Circle Pharma

aid: circle-pharma
name: Circle Pharma
description: 'Circle Pharma is a clinical-stage biopharmaceutical company in South San Francisco, California, developing cell-permeable,
  orally bioavailable macrocycle therapies for cancer. Founded in 2013 by Matthew P. Jacobson and Scott Lokey out of work
  on predicting synthetic macrocycle cell permeability, the company applies its proprietary MXMO structure-based design platform
  to protein-protein interactions that conventional small molecules cannot reach. Its pipeline targets cyclins, the regulators
  of the cell cycle that drive many cancers: lead program CID-078, a first-in-class oral cyclin A/B RxL inhibitor, is in Phase
  1 for advanced solid tumors, followed by a preclinical cyclin D1 RxL inhibitor and undisclosed cyclin programs partnered
  with Boehringer Ingelheim. Circle Pharma closed a $90M Series D led by The Column Group in 2024 and has an agreement with
  Eli Lilly to use Lilly TuneLab to strengthen the AI/ML side of the MXMO platform. Circle Pharma runs no developer program
  and publishes no product API; the only machine-readable surface it exposes is the anonymously readable WordPress REST content
  API behind circlepharma.com.'
image: https://circlepharma.com/wp-content/uploads/2024/01/Asset-2@2x.png
url: https://raw.githubusercontent.com/api-evangelist/circle-pharma/refs/heads/main/apis.yml
x-type: company
x-source: harvest:secondary-market
x-tier: profiled
x-tier-reason: enriched
specificationVersion: '0.20'
created: '2026-08-01'
modified: '2026-08-01'
tags:
- Company
- biotechnology
- pharmaceuticals
- oncology
- drug-discovery
- macrocycles
- clinical-trials
- life-sciences
- content-api
apis:
- aid: circle-pharma:circle-pharma-content-api
  name: Circle Pharma Content API
  description: The anonymously readable WordPress REST API behind circlepharma.com. It exposes Circle Pharma press releases,
    publications and in-the-news items (posts), site pages, the media library, the leadership and board roster (team + member_type
    taxonomy), the events calendar (all_events + event_type taxonomy) and cross-content search. This is not a developer product
    Circle Pharma markets; it is the site's own discovery surface, published at /wp-json/ and verified to return data without
    credentials. The OpenAPI in this repo is derived from that published route index.
  humanURL: https://developer.wordpress.org/rest-api/
  baseURL: https://circlepharma.com/wp-json
  tags:
  - content
  - press-releases
  - events
  - wordpress
  properties:
  - type: OpenAPI
    url: openapi/circle-pharma-content-openapi.yml
  - type: Overlay
    url: overlays/circle-pharma-content-overlay.yaml
  - type: Authentication
    url: authentication/circle-pharma-authentication.yml
  - type: ErrorCatalog
    url: errors/circle-pharma-problem-types.yml
  - type: Conventions
    url: conventions/circle-pharma-conventions.yml
  - type: DataModel
    url: data-model/circle-pharma-data-model.yml
  x-contract-provenance: Derived by the API Evangelist enrichment pipeline from the WordPress REST route index the site publishes
    at https://circlepharma.com/wp-json/ and verified against live anonymous responses on 2026-08-01. Circle Pharma publishes
    no developer documentation, no API reference and no support channel for this surface, so no Documentation/APIReference/GettingStarted
    pointers are emitted — the humanURL above is the upstream WordPress REST handbook that describes the wp/v2 contract.
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: Website
  url: https://circlepharma.com/
- type: About
  url: https://circlepharma.com/about-us
- type: Blog
  url: https://circlepharma.com/whats-new
- type: BlogRSS
  url: https://circlepharma.com/feed/
- type: PressReleases
  url: https://circlepharma.com/press-releases
- type: Publications
  url: https://circlepharma.com/publications
- type: Events
  url: https://circlepharma.com/upcoming-events
- type: Careers
  url: https://circlepharma.com/work-with-us
- type: Contact
  url: https://circlepharma.com/contact-us
- type: Investors
  url: https://circlepharma.com/investors
- type: Support
  url: https://circlepharma.com/contact-us
- type: TermsOfService
  url: https://circlepharma.com/terms-of-use
- type: PrivacyPolicy
  url: https://circlepharma.com/privacy-policy
- type: LinkedIn
  url: https://www.linkedin.com/company/circle-pharma-inc-/
- type: SecondaryMarket
  url: https://forgeglobal.com/circle-pharma_stock/
- type: Authentication
  url: authentication/circle-pharma-authentication.yml
- type: Conventions
  url: conventions/circle-pharma-conventions.yml
- type: Conformance
  url: conformance/circle-pharma-conformance.yml
- type: ErrorCatalog
  url: errors/circle-pharma-problem-types.yml
- type: Lifecycle
  url: lifecycle/circle-pharma-lifecycle.yml
- type: DataModel
  url: data-model/circle-pharma-data-model.yml
- type: WellKnown
  url: well-known/circle-pharma-well-known.yml
- type: DomainSecurity
  url: security/circle-pharma-domain-security.yml
- type: LLMsTxt
  url: llms/circle-pharma-llms.txt
- type: AgentSkill
  url: skills/_index.yml
x-enrichment:
  date: '2026-08-01'
  status: enriched
  artifacts_added: 15
  pass: local-v1