PAQ Therapeutics

PAQ Therapeutics is a clinical-stage biotechnology company headquartered at 100 Summit Drive, Burlington, Massachusetts, developing targeted protein degradation (TPD) medicines for KRAS-driven cancers. Rather than inhibiting the KRAS oncoprotein, PAQ's autophagy-based degrader chemistry recruits the cell's own natural degradation machinery to remove the protein outright, an approach the company applies to the KRAS mutations found in roughly a quarter of human tumors, most notably lung, colorectal and pancreatic cancer. Its lead program, PT0511, is a pan-KRAS degrader that dosed its first patient in a Phase 1 trial in January 2026. The company was co-founded by Nan Ji (Chief Executive Officer) and Huaixiang Hao (Head of Research), with Andrew Krivoshik as Chief Medical Officer. PAQ Therapeutics is a therapeutics developer, not a software vendor: it operates a four-page corporate WordPress site and publishes no API, SDK, developer portal or machine-readable contract of any kind.

PAQ Therapeutics is profiled on the APIs.io network. Tagged areas include Company, Biotechnology, Pharmaceuticals, Oncology, and Therapeutics.

PAQ Therapeutics’ developer surface includes engineering blog and 7 more developer resources.

🌐 Visit website 📡 Source on GitHub

9.5/100 minimal ▬ flat Agent 0/100 human only Front door AI 1/6 silent saas Full breakdown ↓
scored 2026-09-21 · rubric v0.22.0

0 APIs

Company Biotechnology Pharmaceuticals Oncology Therapeutics Drug Discovery Targeted Protein Degradation Life Sciences Clinical Stage Massachusetts

Kin Score

Kin Score How this is scored →
scored 2026-09-21 · rubric v0.22.0

Composite quality — 9.5/100 · minimal

Contract Quality 0.0 / 21

Developer Ergonomics 0.4 / 17

Access Clarity 3.6 / 17

Operational Transparency 0.0 / 11

Contract Governance 0.0 / 10

Discoverability 4.3 / 9

Regulatory Posture 2.6 / 15

Agent readiness — 0/100 · human only

Machine-Readable Contract 0 / 18

Agentic Access Contract 0 / 10

Documented Reversibility 0 / 6

MCP Server 0 / 12

Machine-Readable Auth 0 / 10

Idempotency 0 / 9

Stable Error Semantics 0 / 8

Request/Response Examples 0 / 7

Rate-Limit Signaling 0 / 7

Typed Event Surface 0 / 6

Agent Skills 0 / 5

Well-Known Catalog 0 / 4

Consent & Bot Identity 0 / 3

A2A Agent Card 0 / 8

Dry-Run / Simulate Mode 0 / 4

Delegated User Identity 0 / 6

Protected Resource Metadata 0 / 5

Registration Without a Human 0 / 6

Agentic Commerce Well-Known Document 0 / 5

Regulatory Posture applies to this provider. Its tags matched the Health regime, so Regulatory Posture carries 15 points of the composite. If this regime is wrong for your business, say so on your provider repo — the applicability map is public and we will correct it.

Create-or-Update Ergonomics could not be measured. We hold no machine-readable contract for this provider to read, so there is nothing to measure a write surface against. Excluded rather than scored zero: never-measured and measured-empty are different facts. Publishing an OpenAPI is what makes this facet — and several others — scorable at all.

The six quality facets above are damped to 85 points between them, because the conditional facet above carries the other 15. That is why each facet's contribution is shown against a damped maximum: raising a quality facet moves the composite by 85% of its nominal weight, not 100%. The full arithmetic is at apis.io/rating/.

Improve this rating by publishing the missing artifacts — every area above can be raised, and the full rubric is at apis.io/rating/. Every facet and dimension name above is a link: it opens that measurement's own page — what it means, the exact checks that feed it, how the whole catalog distributes on it, and the providers at the top of it. This rating is computed from github.com/api-evangelist/paq-therapeutics: open an issue to ask a question, or submit a pull request to add artifacts. Submit an artifact on GitHub — free → Manage your own listing — the Influence plan, $499/mo →

Security Posture 1

Authentication, domain security, vulnerability disclosure, and trust-center signals.

