KSQ Therapeutics

KSQ Therapeutics is a clinical-stage biotechnology company headquartered at 4 Maguire Road in Lexington, Massachusetts, founded in 2015 by pioneers of CRISPR screening and functional genomics. Its proprietary CRISPRomics platform runs genome-scale CRISPR/Cas9 functional genomic screens across cancer models and immune cell types to identify therapeutic targets that directly correlate genomic function to disease. The company applies those targets in two directions: CRISPR/Cas9-engineered tumor-infiltrating lymphocyte (eTIL) cell therapies, where a single gene is inactivated to increase the tumor-killing capacity of a patient's own T cells — KSQ-001EX (SOCS1 inactivated) and KSQ-004EX (SOCS1 and Regnase-1 inactivated) — and small molecules such as KSQ-4279, a first-in-class USP1 inhibitor for advanced solid tumors. KSQ has run broad discovery collaborations with Takeda, licensed cell-therapy technology with CRISPR Therapeutics, partnered manufacturing with CTMC, and sold multiple research-stage oncology programs to Ono Pharmaceutical. Investors include Flagship Pioneering, ARCH Venture Partners, Polaris Partners, Alexandria, Alpha Wave Global, Baillie Gifford, Invus, LG and Lilly Asia Ventures. KSQ Therapeutics runs no developer program and publishes no product API, developer portal, OpenAPI or API reference. The only machine-readable surfaces reachable without credentials are the WordPress REST content API behind ksqtx.com, an All in One SEO generated /llms.txt, and the open-source bioinformatics code in its public GitHub organization — all catalogued here.

KSQ Therapeutics publishes 8 APIs on the APIs.io network, including Press Releases API, Pages API, Media API, and 5 more. Tagged areas include Company, Biotechnology, Life Sciences, Therapeutics, and Oncology.

KSQ Therapeutics’ developer surface includes engineering blog, product news, support, authentication, CLI, and 25 more developer resources.

32.1/100 thin Agent 38/100 agent ready Full breakdown ↓
scored 2026-08-24 · rubric v0.12.1
8 APIs
CompanyBiotechnologyLife SciencesTherapeuticsOncologyGenomicsCRISPRGene EditingCell TherapyClinical StageFunctional Genomicscontent-api

Kin Score

Kin Score Kin Score How this is scored →
scored 2026-08-24 · rubric v0.12.1
Composite quality — 32.1/100 · thin
Contract Quality 10.7 / 21
Developer Ergonomics 5.7 / 17
Access Clarity 0.0 / 17
Operational Transparency 0.6 / 11
Contract Governance 3.1 / 10
Discoverability 6.9 / 9
Regulatory Posture 3.2 / 15
Agent readiness — 38/100 · agent ready
Machine-Readable Contract 18 / 18
Agentic Access Contract 0 / 10
Documented Reversibility 0 / 6
MCP Server 0 / 12
Machine-Readable Auth 10 / 10
Idempotency 0 / 9
Stable Error Semantics 8 / 8
Request/Response Examples 0 / 7
Rate-Limit Signaling 7 / 7
Typed Event Surface 0 / 6
Agent Skills 5 / 5
Well-Known Catalog 0 / 4
Consent & Bot Identity 0 / 3
A2A Agent Card 0 / 8
Dry-Run / Simulate Mode 0 / 4
Regulatory Posture applies to this provider. Its tags matched the Health regime, so Regulatory Posture carries 15 points of the composite. If this regime is wrong for your business, say so on your provider repo — the applicability map is public and we will correct it.
The six quality facets above are damped to 85 points between them, because the conditional facet above carries the other 15. That is why each facet's contribution is shown against a damped maximum: raising a quality facet moves the composite by 85% of its nominal weight, not 100%. The full arithmetic is at apis.io/rating/.
Improve this rating by publishing the missing artifacts — every area above can be raised, and the full rubric is at apis.io/rating/. This rating is computed from github.com/api-evangelist/ksq-therapeutics: open an issue to ask a question, or submit a pull request to add artifacts. Want it done for you? Prioritized profiling — $2,500 →

APIs 8

Individual APIs this provider publishes, each with its own machine-readable definition.

