Kallyope

Kallyope, Inc. is a New York City clinical-stage biotechnology company, founded in 2015 by Columbia University scientists Charles Zuker, Tom Maniatis and Richard Axel, that translates the biology of the gut-brain axis into medicines. It launched with a $44M Series A and has since raised a $66M Series B, a $112M Series C and a $236M Series D co-led by Mubadala Investment Company and The Column Group, with backers including Bill Gates, Lux Capital, Polaris Partners, Casdin Capital and Alexandria Real Estate Equities. Its proprietary Klarity platform integrates single-cell sequencing, pathway circuit mapping, optogenetics and chemogenetics, proprietary human genetics, mouse and human organoid systems, and small-molecule and peptide chemistry to map the neural circuits underlying migraine and metabolism; lead candidate elismetrep, a TRPM8 blocker, is in Phase 3 development for acute migraine. Kallyope publishes no developer portal, API reference, SDKs, CLI, status page or public GitHub organization, and no OpenAPI, AsyncAPI, GraphQL, MCP or A2A agent-card surface was found on any host. Enrichment probing did find one real, anonymous, read-only REST surface: kallyope.com runs WordPress and exposes the WordPress REST API publicly at https://kallyope.com/wp-json, carrying the company news feed, site pages, media library and a first-party "document" content type of scientific posters, presentations and publications classified by the custom program, event, content-type and document-type taxonomies.

Kallyope publishes 6 APIs on the APIs.io network, including Discovery API, Documents API, Media API, and 3 more. Tagged areas include Company, Biotechnology, Life Sciences, Pharmaceuticals, and Drug Discovery.

The Kallyope catalog on APIs.io includes 1 JSON-LD context.

Kallyope’s developer surface includes engineering blog, support, and 13 more developer resources.

🌐 Visit website 📡 Source on GitHub

16.4/100 emerging ▬ flat Agent 22/100 agent aware Full breakdown ↓
scored 2026-09-14 · rubric v0.22.0

6 APIs

Company Biotechnology Life Sciences Pharmaceuticals Drug Discovery NeuroscienceGut-Brain AxisMigraine Metabolic Disease Clinical Trials Content

Kin Score

Kin Score How this is scored →
scored 2026-09-14 · rubric v0.22.0

Composite quality — 16.4/100 · emerging

Contract Quality 3.3 / 21

Developer Ergonomics 3.5 / 17

Access Clarity 0.0 / 17

Operational Transparency 0.0 / 11

Contract Governance 0.5 / 10

Discoverability 6.3 / 9

Regulatory Posture 3.2 / 15

Agent readiness — 22/100 · agent aware

Machine-Readable Contract 18 / 18

Agentic Access Contract 0 / 10

Documented Reversibility 6 / 6

MCP Server 0 / 12

Machine-Readable Auth 10 / 10

Idempotency 9 / 9

Stable Error Semantics 8 / 8

Request/Response Examples 0 / 7

Rate-Limit Signaling 0 / 7

Typed Event Surface 0 / 6

Agent Skills 5 / 5

Well-Known Catalog 0 / 4

Consent & Bot Identity 0 / 3

A2A Agent Card 0 / 8

Dry-Run / Simulate Mode 4 / 4

Delegated User Identity 0 / 6

Protected Resource Metadata 0 / 5

Registration Without a Human 0 / 6

Agentic Commerce Well-Known Document 0 / 5

Regulatory Posture applies to this provider. Its tags matched the Health regime, so Regulatory Posture carries 15 points of the composite. If this regime is wrong for your business, say so on your provider repo — the applicability map is public and we will correct it.

Create-or-Update Ergonomics does not apply to this provider. The published contracts declare no write operations, and a read-only API cannot create-or-update. The facet is excluded from this provider's denominator entirely — not scored zero. A reference or data API is not deficient for being unable to upsert.

