4D Molecular Therapeutics (4DMT)

4D Molecular Therapeutics (4DMT) is a late-stage clinical biotechnology company headquartered in Emeryville, California, developing genetic medicines for large-market diseases. The company uses a proprietary directed-evolution platform it calls Therapeutic Vector Evolution to invent customized, proprietary adeno-associated virus (AAV) gene delivery vectors that carry therapeutic payloads to specific tissue types. Its pipeline targets retinal and pulmonary disease, led by 4D-150 for wet age-related macular degeneration and diabetic macular edema, and 4D-710 for cystic fibrosis lung disease. 4DMT is a therapeutics developer rather than a software vendor: it publishes no public API, developer portal, SDK, or machine-readable API contract of any kind.

4D Molecular Therapeutics (4DMT) is profiled on the APIs.io network. Tagged areas include Company, Biotechnology, Gene Therapy, Genetic Medicine, and Life Sciences.

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9.6/100 minimal ▬ flat Agent 0/100 human only Front door AI 1/6 silent Heartbeat 100/100 alive Full breakdown ↓
scored 2026-11-06 · rubric v0.27.0 · Show this score on your site →

0 APIs

Company Biotechnology Gene Therapy Genetic Medicine Life Sciences Pharmaceuticals Clinical Trials Ophthalmology

Kin Score

Kin Score How this is scored →
scored 2026-11-06 · rubric v0.27.0

Composite quality — 9.6/100 · minimal

Contract Quality 0.0 / 21

Developer Ergonomics 0.0 / 17

Access Clarity 3.6 / 17

Operational Transparency 0.0 / 11

Contract Governance 0.0 / 10

Discoverability 4.7 / 9

Regulatory Posture 1.6 / 15

Agent readiness — 0/100 · human only

Machine-Readable Contract 0 / 18

Agentic Access Contract 0 / 10

Documented Reversibility 0 / 6

MCP Server 0 / 12

Machine-Readable Auth 0 / 10

Idempotency 0 / 9

Stable Error Semantics 0 / 8

Request/Response Examples 0 / 7

Rate-Limit Signaling 0 / 7

Typed Event Surface 0 / 6

Agent Skills 0 / 5

Well-Known Catalog 0 / 4

Consent & Bot Identity 0 / 3

A2A Agent Card 0 / 8

Dry-Run / Simulate Mode 0 / 4

Delegated User Identity 0 / 6

Protected Resource Metadata 0 / 5

Registration Without a Human 0 / 6

Agentic Commerce Well-Known Document 0 / 5

Pagination 5 / 5

Distinct Operations 3 / 3

MCP Tool Quality 6 / 6

Regulatory Posture applies to this provider. Its tags matched the Health regime, so Regulatory Posture carries 15 points of the composite. If this regime is wrong for your business, say so on your provider repo — the applicability map is public and we will correct it.

Create-or-Update Ergonomics could not be measured. We hold no machine-readable contract for this provider to read, so there is nothing to measure a write surface against. Excluded rather than scored zero: never-measured and measured-empty are different facts. Publishing an OpenAPI is what makes this facet — and several others — scorable at all.

The six quality facets above are damped to 85 points between them, because the conditional facet above carries the other 15. That is why each facet's contribution is shown against a damped maximum: raising a quality facet moves the composite by 85% of its nominal weight, not 100%. The full arithmetic is at apis.io/rating/.

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Agent readiness — checks not met, largest first (exact, from this profile):

Machine-Readable Contract +18 pts — api_specs includes an OpenAPI document
MCP Server +12 pts — deployment.mode + probe verdict on the mcp/ manifest, not the pointer; an unprobed slug falls back to authorship
Agentic Access Contract +10 pts — agentic_access artifact present (x-agentic-access), graded by author
Machine-Readable Auth +10 pts — a served openid-configuration/oauth-authorization-server carrying `issuer` (served), else the securitySchemes class in the provider OpenAPIs — bound (mutualTLS, DPoP, Signature) > negotiable (oauth2 authorizationCode/clientCredentials, openIdConnect) > bearer (http bearer, apiKey)
Idempotency +9 pts — OpenAPI mutating operations declare an idempotency key — a header, a request-body property, or a named de-duplication token whose own description says so (verified); else common[].type matches /idempoten/i (documented)
Stable Error Semantics +8 pts — OpenAPI $refs a shared error schema across 4xx/5xx responses (verified), else common[].type includes ErrorCatalog / ErrorCodes / DeclineCodes

13 more unmet checks in the Agent Readiness table above.

Kin Score — facets with the most composite points still available (weight × headroom):

Contract Quality scores 0.0 — up to +25.0 composite points
Developer Ergonomics scores 0.0 — up to +20.0 composite points
Access Clarity scores 21.1 — up to +15.8 composite points

Each check links to what satisfies it. Publish the artifact, or tell us where it already lives, and the score moves on the next scoring run.