KSQ Therapeutics Press Releases API

The press_release custom post type behind ksqtx.com — the company news archive. 39 items were returned anonymously on 2026-08-23 (X-WP-Total), spanning the Takeda and Ono collab...

KSQ Therapeutics Pages API

WordPress page collection behind ksqtx.com — Home, About, Platform, Pipeline, Partners, News, Press Releases, Careers and the Expanded Access Policy. 9 items on 2026-08-23. Bodi...

KSQ Therapeutics Media API

WordPress media library — 235 attachments on 2026-08-23, including leadership and board headshots, pipeline and platform graphics, poster PDFs and the homepage background video.

KSQ Therapeutics Search API

Cross-type WordPress search over every REST-exposed post type. 48 results anonymously on 2026-08-23. Returns lightweight {id, title, url, type, subtype} records.

KSQ Therapeutics Discovery API

The WordPress REST route index, namespace index, registered post types, taxonomies and statuses. 349 routes across 9 namespaces on 2026-08-23. This is the only machine-readable ...

KSQ Therapeutics Taxonomy API

Category and post_tag term collections. Registered and anonymously reachable; one category term ("Uncategorized", 5 posts) and zero tags on 2026-08-23.

KSQ Therapeutics Posts API

The core WordPress post collection. Registered and anonymously reachable, but empty on this deployment (X-WP-Total 0 on 2026-08-23) — KSQ publishes news through press_release in...

KSQ Therapeutics oEmbed API

oEmbed 1.0 discovery for ksqtx.com URLs. Verified live anonymously on 2026-08-23 — provider_name "KSQ Therapeutics", provider_url https://ksqtx.com.

Scroll for all 8

Pricing Plans 1

Published pricing tiers and plan structures.

Rate Limits 1

Documented rate limits and quota policies.

Ksq Therapeutics Rate Limits

0 limits

RATE LIMITS

Security Posture 2

Authentication, domain security, vulnerability disclosure, and trust-center signals.

Ksq Therapeutics Domain Security

TLSv1.2 · HSTS · DMARC

SECURITY

Resources

Agent Surfaces 2

MCP servers, agent skills, and machine-readable catalogs

Design & Contract 5

Pagination, idempotency, versioning, errors, and events

Build 4

SDKs, sample code, and the tooling you integrate with

Access & Security 2

Authentication, authorization, and security posture

Operate 2

Status, limits, changes, and where to get help

Commercial 1

Pricing, plans, and the legal terms of use

Company 9

The organization behind the API

Scroll for all 9

Other 5

Properties that don't map to a standard resource type

Source (apis.yml)

