Korro Bio
Korro Bio, Inc. (Nasdaq: KRRO) is a Cambridge, Massachusetts clinical-stage biopharmaceutical company developing a new class of genetic medicines based on programmable RNA editing. Its proprietary OPERA (Oligonucleotide Promoted Editing of RNA) platform pairs data-driven oligonucleotide design and machine-learning optimization with linker chemistry and tissue-directed delivery to recruit the body's own ADAR enzymes and make a precise, transient single-base edit to a native mRNA transcript — editing RNA rather than DNA so the change is tunable and reversible. The company was created and incubated by Atlas Venture with New Enterprise Associates in October 2019, raised a $91.5M Series A and a $116M Series B, and became public in 2023 through a merger with Frequency Therapeutics alongside a $117M private placement. Its pipeline targets liver and central nervous system indications and includes KRRO-110 (the REWRITE Phase 1/2a study in alpha-1 antitrypsin deficiency), KRRO-111 and KRRO-121, which holds EMA orphan drug designation for urea cycle disorders. Korro Bio sells therapeutics, not software: it operates no developer program, publishes no API, SDK or machine-readable specification, and maintains no public source-code organization.
Korro Bio is profiled on the APIs.io network. Tagged areas include Company, Biotechnology, Pharmaceuticals, RNA Editing, and Genetic Medicine.
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