Kartos Therapeutics

Kartos Therapeutics, Inc. is a privately held, clinical-stage biopharmaceutical company headquartered at 275 Shoreline Drive, Redwood City, California, developing navtemadlin (KRT-232), an orally administered, potent and selective small-molecule inhibitor of MDM2. The company was founded in 2016 by Wayne Rothbaum, president of Quogue Capital and co-founder of Acerta Pharma, around an MDM2 inhibitor in-licensed from Amgen. Navtemadlin blocks the MDM2 protein that suppresses p53, restoring p53 function in tumours that retain wild-type TP53 and driving cell-cycle arrest through p21 and apoptosis through pro-apoptotic Bcl-2 family proteins. The clinical programme is centred on myelofibrosis and includes the enrolling global Phase 3 POIESIS trial of navtemadlin added to ruxolitinib (NCT06479135), the Phase 1b/2 KRT-232-109 combination study (NCT04485260), and the completed Phase 3 BOREAS study of navtemadlin versus best available therapy in JAK-inhibitor relapsed or refractory myelofibrosis (NCT03662126), with reported activity also in acute myeloid leukaemia and Merkel cell carcinoma. Kartos is led by CEO Jesse McGreivy, MD, with Srdan Verstovsek, MD, PhD as chief medical officer, and is backed by Quogue Capital, OrbiMed Advisors, Amgen, SR One, Fidelity, BlackRock, T. Rowe Price, Invus and Soleus Capital. Kartos Therapeutics runs no developer program and publishes no product API, no developer portal and no API documentation; the only machine-readable surface reachable without credentials is the WordPress REST content API behind kartosthera.com, catalogued here.

Kartos Therapeutics publishes 7 APIs on the APIs.io network, including Content API, Discovery API, Media API, and 4 more. Tagged areas include Company, Biotechnology, Pharmaceuticals, Oncology, and Hematology.

Kartos Therapeutics’ developer surface includes support, authentication, and 20 more developer resources.

🌐 Visit website 📡 Source on GitHub

18.2/100 emerging ▬ flat Agent 25/100 agent aware Full breakdown ↓
scored 2026-09-03 · rubric v0.18.2

AccessSelf serve

7 APIs

Company Biotechnology Pharmaceuticals Oncology Hematology Rare Disease Precision Medicine Clinical Trials Life Sciences content-api

Kin Score

Kin Score How this is scored →
scored 2026-09-03 · rubric v0.18.2

Composite quality — 18.2/100 · emerging

Contract Quality 2.8 / 21

Developer Ergonomics 3.1 / 17

Access Clarity 1.8 / 17

Operational Transparency 0.0 / 11

Contract Governance 0.5 / 10

Discoverability 6.3 / 9

Regulatory Posture 3.9 / 15

Agent readiness — 25/100 · agent aware

Machine-Readable Contract 18 / 18

Agentic Access Contract 0 / 10

Documented Reversibility 6 / 6

MCP Server 0 / 12

Machine-Readable Auth 10 / 10

Idempotency 9 / 9

Stable Error Semantics 8 / 8

Request/Response Examples 7 / 7

Rate-Limit Signaling 0 / 7

Typed Event Surface 0 / 6

Agent Skills 5 / 5

Well-Known Catalog 0 / 4

Consent & Bot Identity 0 / 3

A2A Agent Card 0 / 8

Dry-Run / Simulate Mode 4 / 4

Delegated User Identity 0 / 6

Protected Resource Metadata 0 / 5

Registration Without a Human 0 / 6

Agentic Commerce Surface 0 / 5

Regulatory Posture applies to this provider. Its tags matched the Health regime, so Regulatory Posture carries 15 points of the composite. If this regime is wrong for your business, say so on your provider repo — the applicability map is public and we will correct it.

The six quality facets above are damped to 85 points between them, because the conditional facet above carries the other 15. That is why each facet's contribution is shown against a damped maximum: raising a quality facet moves the composite by 85% of its nominal weight, not 100%. The full arithmetic is at apis.io/rating/.

Improve this rating by publishing the missing artifacts — every area above can be raised, and the full rubric is at apis.io/rating/. Every facet and dimension name above is a link: it opens that measurement's own page — what it means, the exact checks that feed it, how the whole catalog distributes on it, and the providers at the top of it. This rating is computed from github.com/api-evangelist/kartos-therapeutics: open an issue to ask a question, or submit a pull request to add artifacts. Submit an artifact on GitHub — free → Manage your own listing — the Influence plan, $499/mo →

Something on this page wrong about Kartos Therapeutics? Report it → Free, always, and read by a human — corrections are worked from the queue daily. Agents can file the same report through the report_correction tool on the apis.io MCP.

