Kallyope website screenshot

Kallyope

Kallyope, Inc. is a New York City clinical-stage biotechnology company, founded in 2015 by Columbia University scientists Charles Zuker, Tom Maniatis and Richard Axel, that translates the biology of the gut-brain axis into medicines. It launched with a $44M Series A and has since raised a $66M Series B, a $112M Series C and a $236M Series D co-led by Mubadala Investment Company and The Column Group, with backers including Bill Gates, Lux Capital, Polaris Partners, Casdin Capital and Alexandria Real Estate Equities. Its proprietary Klarity platform integrates single-cell sequencing, pathway circuit mapping, optogenetics and chemogenetics, proprietary human genetics, mouse and human organoid systems, and small-molecule and peptide chemistry to map the neural circuits underlying migraine and metabolism; lead candidate elismetrep, a TRPM8 blocker, is in Phase 3 development for acute migraine. Kallyope publishes no developer portal, API reference, SDKs, CLI, status page or public GitHub organization, and no OpenAPI, AsyncAPI, GraphQL, MCP or A2A agent-card surface was found on any host. Enrichment probing did find one real, anonymous, read-only REST surface: kallyope.com runs WordPress and exposes the WordPress REST API publicly at https://kallyope.com/wp-json, carrying the company news feed, site pages, media library and a first-party "document" content type of scientific posters, presentations and publications classified by the custom program, event, content-type and document-type taxonomies.

Kallyope publishes 1 API on the APIs.io network: Content REST API. Tagged areas include Company, Biotechnology, Life Sciences, Pharmaceuticals, and Drug Discovery.

The Kallyope catalog on APIs.io includes 1 JSON-LD context.

Kallyope’s developer surface includes engineering blog, support, and 11 more developer resources.

13.4/100 emerging ▬ flat Agent 15/100 agent aware Full breakdown ↓
scored 2026-08-25 · rubric v0.14.0
1 APIs 1 MCP Servers
CompanyBiotechnologyLife SciencesPharmaceuticalsDrug DiscoveryNeuroscienceGut-Brain AxisMigraineMetabolic DiseaseClinical TrialsContent

Kin Score

Kin Score Kin Score How this is scored →
scored 2026-08-25 · rubric v0.14.0
Composite quality — 13.4/100 · emerging
Contract Quality 3.3 / 21
Developer Ergonomics 1.2 / 17
Access Clarity 0.0 / 17
Operational Transparency 0.0 / 11
Contract Governance 1.7 / 10
Discoverability 5.8 / 9
Regulatory Posture 2.1 / 15
Agent readiness — 15/100 · agent aware
Machine-Readable Contract 18 / 18
Agentic Access Contract 0 / 10
Documented Reversibility 6 / 6
MCP Server 0 / 12
Machine-Readable Auth 0 / 10
Idempotency 9 / 9
Stable Error Semantics 0 / 8
Request/Response Examples 0 / 7
Rate-Limit Signaling 0 / 7
Typed Event Surface 0 / 6
Agent Skills 0 / 5
Well-Known Catalog 0 / 4
Consent & Bot Identity 0 / 3
A2A Agent Card 0 / 8
Dry-Run / Simulate Mode 4 / 4
Delegated User Identity 0 / 6
Protected Resource Metadata 0 / 5
Registration Without a Human 0 / 6
Agentic Commerce Surface 0 / 5
Regulatory Posture applies to this provider. Its tags matched the Health regime, so Regulatory Posture carries 15 points of the composite. If this regime is wrong for your business, say so on your provider repo — the applicability map is public and we will correct it.
The six quality facets above are damped to 85 points between them, because the conditional facet above carries the other 15. That is why each facet's contribution is shown against a damped maximum: raising a quality facet moves the composite by 85% of its nominal weight, not 100%. The full arithmetic is at apis.io/rating/.
Improve this rating by publishing the missing artifacts — every area above can be raised, and the full rubric is at apis.io/rating/. This rating is computed from github.com/api-evangelist/kallyope: open an issue to ask a question, or submit a pull request to add artifacts. Want it done for you? Prioritized profiling — $2,500 →

APIs 1

Individual APIs this provider publishes, each with its own machine-readable definition.

Kallyope Content REST API

Anonymous, read-only REST surface behind kallyope.com. Kallyope runs WordPress and exposes the WordPress REST API publicly at https://kallyope.com/wp-json with 326 registered ro...

Open Collections 1

Open, tool-agnostic API collections (OpenAPI-derived and Bruno).

MCP Servers 1

Model Context Protocol servers that expose these APIs to AI agents.

Semantic Vocabularies 1

JSON-LD contexts and semantic vocabularies used across these APIs.

Kallyope Organization Context

0 classes · 0 properties

JSON-LD

Security Posture 2

Authentication, domain security, vulnerability disclosure, and trust-center signals.