Improve this rating by publishing the missing artifacts — every area above can be raised, and the full rubric is at apis.io/rating/. Every facet and dimension name above is a link: it opens that measurement's own page — what it means, the exact checks that feed it, how the whole catalog distributes on it, and the providers at the top of it. This rating is computed from the provider profile at artifacts.apis.io/4d-molecular-therapeutics-4dmt/apis.yml: open an issue on github.com/api-evangelist/4d-molecular-therapeutics-4dmt to ask a question or point us at an artifact you publish. Submit an artifact on GitHub — free → Manage your own listing — the Influence plan, $499/mo →

Security Posture 1

Authentication, domain security, vulnerability disclosure, and trust-center signals.

4D Molecular Therapeutics 4Dmt Domain Security

TLSv1.3 · DMARC

SECURITY

Resources

Agent Surfaces 1

MCP servers, agent skills, and machine-readable catalogs

LLMsTxt

LLMsTxt

Access & Security 1

Authentication, authorization, and security posture

DomainSecurity

DomainSecurity

Commercial 2

Pricing, plans, and the legal terms of use

TermsOfService

TermsOfService

PrivacyPolicy

PrivacyPolicy

Company 1

The organization behind the API

Website

Website

Source (apis.yml)

aid: 4d-molecular-therapeutics-4dmt
name: 4D Molecular Therapeutics (4DMT)
description: '4D Molecular Therapeutics (4DMT) is a late-stage clinical biotechnology company headquartered in Emeryville,
  California, developing genetic medicines for large-market diseases. The company uses a proprietary directed-evolution platform
  it calls Therapeutic Vector Evolution to invent customized, proprietary adeno-associated virus (AAV) gene delivery vectors
  that carry therapeutic payloads to specific tissue types. Its pipeline targets retinal and pulmonary disease, led by 4D-150
  for wet age-related macular degeneration and diabetic macular edema, and 4D-710 for cystic fibrosis lung disease. 4DMT is
  a therapeutics developer rather than a software vendor: it publishes no public API, developer portal, SDK, or machine-readable
  API contract of any kind.'
accessModel:
  pricing: unknown
  onboarding: unknown
  trial: false
  try_now: false
  public: false
  label: Unknown
  confidence: low
  probe_state: none
  source:
  - security
  generated: '2026-11-06'
  method: derived
image: https://4dmoleculartherapeutics.com/wp-content/uploads/4dmt-fb-card-scaled.jpg
url: https://raw.githubusercontent.com/api-evangelist/4d-molecular-therapeutics-4dmt/refs/heads/main/apis.yml
x-type: company
x-source: harvest:secondary-market
x-tier: stub
x-tier-reason: harvest
specificationVersion: '0.20'
created: '2026-09-05'
modified: '2026-09-05'
tags:
- Company
- Biotechnology
- Gene Therapy
- Genetic Medicine
- Life Sciences
- Pharmaceuticals
- Clinical Trials
- Ophthalmology
apis: []
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: DomainSecurity
  url: security/4d-molecular-therapeutics-4dmt-domain-security.yml
- type: Website
  url: https://4dmoleculartherapeutics.com/
- type: TermsOfService
  url: https://4dmoleculartherapeutics.com/terms-of-service/
- type: PrivacyPolicy
  url: https://4dmoleculartherapeutics.com/privacy-notice/
- type: LLMsTxt
  name: llms.txt (site-wide SEO index, not an API index)
  url: llms/4d-molecular-therapeutics-4dmt-llms.txt
x-enrichment:
  date: '2026-09-05'
  status: minimal
  artifacts_added: 3
  pass: local-v3
x-coverage:
  state: none
  reason: not-a-software-company
  detail: '4DMT is a clinical-stage gene therapy developer whose product is a drug, not software: its entire public site is
    18 WordPress marketing pages (about, pipeline, technology, patients, careers, investors, contact) with no developer, docs,
    or API section anywhere in its sitemap, and the only machine-readable JSON on the domain is the CMS-default WordPress
    REST API at /wp-json, which is Automattic''s contract running under 4DMT''s name rather than an API 4DMT designed, documented,
    or offers to anyone.'
  evidence:
  - url: https://4dmoleculartherapeutics.com/openapi.json
    status: 404
  - url: https://4dmoleculartherapeutics.com/.well-known/agent-card.json
    status: 404
  - url: https://4dmoleculartherapeutics.com/page-sitemap.xml
    status: 200
  - url: https://4dmoleculartherapeutics.com/wp-json
    status: 200
  - url: https://4dmoleculartherapeutics.com/llms.txt
    status: 200
  checked: '2026-09-05'

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