iECURE is a clinical-stage genetic medicines company developing variant-agnostic, in vivo targeted gene insertion therapies for rare, life-threatening inherited metabolic diseases, with an initial focus on urea cycle disorders and other neurometabolic conditions of the liver. The company takes its name from iecur, the Latin word for liver, and was founded on the translational gene therapy research of James M. Wilson, M.D., Ph.D., advancing its pipeline in partnership with the University of Pennsylvania Gene Therapy Program. Its lead candidate, ECUR-506, pairs a dual-AAV delivery approach with Precision BioSciences' ARCUS nuclease to insert a functional copy of the OTC gene into the genome of infants with neonatal-onset ornithine transcarbamylase deficiency; it is in the OTC-HOPE study and has received FDA Orphan Drug, Rare Pediatric Disease, Fast Track and RMAT designations plus EU orphan designation, with clinical trial clearances in the United States, United Kingdom, Australia and the EU. Discovery-stage programs target citrullinemia type 1 and phenylketonuria. iECURE has raised roughly $115 million across a $50 million Series A in 2021 and a $65 million Series A-1 in 2022 from Versant Ventures, OrbiMed, Novo Holdings, the Qatar Investment Authority, LYFE Capital and Double Point Ventures. iECURE runs no developer program and publishes no product API, developer portal or API documentation. The only machine-readable surface reachable without credentials is the WordPress REST content API behind iecure.com, catalogued here.
iECURE publishes 10 APIs on the APIs.io network, including Discovery API, Posts API, Pages API, and 7 more. Tagged areas include Company, Biotechnology, Genetic Medicine, Gene Editing, and Gene Therapy.
iECURE’s developer surface includes product news, support, authentication, and 25 more developer resources.
Regulatory Posture applies to this provider. Its tags matched the
Health regime, so
Regulatory Posture carries 15 points of the composite.
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Create-or-Update Ergonomics does not apply to this provider. The published contracts declare
no write operations, and a read-only API cannot create-or-update. The facet is excluded from this provider's
denominator entirely — not scored zero. A reference or data API is not deficient for being unable to
upsert.
The six quality facets above are damped to 85 points between them,
because the conditional facet above carries the other
15. That is why each facet's contribution is shown against a damped
maximum: raising a quality facet moves the composite by 85% of its nominal
weight, not 100%. The full arithmetic is at apis.io/rating/.
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Route, content-type, taxonomy and status discovery documents for the iECURE WordPress REST deployment. Ten namespaces and 351 routes are registered; only these discovery documen...
The iECURE news archive - press releases, media coverage, awards and scientific publications/presentations. 60 published posts at harvest time across six categories.
Categories and tags. Six news categories are registered (news, press release, in the news, awards, pubs & pres, Uncategorized); the post_tag taxonomy is registered but empty.
The `portfolio` custom post type as deployed by iECURE, which carries team members rather than portfolio work - 35 items at harvest time, classified by the portfolio_entries tax...
Author directory. Anonymously readable on this deployment - unusually, since most WordPress sites gate it - returning the two accounts that have published content.
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