Spark Therapeutics

Spark Therapeutics is a Philadelphia-based gene therapy company founded in 2013 with roots at Children's Hospital of Philadelphia (CHOP). Spark developed Luxturna (voretigene neparvovec-rzyl), the first FDA-approved gene therapy for a genetic disease in the United States, approved in December 2017 for the treatment of inherited retinal disease caused by biallelic RPE65 mutations. Roche acquired Spark Therapeutics in December 2019 for approximately $4.3 billion, and Spark has since been integrated into the Roche Group, operating as a Genentech subsidiary. The original sparktx.com domain now redirects to gene.com/spark. Spark does not publish any public developer APIs, OpenAPI specifications, SDKs, or GitHub organization. As a pharmaceutical/biotech operating under Roche, Spark's public technical surface is limited to patient and prescriber information for Luxturna and adverse event reporting channels (FDA MedWatch and 1-855-SPARKTX).

Spark Therapeutics is profiled on the APIs.io network. Tagged areas include Biotechnology, Pharmaceuticals, Gene Therapy, Rare Disease, and Ophthalmology.

🌐 Visit website 📡 Profile data on GitHub

7.5/100 minimal ▬ flat Agent 0/100 human only Full breakdown ↓
scored 2026-11-06 · rubric v0.27.0 · Show this score on your site →

0 APIs

Biotechnology Pharmaceuticals Gene Therapy Rare Disease OphthalmologyInherited Retinal DiseaseRoche SubsidiaryLife Sciences

Kin Score

Kin Score How this is scored →
scored 2026-11-06 · rubric v0.27.0

Composite quality — 7.5/100 · minimal

Contract Quality 0.0 / 21

Developer Ergonomics 0.0 / 17

Access Clarity 0.0 / 17

Operational Transparency 1.2 / 11

Contract Governance 1.4 / 10

Discoverability 3.6 / 9

Regulatory Posture 2.0 / 15

Agent readiness — 0/100 · human only

Machine-Readable Contract 0 / 18

Agentic Access Contract 0 / 10

Documented Reversibility 0 / 6

MCP Server 0 / 12

Machine-Readable Auth 0 / 10

Idempotency 0 / 9

Stable Error Semantics 0 / 8

Request/Response Examples 0 / 7

Rate-Limit Signaling 0 / 7

Typed Event Surface 0 / 6

Agent Skills 0 / 5

Well-Known Catalog 0 / 4

Consent & Bot Identity 0 / 3

A2A Agent Card 0 / 8

Dry-Run / Simulate Mode 0 / 4

Delegated User Identity 0 / 6

Protected Resource Metadata 0 / 5

Registration Without a Human 0 / 6

Agentic Commerce Well-Known Document 0 / 5

Pagination 5 / 5

Distinct Operations 3 / 3

MCP Tool Quality 6 / 6

Regulatory Posture applies to this provider. Its tags matched the Health regime, so Regulatory Posture carries 15 points of the composite. If this regime is wrong for your business, say so on your provider repo — the applicability map is public and we will correct it.

Create-or-Update Ergonomics could not be measured. We hold no machine-readable contract for this provider to read, so there is nothing to measure a write surface against. Excluded rather than scored zero: never-measured and measured-empty are different facts. Publishing an OpenAPI is what makes this facet — and several others — scorable at all.

The six quality facets above are damped to 85 points between them, because the conditional facet above carries the other 15. That is why each facet's contribution is shown against a damped maximum: raising a quality facet moves the composite by 85% of its nominal weight, not 100%. The full arithmetic is at apis.io/rating/.

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Agent readiness — checks not met, largest first (exact, from this profile):

Machine-Readable Contract +18 pts — api_specs includes an OpenAPI document
MCP Server +12 pts — deployment.mode + probe verdict on the mcp/ manifest, not the pointer; an unprobed slug falls back to authorship
Agentic Access Contract +10 pts — agentic_access artifact present (x-agentic-access), graded by author
Machine-Readable Auth +10 pts — a served openid-configuration/oauth-authorization-server carrying `issuer` (served), else the securitySchemes class in the provider OpenAPIs — bound (mutualTLS, DPoP, Signature) > negotiable (oauth2 authorizationCode/clientCredentials, openIdConnect) > bearer (http bearer, apiKey)
Idempotency +9 pts — OpenAPI mutating operations declare an idempotency key — a header, a request-body property, or a named de-duplication token whose own description says so (verified); else common[].type matches /idempoten/i (documented)
Stable Error Semantics +8 pts — OpenAPI $refs a shared error schema across 4xx/5xx responses (verified), else common[].type includes ErrorCatalog / ErrorCodes / DeclineCodes

13 more unmet checks in the Agent Readiness table above.

Kin Score — facets with the most composite points still available (weight × headroom):

Contract Quality scores 0.0 — up to +25.0 composite points
Developer Ergonomics scores 0.0 — up to +20.0 composite points
Access Clarity scores 0.0 — up to +20.0 composite points

Each check links to what satisfies it. Publish the artifact, or tell us where it already lives, and the score moves on the next scoring run.