APIs 7

Individual APIs this provider publishes, each with its own machine-readable definition.

Agent Surfaces 3

MCP servers, agent skills, and machine-readable catalogs

WellKnown

WellKnown

LLMsTxt

LLMsTxt

AgentSkill

AgentSkill

Design & Contract 5

Pagination, idempotency, versioning, errors, and events

Conventions

Conformance

ErrorCatalog

Lifecycle

DataModel

Access & Security 2

Authentication, authorization, and security posture

Authentication

Authentication

DomainSecurity

DomainSecurity

Operate 2

Status, limits, changes, and where to get help

Contact

Contact

Support

Support

Commercial 1

Pricing, plans, and the legal terms of use

PrivacyPolicy

PrivacyPolicy

Company 3

The organization behind the API

Website

Website

About

About

LinkedIn

Other 6

Properties that don't map to a standard resource type

Overlay

Science

Research

Presentations

PatientResources

SecondaryMarket

Source (apis.yml)

aid: kartos-therapeutics
name: Kartos Therapeutics
description: Kartos Therapeutics, Inc. is a privately held, clinical-stage biopharmaceutical company headquartered at 275
  Shoreline Drive, Redwood City, California, developing navtemadlin (KRT-232), an orally administered, potent and selective
  small-molecule inhibitor of MDM2. The company was founded in 2016 by Wayne Rothbaum, president of Quogue Capital and co-founder
  of Acerta Pharma, around an MDM2 inhibitor in-licensed from Amgen. Navtemadlin blocks the MDM2 protein that suppresses p53,
  restoring p53 function in tumours that retain wild-type TP53 and driving cell-cycle arrest through p21 and apoptosis through
  pro-apoptotic Bcl-2 family proteins. The clinical programme is centred on myelofibrosis and includes the enrolling global
  Phase 3 POIESIS trial of navtemadlin added to ruxolitinib (NCT06479135), the Phase 1b/2 KRT-232-109 combination study (NCT04485260),
  and the completed Phase 3 BOREAS study of navtemadlin versus best available therapy in JAK-inhibitor relapsed or refractory
  myelofibrosis (NCT03662126), with reported activity also in acute myeloid leukaemia and Merkel cell carcinoma. Kartos is
  led by CEO Jesse McGreivy, MD, with Srdan Verstovsek, MD, PhD as chief medical officer, and is backed by Quogue Capital,
  OrbiMed Advisors, Amgen, SR One, Fidelity, BlackRock, T. Rowe Price, Invus and Soleus Capital. Kartos Therapeutics runs
  no developer program and publishes no product API, no developer portal and no API documentation; the only machine-readable
  surface reachable without credentials is the WordPress REST content API behind kartosthera.com, catalogued here.
deliveryModel:
  model: unknown
  open_source: false
  commercial: false
  callable_host: true
  label: Delivery model not determined — needs a product licence on record
  confidence: low
  source:
  - openapi
  generated: '2026-08-28'
  method: derived
accessModel:
  pricing: unknown
  onboarding: self-serve
  trial: false
  try_now: false
  public: false
  label: Self-serve signup
  confidence: low
  source:
  - authentication
  - security
  generated: '2026-09-02'
  method: derived
image: https://kartosthera.com/wp-content/uploads/2025/10/og_kartos-therapeutics.jpg
url: https://raw.githubusercontent.com/api-evangelist/kartos-therapeutics/refs/heads/main/apis.yml
x-type: company
x-source: harvest:secondary-market
x-tier: profiled
x-tier-reason: enriched
specificationVersion: '0.23'
created: '2026-08-04'
modified: '2026-08-04'
tags:
- Company
- Biotechnology
- Pharmaceuticals
- Oncology
- Hematology
- Rare Disease
- Precision Medicine
- Clinical Trials
- Life Sciences
- content-api
tags_raw:
- Company
- biotechnology
- pharmaceuticals
- oncology
- hematology
- rare-disease
- precision-medicine
- clinical-trials
- life-sciences
- content-api
apis:
- aid: kartos-therapeutics:kartos-therapeutics-content-api
  name: Kartos Therapeutics Content API
  description: Published pages and the site-wide search index.
  humanURL: https://developer.wordpress.org/rest-api/
  baseURL: https://kartosthera.com/wp-json
  tags:
  - Content
  tags_raw:
  - content
  properties:
  - type: OpenAPI
    url: openapi/kartos-therapeutics-content-api-openapi.yml
  - type: Authentication
    url: authentication/kartos-therapeutics-authentication.yml
  - type: ErrorCatalog
    url: errors/kartos-therapeutics-problem-types.yml
  - type: Conventions
    url: conventions/kartos-therapeutics-conventions.yml
  - type: DataModel
    url: data-model/kartos-therapeutics-data-model.yml
- aid: kartos-therapeutics:kartos-therapeutics-discovery-api
  name: Kartos Therapeutics Discovery API
  description: The route index and namespace descriptors the site publishes about itself.
  humanURL: https://developer.wordpress.org/rest-api/
  baseURL: https://kartosthera.com/wp-json
  tags:
  - Discovery
  tags_raw:
  - discovery
  properties:
  - type: OpenAPI
    url: openapi/kartos-therapeutics-discovery-api-openapi.yml
  - type: Authentication
    url: authentication/kartos-therapeutics-authentication.yml
  - type: ErrorCatalog
    url: errors/kartos-therapeutics-problem-types.yml
  - type: Conventions
    url: conventions/kartos-therapeutics-conventions.yml
  - type: DataModel
    url: data-model/kartos-therapeutics-data-model.yml