The six quality facets above are damped to 85 points between them, because the conditional facet above carries the other 15. That is why each facet's contribution is shown against a damped maximum: raising a quality facet moves the composite by 85% of its nominal weight, not 100%. The full arithmetic is at apis.io/rating/.

Improve this rating by publishing the missing artifacts — every area above can be raised, and the full rubric is at apis.io/rating/. Every facet and dimension name above is a link: it opens that measurement's own page — what it means, the exact checks that feed it, how the whole catalog distributes on it, and the providers at the top of it. This rating is computed from github.com/api-evangelist/kallyope: open an issue to ask a question, or submit a pull request to add artifacts. Submit an artifact on GitHub — free → Manage your own listing — the Influence plan, $499/mo →

APIs 6

Individual APIs this provider publishes, each with its own machine-readable definition.

Kallyope Discovery API

Site-wide search and the registered post-type / taxonomy indexes.

Kallyope Documents API

Kallyope's first-party library of scientific posters, presentations, publications and video.

Kallyope Media API

The uploaded media library backing documents and pages.

Kallyope News API

Company news and press-release posts.

Kallyope Pages API

Site pages (about, pipeline, platform, partnering, careers, contact).

Kallyope Taxonomies API

The first-party program / event / content-type / document-type classifications applied to documents.

Open Collections 1

Open, tool-agnostic API collections (OpenAPI-derived and Bruno).

Kallyope Content REST API (derived)

OPEN COLLECTION

Semantic Vocabularies 1

JSON-LD contexts and semantic vocabularies used across these APIs.

Kallyope Organization Context

0 classes · 0 properties

JSON-LD

Security Posture 2

Authentication, domain security, vulnerability disclosure, and trust-center signals.

Kallyope Authentication

none/http · 3 schemes

SECURITY

Kallyope Domain Security

TLSv1.3 · HSTS · DMARC

SECURITY

Resources

Agent Surfaces 4

MCP servers, agent skills, and machine-readable catalogs

X-MCPServerCandidate

AgentSkill

WellKnown

LLMsTxt

Design & Contract 2

Pagination, idempotency, versioning, errors, and events

Conformance

Conformance

JSONLD

JSONLD

Access & Security 1

Authentication, authorization, and security posture

DomainSecurity

DomainSecurity

Operate 1

Status, limits, changes, and where to get help

Support

Support

Company 6

The organization behind the API

Website

About

Blog

Careers

Partners

LinkedIn

Other 1

Properties that don't map to a standard resource type

Overlay

Overlay

Source (apis.yml)

