Zetagen Therapeutics

Zetagen Therapeutics is a private, clinical-stage biopharmaceutical company founded in 2015 and based in Syracuse, New York, where it has operated from laboratory space in the Central New York Biotech Accelerator at SUNY Upstate Medical University since 2017. It develops locally administered small-molecule therapies for metastatic and primary cancers to bone and other organs, built on a proprietary "Zeta" platform derived from the company's discovery of a new molecular pathway acting through the Met5-enkephalin / opioid growth factor receptor signalling axis. Its oncology pipeline includes ZetaMet (Zeta-BC-003) for metastatic breast cancer to bone, which received FDA Breakthrough Device Designation in December 2021 and Health Canada authorisation for a Phase 2a study in January 2022 and reported Phase 2a results at ASCO in June 2026; ZetaMet-P (Zeta-PC-004) for prostate cancer; ZetaMAST (Zeta-MBC-005) for metastatic breast cancer in liver; Zeta-BC-007; and ZetaOnc. Its osteologic programme is ZetaFuse, a synthetic osteoinductive bone graft studied in anterior cervical discectomy and fusion. The company reached 64 worldwide patents in 2024, has been funded by NCI and NIAMS grants, a $5.34M Series A, a $9.79M Series B and an oversubscribed Series B1 closed in November 2025, and its shares trade on secondary markets. Zetagen Therapeutics runs no developer program and publishes no product API, developer portal or API documentation. The only machine-readable surface reachable without credentials is the WordPress REST content API behind zetagen.com, catalogued here.

Zetagen Therapeutics publishes 9 APIs on the APIs.io network, including Content API, Discovery API, Downloads API, and 6 more. Tagged areas include Company, biopharmaceuticals, oncology, bone-health, and orthopedics.

Zetagen Therapeutics’ developer surface includes product news, authentication, and 28 more developer resources.

🌐 Visit website 📡 Source on GitHub

18.8/100 emerging ▬ flat Agent 30/100 agent aware Full breakdown ↓
scored 2026-08-12 · rubric v0.11.0

9 APIs

Companybiopharmaceuticalsoncologybone-healthorthopedicsclinical-trialslife-sciencesdrug-developmentmedical-devicescontent-api

Kin Score

Kin Score How this is scored →
scored 2026-08-12 · rubric v0.11.0

Composite quality — 18.8/100 · emerging

Contract Quality 2.9 / 21

Developer Ergonomics 2.1 / 17

Commercial Clarity 1.8 / 17

Operational Transparency 0.0 / 11

Governance 1.2 / 10

Discoverability 6.9 / 9

Regulatory Posture 3.9 / 15

Agent readiness — 30/100 · agent aware

Machine-Readable Contract 18 / 18

Agentic Access Contract 0 / 10

MCP Server 0 / 12

Machine-Readable Auth 10 / 10

Idempotency 0 / 9

Stable Error Semantics 8 / 8

Request/Response Examples 0 / 7

Rate-Limit Signaling 0 / 7

Typed Event Surface 0 / 6

Agent Skills 5 / 5

Well-Known Catalog 0 / 4

Consent & Bot Identity 0 / 3

A2A Agent Card 0 / 8

Dry-Run / Simulate Mode 0 / 4

Regulatory Posture applies to this provider. Its tags matched the Health regime, so Regulatory Posture carries 15 points of the composite. If this regime is wrong for your business, say so on your provider repo — the applicability map is public and we will correct it.

The six quality facets above are damped to 85 points between them, because the conditional facet above carries the other 15. That is why each facet's contribution is shown against a damped maximum: raising a quality facet moves the composite by 85% of its nominal weight, not 100%. The full arithmetic is at apis.io/rating/.

Improve this rating by publishing the missing artifacts — every area above can be raised, and the full rubric is at apis.io/rating/. This rating is computed from github.com/api-evangelist/zetagen-therapeutics: open an issue to ask a question, or submit a pull request to add artifacts. Want it done for you? Prioritized profiling — $2,500 →

APIs 9

Individual APIs this provider publishes, each with its own machine-readable definition.

