BillionToOne website screenshot

BillionToOne

BillionToOne is a molecular diagnostics company using proprietary single-molecule Quantitative Counting Template (QCT) technology to detect disease at the DNA level from cell-free DNA. Its Unity prenatal screening suite (Unity Complete, Unity Confirm, and Unity fetal antigen tests) delivers non-invasive prenatal testing from maternal blood at nine weeks, and its Northstar oncology line (Northstar Select and Northstar Response) provides liquid-biopsy therapy selection and real-time treatment-response monitoring. BillionToOne integrates with electronic medical records through a collaboration with Epic and delivers results through its provider and patient portals. It was added to the API Evangelist network as a portfolio company of 500 Global, Norwest Venture Partners, and Y Combinator.

BillionToOne is profiled on the APIs.io network. Tagged areas include Company, Molecular Diagnostics, Healthcare, Genomics, and Prenatal Testing.

BillionToOne’s developer surface includes support, engineering blog, and 6 more developer resources.

🌐 Visit website 📡 Source on GitHub
19.3/100 emerging ▬ flat Agent 0/100 human only Full breakdown ↓
scored 2026-07-27 · rubric v0.5
0 APIs
CompanyMolecular DiagnosticsHealthcareGenomicsPrenatal TestingOncologyLiquid BiopsyDiagnostics

Kin Score

Kin Score Kin Score How this is scored →
scored 2026-07-27 · rubric v0.5
Composite quality — 19.3/100 · emerging
Contract Quality 0.0 / 25
Developer Ergonomics 1.3 / 20
Commercial Clarity 7.4 / 20
Operational Transparency 0.0 / 13
Governance 0.0 / 12
Discoverability 6.8 / 10
Agent readiness — 0/100 · human only
Machine-Readable Contract 0 / 18
Agentic Access Contract 0 / 15
MCP Server 0 / 12
Machine-Readable Auth 0 / 10
Idempotency 0 / 9
Stable Error Semantics 0 / 8
Request/Response Examples 0 / 7
Rate-Limit Signaling 0 / 7
Typed Event Surface 0 / 6
Agent Skills 0 / 5
Well-Known Catalog 0 / 4
Consent & Bot Identity 0 / 3
Improve this rating by publishing the missing artifacts — every area above can be raised, and the full rubric is at apis.io/rating/. This rating is computed from github.com/api-evangelist/billiontoone: open an issue to ask a question, or submit a pull request to add artifacts. Want it done for you? Prioritized profiling — $2,500 →

Security Posture 2

Authentication, domain security, vulnerability disclosure, and trust-center signals.

Billiontoone Domain Security

TLSv1.3 · DMARC

SECURITY

Billiontoone Trust Center

SOC 2, HIPAA

SECURITY

Resources

Access & Security 3

Authentication, authorization, and security posture

TrustCenter
TrustCenter
 Compliance
Compliance
 DomainSecurity
DomainSecurity

Operate 1

Status, limits, changes, and where to get help

Support
Support

Commercial 2

Pricing, plans, and the legal terms of use

PrivacyPolicy
PrivacyPolicy
 TermsOfService
TermsOfService

Company 2

The organization behind the API

Website
Website
 Blog
Blog

Source (apis.yml)

apis.yml Raw ↑ 
aid: billiontoone
name: BillionToOne
description: BillionToOne is a molecular diagnostics company using proprietary single-molecule Quantitative Counting Template
  (QCT) technology to detect disease at the DNA level from cell-free DNA. Its Unity prenatal screening suite (Unity Complete,
  Unity Confirm, and Unity fetal antigen tests) delivers non-invasive prenatal testing from maternal blood at nine weeks,
  and its Northstar oncology line (Northstar Select and Northstar Response) provides liquid-biopsy therapy selection and real-time
  treatment-response monitoring. BillionToOne integrates with electronic medical records through a collaboration with Epic
  and delivers results through its provider and patient portals. It was added to the API Evangelist network as a portfolio
  company of 500 Global, Norwest Venture Partners, and Y Combinator.
url: https://raw.githubusercontent.com/api-evangelist/billiontoone/refs/heads/main/apis.yml
x-type: company
x-source: vc-portfolio
x-backed-by:
- 500-global
- norwest-venture-partners
- y-combinator
x-tier: stub
x-tier-reason: portfolio-lead
accessModel:
  pricing: unknown
  onboarding: unknown
  trial: false
  try_now: false
  public: false
  label: Unknown
  confidence: low
  source: []
  generated: '2026-07-22'
  method: derived
specificationVersion: '0.20'
created: '2026-07-17'
modified: '2026-07-18'
image: https://cdn.prod.website-files.com/6880c9300eb95bb084b75b2e/68f9c805125d5bd39b931a16_bto_logo_new.svg
tags:
- Company
- Molecular Diagnostics
- Healthcare
- Genomics
- Prenatal Testing
- Oncology
- Liquid Biopsy
- Diagnostics
apis: []
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: TrustCenter
  url: security/billiontoone-trust-center.yml
- type: Compliance
  url: https://trust.billiontoone.com/
- type: DomainSecurity
  url: security/billiontoone-domain-security.yml
- type: Website
  url: https://billiontoone.com
- type: Support
  url: https://billiontoone.com/contact
- type: Blog
  url: https://www.billiontoone.com/news-media
- type: PrivacyPolicy
  url: https://billiontoone.com/privacy-policy
- type: TermsOfService
  url: https://billiontoone.com/terms-of-use
x-enrichment:
  date: '2026-07-19'
  status: backfilled
  pass: local-v1
  note: backfilled from .gitignore signal + verified work evidence