Castle Creek Biosciences

Castle Creek Biosciences is a late‑stage biotechnology company developing autologous fibroblast‑based gene therapies for rare genetic skin disorders such as dystrophic epidermolysis bullosa. The firm conducts a registrational trial of its lead candidate D‑Fi and aims to create transformative, personalized treatments for patients with severe genetic diseases. It operates from Exton, Pennsylvania, and focuses on both ex vivo and in vivo approaches to deliver durable therapeutic outcomes.

Castle Creek Biosciences is profiled on the APIs.io network. Tagged areas include Biotechnology, Gene Therapy, Regenerative Medicine, Healthcare, and Biotech Company.

Castle Creek Biosciences’ developer surface includes documentation and 11 more developer resources.

🌐 Visit website 📡 Source on GitHub

13.0/100 emerging Agent 3/100 human only Full breakdown ↓
scored 2026-10-09 · rubric v0.23.0

0 APIs

Biotechnology Gene Therapy Regenerative Medicine HealthcareBiotech Company

Kin Score

Kin Score How this is scored →
scored 2026-10-09 · rubric v0.23.0

Composite quality — 13.0/100 · emerging

Contract Quality 0.0 / 21

Developer Ergonomics 1.6 / 17

Access Clarity 3.6 / 17

Operational Transparency 1.2 / 11

Contract Governance 0.0 / 10

Discoverability 4.3 / 9

Regulatory Posture 2.3 / 15

Agent readiness — 3/100 · human only

Machine-Readable Contract 0 / 18

Agentic Access Contract 0 / 10

Documented Reversibility 0 / 6

MCP Server 12 / 12

Machine-Readable Auth 0 / 10

Idempotency 0 / 9

Stable Error Semantics 0 / 8

Request/Response Examples 0 / 7

Rate-Limit Signaling 0 / 7

Typed Event Surface 0 / 6

Agent Skills 0 / 5

Well-Known Catalog 0 / 4

Consent & Bot Identity 0 / 3

A2A Agent Card 0 / 8

Dry-Run / Simulate Mode 0 / 4

Delegated User Identity 0 / 6

Protected Resource Metadata 0 / 5

Registration Without a Human 0 / 6

Agentic Commerce Well-Known Document 0 / 5

Regulatory Posture applies to this provider. Its tags matched the Health regime, so Regulatory Posture carries 15 points of the composite. If this regime is wrong for your business, say so on your provider repo — the applicability map is public and we will correct it.

Create-or-Update Ergonomics could not be measured. We hold no machine-readable contract for this provider to read, so there is nothing to measure a write surface against. Excluded rather than scored zero: never-measured and measured-empty are different facts. Publishing an OpenAPI is what makes this facet — and several others — scorable at all.

The six quality facets above are damped to 85 points between them, because the conditional facet above carries the other 15. That is why each facet's contribution is shown against a damped maximum: raising a quality facet moves the composite by 85% of its nominal weight, not 100%. The full arithmetic is at apis.io/rating/.

Improve this rating by publishing the missing artifacts — every area above can be raised, and the full rubric is at apis.io/rating/. Every facet and dimension name above is a link: it opens that measurement's own page — what it means, the exact checks that feed it, how the whole catalog distributes on it, and the providers at the top of it. This rating is computed from github.com/api-evangelist/castle-creek-biosciences: open an issue to ask a question, or submit a pull request to add artifacts. Submit an artifact on GitHub — free → Manage your own listing — the Influence plan, $499/mo →

Security Posture 2

Authentication, domain security, vulnerability disclosure, and trust-center signals.

Castle Creek Biosciences Domain Security

TLSv1.3 · HSTS · DNSSEC · DMARC

SECURITY

Castle Creek Biosciences Vulnerability Disclosure

security.txt · contact published

SECURITY

Resources

Documentation 1

Reference material describing how the API behaves

Documentation

Documentation

Agent Surfaces 1

MCP servers, agent skills, and machine-readable catalogs

WellKnown

WellKnown

Access & Security 4

Authentication, authorization, and security posture

SecurityTxt

SecurityTxt

Security

Security

VulnerabilityDisclosure

VulnerabilityDisclosure

DomainSecurity

DomainSecurity

Commercial 2

Pricing, plans, and the legal terms of use

PrivacyPolicy

PrivacyPolicy

TermsOfService

TermsOfService

Company 1

The organization behind the API

Website

Website

Other 3

Properties that don't map to a standard resource type

Hosts

Hosts

Vendors

Vendors

Leadership

Leadership

Source (apis.yml)

aid: castle-creek-biosciences
name: Castle Creek Biosciences
image: http://castlecreekbio.com/wp-content/uploads/2020/03/CCB-Logo-500x500-1.png
description: Castle Creek Biosciences is a late‑stage biotechnology company developing autologous fibroblast‑based gene therapies
  for rare genetic skin disorders such as dystrophic epidermolysis bullosa. The firm conducts a registrational trial of its
  lead candidate D‑Fi and aims to create transformative, personalized treatments for patients with severe genetic diseases.
  It operates from Exton, Pennsylvania, and focuses on both ex vivo and in vivo approaches to deliver durable therapeutic
  outcomes.
url: https://raw.githubusercontent.com/api-evangelist/castle-creek-biosciences/refs/heads/main/apis.yml
x-type: company
x-source: harvest:secondary-market
x-tier: profiled
x-tier-reason: enrichment pass 2026-10-07 (modular-v1; was harvest)
specificationVersion: '0.20'
created: '2026-10-07'
modified: '2026-10-07'
tags:
- Biotechnology
- Gene Therapy
- Regenerative Medicine
- Healthcare
- Biotech Company
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: SecurityTxt
  url: well-known/castle-creek-biosciences-clarity-security.txt
- type: WellKnown
  url: well-known/castle-creek-biosciences-well-known.yml
- type: Security
  url: https://clarity.com/vdp
- type: Hosts
  url: hosts/castle-creek-biosciences-hosts.yml
- type: Vendors
  url: vendors/castle-creek-biosciences-vendors.yml
- type: Leadership
  url: https://castlecreekbio.com/about/leadership/
- type: VulnerabilityDisclosure
  url: security/castle-creek-biosciences-vulnerability-disclosure.yml
- type: DomainSecurity
  url: security/castle-creek-biosciences-domain-security.yml
- type: Website
  url: https://castlecreekbio.com
- type: Documentation
  url: https://castlecreekbio.com/technology/
- type: PrivacyPolicy
  url: https://castlecreekbio.com/privacy-policy
- type: TermsOfService
  url: https://castlecreekbio.com/terms-of-use
apis: []
x-coverage:
  state: none
  reason: no-developer-program
  method: derived
  generated: '2026-10-07'
  generator: derive-coverage.py (pre-flight evidence)
  detail: the company publishes no developer documentation host and no machine-readable contract on its own domain
  evidence:
  - url: https://castlecreekbio.com
    status: 200
  - url: https://www.hiive.com/securities/castle-creek-biosciences-stock
    status: 200
x-enrichment:
  date: '2026-10-07'
  status: enriched
  artifacts_added: 7
  pass: modular-v1
  engine: identity=local,contract=local,surfaces=local,docs=local,regulatory=local

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