- aid: kartos-therapeutics:kartos-therapeutics-media-api
  name: Kartos Therapeutics Media API
  description: The media library — scientific figures, investor logos and presentation PDFs.
  humanURL: https://developer.wordpress.org/rest-api/
  baseURL: https://kartosthera.com/wp-json
  tags:
  - Media
  tags_raw:
  - media
  properties:
  - type: OpenAPI
    url: openapi/kartos-therapeutics-media-api-openapi.yml
  - type: Authentication
    url: authentication/kartos-therapeutics-authentication.yml
  - type: ErrorCatalog
    url: errors/kartos-therapeutics-problem-types.yml
  - type: Conventions
    url: conventions/kartos-therapeutics-conventions.yml
  - type: DataModel
    url: data-model/kartos-therapeutics-data-model.yml
- aid: kartos-therapeutics:kartos-therapeutics-oembed-api
  name: Kartos Therapeutics Oembed API
  description: The oEmbed 1.0 provider endpoint for kartosthera.com URLs.
  humanURL: https://developer.wordpress.org/rest-api/
  baseURL: https://kartosthera.com/wp-json
  tags:
  - oEmbed
  tags_raw:
  - oembed
  properties:
  - type: OpenAPI
    url: openapi/kartos-therapeutics-oembed-api-openapi.yml
  - type: Authentication
    url: authentication/kartos-therapeutics-authentication.yml
  - type: ErrorCatalog
    url: errors/kartos-therapeutics-problem-types.yml
  - type: Conventions
    url: conventions/kartos-therapeutics-conventions.yml
  - type: DataModel
    url: data-model/kartos-therapeutics-data-model.yml
- aid: kartos-therapeutics:kartos-therapeutics-people-api
  name: Kartos Therapeutics People API
  description: The leadership, board and advisor team custom post type.
  humanURL: https://developer.wordpress.org/rest-api/
  baseURL: https://kartosthera.com/wp-json
  tags:
  - People
  tags_raw:
  - people
  properties:
  - type: OpenAPI
    url: openapi/kartos-therapeutics-people-api-openapi.yml
  - type: Authentication
    url: authentication/kartos-therapeutics-authentication.yml
  - type: ErrorCatalog
    url: errors/kartos-therapeutics-problem-types.yml
  - type: Conventions
    url: conventions/kartos-therapeutics-conventions.yml
  - type: DataModel
    url: data-model/kartos-therapeutics-data-model.yml
- aid: kartos-therapeutics:kartos-therapeutics-science-api
  name: Kartos Therapeutics Science API
  description: The navtemadlin congress presentations and publications custom post type.
  humanURL: https://developer.wordpress.org/rest-api/
  baseURL: https://kartosthera.com/wp-json
  tags:
  - Science
  tags_raw:
  - science
  properties:
  - type: OpenAPI
    url: openapi/kartos-therapeutics-science-api-openapi.yml
  - type: Authentication
    url: authentication/kartos-therapeutics-authentication.yml
  - type: ErrorCatalog
    url: errors/kartos-therapeutics-problem-types.yml
  - type: Conventions
    url: conventions/kartos-therapeutics-conventions.yml
  - type: DataModel
    url: data-model/kartos-therapeutics-data-model.yml
- aid: kartos-therapeutics:kartos-therapeutics-taxonomy-api
  name: Kartos Therapeutics Taxonomy API
  description: Registered post types, statuses, taxonomies and terms.
  humanURL: https://developer.wordpress.org/rest-api/
  baseURL: https://kartosthera.com/wp-json
  tags:
  - Taxonomy
  tags_raw:
  - taxonomy
  properties:
  - type: OpenAPI
    url: openapi/kartos-therapeutics-taxonomy-api-openapi.yml
  - type: Authentication
    url: authentication/kartos-therapeutics-authentication.yml
  - type: ErrorCatalog
    url: errors/kartos-therapeutics-problem-types.yml
  - type: Conventions
    url: conventions/kartos-therapeutics-conventions.yml
  - type: DataModel
    url: data-model/kartos-therapeutics-data-model.yml
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: Overlay
  url: overlays/kartos-therapeutics-content-overlay.yaml
- type: Website
  url: https://kartosthera.com/
- type: About
  url: https://kartosthera.com/about/
- type: Science
  url: https://kartosthera.com/science/
- type: Research
  url: https://kartosthera.com/research/
- type: Presentations
  url: https://kartosthera.com/presentations/
- type: PatientResources
  url: https://kartosthera.com/advocacy/
- type: Contact
  url: https://kartosthera.com/contact/
- type: Support
  url: https://kartosthera.com/contact/
- type: PrivacyPolicy
  url: https://kartosthera.com/privacy-policy/
- type: LinkedIn
  url: https://www.linkedin.com/company/kartos-therapeutics
- type: SecondaryMarket
  url: https://forgeglobal.com/kartos-therapeutics_stock/
- type: Authentication
  url: authentication/kartos-therapeutics-authentication.yml
- type: Conventions
  url: conventions/kartos-therapeutics-conventions.yml
- type: Conformance
  url: conformance/kartos-therapeutics-conformance.yml
- type: ErrorCatalog
  url: errors/kartos-therapeutics-problem-types.yml
- type: Lifecycle
  url: lifecycle/kartos-therapeutics-lifecycle.yml
- type: DataModel
  url: data-model/kartos-therapeutics-data-model.yml
- type: WellKnown
  url: well-known/kartos-therapeutics-well-known.yml
- type: DomainSecurity
  url: security/kartos-therapeutics-domain-security.yml
- type: LLMsTxt
  url: llms/kartos-therapeutics-llms.txt
- type: AgentSkill
  url: skills/_index.yml
x-enrichment:
  date: '2026-08-04'
  status: enriched
  artifacts_added: 15
  pass: local-v1