Improve this rating by publishing the missing artifacts — every area above can be raised, and the full rubric is at apis.io/rating/. Every facet and dimension name above is a link: it opens that measurement's own page — what it means, the exact checks that feed it, how the whole catalog distributes on it, and the providers at the top of it. This rating is computed from the provider profile at artifacts.apis.io/spark-therapeutics/apis.yml: open an issue on github.com/api-evangelist/spark-therapeutics to ask a question or point us at an artifact you publish. Submit an artifact on GitHub — free → Manage your own listing — the Influence plan, $499/mo →

Markets this provider is in provisional

The Kin Score Market layer reads a provider inside its market: its position, and how deep its integrations go. Depth is only comparable within a position. Provisional and unweighted: not part of the Kin Score or agent readiness.

Market	Position	Depth	Registered MCP server	Declares compatibility
Cell & Gene Therapy	standard	60.7	-	-

Registered MCP server and declares compatibility are report only — not weighted. Undeclared means we found nothing we can read, so there is no number: we never infer integrations.

Security Posture 2

Authentication, domain security, vulnerability disclosure, and trust-center signals.

Spark Therapeutics Domain Security

TLSv1.3 · HSTS · DMARC

SECURITY

Spark Therapeutics Vulnerability Disclosure

Hackerone · security.txt · contact published

SECURITY

Resources

Get Started 1

Portal, sign-up, and the first successful call

PatientPortal

PatientPortal

Design & Contract 1

Pagination, idempotency, versioning, errors, and events

Vocabulary

Vocabulary

Access & Security 2

Authentication, authorization, and security posture

VulnerabilityDisclosure

VulnerabilityDisclosure

DomainSecurity

DomainSecurity

Company 2

The organization behind the API

Website

Website

LinkedIn

Other 4

Properties that don't map to a standard resource type

ProductInformation

ParentCompany

ParentCompany

Wikipedia

Source (apis.yml)

aid: spark-therapeutics
name: Spark Therapeutics
deliveryModel:
  model: unknown
  open_source: false
  commercial: false
  callable_host: false
  label: Delivery model not determined — needs a product licence on record
  confidence: low
  source:
  - none
  generated: '2026-08-28'
  method: derived
specificationVersion: '0.23'
accessModel:
  pricing: unknown
  onboarding: unknown
  trial: false
  try_now: false
  public: false
  label: Unknown
  confidence: low
  source:
  - security
  generated: '2026-11-06'
  method: derived
image: https://kinlane-images.s3.amazonaws.com/shared/apis-json/icons/spark-therapeutics.png
url: https://raw.githubusercontent.com/api-evangelist/spark-therapeutics/refs/heads/main/apis.yml
modified: '2026-05-23'
description: Spark Therapeutics is a Philadelphia-based gene therapy company founded in 2013 with roots at Children's Hospital
  of Philadelphia (CHOP). Spark developed Luxturna (voretigene neparvovec-rzyl), the first FDA-approved gene therapy for a
  genetic disease in the United States, approved in December 2017 for the treatment of inherited retinal disease caused by
  biallelic RPE65 mutations. Roche acquired Spark Therapeutics in December 2019 for approximately $4.3 billion, and Spark
  has since been integrated into the Roche Group, operating as a Genentech subsidiary. The original sparktx.com domain now
  redirects to gene.com/spark. Spark does not publish any public developer APIs, OpenAPI specifications, SDKs, or GitHub organization.
  As a pharmaceutical/biotech operating under Roche, Spark's public technical surface is limited to patient and prescriber
  information for Luxturna and adverse event reporting channels (FDA MedWatch and 1-855-SPARKTX).
apis: []
common:
- type: VulnerabilityDisclosure
  url: security/spark-therapeutics-vulnerability-disclosure.yml
- type: DomainSecurity
  url: security/spark-therapeutics-domain-security.yml
- type: Website
  url: https://www.gene.com/spark
- type: ProductInformation
  url: https://luxturna.com
- type: PatientPortal
  url: https://mysparkgeneration.com
- type: ParentCompany
  url: https://www.roche.com
- type: ParentCompany
  url: https://www.gene.com
- type: LinkedIn
  url: https://www.linkedin.com/company/spark-therapeutics
- type: Wikipedia
  url: https://en.wikipedia.org/wiki/Spark_Therapeutics
- type: Vocabulary
  url: https://raw.githubusercontent.com/api-evangelist/spark-therapeutics/refs/heads/main/vocabulary/spark-therapeutics-vocabulary.yml
tags:
- Biotechnology
- Pharmaceuticals
- Gene Therapy
- Rare Disease
- Ophthalmology
- Inherited Retinal Disease
- Roche Subsidiary
- Life Sciences
x-parent: genentech
x-relationship: product

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