Kartos Therapeutics website screenshot

Kartos Therapeutics

Kartos Therapeutics, Inc. is a privately held, clinical-stage biopharmaceutical company headquartered at 275 Shoreline Drive, Redwood City, California, developing navtemadlin (KRT-232), an orally administered, potent and selective small-molecule inhibitor of MDM2. The company was founded in 2016 by Wayne Rothbaum, president of Quogue Capital and co-founder of Acerta Pharma, around an MDM2 inhibitor in-licensed from Amgen. Navtemadlin blocks the MDM2 protein that suppresses p53, restoring p53 function in tumours that retain wild-type TP53 and driving cell-cycle arrest through p21 and apoptosis through pro-apoptotic Bcl-2 family proteins. The clinical programme is centred on myelofibrosis and includes the enrolling global Phase 3 POIESIS trial of navtemadlin added to ruxolitinib (NCT06479135), the Phase 1b/2 KRT-232-109 combination study (NCT04485260), and the completed Phase 3 BOREAS study of navtemadlin versus best available therapy in JAK-inhibitor relapsed or refractory myelofibrosis (NCT03662126), with reported activity also in acute myeloid leukaemia and Merkel cell carcinoma. Kartos is led by CEO Jesse McGreivy, MD, with Srdan Verstovsek, MD, PhD as chief medical officer, and is backed by Quogue Capital, OrbiMed Advisors, Amgen, SR One, Fidelity, BlackRock, T. Rowe Price, Invus and Soleus Capital. Kartos Therapeutics runs no developer program and publishes no product API, no developer portal and no API documentation; the only machine-readable surface reachable without credentials is the WordPress REST content API behind kartosthera.com, catalogued here.

Kartos Therapeutics publishes 7 APIs on the APIs.io network, including Content API, Discovery API, Media API, and 4 more. Tagged areas include Company, biotechnology, pharmaceuticals, oncology, and hematology.

Kartos Therapeutics’ developer surface includes support, authentication, and 20 more developer resources.

🌐 Visit website 📡 Source on GitHub
19.7/100 emerging ▬ flat Agent 33/100 agent aware Full breakdown ↓
scored 2026-08-12 · rubric v0.11.0
7 APIs
Companybiotechnologypharmaceuticalsoncologyhematologyrare-diseaseprecision-medicineclinical-trialslife-sciencescontent-api

Kin Score

Kin Score Kin Score How this is scored →
scored 2026-08-12 · rubric v0.11.0
Composite quality — 19.7/100 · emerging
Contract Quality 3.1 / 21
Developer Ergonomics 2.9 / 17
Commercial Clarity 1.8 / 17
Operational Transparency 0.0 / 11
Governance 1.2 / 10
Discoverability 6.9 / 9
Regulatory Posture 3.9 / 15
Agent readiness — 33/100 · agent aware
Machine-Readable Contract 18 / 18
Agentic Access Contract 0 / 10
MCP Server 0 / 12
Machine-Readable Auth 10 / 10
Idempotency 0 / 9
Stable Error Semantics 8 / 8
Request/Response Examples 7 / 7
Rate-Limit Signaling 0 / 7
Typed Event Surface 0 / 6
Agent Skills 5 / 5
Well-Known Catalog 0 / 4
Consent & Bot Identity 0 / 3
A2A Agent Card 0 / 8
Dry-Run / Simulate Mode 0 / 4
Regulatory Posture applies to this provider. Its tags matched the Health regime, so Regulatory Posture carries 15 points of the composite. If this regime is wrong for your business, say so on your provider repo — the applicability map is public and we will correct it.
The six quality facets above are damped to 85 points between them, because the conditional facet above carries the other 15. That is why each facet's contribution is shown against a damped maximum: raising a quality facet moves the composite by 85% of its nominal weight, not 100%. The full arithmetic is at apis.io/rating/.
Improve this rating by publishing the missing artifacts — every area above can be raised, and the full rubric is at apis.io/rating/. This rating is computed from github.com/api-evangelist/kartos-therapeutics: open an issue to ask a question, or submit a pull request to add artifacts. Want it done for you? Prioritized profiling — $2,500 →

APIs 7

Individual APIs this provider publishes, each with its own machine-readable definition.

