Schrödinger is a New York-headquartered (NASDAQ: SDGR) computational science company that develops a physics-based and AI-driven molecular simulation platform used across drug discovery and materials science. Its flagship desktop modeling environment is Maestro (MS Maestro for materials science), which integrates a deep stack of computational tools — Glide (docking), FEP+ (free energy perturbation), Desmond (molecular dynamics), Jaguar (quantum chemistry), Prime (protein structure prediction), BioLuminate (biologics), LigPrep, QikProp, SiteMap, and WaterMap — together with the Schrödinger-maintained PyMOL visualization system. LiveDesign is the cloud-native enterprise design lab where chemists, biologists, and program teams collaborate on molecules, run computational workflows, and integrate experimental data; it exposes a snap-in API framework for connecting in-house and third-party tooling. The Schrödinger Python API (current release 2026-1) is the primary developer surface, providing programmatic access to molecular structures, Maestro automation, jobcontrol, Glide, FEP+, Desmond, Jaguar, MacroModel, Prime, BioLuminate, and LiveDesign integration (login, export, dataset and column management). Schrödinger also ships KNIME extensions, command-line drivers for every computational product, and maintains a meaningful open-source footprint on GitHub — including PyMOL, maeparser, coordgenlibs, sketcher, gpusimilarity, csmiles, and the fixed-data-table-2 React component. The business has two segments — software licensing to global pharma, biotech, and materials companies, and a co-developed and proprietary drug discovery pipeline. There is no public developer signup or self-serve REST API; access to the platform, Python API, and LiveDesign is gated through commercial licensing and the my.schrodinger.com customer portal.
Schrödinger is profiled on the APIs.io network. Tagged areas include Drug Discovery, Computational Chemistry, Molecular Simulation, Physics-Based Modeling, and Free Energy Perturbation.
Schrödinger’s developer surface includes developer portal, documentation, support, training material, tooling, engineering blog, signup flow, and 48 more developer resources.
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Agent readiness — checks not met, largest first (exact, from this profile):
Idempotency+9 pts — OpenAPI mutating operations declare an idempotency key — a header, a request-body property, or a named de-duplication token whose own description says so (verified); else common[].type matches /idempoten/i (documented)
Stable Error Semantics+8 pts — OpenAPI $refs a shared error schema across 4xx/5xx responses (verified), else common[].type includes ErrorCatalog / ErrorCodes / DeclineCodes
A2A Agent Card+8 pts — a2a/-a2a.yml manifest, graded on conformance.grade against A2A 1.0.0
9 more unmet checks in the Agent Readiness table above.
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Online certification courses and a free learning portal for the platform
Drug discovery pipeline — proprietary and partnered programs including SGR-1505 (MALT1 inhibitor) and collaborations such as Lilly TuneLab integration into LiveDesign
Two-segment business — software licensing to global pharma, biotech, and materials companies plus a co-developed and proprietary drug discovery portfolio
Public company listed on NASDAQ under the ticker SDGR
Access is gated through commercial licensing and the my.schrodinger.com customer portal; no self-serve public REST API and no public developer signup
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