Relay Therapeutics
Relay Therapeutics is a Cambridge, Massachusetts clinical-stage precision medicines company (NASDAQ: RLAY) using protein motion to drug historically intractable oncology and genetic-disease targets. Its Dynamo platform combines full-length protein engineering, cryo-EM, ambient-temperature X-ray crystallography, long-timescale molecular dynamics, machine learning, virtual screening, activity- and ligand-based screening, and an ML-powered DNA-encoded library (REL-DEL) to design molecules against conformational states that static structures miss. The clinical pipeline is led by zovegalisib (RLY-2608), described as the first allosteric, pan-mutant, isoform-selective PI3K-alpha inhibitor, in Phase 3 for HR+/HER2- breast cancer and Phase 1/2 for vascular anomalies and PROS; RLY-8161, an NRAS- selective inhibitor, is in Phase 1/2 for NRAS-mutant solid tumors; an alpha-galactosidase A non-inhibitory chaperone for Fabry disease is in discovery; lirafugratinib (RLY-4008, FGFR2) was out-licensed to Elevar Therapeutics in December 2024. Relay has no public developer API, SDK, or open-source release; the Dynamo platform is proprietary internal R&D tooling, and the company's GitHub organization currently has no public repositories. The commercial surface is therapeutic candidates, clinical partnerships, and out-licensing rather than data products.
Relay Therapeutics is profiled on the APIs.io network. Tagged areas include Drug Discovery, Precision Medicine, Oncology, Genetic Disease, and Protein Motion.
Relay Therapeutics’ developer surface includes GitHub presence and 12 more developer resources.
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