apis.yml Raw ↑
aid: ksq-therapeutics
name: KSQ Therapeutics
description: 'KSQ Therapeutics is a clinical-stage biotechnology company headquartered at 4 Maguire Road in Lexington, Massachusetts,
  founded in 2015 by pioneers of CRISPR screening and functional genomics. Its proprietary CRISPRomics platform runs genome-scale
  CRISPR/Cas9 functional genomic screens across cancer models and immune cell types to identify therapeutic targets that directly
  correlate genomic function to disease. The company applies those targets in two directions: CRISPR/Cas9-engineered tumor-infiltrating
  lymphocyte (eTIL) cell therapies, where a single gene is inactivated to increase the tumor-killing capacity of a patient''s
  own T cells — KSQ-001EX (SOCS1 inactivated) and KSQ-004EX (SOCS1 and Regnase-1 inactivated) — and small molecules such as
  KSQ-4279, a first-in-class USP1 inhibitor for advanced solid tumors. KSQ has run broad discovery collaborations with Takeda,
  licensed cell-therapy technology with CRISPR Therapeutics, partnered manufacturing with CTMC, and sold multiple research-stage
  oncology programs to Ono Pharmaceutical. Investors include Flagship Pioneering, ARCH Venture Partners, Polaris Partners,
  Alexandria, Alpha Wave Global, Baillie Gifford, Invus, LG and Lilly Asia Ventures. KSQ Therapeutics runs no developer program
  and publishes no product API, developer portal, OpenAPI or API reference. The only machine-readable surfaces reachable without
  credentials are the WordPress REST content API behind ksqtx.com, an All in One SEO generated /llms.txt, and the open-source
  bioinformatics code in its public GitHub organization — all catalogued here.'
url: https://raw.githubusercontent.com/api-evangelist/ksq-therapeutics/refs/heads/main/apis.yml
image: https://ksqtx.com/wp-content/uploads/2024/02/KSQ-logo-color-RegTM.png
x-type: company
x-source: harvest:secondary-market
x-tier: profiled
x-tier-reason: enrichment
specificationVersion: '0.23'
created: '2026-08-23'
modified: '2026-08-23'
tags:
- Company
- Biotechnology
- Life Sciences
- Therapeutics
- Oncology
- Genomics
- CRISPR
- Gene Editing
- Cell Therapy
- Clinical Stage
- Functional Genomics
- content-api
tags_raw:
- Company
- biotechnology
- life-sciences
- therapeutics
- oncology
- genomics
- crispr
- gene-editing
- cell-therapy
- clinical-stage
- functional-genomics
- content-api
apis:
- aid: ksq-therapeutics:ksq-therapeutics-press-releases-api
  name: KSQ Therapeutics Press Releases API
  description: The press_release custom post type behind ksqtx.com — the company news archive. 39 items were returned anonymously
    on 2026-08-23 (X-WP-Total), spanning the Takeda and Ono collaborations, the CRISPR Therapeutics license agreement, the
    KSQ-001EX / KSQ-004EX / KSQ-4279 IND clearances and first-patient-dosed announcements, and conference poster presentations.
    This is content-management platform infrastructure, not a product KSQ markets.
  humanURL: https://developer.wordpress.org/rest-api/
  baseURL: https://ksqtx.com/wp-json
  tags:
  - press_release
  tags_raw:
  - press-releases
  - news
  x-origin: platform-default
  x-origin-note: Provided by WordPress core REST API, not authored or marketed by KSQ Therapeutics.
  properties:
  - type: OpenAPI
    url: openapi/ksq-therapeutics-press-releases-api-openapi.yml
  - type: Authentication
    url: authentication/ksq-therapeutics-authentication.yml
  - type: ErrorCatalog
    url: errors/ksq-therapeutics-problem-types.yml
  - type: Conventions
    url: conventions/ksq-therapeutics-conventions.yml
  - type: DataModel
    url: data-model/ksq-therapeutics-data-model.yml
- aid: ksq-therapeutics:ksq-therapeutics-pages-api
  name: KSQ Therapeutics Pages API
  description: WordPress page collection behind ksqtx.com — Home, About, Platform, Pipeline, Partners, News, Press Releases,
    Careers and the Expanded Access Policy. 9 items on 2026-08-23. Bodies are Divi page-builder markup delivered as rendered
    HTML.
  humanURL: https://developer.wordpress.org/rest-api/
  baseURL: https://ksqtx.com/wp-json
  tags:
  - pages
  tags_raw:
  - pages
  x-origin: platform-default
  properties:
  - type: OpenAPI
    url: openapi/ksq-therapeutics-pages-api-openapi.yml
  - type: Authentication
    url: authentication/ksq-therapeutics-authentication.yml