Paq Therapeutics Domain Security

TLSv1.3

SECURITY

Resources

Agent Surfaces 1

MCP servers, agent skills, and machine-readable catalogs

LLMsTxt

LLMsTxt

Access & Security 1

Authentication, authorization, and security posture

DomainSecurity

DomainSecurity

Commercial 2

Pricing, plans, and the legal terms of use

PrivacyPolicy

PrivacyPolicy

TermsOfService

TermsOfService

Company 4

The organization behind the API

Website

Website

Blog

Blog

BlogRSS

BlogRSS

LinkedIn

Source (apis.yml)

aid: paq-therapeutics
name: PAQ Therapeutics
description: 'PAQ Therapeutics is a clinical-stage biotechnology company headquartered at 100 Summit Drive, Burlington, Massachusetts,
  developing targeted protein degradation (TPD) medicines for KRAS-driven cancers. Rather than inhibiting the KRAS oncoprotein,
  PAQ''s autophagy-based degrader chemistry recruits the cell''s own natural degradation machinery to remove the protein outright,
  an approach the company applies to the KRAS mutations found in roughly a quarter of human tumors, most notably lung, colorectal
  and pancreatic cancer. Its lead program, PT0511, is a pan-KRAS degrader that dosed its first patient in a Phase 1 trial
  in January 2026. The company was co-founded by Nan Ji (Chief Executive Officer) and Huaixiang Hao (Head of Research), with
  Andrew Krivoshik as Chief Medical Officer. PAQ Therapeutics is a therapeutics developer, not a software vendor: it operates
  a four-page corporate WordPress site and publishes no API, SDK, developer portal or machine-readable contract of any kind.'
url: https://raw.githubusercontent.com/api-evangelist/paq-therapeutics/refs/heads/main/apis.yml
deliveryModel:
  model: saas
  open_source: false
  commercial: true
  callable_host: false
  label: Hosted service · you call their endpoint
  confidence: medium
  source:
  - pricing
  generated: '2026-08-28'
  method: derived
accessModel:
  pricing: unknown
  onboarding: unknown
  trial: false
  try_now: false
  public: false
  label: Unknown
  confidence: low
  source:
  - security
  generated: '2026-09-02'
  method: derived
image: https://www.paqtx.com/wp-content/uploads/2023/03/paq-therapeutics.jpg
x-type: company
x-source: harvest:secondary-market
x-tier: stub
x-tier-reason: harvest
specificationVersion: '0.20'
created: '2026-08-26'
modified: '2026-08-26'
tags:
- Company
- Biotechnology
- Pharmaceuticals
- Oncology
- Therapeutics
- Drug Discovery
- Targeted Protein Degradation
- Life Sciences
- Clinical Stage
- Massachusetts
apis: []
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: LLMsTxt
  url: llms/paq-therapeutics-llms.txt
- type: DomainSecurity
  url: security/paq-therapeutics-domain-security.yml
- type: Website
  url: https://www.paqtx.com/
- type: Blog
  url: https://www.paqtx.com/news-archive/
- type: BlogRSS
  url: https://www.paqtx.com/feed/
- type: PrivacyPolicy
  url: https://www.paqtx.com/privacy-policy/
- type: TermsOfService
  url: https://www.paqtx.com/terms-and-conditions/
- type: LinkedIn
  url: https://www.linkedin.com/company/paq-therapeutics
x-enrichment:
  date: '2026-08-26'
  status: minimal
  artifacts_added: 3
  pass: local-v1
x-coverage:
  state: none
  reason: not-a-software-company
  detail: PAQ Therapeutics is a clinical-stage drug developer whose entire public surface is a four-page WordPress marketing
    site — no api., developer., developers., docs. or portal. subdomain resolves in DNS for paqtx.com, and every contract-discovery
    path on www.paqtx.com (/openapi.json, /swagger.json, /graphql, /api-docs, /llms.txt, every /.well-known/*) returns 404.
  evidence:
  - url: https://www.paqtx.com/openapi.json
    status: 404
  - url: https://www.paqtx.com/.well-known/agent-card.json
    status: 404
  - url: https://www.paqtx.com/llms.txt
    status: 404
  - url: https://api.paqtx.com/
    status: 0
  - url: https://www.paqtx.com/
    status: 200
  checked: '2026-08-26'

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