Applied Cognition website screenshot

Applied Cognition

Applied Cognition is a clinical-stage neuroscience company unlocking the therapeutic power of the brain's glymphatic system, the waste-clearance mechanism implicated in neurodegeneration. The company pairs a first-in-human, non-invasive platform for continuous, real-time measurement of glymphatic function (validated against contrast-enhanced MRI) with a small-molecule drug pipeline targeting Alzheimer's disease, Parkinson's disease, and post-traumatic headache, supported by issued platform patents and datasets positioned for AI integration. Backed by Mayfield, it was surfaced as a portfolio-company lead and added to the API Evangelist network for enrichment. It is a therapeutics/medical company and does not currently publish a public developer program, API, or developer documentation.

Applied Cognition is profiled on the APIs.io network. Tagged areas include Company, Healthcare, Biotechnology, Neuroscience, and Therapeutics.

Applied Cognition’s developer surface includes product news, support, and 3 more developer resources.

🌐 Visit website 📡 Source on GitHub
8.4/100 minimal ▬ flat Agent 0/100 human only Full breakdown ↓
scored 2026-07-27 · rubric v0.5
0 APIs
CompanyHealthcareBiotechnologyNeuroscienceTherapeuticsGlymphaticDrug DiscoveryMedical

Kin Score

Kin Score Kin Score How this is scored →
scored 2026-07-27 · rubric v0.5
Composite quality — 8.4/100 · minimal
Contract Quality 0.0 / 25
Developer Ergonomics 0.9 / 20
Commercial Clarity 0.0 / 20
Operational Transparency 0.0 / 13
Governance 0.0 / 12
Discoverability 6.8 / 10
Agent readiness — 0/100 · human only
Machine-Readable Contract 0 / 18
Agentic Access Contract 0 / 15
MCP Server 0 / 12
Machine-Readable Auth 0 / 10
Idempotency 0 / 9
Stable Error Semantics 0 / 8
Request/Response Examples 0 / 7
Rate-Limit Signaling 0 / 7
Typed Event Surface 0 / 6
Agent Skills 0 / 5
Well-Known Catalog 0 / 4
Consent & Bot Identity 0 / 3
Improve this rating by publishing the missing artifacts — every area above can be raised, and the full rubric is at apis.io/rating/. This rating is computed from github.com/api-evangelist/applied-cognition: open an issue to ask a question, or submit a pull request to add artifacts. Want it done for you? Prioritized profiling — $2,500 →

Security Posture 1

Authentication, domain security, vulnerability disclosure, and trust-center signals.

Applied Cognition Domain Security

TLSv1.3 · DMARC

SECURITY

Resources

Access & Security 1

Authentication, authorization, and security posture

DomainSecurity
DomainSecurity

Operate 1

Status, limits, changes, and where to get help

Support
Support

Company 3

The organization behind the API

Website
Website
 About
About
 News
News

Source (apis.yml)

apis.yml Raw ↑ 
aid: applied-cognition
name: Applied Cognition
description: Applied Cognition is a clinical-stage neuroscience company unlocking the therapeutic power of the brain's glymphatic
  system, the waste-clearance mechanism implicated in neurodegeneration. The company pairs a first-in-human, non-invasive
  platform for continuous, real-time measurement of glymphatic function (validated against contrast-enhanced MRI) with a small-molecule
  drug pipeline targeting Alzheimer's disease, Parkinson's disease, and post-traumatic headache, supported by issued platform
  patents and datasets positioned for AI integration. Backed by Mayfield, it was surfaced as a portfolio-company lead and
  added to the API Evangelist network for enrichment. It is a therapeutics/medical company and does not currently publish
  a public developer program, API, or developer documentation.
url: https://raw.githubusercontent.com/api-evangelist/applied-cognition/refs/heads/main/apis.yml
accessModel:
  pricing: unknown
  onboarding: unknown
  trial: false
  try_now: false
  public: false
  label: Unknown
  confidence: low
  source: []
  generated: '2026-07-22'
  method: derived
image: https://appliedcognition.com/ac_logo_edited.png
x-type: company
x-source: vc-portfolio
x-backed-by:
- mayfield
x-tier: stub
x-tier-reason: portfolio-lead
x-industry: healthcare-biotech
x-has-public-api: false
specificationVersion: '0.20'
created: '2026-07-17'
modified: '2026-07-17'
tags:
- Company
- Healthcare
- Biotechnology
- Neuroscience
- Therapeutics
- Glymphatic
- Drug Discovery
- Medical
apis: []
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: Website
  url: https://appliedcognition.com
- type: About
  url: https://appliedcognition.com/about
- type: News
  url: https://appliedcognition.com/news
- type: Support
  url: https://appliedcognition.com/contact
- type: DomainSecurity
  url: security/applied-cognition-domain-security.yml
x-enrichment:
  date: '2026-07-19'
  status: backfilled
  pass: local-v1
  note: backfilled from .gitignore signal + verified work evidence