  - type: ErrorCatalog
    url: errors/ksq-therapeutics-problem-types.yml
  - type: Conventions
    url: conventions/ksq-therapeutics-conventions.yml
  - type: DataModel
    url: data-model/ksq-therapeutics-data-model.yml
- aid: ksq-therapeutics:ksq-therapeutics-media-api
  name: KSQ Therapeutics Media API
  description: WordPress media library — 235 attachments on 2026-08-23, including leadership and board headshots, pipeline
    and platform graphics, poster PDFs and the homepage background video.
  humanURL: https://developer.wordpress.org/rest-api/
  baseURL: https://ksqtx.com/wp-json
  tags:
  - media
  tags_raw:
  - media
  x-origin: platform-default
  properties:
  - type: OpenAPI
    url: openapi/ksq-therapeutics-media-api-openapi.yml
  - type: Authentication
    url: authentication/ksq-therapeutics-authentication.yml
  - type: ErrorCatalog
    url: errors/ksq-therapeutics-problem-types.yml
  - type: Conventions
    url: conventions/ksq-therapeutics-conventions.yml
  - type: DataModel
    url: data-model/ksq-therapeutics-data-model.yml
- aid: ksq-therapeutics:ksq-therapeutics-search-api
  name: KSQ Therapeutics Search API
  description: Cross-type WordPress search over every REST-exposed post type. 48 results anonymously on 2026-08-23. Returns
    lightweight {id, title, url, type, subtype} records.
  humanURL: https://developer.wordpress.org/rest-api/
  baseURL: https://ksqtx.com/wp-json
  tags:
  - search
  tags_raw:
  - search
  x-origin: platform-default
  properties:
  - type: OpenAPI
    url: openapi/ksq-therapeutics-search-api-openapi.yml
  - type: Authentication
    url: authentication/ksq-therapeutics-authentication.yml
  - type: ErrorCatalog
    url: errors/ksq-therapeutics-problem-types.yml
  - type: Conventions
    url: conventions/ksq-therapeutics-conventions.yml
  - type: DataModel
    url: data-model/ksq-therapeutics-data-model.yml
- aid: ksq-therapeutics:ksq-therapeutics-discovery-api
  name: KSQ Therapeutics Discovery API
  description: The WordPress REST route index, namespace index, registered post types, taxonomies and statuses. 349 routes
    across 9 namespaces on 2026-08-23. This is the only machine-readable contract KSQ Therapeutics serves, and the source
    every derived artifact in this repo was built from.
  humanURL: https://developer.wordpress.org/rest-api/
  baseURL: https://ksqtx.com/wp-json
  tags:
  - discovery
  tags_raw:
  - discovery
  x-origin: platform-default
  properties:
  - type: OpenAPI
    url: openapi/ksq-therapeutics-discovery-api-openapi.yml
  - type: Authentication
    url: authentication/ksq-therapeutics-authentication.yml
  - type: ErrorCatalog
    url: errors/ksq-therapeutics-problem-types.yml
  - type: Conventions
    url: conventions/ksq-therapeutics-conventions.yml
  - type: DataModel
    url: data-model/ksq-therapeutics-data-model.yml
- aid: ksq-therapeutics:ksq-therapeutics-taxonomy-api
  name: KSQ Therapeutics Taxonomy API
  description: Category and post_tag term collections. Registered and anonymously reachable; one category term ("Uncategorized",
    5 posts) and zero tags on 2026-08-23.
  humanURL: https://developer.wordpress.org/rest-api/
  baseURL: https://ksqtx.com/wp-json
  tags:
  - taxonomy
  tags_raw:
  - taxonomy
  x-origin: platform-default
  properties:
  - type: OpenAPI
    url: openapi/ksq-therapeutics-taxonomy-api-openapi.yml
  - type: Authentication
    url: authentication/ksq-therapeutics-authentication.yml
  - type: ErrorCatalog
    url: errors/ksq-therapeutics-problem-types.yml
  - type: Conventions
    url: conventions/ksq-therapeutics-conventions.yml
  - type: DataModel
    url: data-model/ksq-therapeutics-data-model.yml
- aid: ksq-therapeutics:ksq-therapeutics-posts-api
  name: KSQ Therapeutics Posts API
  description: The core WordPress post collection. Registered and anonymously reachable, but empty on this deployment (X-WP-Total
    0 on 2026-08-23) — KSQ publishes news through press_release instead.
  humanURL: https://developer.wordpress.org/rest-api/
  baseURL: https://ksqtx.com/wp-json
  tags:
  - posts
  tags_raw:
  - posts
  x-origin: platform-default
  properties:
  - type: OpenAPI
    url: openapi/ksq-therapeutics-posts-api-openapi.yml
  - type: Authentication
    url: authentication/ksq-therapeutics-authentication.yml