Kallyope Authentication

none/http · 3 schemes

SECURITY

Kallyope Domain Security

TLSv1.3 · HSTS · DMARC

SECURITY

Resources

Agent Surfaces 2

MCP servers, agent skills, and machine-readable catalogs

Design & Contract 2

Pagination, idempotency, versioning, errors, and events

Access & Security 1

Authentication, authorization, and security posture

Operate 1

Status, limits, changes, and where to get help

Company 7

The organization behind the API

Scroll for all 7

Source (apis.yml)

apis.yml Raw ↑
aid: kallyope
name: Kallyope
description: 'Kallyope, Inc. is a New York City clinical-stage biotechnology company, founded in 2015 by Columbia University
  scientists Charles Zuker, Tom Maniatis and Richard Axel, that translates the biology of the gut-brain axis into medicines.
  It launched with a $44M Series A and has since raised a $66M Series B, a $112M Series C and a $236M Series D co-led by Mubadala
  Investment Company and The Column Group, with backers including Bill Gates, Lux Capital, Polaris Partners, Casdin Capital
  and Alexandria Real Estate Equities. Its proprietary Klarity platform integrates single-cell sequencing, pathway circuit
  mapping, optogenetics and chemogenetics, proprietary human genetics, mouse and human organoid systems, and small-molecule
  and peptide chemistry to map the neural circuits underlying migraine and metabolism; lead candidate elismetrep, a TRPM8
  blocker, is in Phase 3 development for acute migraine. Kallyope publishes no developer portal, API reference, SDKs, CLI,
  status page or public GitHub organization, and no OpenAPI, AsyncAPI, GraphQL, MCP or A2A agent-card surface was found on
  any host. Enrichment probing did find one real, anonymous, read-only REST surface: kallyope.com runs WordPress and exposes
  the WordPress REST API publicly at https://kallyope.com/wp-json, carrying the company news feed, site pages, media library
  and a first-party "document" content type of scientific posters, presentations and publications classified by the custom
  program, event, content-type and document-type taxonomies.'
image: https://kallyope.com/wp-content/uploads/2022/06/Kallyope_og.jpg
url: https://raw.githubusercontent.com/api-evangelist/kallyope/refs/heads/main/apis.yml
x-type: company
x-source: harvest:secondary-market
x-tier: stub
x-tier-reason: harvest
specificationVersion: '0.23'
created: '2026-08-01'
modified: '2026-08-01'
tags:
- Company
- Biotechnology
- Life Sciences
- Pharmaceuticals
- Drug Discovery
- Neuroscience
- Gut-Brain Axis
- Migraine
- Metabolic Disease
- Clinical Trials
- Content
apis:
- aid: kallyope:content-api
  name: Kallyope Content REST API
  description: 'Anonymous, read-only REST surface behind kallyope.com. Kallyope runs WordPress and exposes the WordPress REST
    API publicly at https://kallyope.com/wp-json with 326 registered routes across 14 namespaces. The publicly readable surface
    is the stock wp/v2 namespace, which Kallyope has extended with a first-party custom post type — "document" (scientific
    posters, presentations, publications and video) — and four first-party custom taxonomies that classify it: program (drug
    programs, e.g. elismetrep), event (scientific congresses such as the American Headache Society and Academy of Neurology
    annual meetings), content-type (presentation, poster, publication, video, terms-conditions) and document-type. Alongside
    those sit the core posts (company news), pages, media, categories, users, search, types and taxonomies collections. No
    authentication is required for reads and none of the write methods are reachable anonymously; no API keys, rate-limit
    headers or developer documentation are published for it. This is a content and marketing API, not a Klarity platform,
    research-data or clinical API.'
  humanURL: https://kallyope.com/
  baseURL: https://kallyope.com/wp-json
  tags:
  - Content
  - News
  - Documents
  - Publications
  - Media
  - Search
  properties:
  - type: OpenAPI
    url: openapi/kallyope-content-api-openapi.yml
  - type: Overlay
    url: overlays/kallyope-content-api-overlay.yaml
  - type: Authentication
    url: authentication/kallyope-authentication.yml
  - type: Conventions
    url: conventions/kallyope-conventions.yml
  - type: ErrorCatalog
    url: errors/kallyope-problem-types.yml
  - type: DataModel
    url: data-model/kallyope-data-model.yml
  - type: Lifecycle
    url: lifecycle/kallyope-lifecycle.yml
  - type: MCPServer
    url: mcp/kallyope-mcp.yml
  - type: ToolCrosswalk
    url: mcp/kallyope-tool-crosswalk.yml
  - type: AgentSkill
    url: skills/_index.yml
  - type: Website
    url: https://kallyope.com/
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: Website
  url: https://kallyope.com/
- type: About
  url: https://kallyope.com/about/
- type: Blog
  url: https://kallyope.com/news/
- type: Support
  url: https://kallyope.com/contact/
- type: Careers
  url: https://kallyope.com/careers/
- type: Partners
  url: https://kallyope.com/partnering/
- type: LinkedIn
  url: https://www.linkedin.com/company/kallyope/
- type: Conformance
  url: conformance/kallyope-conformance.yml
- type: DomainSecurity
  url: security/kallyope-domain-security.yml
- type: WellKnown
  url: well-known/kallyope-well-known.yml
- type: LLMsTxt
  url: llms/kallyope-llms.txt
- type: JSONLD
  url: json-ld/kallyope-organization.jsonld
- type: Website
  url: https://forgeglobal.com/kallyope_stock/
x-enrichment:
  date: '2026-08-01'
  status: enriched
  artifacts_added: 17
  pass: local-v1

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