aid: kallyope
name: Kallyope
description: 'Kallyope, Inc. is a New York City clinical-stage biotechnology company, founded in 2015 by Columbia University
  scientists Charles Zuker, Tom Maniatis and Richard Axel, that translates the biology of the gut-brain axis into medicines.
  It launched with a $44M Series A and has since raised a $66M Series B, a $112M Series C and a $236M Series D co-led by Mubadala
  Investment Company and The Column Group, with backers including Bill Gates, Lux Capital, Polaris Partners, Casdin Capital
  and Alexandria Real Estate Equities. Its proprietary Klarity platform integrates single-cell sequencing, pathway circuit
  mapping, optogenetics and chemogenetics, proprietary human genetics, mouse and human organoid systems, and small-molecule
  and peptide chemistry to map the neural circuits underlying migraine and metabolism; lead candidate elismetrep, a TRPM8
  blocker, is in Phase 3 development for acute migraine. Kallyope publishes no developer portal, API reference, SDKs, CLI,
  status page or public GitHub organization, and no OpenAPI, AsyncAPI, GraphQL, MCP or A2A agent-card surface was found on
  any host. Enrichment probing did find one real, anonymous, read-only REST surface: kallyope.com runs WordPress and exposes
  the WordPress REST API publicly at https://kallyope.com/wp-json, carrying the company news feed, site pages, media library
  and a first-party "document" content type of scientific posters, presentations and publications classified by the custom
  program, event, content-type and document-type taxonomies.'
deliveryModel:
  model: unknown
  open_source: false
  commercial: false
  callable_host: true
  label: Delivery model not determined — needs a product licence on record
  confidence: low
  source:
  - openapi
  generated: '2026-08-28'
  method: derived
accessModel:
  pricing: unknown
  onboarding: unknown
  trial: false
  try_now: false
  public: false
  label: Unknown
  confidence: low
  source:
  - authentication
  - security
  generated: '2026-09-03'
  method: derived
image: https://kallyope.com/wp-content/uploads/2022/06/Kallyope_og.jpg
url: https://raw.githubusercontent.com/api-evangelist/kallyope/refs/heads/main/apis.yml
x-type: company
x-source: harvest:secondary-market
x-tier: stub
x-tier-reason: harvest
specificationVersion: '0.23'
created: '2026-08-01'
modified: '2026-08-01'
tags:
- Company
- Biotechnology
- Life Sciences
- Pharmaceuticals
- Drug Discovery
- Neuroscience
- Gut-Brain Axis
- Migraine
- Metabolic Disease
- Clinical Trials
- Content
apis:
- aid: kallyope:kallyope-discovery-api
  name: Kallyope Discovery API
  description: Site-wide search and the registered post-type / taxonomy indexes.
  humanURL: https://kallyope.com/
  baseURL: https://kallyope.com/wp-json
  tags:
  - Discovery
  properties:
  - type: OpenAPI
    url: openapi/kallyope-discovery-api-openapi.yml
  - type: Authentication
    url: authentication/kallyope-authentication.yml
  - type: Conventions
    url: conventions/kallyope-conventions.yml
  - type: ErrorCatalog
    url: errors/kallyope-problem-types.yml
  - type: DataModel
    url: data-model/kallyope-data-model.yml
  - type: Lifecycle
    url: lifecycle/kallyope-lifecycle.yml
  - type: ToolCrosswalk
    url: mcp/kallyope-tool-crosswalk.yml
  - type: Website
    url: https://kallyope.com/
- aid: kallyope:kallyope-documents-api
  name: Kallyope Documents API
  description: Kallyope's first-party library of scientific posters, presentations, publications and video.
  humanURL: https://kallyope.com/
  baseURL: https://kallyope.com/wp-json
  tags:
  - Documents
  properties:
  - type: OpenAPI
    url: openapi/kallyope-documents-api-openapi.yml
  - type: Authentication
    url: authentication/kallyope-authentication.yml
  - type: Conventions
    url: conventions/kallyope-conventions.yml
  - type: ErrorCatalog
    url: errors/kallyope-problem-types.yml
  - type: DataModel
    url: data-model/kallyope-data-model.yml
  - type: Lifecycle
    url: lifecycle/kallyope-lifecycle.yml
  - type: ToolCrosswalk
    url: mcp/kallyope-tool-crosswalk.yml
  - type: Website
    url: https://kallyope.com/
- aid: kallyope:kallyope-media-api
  name: Kallyope Media API
  description: The uploaded media library backing documents and pages.
  humanURL: https://kallyope.com/