  - type: ErrorCatalog
    url: errors/ksq-therapeutics-problem-types.yml
  - type: Conventions
    url: conventions/ksq-therapeutics-conventions.yml
  - type: DataModel
    url: data-model/ksq-therapeutics-data-model.yml
- aid: ksq-therapeutics:ksq-therapeutics-oembed-api
  name: KSQ Therapeutics oEmbed API
  description: oEmbed 1.0 discovery for ksqtx.com URLs. Verified live anonymously on 2026-08-23 — provider_name "KSQ Therapeutics",
    provider_url https://ksqtx.com.
  humanURL: https://developer.wordpress.org/rest-api/
  baseURL: https://ksqtx.com/wp-json
  tags:
  - oembed
  tags_raw:
  - oembed
  x-origin: platform-default
  properties:
  - type: OpenAPI
    url: openapi/ksq-therapeutics-oembed-api-openapi.yml
  - type: Authentication
    url: authentication/ksq-therapeutics-authentication.yml
  - type: ErrorCatalog
    url: errors/ksq-therapeutics-problem-types.yml
  - type: Conventions
    url: conventions/ksq-therapeutics-conventions.yml
  - type: DataModel
    url: data-model/ksq-therapeutics-data-model.yml
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: Website
  url: https://ksqtx.com/
- type: About
  url: https://ksqtx.com/about/
- type: Platform
  url: https://ksqtx.com/platform/
- type: Pipeline
  url: https://ksqtx.com/pipeline/
- type: Partners
  url: https://ksqtx.com/partners/
- type: Blog
  url: https://ksqtx.com/news/
- type: BlogRSS
  url: https://ksqtx.com/feed/
- type: News
  url: https://ksqtx.com/press-releases/
- type: Careers
  url: https://ksqtx.com/careers/
- type: Support
  url: https://ksqtx.com/contact-us/
- type: PatientResources
  url: https://ksqtx.com/eap/
- type: GitHubOrganization
  url: https://github.com/ksqtx
- type: SourceCode
  url: https://github.com/ksqtx/TRACE
- type: LinkedIn
  url: https://www.linkedin.com/company/10414448/
- type: Twitter
  url: https://twitter.com/KSQ_TX
- type: SecondaryMarket
  url: https://forgeglobal.com/ksq-therapeutics_stock/
- type: Authentication
  url: authentication/ksq-therapeutics-authentication.yml
- type: Conventions
  url: conventions/ksq-therapeutics-conventions.yml
- type: Conformance
  url: conformance/ksq-therapeutics-conformance.yml
- type: ErrorCatalog
  url: errors/ksq-therapeutics-problem-types.yml
- type: Lifecycle
  url: lifecycle/ksq-therapeutics-lifecycle.yml
- type: DataModel
  url: data-model/ksq-therapeutics-data-model.yml
- type: Overlay
  url: overlays/ksq-therapeutics-content-overlay.yaml
- type: DomainSecurity
  url: security/ksq-therapeutics-domain-security.yml
- type: LLMsTxt
  url: llms/ksq-therapeutics-llms.txt
- type: Packages
  url: packages/ksq-therapeutics-packages.yml
- type: CLI
  url: cli/ksq-therapeutics-cli.yml
- type: Plans
  url: plans/ksq-therapeutics-plans-pricing.yml
- type: RateLimits
  url: rate-limits/ksq-therapeutics-rate-limits.yml
- type: AgentSkill
  url: skills/_index.yml
x-enrichment:
  date: '2026-08-23'
  status: enriched
  artifacts_added: 29
  pass: local-v1
x-coverage:
  state: covered
  reason: platform-surface-only
  detail: KSQ Therapeutics is a clinical-stage biotech with no developer program and no product API — /openapi.json, /swagger.json,
    /api-docs, /docs, /redoc and /graphql all 404 on ksqtx.com, every /.well-known/ path 404s including both agent-card locations,
    and api./docs./developer.ksqtx.com resolve only to a wildcard GoDaddy parking address with no matching TLS certificate
    — but the corporate WordPress site serves a live, anonymously readable REST content API at https://ksqtx.com/wp-json (349
    routes, 9 namespaces) plus an All in One SEO generated /llms.txt, and the company publishes first-party open-source bioinformatics
    code at github.com/ksqtx; that is what this profile captures.
  evidence:
  - url: https://ksqtx.com/openapi.json
    status: 404
  - url: https://ksqtx.com/.well-known/agent-card.json
    status: 404
  - url: https://ksqtx.com/.well-known/api-catalog
    status: 404
  - url: https://ksqtx.com/wp-json
    status: 200
  - url: https://ksqtx.com/wp-json/wp/v2/press_release
    status: 200
  - url: https://ksqtx.com/wp-json/mcp
    status: 404
  - url: https://ksqtx.com/llms.txt
    status: 200
  - url: https://github.com/ksqtx
    status: 200
  checked: '2026-08-23'

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