Kartos Therapeutics Content API

Published pages and the site-wide search index.

Kartos Therapeutics Discovery API

The route index and namespace descriptors the site publishes about itself.

Kartos Therapeutics Media API

The media library — scientific figures, investor logos and presentation PDFs.

Kartos Therapeutics Oembed API

The oEmbed 1.0 provider endpoint for kartosthera.com URLs.

Kartos Therapeutics People API

The leadership, board and advisor team custom post type.

Kartos Therapeutics Science API

The navtemadlin congress presentations and publications custom post type.

Kartos Therapeutics Taxonomy API

Registered post types, statuses, taxonomies and terms.

Scroll for all 7

Security Posture 2

Authentication, domain security, vulnerability disclosure, and trust-center signals.

Kartos Therapeutics Authentication

http · 1 scheme

SECURITY

Kartos Therapeutics Domain Security

TLSv1.3 · HSTS · DMARC

SECURITY

Resources

Agent Surfaces 3

MCP servers, agent skills, and machine-readable catalogs

WellKnown
WellKnown
 LLMsTxt
LLMsTxt
 AgentSkill
AgentSkill

Design & Contract 5

Pagination, idempotency, versioning, errors, and events

Conventions
Conventions
 Conformance
Conformance
 ErrorCatalog
ErrorCatalog
 Lifecycle
Lifecycle
 DataModel
DataModel

Access & Security 2

Authentication, authorization, and security posture

Authentication
Authentication
 DomainSecurity
DomainSecurity

Operate 2

Status, limits, changes, and where to get help

Contact
Contact
 Support
Support

Commercial 1

Pricing, plans, and the legal terms of use

PrivacyPolicy
PrivacyPolicy

Company 3

The organization behind the API

Website
Website
 About
About
 LinkedIn
LinkedIn

Other 6

Properties that don't map to a standard resource type

Overlay
Overlay
 Science
Science
 Research
Research
 Presentations
Presentations
 PatientResources
PatientResources
 SecondaryMarket
SecondaryMarket

Source (apis.yml)