Get Started 1

Portal, sign-up, and the first successful call

ClinicalTrials

ClinicalTrials

Agent Surfaces 3

MCP servers, agent skills, and machine-readable catalogs

WellKnown

WellKnown

LLMsTxt

LLMsTxt

AgentSkill

AgentSkill

Design & Contract 5

Pagination, idempotency, versioning, errors, and events

Conventions

Conformance

ErrorCatalog

Lifecycle

DataModel

Access & Security 2

Authentication, authorization, and security posture

Authentication

Authentication

DomainSecurity

DomainSecurity

Operate 3

Status, limits, changes, and where to get help

RegulatoryStatus

RegulatoryStatus

PressReleases

PressReleases

Contact

Contact

Commercial 1

Pricing, plans, and the legal terms of use

PrivacyPolicy

PrivacyPolicy

Company 5

The organization behind the API

Website

About

News

BlogRSS

LinkedIn

Other 10

Properties that don't map to a standard resource type

Overlay

Science

Oncology

Research

ExpandedAccessPolicy

Publications

PatientResources

CookiePolicy

Disclaimer

SecondaryMarket

Scroll for all 10

Source (apis.yml)

aid: zetagen-therapeutics
name: Zetagen Therapeutics
description: Zetagen Therapeutics is a private, clinical-stage biopharmaceutical company founded in 2015 and based in Syracuse,
  New York, where it has operated from laboratory space in the Central New York Biotech Accelerator at SUNY Upstate Medical
  University since 2017. It develops locally administered small-molecule therapies for metastatic and primary cancers to bone
  and other organs, built on a proprietary "Zeta" platform derived from the company's discovery of a new molecular pathway
  acting through the Met5-enkephalin / opioid growth factor receptor signalling axis. Its oncology pipeline includes ZetaMet
  (Zeta-BC-003) for metastatic breast cancer to bone, which received FDA Breakthrough Device Designation in December 2021
  and Health Canada authorisation for a Phase 2a study in January 2022 and reported Phase 2a results at ASCO in June 2026;
  ZetaMet-P (Zeta-PC-004) for prostate cancer; ZetaMAST (Zeta-MBC-005) for metastatic breast cancer in liver; Zeta-BC-007;
  and ZetaOnc. Its osteologic programme is ZetaFuse, a synthetic osteoinductive bone graft studied in anterior cervical discectomy
  and fusion. The company reached 64 worldwide patents in 2024, has been funded by NCI and NIAMS grants, a $5.34M Series A,
  a $9.79M Series B and an oversubscribed Series B1 closed in November 2025, and its shares trade on secondary markets. Zetagen
  Therapeutics runs no developer program and publishes no product API, developer portal or API documentation. The only machine-readable
  surface reachable without credentials is the WordPress REST content API behind zetagen.com, catalogued here.
image: https://zetagen.com/wp-content/uploads/2021/08/zetagen-logo.png
url: https://raw.githubusercontent.com/api-evangelist/zetagen-therapeutics/refs/heads/main/apis.yml
x-type: company
x-source: harvest:secondary-market
x-tier: profiled
x-tier-reason: enriched
specificationVersion: '0.20'
created: '2026-08-05'
modified: '2026-08-05'
tags:
- Company
- biopharmaceuticals
- oncology
- bone-health
- orthopedics
- clinical-trials
- life-sciences
- drug-development
- medical-devices
- content-api
apis:
- aid: zetagen-therapeutics:zetagen-therapeutics-content-api
  name: Zetagen Therapeutics Content API
  description: Posts, pages and the block library.
  humanURL: https://developer.wordpress.org/rest-api/
  baseURL: https://zetagen.com/wp-json
  tags:
  - content
  properties:
  - type: OpenAPI
    url: openapi/zetagen-therapeutics-content-api-openapi.yml
  - type: Authentication
    url: authentication/zetagen-therapeutics-authentication.yml
  - type: ErrorCatalog
    url: errors/zetagen-therapeutics-problem-types.yml
  - type: Conventions
    url: conventions/zetagen-therapeutics-conventions.yml
  - type: DataModel
    url: data-model/zetagen-therapeutics-data-model.yml
- aid: zetagen-therapeutics:zetagen-therapeutics-discovery-api
  name: Zetagen Therapeutics Discovery API
