Bota Biosciences
Bota Biosciences (Bota Bio, 恩和科技) is an industrial and synthetic biology company that applies AI-driven computation and laboratory automation to bio-manufacturing. Its in-house Bota Biofoundry and Cell2Cloud platforms combine computational algorithms, non-model industrial strain engineering, rapid iterative enzyme engineering and performance protein design to shorten design-build-test-learn cycles, and in March 2026 it launched SAION AI, a three-layer "Physical AI" platform (cognition, orchestration, execution) that drives laboratory hardware through a proprietary Biological Protocol Language. Bota commercializes this work as physical ingredients rather than software: Purtect bio-preservatives (nisin, natamycin, ε-poly-lysine, lysozyme), Prorylia biomimetic proteins and Re² Coffea Arabica peptides, sold through its HeliaGenesis food and nutrition brand and its YuccaElements personal care brand, with partnerships including BASF, Proya, Syensqo and Puratos. Founded in 2019 with operations in Hangzhou, China and the San Francisco Bay Area, Bota publishes no developer portal, no public API documentation, no SDKs and no machine-readable specification; its computational software is internal laboratory tooling and its SAION AI application is reachable only through a login with an administrator-managed account whitelist.
Bota Biosciences is profiled on the APIs.io network. Tagged areas include Company, Biotechnology, Synthetic Biology, Biomanufacturing, and Industrial Biotechnology.
Bota Biosciences’ developer surface includes engineering blog and 12 more developer resources.
0 APIs
Authentication, domain security, vulnerability disclosure, and trust-center signals.
aid: bota-biosciences
name: Bota Biosciences
description: 'Bota Biosciences (Bota Bio, 恩和科技) is an industrial and synthetic biology company that applies AI-driven computation
and laboratory automation to bio-manufacturing. Its in-house Bota Biofoundry and Cell2Cloud platforms combine computational
algorithms, non-model industrial strain engineering, rapid iterative enzyme engineering and performance protein design to
shorten design-build-test-learn cycles, and in March 2026 it launched SAION AI, a three-layer "Physical AI" platform (cognition,
orchestration, execution) that drives laboratory hardware through a proprietary Biological Protocol Language. Bota commercializes
this work as physical ingredients rather than software: Purtect bio-preservatives (nisin, natamycin, ε-poly-lysine, lysozyme),
Prorylia biomimetic proteins and Re² Coffea Arabica peptides, sold through its HeliaGenesis food and nutrition brand and
its YuccaElements personal care brand, with partnerships including BASF, Proya, Syensqo and Puratos. Founded in 2019 with
operations in Hangzhou, China and the San Francisco Bay Area, Bota publishes no developer portal, no public API documentation,
no SDKs and no machine-readable specification; its computational software is internal laboratory tooling and its SAION AI
application is reachable only through a login with an administrator-managed account whitelist.'
url: https://raw.githubusercontent.com/api-evangelist/bota-biosciences/refs/heads/main/apis.yml
x-type: company
x-source: harvest:secondary-market
x-tier: profiled
x-tier-reason: enriched
deliveryModel:
model: unknown
open_source: false
commercial: false
callable_host: false
label: Delivery model not determined — needs a product licence on record
confidence: low
source:
- none
generated: '2026-08-28'
method: derived
accessModel:
pricing: unknown
onboarding: unknown
trial: false
try_now: false
public: false
label: Unknown
confidence: low
source:
- security
generated: '2026-09-02'
method: derived
specificationVersion: '0.23'
created: '2026-08-08'
modified: '2026-08-08'
image: https://bota.bio/wp-content/uploads/2024/08/bota-logo.png
tags:
- Company
- Biotechnology
- Synthetic Biology
- Biomanufacturing
- Industrial Biotechnology
- Enzyme Engineering
- Ingredients
- Food and Nutrition
- Personal Care
- Artificial Intelligence
- China
tags_raw:
- Company
- Biotechnology
- Synthetic Biology
- Bio-Manufacturing
- Industrial Biotechnology
- Enzyme Engineering
- Ingredients
- Food and Nutrition
- Personal Care
- Artificial Intelligence
- China
apis: []
maintainers:
- FN: Kin Lane
email: kin@apievangelist.com
- FN: APIs.json
email: info@apis.io
common:
- type: DomainSecurity
url: security/bota-biosciences-domain-security.yml
- type: Website
url: https://bota.bio/
- type: About
url: https://bota.bio/about-bota/
- type: Technology
url: https://bota.bio/bota-biofoundry/
- type: Product
url: https://bota.bio/performance-protein-solutions/
- type: Brand
url: https://www.heliagenesis.com/
- type: Brand
url: https://www.yuccaelements.com/
- type: Contact
url: https://bota.bio/contact/
- type: Blog
url: https://bota.bio/bota-news/
- type: BlogRSS