apis.yml Raw ↑ 
aid: kartos-therapeutics
name: Kartos Therapeutics
description: Kartos Therapeutics, Inc. is a privately held, clinical-stage biopharmaceutical company headquartered at 275
  Shoreline Drive, Redwood City, California, developing navtemadlin (KRT-232), an orally administered, potent and selective
  small-molecule inhibitor of MDM2. The company was founded in 2016 by Wayne Rothbaum, president of Quogue Capital and co-founder
  of Acerta Pharma, around an MDM2 inhibitor in-licensed from Amgen. Navtemadlin blocks the MDM2 protein that suppresses p53,
  restoring p53 function in tumours that retain wild-type TP53 and driving cell-cycle arrest through p21 and apoptosis through
  pro-apoptotic Bcl-2 family proteins. The clinical programme is centred on myelofibrosis and includes the enrolling global
  Phase 3 POIESIS trial of navtemadlin added to ruxolitinib (NCT06479135), the Phase 1b/2 KRT-232-109 combination study (NCT04485260),
  and the completed Phase 3 BOREAS study of navtemadlin versus best available therapy in JAK-inhibitor relapsed or refractory
  myelofibrosis (NCT03662126), with reported activity also in acute myeloid leukaemia and Merkel cell carcinoma. Kartos is
  led by CEO Jesse McGreivy, MD, with Srdan Verstovsek, MD, PhD as chief medical officer, and is backed by Quogue Capital,
  OrbiMed Advisors, Amgen, SR One, Fidelity, BlackRock, T. Rowe Price, Invus and Soleus Capital. Kartos Therapeutics runs
  no developer program and publishes no product API, no developer portal and no API documentation; the only machine-readable
  surface reachable without credentials is the WordPress REST content API behind kartosthera.com, catalogued here.
image: https://kartosthera.com/wp-content/uploads/2025/10/og_kartos-therapeutics.jpg
url: https://raw.githubusercontent.com/api-evangelist/kartos-therapeutics/refs/heads/main/apis.yml
x-type: company
x-source: harvest:secondary-market
x-tier: profiled
x-tier-reason: enriched
specificationVersion: '0.20'
created: '2026-08-04'
modified: '2026-08-04'
tags:
- Company
- biotechnology
- pharmaceuticals
- oncology
- hematology
- rare-disease
- precision-medicine
- clinical-trials
- life-sciences
- content-api
apis:
- aid: kartos-therapeutics:kartos-therapeutics-content-api
  name: Kartos Therapeutics Content API
  description: Published pages and the site-wide search index.
  humanURL: https://developer.wordpress.org/rest-api/
  baseURL: https://kartosthera.com/wp-json
  tags:
  - content
  properties:
  - type: OpenAPI
    url: openapi/kartos-therapeutics-content-api-openapi.yml
  - type: Authentication
    url: authentication/kartos-therapeutics-authentication.yml
  - type: ErrorCatalog
    url: errors/kartos-therapeutics-problem-types.yml
  - type: Conventions
    url: conventions/kartos-therapeutics-conventions.yml
  - type: DataModel
    url: data-model/kartos-therapeutics-data-model.yml
- aid: kartos-therapeutics:kartos-therapeutics-discovery-api
  name: Kartos Therapeutics Discovery API
  description: The route index and namespace descriptors the site publishes about itself.
  humanURL: https://developer.wordpress.org/rest-api/
  baseURL: https://kartosthera.com/wp-json
  tags:
  - discovery
  properties:
  - type: OpenAPI
    url: openapi/kartos-therapeutics-discovery-api-openapi.yml
  - type: Authentication
    url: authentication/kartos-therapeutics-authentication.yml
  - type: ErrorCatalog
    url: errors/kartos-therapeutics-problem-types.yml
  - type: Conventions
    url: conventions/kartos-therapeutics-conventions.yml
  - type: DataModel
    url: data-model/kartos-therapeutics-data-model.yml
- aid: kartos-therapeutics:kartos-therapeutics-media-api
  name: Kartos Therapeutics Media API
  description: The media library — scientific figures, investor logos and presentation PDFs.
  humanURL: https://developer.wordpress.org/rest-api/
  baseURL: https://kartosthera.com/wp-json
  tags:
  - media
  properties:
  - type: OpenAPI
    url: openapi/kartos-therapeutics-media-api-openapi.yml
  - type: Authentication
    url: authentication/kartos-therapeutics-authentication.yml
  - type: ErrorCatalog
    url: errors/kartos-therapeutics-problem-types.yml
  - type: Conventions
    url: conventions/kartos-therapeutics-conventions.yml
  - type: DataModel
    url: data-model/kartos-therapeutics-data-model.yml
- aid: kartos-therapeutics:kartos-therapeutics-oembed-api