  description: Route index, registered types, taxonomies and statuses.
  humanURL: https://developer.wordpress.org/rest-api/
  baseURL: https://zetagen.com/wp-json
  tags:
  - discovery
  properties:
  - type: OpenAPI
    url: openapi/zetagen-therapeutics-discovery-api-openapi.yml
  - type: Authentication
    url: authentication/zetagen-therapeutics-authentication.yml
  - type: ErrorCatalog
    url: errors/zetagen-therapeutics-problem-types.yml
  - type: Conventions
    url: conventions/zetagen-therapeutics-conventions.yml
  - type: DataModel
    url: data-model/zetagen-therapeutics-data-model.yml
- aid: zetagen-therapeutics:zetagen-therapeutics-downloads-api
  name: Zetagen Therapeutics Downloads API
  description: WP Download Manager public search.
  humanURL: https://developer.wordpress.org/rest-api/
  baseURL: https://zetagen.com/wp-json
  tags:
  - downloads
  properties:
  - type: OpenAPI
    url: openapi/zetagen-therapeutics-downloads-api-openapi.yml
  - type: Authentication
    url: authentication/zetagen-therapeutics-authentication.yml
  - type: ErrorCatalog
    url: errors/zetagen-therapeutics-problem-types.yml
  - type: Conventions
    url: conventions/zetagen-therapeutics-conventions.yml
  - type: DataModel
    url: data-model/zetagen-therapeutics-data-model.yml
- aid: zetagen-therapeutics:zetagen-therapeutics-embed-api
  name: Zetagen Therapeutics Embed API
  description: oEmbed 1.0 provider.
  humanURL: https://developer.wordpress.org/rest-api/
  baseURL: https://zetagen.com/wp-json
  tags:
  - embed
  properties:
  - type: OpenAPI
    url: openapi/zetagen-therapeutics-embed-api-openapi.yml
  - type: Authentication
    url: authentication/zetagen-therapeutics-authentication.yml
  - type: ErrorCatalog
    url: errors/zetagen-therapeutics-problem-types.yml
  - type: Conventions
    url: conventions/zetagen-therapeutics-conventions.yml
  - type: DataModel
    url: data-model/zetagen-therapeutics-data-model.yml
- aid: zetagen-therapeutics:zetagen-therapeutics-media-api
  name: Zetagen Therapeutics Media API
  description: The 388-item media library.
  humanURL: https://developer.wordpress.org/rest-api/
  baseURL: https://zetagen.com/wp-json
  tags:
  - media
  properties:
  - type: OpenAPI
    url: openapi/zetagen-therapeutics-media-api-openapi.yml
  - type: Authentication
    url: authentication/zetagen-therapeutics-authentication.yml
  - type: ErrorCatalog
    url: errors/zetagen-therapeutics-problem-types.yml
  - type: Conventions
    url: conventions/zetagen-therapeutics-conventions.yml
  - type: DataModel
    url: data-model/zetagen-therapeutics-data-model.yml
- aid: zetagen-therapeutics:zetagen-therapeutics-people-api
  name: Zetagen Therapeutics People API
  description: Author records. Personal data — see x-personal-data. Documented for completeness; deliberately excluded from
    every packaged Agent Skill in this repo.
  humanURL: https://developer.wordpress.org/rest-api/
  baseURL: https://zetagen.com/wp-json
  tags:
  - people
  properties:
  - type: OpenAPI
    url: openapi/zetagen-therapeutics-people-api-openapi.yml
  - type: Authentication
    url: authentication/zetagen-therapeutics-authentication.yml
  - type: ErrorCatalog
    url: errors/zetagen-therapeutics-problem-types.yml
  - type: Conventions
    url: conventions/zetagen-therapeutics-conventions.yml
  - type: DataModel
    url: data-model/zetagen-therapeutics-data-model.yml
- aid: zetagen-therapeutics:zetagen-therapeutics-search-api
  name: Zetagen Therapeutics Search API
  description: Cross-content search.
  humanURL: https://developer.wordpress.org/rest-api/
  baseURL: https://zetagen.com/wp-json
  tags:
  - search
  properties:
  - type: OpenAPI
    url: openapi/zetagen-therapeutics-search-api-openapi.yml
  - type: Authentication
    url: authentication/zetagen-therapeutics-authentication.yml
  - type: ErrorCatalog
    url: errors/zetagen-therapeutics-problem-types.yml
  - type: Conventions
    url: conventions/zetagen-therapeutics-conventions.yml