url: https://bota.bio/feed/
- type: LinkedIn
url: https://www.linkedin.com/company/botabio
- type: SecondaryMarket
url: https://www.hiive.com/securities/bota-biosciences-stock
- type: LLMsTxt
url: llms/bota-biosciences-llms.txt
x-enrichment:
date: '2026-08-08'
status: minimal
artifacts_added: 3
pass: local-v1
contract_discovery:
openapi: not-published
swagger: none
graphql: none
asyncapi: none
mcp: none
agent_card: none
note: 'Full STEP 0b contract discovery run 2026-08-08 across every host Bota publishes: bota.bio (the corporate site),
www.heliagenesis.com and www.yuccaelements.com (the two product brands), saion.ai / saionai.com (the SAION AI platform),
and the assets-internal-prod.bota.bio release CDN. On bota.bio and both brand sites, /llms.txt, /openapi.json, /openapi.yaml,
/swagger.json, /api-docs, /redoc, /graphql, /.well-known/security.txt, /.well-known/openid-configuration, /.well-known/oauth-authorization-server,
/.well-known/api-catalog, /.well-known/ai-plugin.json, /.well-known/agent-card.json and /.well-known/agent.json all
return 404. The complete Yoast sitemap for bota.bio is 19 pages — technology, solutions, products, about, news and contact,
in English and Chinese — with no developer, docs or API section. No GitHub organization exists (botabio, bota-bio and
BotaBiosciences all 404 on the GitHub API, and an org search for "bota bio" returns zero results). The only machine-readable
surface bota.bio serves is the stock WordPress REST API at /wp-json/ (265 routes across wp/v2 and plugin namespaces
such as yoast/v1, wordfence/v1 and forminator/v1) — CMS plumbing, not a product API, and deliberately not registered
as one.'
saion_note: 'SAION AI (saion.ai, confirmed as Bota''s by its assets-internal-prod.bota.bio asset base and bota-logo.svg)
is a Flutter/CanvasKit single-page application, release 1.3.90 built 2026-08-07, that renders its entire interface to
a WebGL canvas — the served HTML carries no readable content at all. Its route catch-all answers HTTP 200 with the same
SPA shell for every path probed, including /openapi.json, /swagger.json, /graphql, /mcp and every /.well-known/* path;
a control-path diff against /zzz-definitely-not-a-real-path-9f8a7b returned a byte-identical-length shell, so none of
those 200s is a real document. saion.ai/robots.txt is genuine and carries a Cloudflare-managed content-signals policy
(Content-Signal: search=yes, ai-train=no, use=reference) plus explicit Disallow rules for ClaudeBot, GPTBot, CCBot,
Google-Extended, Bytespider, Amazonbot, Applebot-Extended and meta-externalagent; User-agent * is Allow: /. Access to
the application itself is login-gated, and the backend carries an administrator-managed email/domain whitelist, so there
is no self-serve developer access.'
not_harvested: 'A complete OpenAPI 3.1.0 document for the SAION backend (title "Saion API", 346 paths, 395 operations,
521 schemas, FastAPI-generated) is anonymously fetchable, together with a live Swagger UI and ReDoc, on a host Bota
names "internal-api". It was deliberately NOT harvested into openapi/, NOT wired as a type: OpenAPI pointer, and its
endpoints are not enumerated in any public artifact in this repository. Bota publishes no developer program, no API
reference and no signup for API access: this contract is exposed, not published, and scoring it would credit Bota with
a developer surface it never offered while republishing an internal contract that includes its full administrative endpoint
inventory. The API itself is properly protected — the spec declares a global BearerAuth requirement and 376 of 395 operations
carry an explicit security requirement — so this is an exposure of the contract document, not of data, and no protected
endpoint was called. Bota also publishes no security.txt and no vulnerability-disclosure channel on any of its hosts,
so there is no route to report this to them automatically; it is flagged here for a human to disclose directly. Re-runs
must not "fix" this by harvesting the spec.'
x-coverage:
state: gated
reason: customer-only-docs
detail: Bota's only software product, the SAION AI platform at saion.ai, is a Flutter canvas application behind a login
whose backend enforces an administrator-managed email and domain whitelist, so no reference, spec or signup is reachable
without an approved account — saion.ai/openapi.json answers 200 but returns the same single-page-app shell as a nonsense
control path, not a specification — while the corporate site bota.bio publishes marketing and news pages only.
evidence:
- url: https://bota.bio/openapi.json
status: 404
- url: https://bota.bio/.well-known/agent-card.json
status: 404
- url: https://saion.ai/openapi.json
status: 200
- url: https://saion.ai/robots.txt
status: 200
- url: https://api.github.com/orgs/botabio
status: 404
checked: '2026-08-08'
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