Jnana Therapeutics

aid: jnana-therapeutics
name: Jnana Therapeutics
description: 'Jnana Therapeutics Inc. is a biotechnology company headquartered at One Design Center Place, Suite 19-400, Boston,
  Massachusetts, that built RAPID — Reactive Affinity Probe Interaction Discovery — a next-generation chemoproteomics platform
  for discovering small-molecule medicines against target classes that conventional screening has struggled to drug, including
  SLC transporters, transcription factors, signaling scaffold proteins, phosphatases, GPCRs and helicases. RAPID runs in living
  cells: a proprietary Reactive Affinity Probe library covalently labels druggable pockets on a validated target, and a proprietary
  detection technology then screens large drug-like compound libraries for binders that displace the probe, yielding allosteric
  inhibitors, localization modulators and molecular glues without iterative structural biology. Its internal pipeline focuses
  on phenylketonuria (PKU) — where JNT-517, an oral inhibitor acting at a cryptic allosteric site on the SLC6A19 transporter,
  reached Phase 1b/2 — and on immune-mediated diseases including targets such as interferon regulatory factor 3 (IRF3), alongside
  biopharma collaborations that include Roche. Otsuka Pharmaceutical Co., Ltd. completed its acquisition of Jnana on 23 September
  2024 for $800 million plus up to $325 million in development and regulatory milestones, making Jnana a direct subsidiary
  of Otsuka America, Inc.; Otsuka initiated a global Phase 3 trial of repinatrabit in PKU in December 2025. Jnana Therapeutics
  runs no developer program and publishes no product API, developer portal, API reference or SDK. The only machine-readable
  surface reachable without credentials is the WordPress REST content API behind www.jnanatx.com, catalogued here.'
deliveryModel:
  model: saas
  open_source: false
  commercial: true
  callable_host: true
  label: Hosted service · you call their endpoint
  confidence: high
  source:
  - openapi
  - pricing
  generated: '2026-08-28'
  method: derived
accessModel:
  pricing: unknown
  onboarding: unknown
  trial: false
  try_now: false
  public: false
  label: Unknown
  confidence: low
  source:
  - authentication
  - rate-limits
  - security
  generated: '2026-09-03'
  method: derived
image: https://www.jnanatx.com/wp-content/uploads/2022/09/cropped-android-chrome-512x512-1.png
url: https://raw.githubusercontent.com/api-evangelist/jnana-therapeutics/refs/heads/main/apis.yml
x-type: company
x-source: harvest:secondary-market
x-tier: profiled
x-tier-reason: enriched
specificationVersion: '0.23'
created: '2026-08-23'
modified: '2026-08-23'
tags:
- Company
- Biotechnology
- Pharmaceuticals
- Drug Discovery
- chemoproteomics
- Rare Disease
- Immunology
- Life Sciences
- Clinical Trials
- content-api
tags_raw:
- Company
- biotechnology
- pharmaceuticals
- drug-discovery
- chemoproteomics
- rare-disease
- immunology
- life-sciences
- clinical-trials
- content-api
apis:
- aid: jnana-therapeutics:jnanatx-com-website-wordpress-rest
  name: Jnana Therapeutics Website (WordPress REST)
  description: 'The public WordPress REST API (wp-json) of the Jnana Therapeutics website at www.jnanatx.com: the route index
    of the site''s content management system, catalogued as one site surface rather than as separate APIs.'
  baseURL: https://www.jnanatx.com/wp-json
  tags:
  - WordPress
  x-surface: platform-generated
  properties:
  - type: Documentation
    url: https://www.jnanatx.com/wp-json
  x-platform: wordpress
  x-platform-surface: rest
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: DomainSecurity
  url: security/jnana-therapeutics-domain-security.yml
- type: Website
  url: https://www.jnanatx.com/
- type: Platform
  url: https://www.jnanatx.com/rapid-platform/
- type: Programs
  url: https://www.jnanatx.com/programs/
- type: Team
  url: https://www.jnanatx.com/team/
- type: News
  url: https://www.jnanatx.com/news/
- type: BlogRSS
  url: https://www.jnanatx.com/feed/
- type: Careers
  url: https://www.jnanatx.com/join-us/
- type: ContactUs
  url: https://www.jnanatx.com/contact-us/
- type: PrivacyPolicy
  url: https://www.jnanatx.com/privacy-policy/
- type: TermsOfService
  url: https://www.jnanatx.com/terms-of-use/
- type: LinkedIn
  url: https://www.linkedin.com/company/jnana-therapeutics/
- type: X
  url: https://x.com/jnanatx
- type: ParentCompany
  url: https://www.otsuka.co.jp/en/
- type: SecondaryMarket
  url: https://forgeglobal.com/jnana-therapeutics_stock/
- type: Authentication
  url: authentication/jnana-therapeutics-authentication.yml
- type: Conventions
  url: conventions/jnana-therapeutics-conventions.yml
- type: Conformance
  url: conformance/jnana-therapeutics-conformance.yml
- type: ErrorCatalog
  url: errors/jnana-therapeutics-problem-types.yml
- type: Lifecycle
  url: lifecycle/jnana-therapeutics-lifecycle.yml
- type: DataModel
  url: data-model/jnana-therapeutics-data-model.yml
- type: Packages
  url: packages/jnana-therapeutics-packages.yml
- type: RateLimits
  url: rate-limits/jnana-therapeutics-rate-limits.yml
- type: Plans
  url: plans/jnana-therapeutics-plans-pricing.yml
- type: LLMsTxt
  url: llms/jnana-therapeutics-llms.txt
- type: AgentSkill
  url: skills/_index.yml
x-enrichment:
  date: '2026-08-23'
  status: enriched
  artifacts_added: 18
  pass: local-v1