  baseURL: https://kallyope.com/wp-json
  tags:
  - Media
  properties:
  - type: OpenAPI
    url: openapi/kallyope-media-api-openapi.yml
  - type: Authentication
    url: authentication/kallyope-authentication.yml
  - type: Conventions
    url: conventions/kallyope-conventions.yml
  - type: ErrorCatalog
    url: errors/kallyope-problem-types.yml
  - type: DataModel
    url: data-model/kallyope-data-model.yml
  - type: Lifecycle
    url: lifecycle/kallyope-lifecycle.yml
  - type: ToolCrosswalk
    url: mcp/kallyope-tool-crosswalk.yml
  - type: Website
    url: https://kallyope.com/
- aid: kallyope:kallyope-news-api
  name: Kallyope News API
  description: Company news and press-release posts.
  humanURL: https://kallyope.com/
  baseURL: https://kallyope.com/wp-json
  tags:
  - News
  properties:
  - type: OpenAPI
    url: openapi/kallyope-news-api-openapi.yml
  - type: Authentication
    url: authentication/kallyope-authentication.yml
  - type: Conventions
    url: conventions/kallyope-conventions.yml
  - type: ErrorCatalog
    url: errors/kallyope-problem-types.yml
  - type: DataModel
    url: data-model/kallyope-data-model.yml
  - type: Lifecycle
    url: lifecycle/kallyope-lifecycle.yml
  - type: ToolCrosswalk
    url: mcp/kallyope-tool-crosswalk.yml
  - type: Website
    url: https://kallyope.com/
- aid: kallyope:kallyope-pages-api
  name: Kallyope Pages API
  description: Site pages (about, pipeline, platform, partnering, careers, contact).
  humanURL: https://kallyope.com/
  baseURL: https://kallyope.com/wp-json
  tags:
  - Pages
  properties:
  - type: OpenAPI
    url: openapi/kallyope-pages-api-openapi.yml
  - type: Authentication
    url: authentication/kallyope-authentication.yml
  - type: Conventions
    url: conventions/kallyope-conventions.yml
  - type: ErrorCatalog
    url: errors/kallyope-problem-types.yml
  - type: DataModel
    url: data-model/kallyope-data-model.yml
  - type: Lifecycle
    url: lifecycle/kallyope-lifecycle.yml
  - type: ToolCrosswalk
    url: mcp/kallyope-tool-crosswalk.yml
  - type: Website
    url: https://kallyope.com/
- aid: kallyope:kallyope-taxonomies-api
  name: Kallyope Taxonomies API
  description: The first-party program / event / content-type / document-type classifications applied to documents.
  humanURL: https://kallyope.com/
  baseURL: https://kallyope.com/wp-json
  tags:
  - taxonomies
  tags_raw:
  - Taxonomies
  properties:
  - type: OpenAPI
    url: openapi/kallyope-taxonomies-api-openapi.yml
  - type: Authentication
    url: authentication/kallyope-authentication.yml
  - type: Conventions
    url: conventions/kallyope-conventions.yml
  - type: ErrorCatalog
    url: errors/kallyope-problem-types.yml
  - type: DataModel
    url: data-model/kallyope-data-model.yml
  - type: Lifecycle
    url: lifecycle/kallyope-lifecycle.yml
  - type: ToolCrosswalk
    url: mcp/kallyope-tool-crosswalk.yml
  - type: Website
    url: https://kallyope.com/
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: Overlay
  url: overlays/kallyope-content-api-overlay.yaml
- type: X-MCPServerCandidate
  url: mcp/kallyope-mcp.yml
  note: 'Renamed from MCPServer 2026-09-03 (roadmap#247): the manifest self-describes as status: candidate — a tool list derived
    from the published API contracts, not an existing server. The scorer already read the manifest and reported mcp_server
    correctly; the MCPServer type was crediting the artifact-type surfaces with a server that does not exist.'
- type: AgentSkill
  url: skills/_index.yml
- type: Website
  url: https://kallyope.com/
- type: About
  url: https://kallyope.com/about/
- type: Blog
  url: https://kallyope.com/news/
- type: Support
  url: https://kallyope.com/contact/
- type: Careers
  url: https://kallyope.com/careers/
- type: Partners
  url: https://kallyope.com/partnering/
- type: LinkedIn
  url: https://www.linkedin.com/company/kallyope/
- type: Conformance
  url: conformance/kallyope-conformance.yml
- type: DomainSecurity
  url: security/kallyope-domain-security.yml
- type: WellKnown
  url: well-known/kallyope-well-known.yml
- type: LLMsTxt
  url: llms/kallyope-llms.txt
- type: JSONLD
  url: json-ld/kallyope-organization.jsonld
x-enrichment:
  date: '2026-08-01'
  status: enriched
  artifacts_added: 17
  pass: local-v1

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