Totus Medicines

Totus Medicines is a biopharmaceutical company developing precision oral medicines against historically "undruggable" disease targets. The company's OmniDEL discovery platform screens targets in their normal cellular environment to identify potent, selective covalent small molecules, drawing on precedents like penicillin and AZT. Totus is advancing a pipeline focused on oncology and immunology & inflammation (I&I), including TOS-358, a covalent PI3Ka inhibitor, and a first-in-class covalent IRF5 inhibitor in clinical development. Headquartered in Emeryville, California, Totus was surfaced as a portfolio company of DCVC and profiled in the API Evangelist network. As a clinical-stage drug-discovery company, Totus publishes no public developer API surface; this profile captures its corporate identity, web properties, and security posture.

Totus Medicines is profiled on the APIs.io network. Tagged areas include Company, Biopharmaceutical, Drug Discovery, Covalent Small Molecules, and Oncology.

Totus Medicines’ developer surface includes product news, support, and 14 more developer resources.

🌐 Visit website 📡 Source on GitHub

9.4/100 minimal ▬ flat Agent 0/100 human only Full breakdown ↓
scored 2026-09-08 · rubric v0.20.0

0 APIs

Company Biopharmaceutical Drug DiscoveryCovalent Small MoleculesOncology Immunology Precision Medicine Biotechnology

Kin Score

Kin Score How this is scored →
scored 2026-09-08 · rubric v0.20.0

Composite quality — 9.4/100 · minimal

Contract Quality 0.0 / 25

Developer Ergonomics 1.0 / 20

Access Clarity 2.1 / 20

Operational Transparency 1.4 / 13

Contract Governance 0.0 / 12

Discoverability 5.0 / 10

Agent readiness — 0/100 · human only

Machine-Readable Contract 0 / 18

Agentic Access Contract 0 / 10

Documented Reversibility 0 / 6

MCP Server 0 / 12

Machine-Readable Auth 0 / 10

Idempotency 0 / 9

Stable Error Semantics 0 / 8

Request/Response Examples 0 / 7

Rate-Limit Signaling 0 / 7

Typed Event Surface 0 / 6

Agent Skills 0 / 5

Well-Known Catalog 0 / 4

Consent & Bot Identity 0 / 3

A2A Agent Card 0 / 8

Dry-Run / Simulate Mode 0 / 4

Delegated User Identity 0 / 6

Protected Resource Metadata 0 / 5

Registration Without a Human 0 / 6

Agentic Commerce Well-Known Document 0 / 5

Create-or-Update Ergonomics could not be measured. We hold no machine-readable contract for this provider to read, so there is nothing to measure a write surface against. Excluded rather than scored zero: never-measured and measured-empty are different facts. Publishing an OpenAPI is what makes this facet — and several others — scorable at all.

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Security Posture 2

Authentication, domain security, vulnerability disclosure, and trust-center signals.

Totus Medicines Domain Security

TLSv1.3 · HSTS · DMARC

SECURITY

Totus Medicines Vulnerability Disclosure

security.txt · contact published

SECURITY

Resources

Agent Surfaces 1

MCP servers, agent skills, and machine-readable catalogs

WellKnown

WellKnown

Access & Security 4

Authentication, authorization, and security posture

VulnerabilityDisclosure

VulnerabilityDisclosure

Security

Security

DomainSecurity

DomainSecurity

SecurityTxt

SecurityTxt

Operate 1

Status, limits, changes, and where to get help

Support

Support

Commercial 1

Pricing, plans, and the legal terms of use

PrivacyPolicy

PrivacyPolicy

Company 7

The organization behind the API

Website

About

News

Partnerships

Careers

LinkedIn

Twitter

Twitter

Scroll for all 7

Other 2

Properties that don't map to a standard resource type

Platform

Platform

Pipeline

Pipeline

Source (apis.yml)

aid: totus-medicines
deliveryModel:
  model: unknown
  open_source: false
  commercial: false
  callable_host: false
  label: Delivery model not determined — needs a product licence on record
  confidence: low
  source:
  - none
  generated: '2026-08-28'
  method: derived
accessModel:
  pricing: unknown
  onboarding: unknown
  trial: false
  try_now: false
  public: false
  label: Unknown
  confidence: low
  source: []
  generated: '2026-07-22'
  method: derived
image: https://kinlane-images.s3.amazonaws.com/shared/apis-json/icons/totus-medicines.png
name: Totus Medicines
description: Totus Medicines is a biopharmaceutical company developing precision oral medicines against historically "undruggable"
  disease targets. The company's OmniDEL discovery platform screens targets in their normal cellular environment to identify
  potent, selective covalent small molecules, drawing on precedents like penicillin and AZT. Totus is advancing a pipeline
  focused on oncology and immunology & inflammation (I&I), including TOS-358, a covalent PI3Ka inhibitor, and a first-in-class
  covalent IRF5 inhibitor in clinical development. Headquartered in Emeryville, California, Totus was surfaced as a portfolio
  company of DCVC and profiled in the API Evangelist network. As a clinical-stage drug-discovery company, Totus publishes
  no public developer API surface; this profile captures its corporate identity, web properties, and security posture.
url: https://raw.githubusercontent.com/api-evangelist/totus-medicines/refs/heads/main/apis.yml
x-type: company
x-source: vc-portfolio
x-backed-by:
- dcvc
x-tier: stub
x-tier-reason: portfolio-lead
specificationVersion: '0.23'
created: '2026-07-17'
modified: '2026-07-21'
tags:
- Company
- Biopharmaceutical
- Drug Discovery
- Covalent Small Molecules
- Oncology
- Immunology
- Precision Medicine
- Biotechnology
apis: []
common:
- type: VulnerabilityDisclosure
  url: security/totus-medicines-vulnerability-disclosure.yml
- type: Security
  url: security/totus-medicines-vulnerability-disclosure.yml
- type: DomainSecurity
  url: security/totus-medicines-domain-security.yml
- type: Website
  url: https://www.totusmedicines.com/
- type: About
  url: https://www.totusmedicines.com/about-us
- type: Platform
  url: https://www.totusmedicines.com/platform
- type: Pipeline
  url: https://www.totusmedicines.com/pipeline
- type: News
  url: https://www.totusmedicines.com/news
- type: Partnerships
  url: https://www.totusmedicines.com/partnerships
- type: Support
  url: https://www.totusmedicines.com/contact-us
- type: PrivacyPolicy
  url: https://www.totusmedicines.com/privacy-policy
- type: Careers
  url: https://boards.greenhouse.io/totusmedicines
- type: LinkedIn
  url: https://www.linkedin.com/company/totusmedicines
- type: Twitter
  url: https://twitter.com/Totus_Medicines
- type: SecurityTxt
  url: well-known/totus-medicines-security.txt
- type: WellKnown
  url: well-known/totus-medicines-well-known.yml
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
x-enrichment:
  date: '2026-07-21'
  status: enriched
  artifacts_added: 4
  pass: local-v1

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