  - type: DataModel
    url: data-model/zetagen-therapeutics-data-model.yml
- aid: zetagen-therapeutics:zetagen-therapeutics-seo-api
  name: Zetagen Therapeutics Seo API
  description: Yoast SEO head metadata.
  humanURL: https://developer.wordpress.org/rest-api/
  baseURL: https://zetagen.com/wp-json
  tags:
  - seo
  properties:
  - type: OpenAPI
    url: openapi/zetagen-therapeutics-seo-api-openapi.yml
  - type: Authentication
    url: authentication/zetagen-therapeutics-authentication.yml
  - type: ErrorCatalog
    url: errors/zetagen-therapeutics-problem-types.yml
  - type: Conventions
    url: conventions/zetagen-therapeutics-conventions.yml
  - type: DataModel
    url: data-model/zetagen-therapeutics-data-model.yml
- aid: zetagen-therapeutics:zetagen-therapeutics-taxonomy-api
  name: Zetagen Therapeutics Taxonomy API
  description: Categories and tags.
  humanURL: https://developer.wordpress.org/rest-api/
  baseURL: https://zetagen.com/wp-json
  tags:
  - taxonomy
  properties:
  - type: OpenAPI
    url: openapi/zetagen-therapeutics-taxonomy-api-openapi.yml
  - type: Authentication
    url: authentication/zetagen-therapeutics-authentication.yml
  - type: ErrorCatalog
    url: errors/zetagen-therapeutics-problem-types.yml
  - type: Conventions
    url: conventions/zetagen-therapeutics-conventions.yml
  - type: DataModel
    url: data-model/zetagen-therapeutics-data-model.yml
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: Overlay
  url: overlays/zetagen-therapeutics-content-overlay.yaml
- type: Website
  url: https://zetagen.com/
- type: About
  url: https://zetagen.com/our-company/
- type: Science
  url: https://zetagen.com/the-science/
- type: Oncology
  url: https://zetagen.com/oncology-sector/
- type: Research
  url: https://zetagen.com/research-overview/
- type: RegulatoryStatus
  url: https://zetagen.com/research-overview/regulatory-status/
- type: ClinicalTrials
  url: https://zetagen.com/research-overview/clinical-trials/
- type: ExpandedAccessPolicy
  url: https://zetagen.com/research-overview/expanded-access-policy/
- type: Publications
  url: https://zetagen.com/news/publications/
- type: News
  url: https://zetagen.com/news/
- type: PressReleases
  url: https://zetagen.com/news/press-releases/
- type: BlogRSS
  url: https://zetagen.com/feed/
- type: Contact
  url: https://zetagen.com/contact-us/
- type: PatientResources
  url: https://zetagen.com/walk-with-you/
- type: PrivacyPolicy
  url: https://zetagen.com/privacy-statement-us/
- type: CookiePolicy
  url: https://zetagen.com/cookie-policy-eu/
- type: Disclaimer
  url: https://zetagen.com/disclaimer/
- type: LinkedIn
  url: https://www.linkedin.com/company/zetagen-therapeutics
- type: SecondaryMarket
  url: https://forgeglobal.com/zetagen-therapeutics_stock/
- type: Authentication
  url: authentication/zetagen-therapeutics-authentication.yml
- type: Conventions
  url: conventions/zetagen-therapeutics-conventions.yml
- type: Conformance
  url: conformance/zetagen-therapeutics-conformance.yml
- type: ErrorCatalog
  url: errors/zetagen-therapeutics-problem-types.yml
- type: Lifecycle
  url: lifecycle/zetagen-therapeutics-lifecycle.yml
- type: DataModel
  url: data-model/zetagen-therapeutics-data-model.yml
- type: WellKnown
  url: well-known/zetagen-therapeutics-well-known.yml
- type: DomainSecurity
  url: security/zetagen-therapeutics-domain-security.yml
- type: LLMsTxt
  url: llms/zetagen-therapeutics-llms.txt
- type: AgentSkill
  url: skills/_index.yml
x-enrichment:
  date: '2026-08-05'
  status: enriched
  artifacts_added: 16
  pass: local-v1

Zetagen Therapeutics

Kin Score

APIs 9

Zetagen Therapeutics Content API

Zetagen Therapeutics Discovery API

Zetagen Therapeutics Downloads API

Zetagen Therapeutics Embed API

Zetagen Therapeutics Media API

Zetagen Therapeutics People API

Zetagen Therapeutics Search API

Zetagen Therapeutics Seo API

Zetagen Therapeutics Taxonomy API

Security Posture 2

Zetagen Therapeutics Authentication

Zetagen Therapeutics Domain Security

Resources