  name: Kartos Therapeutics Oembed API
  description: The oEmbed 1.0 provider endpoint for kartosthera.com URLs.
  humanURL: https://developer.wordpress.org/rest-api/
  baseURL: https://kartosthera.com/wp-json
  tags:
  - oembed
  properties:
  - type: OpenAPI
    url: openapi/kartos-therapeutics-oembed-api-openapi.yml
  - type: Authentication
    url: authentication/kartos-therapeutics-authentication.yml
  - type: ErrorCatalog
    url: errors/kartos-therapeutics-problem-types.yml
  - type: Conventions
    url: conventions/kartos-therapeutics-conventions.yml
  - type: DataModel
    url: data-model/kartos-therapeutics-data-model.yml
- aid: kartos-therapeutics:kartos-therapeutics-people-api
  name: Kartos Therapeutics People API
  description: The leadership, board and advisor team custom post type.
  humanURL: https://developer.wordpress.org/rest-api/
  baseURL: https://kartosthera.com/wp-json
  tags:
  - people
  properties:
  - type: OpenAPI
    url: openapi/kartos-therapeutics-people-api-openapi.yml
  - type: Authentication
    url: authentication/kartos-therapeutics-authentication.yml
  - type: ErrorCatalog
    url: errors/kartos-therapeutics-problem-types.yml
  - type: Conventions
    url: conventions/kartos-therapeutics-conventions.yml
  - type: DataModel
    url: data-model/kartos-therapeutics-data-model.yml
- aid: kartos-therapeutics:kartos-therapeutics-science-api
  name: Kartos Therapeutics Science API
  description: The navtemadlin congress presentations and publications custom post type.
  humanURL: https://developer.wordpress.org/rest-api/
  baseURL: https://kartosthera.com/wp-json
  tags:
  - science
  properties:
  - type: OpenAPI
    url: openapi/kartos-therapeutics-science-api-openapi.yml
  - type: Authentication
    url: authentication/kartos-therapeutics-authentication.yml
  - type: ErrorCatalog
    url: errors/kartos-therapeutics-problem-types.yml
  - type: Conventions
    url: conventions/kartos-therapeutics-conventions.yml
  - type: DataModel
    url: data-model/kartos-therapeutics-data-model.yml
- aid: kartos-therapeutics:kartos-therapeutics-taxonomy-api
  name: Kartos Therapeutics Taxonomy API
  description: Registered post types, statuses, taxonomies and terms.
  humanURL: https://developer.wordpress.org/rest-api/
  baseURL: https://kartosthera.com/wp-json
  tags:
  - taxonomy
  properties:
  - type: OpenAPI
    url: openapi/kartos-therapeutics-taxonomy-api-openapi.yml
  - type: Authentication
    url: authentication/kartos-therapeutics-authentication.yml
  - type: ErrorCatalog
    url: errors/kartos-therapeutics-problem-types.yml
  - type: Conventions
    url: conventions/kartos-therapeutics-conventions.yml
  - type: DataModel
    url: data-model/kartos-therapeutics-data-model.yml
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: Overlay
  url: overlays/kartos-therapeutics-content-overlay.yaml
- type: Website
  url: https://kartosthera.com/
- type: About
  url: https://kartosthera.com/about/
- type: Science
  url: https://kartosthera.com/science/
- type: Research
  url: https://kartosthera.com/research/
- type: Presentations
  url: https://kartosthera.com/presentations/
- type: PatientResources
  url: https://kartosthera.com/advocacy/
- type: Contact
  url: https://kartosthera.com/contact/
- type: Support
  url: https://kartosthera.com/contact/
- type: PrivacyPolicy
  url: https://kartosthera.com/privacy-policy/
- type: LinkedIn
  url: https://www.linkedin.com/company/kartos-therapeutics
- type: SecondaryMarket
  url: https://forgeglobal.com/kartos-therapeutics_stock/
- type: Authentication
  url: authentication/kartos-therapeutics-authentication.yml
- type: Conventions
  url: conventions/kartos-therapeutics-conventions.yml
- type: Conformance
  url: conformance/kartos-therapeutics-conformance.yml
- type: ErrorCatalog
  url: errors/kartos-therapeutics-problem-types.yml
- type: Lifecycle
  url: lifecycle/kartos-therapeutics-lifecycle.yml
- type: DataModel
  url: data-model/kartos-therapeutics-data-model.yml
- type: WellKnown
  url: well-known/kartos-therapeutics-well-known.yml
- type: DomainSecurity
  url: security/kartos-therapeutics-domain-security.yml
- type: LLMsTxt
  url: llms/kartos-therapeutics-llms.txt
- type: AgentSkill
  url: skills/_index.yml
x-enrichment:
  date: '2026-08-04'
  status: enriched
  artifacts_added: 15
  pass: local-v1