Work with this as data

Every provider here is available over the APIs.io API and to AI agents over MCP.

MCP server

One button, every client — Claude, Cursor, VS Code and the rest.

https://apis.io/mcp

Tools for providers

9 MCP tools reach this

find_providersBrowse and filter every provider in the catalog.
get_provider_artifactsEvery artifact this provider publishes, grouped by type.
get_provider_operationsEvery operation across all of their OpenAPIs — one call instead of parsing every spec.
get_provider_toolsEvery MCP tool they ship, with the operation each wraps.
get_provider_evidenceHow each part of their score was established. Free — the basis for a claim should not sit behind it.
get_provider_ratingPRO — composite, band, trend and facet scores.
apis_io_searchSTART HERE — APIs, providers and tags for one query, each with its total.
resolveTurn a domain, URL or GitHub org into the provider it belongs to.
find_cohortsEvery scored population of providers in the catalog.

All 92 tools →

Call it yourself

curl for this page

This provider

curl "https://apis.io/api/v1/providers/kartos-therapeutics"

All providers

curl "https://apis.io/api/v1/providers?limit=25"

Every operation they expose

curl "https://apis.io/api/v1/providers/kartos-therapeutics/operations?limit=25"

How their score was established

curl "https://apis.io/api/v1/providers/kartos-therapeutics/evidence"

Discovery needs no key. Ratings and market analysis are Pro.

Get an API key

Free tier, no email required.

GitHub Google LinkedIn

A second provider on the same verified email joins the account you already have.

Kartos Therapeutics

Kin Score

APIs 7

Kartos Therapeutics Content API

Kartos Therapeutics Discovery API

Kartos Therapeutics Media API

Kartos Therapeutics Oembed API

Kartos Therapeutics People API

Kartos Therapeutics Science API

Kartos Therapeutics Taxonomy API

Open Collections 8

API Collection

Kartos Therapeutics Content API

Kartos Therapeutics Content Discovery API

Kartos Therapeutics Content Media API

Kartos Therapeutics Content Oembed API

Kartos Therapeutics Content People API

Kartos Therapeutics Content Science API

Kartos Therapeutics Content Taxonomy API

Security Posture 2

Kartos Therapeutics Authentication

Kartos Therapeutics Domain Security

Resources