type: Conventions
url: conventions/leaf4life-conventions.yml
- type: DataModel
url: data-model/leaf4life-data-model.yml
- aid: leaf4life:leaf4life-discovery-api
name: LEAF4Life API Discovery
description: The self-describing routes of the deployment — registered post types, taxonomies and post statuses, plus the
route index at the server root that publishes name, description, namespaces, all 150 routes and the application-passwords
authentication block.
humanURL: https://developer.wordpress.org/rest-api/
baseURL: https://leafforlife.com/wp-json
tags:
- Discovery
- Schema
tags_raw:
- discovery
- schema
properties:
- type: OpenAPI
url: openapi/leaf4life-discovery-api-openapi.yml
- type: Authentication
url: authentication/leaf4life-authentication.yml
- type: ErrorCatalog
url: errors/leaf4life-problem-types.yml
- type: Conventions
url: conventions/leaf4life-conventions.yml
- type: DataModel
url: data-model/leaf4life-data-model.yml
- aid: leaf4life:leaf4life-search-api
name: LEAF4Life Search API
description: Cross-type site search returning lightweight result stubs. Live and correct, but it returns zero for every
site term tried — including with subtype=page — because WordPress indexes post_content and this deployment's page bodies
live in page-builder postmeta instead.
humanURL: https://developer.wordpress.org/rest-api/
baseURL: https://leafforlife.com/wp-json
tags:
- Search
tags_raw:
- search
properties:
- type: OpenAPI
url: openapi/leaf4life-search-api-openapi.yml
- type: Authentication
url: authentication/leaf4life-authentication.yml
- type: ErrorCatalog
url: errors/leaf4life-problem-types.yml
- type: Conventions
url: conventions/leaf4life-conventions.yml
- type: DataModel
url: data-model/leaf4life-data-model.yml
- aid: leaf4life:leaf4life-users-api
name: LEAF4Life Authors API
description: Published authors. One entry — a shared editorial account, `leaf4l` — exposing only id, name, slug, link, description
and avatar URLs anonymously. No personal names, e-mail addresses or roles are disclosed.
humanURL: https://developer.wordpress.org/rest-api/
baseURL: https://leafforlife.com/wp-json
tags:
- User
tags_raw:
- users
properties:
- type: OpenAPI
url: openapi/leaf4life-users-api-openapi.yml
- type: Authentication
url: authentication/leaf4life-authentication.yml
- type: ErrorCatalog
url: errors/leaf4life-problem-types.yml
- type: Conventions
url: conventions/leaf4life-conventions.yml
- type: DataModel
url: data-model/leaf4life-data-model.yml
- aid: leaf4life:leaf4life-posts-api
name: LEAF4Life Posts and Comments API
description: Post and comment collections. Registered and anonymously reachable, both empty — LEAF4Life publishes no news
archive, press-release feed or blog through WordPress, so the /feed/ RSS endpoint the theme advertises is also empty.
Catalogued because a measured absence against a live route is data.
humanURL: https://developer.wordpress.org/rest-api/
baseURL: https://leafforlife.com/wp-json
tags:
- Posts
- Comments
tags_raw:
- posts
- comments
properties:
- type: OpenAPI
url: openapi/leaf4life-posts-api-openapi.yml
- type: Authentication
url: authentication/leaf4life-authentication.yml
- type: ErrorCatalog
url: errors/leaf4life-problem-types.yml
- type: Conventions
url: conventions/leaf4life-conventions.yml
- type: DataModel
url: data-model/leaf4life-data-model.yml
- aid: leaf4life:leaf4life-oembed-api
name: LEAF4Life oEmbed API
description: oEmbed 1.0 provider endpoint for URLs on leafforlife.com. Verified anonymously against the site root — provider_name
"LEAF4life". This is the only formally standardised interface the deployment implements.
humanURL: https://oembed.com/
baseURL: https://leafforlife.com/wp-json
tags:
- oEmbed
- Embeds
tags_raw:
- oembed
- embeds
properties:
- type: OpenAPI
url: openapi/leaf4life-oembed-api-openapi.yml
- type: Authentication
url: authentication/leaf4life-authentication.yml
- type: ErrorCatalog
url: errors/leaf4life-problem-types.yml
- type: Conventions
url: conventions/leaf4life-conventions.yml
- type: Conformance
url: conformance/leaf4life-conformance.yml
- aid: leaf4life:leaf4life-comments-api
name: LEAF4Life Comments API
description: Comment collection — registered, zero items.
humanURL: https://developer.wordpress.org/rest-api/
baseURL: https://leafforlife.com/wp-json
tags:
- Comments
tags_raw:
- comments
properties:
- type: OpenAPI
url: openapi/leaf4life-comments-api-openapi.yml
maintainers:
- FN: Kin Lane
email: kin@apievangelist.com
- FN: APIs.json
email: info@apis.io
common:
- type: Website
url: https://leafforlife.com/
- type: About
url: https://leafforlife.com/our-science/
- type: Leadership
url: https://leafforlife.com/management-team/
- type: AdvisoryBoard
url: https://leafforlife.com/advisory-board/
- type: Contact
url: https://leafforlife.com/contact-us/
- type: LinkedIn
url: https://www.linkedin.com/company/leaf4life-inc
- type: SecondaryMarket
url: https://equityzen.com/company/leaf4life/
- type: Overlay
url: overlays/leaf4life-content-overlay.yaml
- type: Authentication
url: authentication/leaf4life-authentication.yml
- type: Conventions
url: conventions/leaf4life-conventions.yml
- type: Conformance
url: conformance/leaf4life-conformance.yml
- type: ErrorCatalog
url: errors/leaf4life-problem-types.yml
- type: Lifecycle
url: lifecycle/leaf4life-lifecycle.yml
- type: DataModel
url: data-model/leaf4life-data-model.yml
- type: DomainSecurity
url: security/leaf4life-domain-security.yml
- type: RateLimits
url: rate-limits/leaf4life-rate-limits.yml
- type: Plans
url: plans/leaf4life-plans-pricing.yml
- type: LLMsTxt
url: llms/leaf4life-llms.txt
- type: AgentSkill
url: skills/_index.yml
x-enrichment:
date: '2026-08-25'
status: enriched
artifacts_added: 26
pass: local-v1